(+)-alpha-bisabolol, 23178-88-3

Articles:

PubMed:Alpha-bisabolol, not a matter for cancer therapy. Commentary: "Research on the immunosuppressive activity of ingredients contained in sunscreens".

PubMed:α-bisabolol is an effective proapoptotic agent against BCR-ABL(+) cells in synergism with Imatinib and Nilotinib.

PubMed:Assessing the Chemical Composition and Antimicrobial Activity of Essential Oils from Brazilian Plants-Eremanthus erythropappus (Asteraceae), Plectrantuns barbatus, and P. amboinicus (Lamiaceae).

PubMed:Randomized, controlled study of innovative spray formulation containing ozonated oil and α-bisabolol in the topical treatment of chronic venous leg ulcers.

PubMed:A Multi-Target Approach toward the Development of Novel Candidates for Antidermatophytic Activity: Ultrastructural Evidence on α-Bisabolol-Treated Microsporum gypseum.

PubMed:(-)-α-Bisabolol, a Promising Oral Compound for the Treatment of Visceral Leishmaniasis.

PubMed:In vitro evaluation of (-)α-bisabolol as a promising agent against Leishmania amazonensis.

PubMed:(-)-α-Bisabolol inhibits preferentially electromechanical coupling on rat isolated arteries.

PubMed:Enantioselective microbial synthesis of the indigenous natural product (-)-α-bisabolol by a sesquiterpene synthase from chamomile (Matricaria recutita).

PubMed:α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.

PubMed:In vivo effect of alpha-bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice.

PubMed:The antimicrobial activity of alpha-bisabolol and tea tree oil against Solobacterium moorei, a Gram-positive bacterium associated with halitosis.

PubMed:STAT-3 inhibitory bisabolanes from Carthamus glaucus.

PubMed:Synthesis and cytotoxicity evaluation of natural alpha-bisabolol beta-D-fucopyranoside and analogues.

PubMed:An untargeted metabolomic approach in the chemotaxonomic assessment of two Salvia species as a potential source of α-bisabolol.

PubMed:Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis.

PubMed:Determination of alpha-bisabolol and d-panthenol in cosmetic products by gas chromatography.

PubMed:In-vitro characterization of the pharmacological effects induced by (-)-α-bisabolol in rat smooth muscle preparations.

PubMed:Antitumor effects of α-bisabolol against pancreatic cancer.

PubMed:Anti-nociceptive and anti-inflammatory activities of (-)-α-bisabolol in rodents.

PubMed:(-)-α-Bisabolol-induced gastroprotection is associated with reduction in lipid peroxidation, superoxide dismutase activity and neutrophil migration.

PubMed:Inhibitory effects of (-)-α-bisabolol on LPS-induced inflammatory response in RAW264.7 macrophages.

PubMed:Attenuation of visceral nociception by α-bisabolol in mice: investigation of mechanisms.

PubMed:Enhanced topical delivery of small hydrophilic or lipophilic active agents and epidermal growth factor by fractional radiofrequency microporation.

PubMed:Essential-oil composition of Daucus carota ssp. major (Pastinocello Carrot) and nine different commercial varieties of Daucus carota ssp. sativus fruits.

PubMed:Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells.

PubMed:Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.

PubMed:(-)-α-Bisabolol attenuates visceral nociception and inflammation in mice.

PubMed:Whitening effect of alpha-bisabolol in Asian women subjects.

PubMed:alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

PubMed:Chemical composition and biological activities of essential oils of Eremanthus erythropappus (DC) McLeisch (Asteraceae).

PubMed:Distinct mechanisms of relaxation to bioactive components from chamomile species in porcine isolated blood vessels.

PubMed:Studies on the Origin of (-)-alpha-Bisabolol and Chamazulene in Chamomile Preparations; Part I. Investigations by Isotope Ratio Mass Spectrometry (IRMS).

PubMed:The essential oil of Populus balsamifera buds: its chemical composition and cytotoxic activity.

PubMed:Genome mining reveals two novel bacterial sesquiterpene cyclases: (-)-germacradien-4-ol and (-)-epi-α-bisabolol synthases from Streptomyces citricolor.

PubMed:Evaluation of the sesquiterpene (-)-alpha-bisabolol as a novel peripheral nervous blocker.

PubMed:Activity of (-)alpha-bisabolol against Leishmania infantum promastigotes.

PubMed:Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms.

PubMed:Composition and Bioactivities of an (E)-β-Farnesene Chemotype of Chamomile (Matricaria chamomilla) Essential Oil from Nepal.

PubMed:Composition and biological activity of the essential oil from leaves of Plinia cerrocampanensis, a new source of alpha-bisabolol.

