EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

monosodium laevo-aspartate
monosodium L-aspartate

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Name:sodium (2S)-2-amino-4-hydroxy-4-oxobutanoate
CAS Number: 3792-50-5Picture of molecule3D/inchi
Other(deleted CASRN):16079-55-3
ECHA EINECS - REACH Pre-Reg:223-264-0
Molecular Weight:156.09335928
Formula:C4 H7 N O4 Na
NMR Predictor:Predict (works with chrome, Edge or firefox)
Name:disodium (2S)-2-aminobutanedioate
CAS Number: 17090-93-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:241-155-6
Nikkaji Web:J184.561F
Molecular Weight:177.06718856
Formula:C4 H5 N Na2 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:special dietary and nutritional additives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 263.00 to 265.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.002890 mmHg @ 25.00 °C. (est)
Flash Point: 236.00 °F. TCC ( 113.33 °C. )
logP (o/w): -0.669 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
hair conditioning
Anhui Haibei
Sodium L-aspartate
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
L-Aspartic acid sodium salt monohydrate
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
special dietary and nutritional additives
Recommendation for monosodium laevo-aspartate usage levels up to:
 not for fragrance use.
Recommendation for monosodium laevo-aspartate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):3792-50-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23672344
National Institute of Allergy and Infectious Diseases:Data
sodium (2S)-2-amino-4-hydroxy-4-oxobutanoate
disodium (2S)-2-aminobutanedioate
 sodium (2S)-2-amino-4-hydroxy-4-oxobutanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23672344
Pubchem (sid):135047744
 disodium (2S)-2-aminobutanedioate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):21806
Pubchem (sid):170751
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
 buffering agents
 hair conditioning
Occurrence (nature, food, other):note
 found in nature
 aspartate monosodium salt
 sodium (2S)-2-amino-4-hydroxy-4-oxobutanoate
 sodium aspartate
monosodium aspartate
 sodium hydrogen laevo-aspartate
 sodium L-aspartate
monosodium L-aspartate
 sodium laevo-aspartate