PubMed:Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.

PubMed:Validation of a high-performance liquid chromatography method for the determination of (-)-alpha-bisabolol from particulate systems.

PubMed:Antimicrobial activity of nerolidol and its derivatives against airborne microbes and further biological activities.

PubMed:Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity.

PubMed:Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis.

PubMed:Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.

PubMed:Chemical composition, antibacterial, antifungal and antioxidant activities of Algerian Eryngium tricuspidatum L. essential oil.

PubMed:Fast quality assessment of German chamomile (Matricaria chamomilla L.) by headspace solid-phase microextraction: influence of flower development stage.

PubMed:Bioactivity of the essential oil of an argentine collection of Acanthospermum hispidum (Asteraceae).

PubMed:Composition of the essential oils and antibacterial activities of Hymenocrater yazdianus, Stachys obtusicrena and Nepeta asterotricha three Labiatae herbs growing wild in Iran.

PubMed:Antihyperalgesic and antiedematous activities of bisabolol-oxides-rich matricaria oil in a rat model of inflammation.

PubMed:Antinociceptive and anti-edematous activities of the essential oils of two Balkan endemic Laserpitium species.

PubMed:Activity of Matricaria chamomilla essential oil against anisakiasis.

PubMed:New terpenoids in cultivated and wild chamomile (in vivo and in vitro).

PubMed:Composition and antimicrobial activity of the essential oil of Heracleum thomsonii (Clarke) from the cold desert of the western Himalayas.

PubMed:Psychopharmacological profile of Chamomile (Matricaria recutita L.) essential oil in mice.

PubMed:Antiplasmodial volatile extracts from Cleistopholis patens Engler & Diels and Uvariastrum pierreanum Engl. (Engl. & Diels) (Annonaceae) growing in Cameroon.

PubMed:Persistency assessment and aerobic biodegradation of selected cyclic sesquiterpenes present in essential oils.

PubMed:Enhancement and mechanism of transdermal absorption of terpene-induced propranolol hydrochloride.

PubMed:Composition and antifungal activity of the essential oil from the rhizome and roots of Ferula hermonis.

PubMed:Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid.

PubMed:Alpha-bisabolol: unexpected plant-derived weapon in the struggle against tumour survival?

PubMed:Determination of alpha-bisabolol in human blood by micro-HPLC-ion trap MS and head space-GC-MS methods.

PubMed:(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.

PubMed:alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells.

PubMed:The ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates.

PubMed:Phase solubility studies of pure (-)-alpha-bisabolol and camomile essential oil with beta-cyclodextrin.

PubMed:Effect of dissolution profile and (-)-alpha-bisabolol on the gastrotoxicity of acetylsalicylic acid.

PubMed:Fragrance material review on alpha-bisabolol.

PubMed:[Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)].

PubMed:Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay.

PubMed:Asymmetric epoxidation of homoallylic alcohols and application in a concise total synthesis of (-)-alpha-bisabolol and (-)-8-epi-alpha-bisabolol.

PubMed:Performance evaluation of a versatile multidimensional chromatographic preparative system based on three-dimensional gas chromatography and liquid chromatography-two-dimensional gas chromatography for the collection of volatile constituents.

PubMed:Chemical composition and antibacterial activity of essential oil of Nepeta graciliflora Benth. (Lamiaceae).

PubMed:Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum.

PubMed:Characterization of Volatile Compounds of Eleven Achillea Species from Turkey and Biological Activities of Essential Oil and Methanol Extract of A. hamzaoglui Arabacı & Budak.

PubMed:Abundance of volatile organic compounds in white ash phloem and emerald ash borer larval frass does not attract Tetrastichus planipennisi in a Y-tube olfactometer.

PubMed:Essential oils and distilled straws of lavender and lavandin: a review of current use and potential application in white biotechnology.

PubMed:Cloning and characterization of a farnesyl pyrophosphate synthase from Matricaria recutita L. and its upregulation by methyl jasmonate.

PubMed:Composition of the essential oil of Stachys benthamiana Boiss. from the south of Iran.

PubMed:Mechanisms of depigmentation by alpha-bisabolol.

PubMed:In Vitro Antileishmanial Activity of Essential Oil of Vanillosmopsis arborea (Asteraceae) Baker.

PubMed:Antitumor activity of the protein and small molecule component fractions from Agrocybe aegerita through enhancement of cytokine production.

PubMed:[Pharmacological investigations with compounds of chamomile ii. new investigations on the antiphlogistic effects of (-)-alpha-bisabolol and bisabolol oxides (author's transl)].