PubMed:pH-responsive self-assembly and conformational transition of partially propyl-esterified poly(alpha,beta-L-aspartic acid) as amphiphilic biodegradable polyanion.
PubMed:Recovery of Cu(II) and Cd(II) by a chelating resin containing aspartate groups.
PubMed:Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene.
PubMed:Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells.
PubMed:Sustainable enzymatic preparation of polyaspartate using a bacterial protease.
PubMed:Phase-resolved fluorescence study of mono-L-aspartyl chlorin E6.
PubMed:Effect of plant oils and aspartate on rumen fermentation in vitro.
PubMed:Determination of free acetaldehyde in total blood for investigating the effect of aspartate on metabolism of alcohol in mice.
PubMed:Cardiac function and glycogen content after twenty-four-hour preservation with various metabolic substrates.
PubMed:Promoting effect of monosodium aspartate, but not glycine, on renal pelvis and urinary bladder carcinogenesis in rat induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
PubMed:Inner retinal contributions to the primate photopic fast flicker electroretinogram.
PubMed:Activation mechanism of Ca(2+)-sensitive transient outward current in rabbit ventricular myocytes.
PubMed:Effects of the intracerebroventricular administration of ketamine on centrogenic arrhythmias in anesthetized rats.
PubMed:[Extracellular photoreceptor potential of albino rats].
PubMed:Light-evoked changes in near-infrared transmission by the ON and OFF channels of the anuran retina.
PubMed:Effect of sodium aspartate on the recovery of the rat heart from long-term hypothermic storage.
PubMed:Light and dark induced variations of the c-wave voltage of the chicken eye after treatment with sodium aspartate.
PubMed:Hydrophobic interaction chromatography in alkaline pH.
PubMed:Sensitivity of ERG components from dark-adapted goldfish retinas treated with APB.
PubMed:Electroretinogram c-wave and slow PIII of the rabbit: changes in peak time and amplitude under various stimulus durations.
PubMed:The time course of the light-induced extracellular potassium change around receptors and at the vitreal surface compared with the time course of slow PIII wave in the isolated rabbit retina.
PubMed:Four spectral classes of cone in the retinas of birds.
PubMed:Nucleotide ligands protect the inter-domain regions of the multifunctional polypeptide CAD against limited proteolysis, and also stabilize the thermolabile part-reactions of the carbamoyl-phosphate synthase II domains within the CAD polypeptide.
PubMed:The effect of lead on photoreceptor response amplitude--influence of removing external calcium and bleaching rhodopsin.
PubMed:Effect of carbohydrate ingestion on plasma aspartate concentrations in infant mice administered sodium L-aspartate.
PubMed:Effect of chloride and glutamate ions on in vitro protein synthesis by the moderate halophile Vibrio costicola.
PubMed:The effect of lead on photoreceptor response amplitude--influence of the light stimulus.
PubMed:The ultraviolet receptor of bird retinas.
PubMed:A reweighting of receptor mechanisms in the ground squirrel retina: PIII and B-wave spectral sensitivity functions.
PubMed:Rapid dark adaptation of bullfrog rods is delayed by barium.
PubMed:Fractional recording and component analysis of primate LERG: separation of photoreceptor and other retinal potentials.
PubMed:The action of phosphodiesterase inhibitors on the hypersensitivity of frog photoreceptor.
PubMed:Regional effects of sodium aspartate and sodium glutamate on protein synthesis in the retina.
PubMed:Lead-induced experimental lesions of the testis and their treatment.
PubMed:Stereospecificity of sodium borohydride reduction of Schiff bases at the active site of aspartate aminotransferase.
PubMed:Similarities between the c-wave and slow PIII in the rabbit eye.
PubMed:The sodium effect of Bacillus subtilis growth on aspartate.
PubMed:Acetylcholine-induced current in perfused rat myoballs.
PubMed:Retinal detachment from hyperosmotic intravitreal injection.
PubMed:Barium delays the onset of rapid dark adaptation in bullfrog cones.
PubMed:Somatic, behavioral, and reproductive disturbances in mice following neonatal administration of sodium L-aspartate.
PubMed:Combined effect of veratridine and sodium aspartate on the rabbit retinas in vitro.
PubMed:[Corneal response to 'off' in the intact rabbit eye].
PubMed:Adaptive properties of the b-wave and the PIII in the perfused isolated carp retina.
PubMed:Intracellular recordings from gecko photoreceptors during light and dark adaptation.
PubMed:Response of primate cones to sinusoidally flickering homochromatic stimuli.
PubMed:[Demonstration of subcomponents of PIII in the ERG of isolated rabbit retina using sodium asparaginate].
PubMed:Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate.
PubMed:Intraretinal isolation of P3 subcomponents in the isolated rabbit retina after treatment with sodium aspartate.
PubMed:[Action of sodium aspartate on oxygen consumption of rat heart slices and homogenates in an oxygenated atmosphere without CO2].
PubMed:[Action of small doses of sodium aspartate on the evolution of hemorrhagic shock in rabbits].
PubMed:[Action of variable concentrations of sodium aspartate on the respiratory activity of homogenates of rat liver and brain tissue and on sections of cerebral cortex stimulated with KCl in pure oxygen without CO2].
PubMed:Adaptation in skate photoreceptors.
PubMed:[The effect of sodium aspartate on some serum protease activities and lipid components in dogs].
PubMed:[Effects of temperature and sodium aspartate on the ERG of the albino rabbit retina].
PubMed:[Effects of temperature and sodium aspartate on the ERG of the albino rabbit retina].
PubMed:Fermentation studies with Streptomyces griseus. II. Synthetic media for the production of streptomycin.
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a of the non-essential amino acids commonly occurring in the l-form. it is found in animals and plants, especially in sugar cane and sugar beets. it may be a neurotransmitter.
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