PubMed:[Ether and ester of (minus)-alpha-bisabolol and analogous mono- and sesquiterpenoids with antiphlogistic effect].

PubMed:[On the inflammation inhibitory effect of (-)-alpha-bisabolol, an essential component of chamomilla oil].

PubMed:[Synthesis of alpha-bisabolol--a spasmolytically active sequiterpenic alcohol].

PubMed:Determination of the ploidy level in chamomile (Chamomilla recutita (L.) Rausch.) strains rich in alpha-bisabolol.

PubMed:(+)-4-epi-alpha-bisabolol as a major sesquiterepene constituent in the leaves of two Rosa rugosa hybrids, Martin Frobisher and Vanguard.

PubMed:[Pharmacological studies with compounds of chamomile. IV. Studies on toxicity of (-)-alpha-bisabolol (author's transl)].

PubMed:[Pharmacological investigations with compounds of chamomile i. on the pharmacology of (-)-alpha-bisabolol and bisabolol oxides (review) (author's transl)].

PubMed:Bisabolol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide, and KATP+ channels.

PubMed:Characterization of volatile and semi-volatile compounds in green and fermented leaves of Bergenia crassifolia L. by gas chromatography-mass spectrometry and ID-CUBE direct analysis in real time-high resolution mass spectrometry.

PubMed:Antimicrobial activity of essential oils and five terpenoid compounds against Campylobacter jejuni in pure and mixed culture experiments.

PubMed:Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.

PubMed:Chemical composition and biological activity of the essential oil of Amomum biflorum.

PubMed:Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem.

PubMed:VOC contamination in hospital, from stationary sampling of a large panel of compounds, in view of healthcare workers and patients exposure assessment.

PubMed:Volatile compounds of flowers and leaves of Sideritis italica (Miller) Greuter et Burdet (Lamiaceae), a plant used as mountain tea.

PubMed:Chemical composition and antiphytoviral activity of essential oil of Micromeria graeca.

PubMed:Content and composition of the essential oil of Chamomilla recutita (L.) Rauschert from some European countries.

PubMed:Detailed analysis of the essential oil from Cistus albidus L. by combination of GC/RI, GC/MS and 13C-NMR spectroscopy.

PubMed:Quinoline alkaloids, coumarins and volatile constituents of Helietta longifoliata.

PubMed:Hydrophilic solutes in modified carbon dioxide extraction-prediction of the extractability using molecular dynamic simulation.

PubMed:Determination of radix ginseng volatile oils at different ages by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry.

PubMed:In vitro anti-inflammatory effect of Carthamus lanatus L.

PubMed:Production of yarrow (Achillea millefolium L.) in Norway: essential oil content and quality.

PubMed:In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.

PubMed:Evaluation of thermal-oxidative stability and antiglioma activity of Zanthoxylum tingoassuiba essential oil entrapped into multi- and unilamellar liposomes.

PubMed:Control of Tetranychus urticae Koch by extracts of three essential oils of chamomile, marjoram and Eucalyptus.

PubMed:[Study of tolerance and efficacy of cosmetic preparations with lenitive action in atopic dermatitis in children].

PubMed:Essential oil from aerial parts of of Betonica grandiflora Willd. from Iran.

PubMed:Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus.

PubMed:Antiaggregation Potential of Padina gymnospora against the Toxic Alzheimer's Beta-Amyloid Peptide 25-35 and Cholinesterase Inhibitory Property of Its Bioactive Compounds.

PubMed:Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.

PubMed:Chemical variation of the essential oil of Prangos uloptera DC. at different stages of growth.

PubMed:Application of a multidimensional gas chromatography system with simultaneous mass spectrometric and flame ionization detection to the analysis of sandalwood oil.

PubMed:Composition of volatile organic compounds in flowers of Astragalus sahendi.

PubMed:Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides.

PubMed:Effect of magnesium on essential oil formation of genetically transformed and non-transformed chamomile cultures.

PubMed:Volatile secondary metabolite pattern of callus cultures of Chamomilla recutita.

PubMed:Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.

PubMed:Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate.

PubMed:Chemical composition and insecticidal activity of essential oils from Vanillosmopsis pohlii baker against Bemisia argentifolii.

PubMed:Anthocyanin, bisabolol and phenylammonialyase activity in cell cultures of Populus deltoides.

PubMed:The cyclization of farnesyl diphosphate and nerolidyl diphosphate by a purified recombinant delta-cadinene synthase.

PubMed:[Analysis of the chemical constituents of essential oil from Anaphalis aureopunctata by GC-MS].

PubMed:Variability of the essential oil content and composition of chamomile (Matricaria recutita L.) affected by weather conditions.

PubMed:Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate.

PubMed:Essential oil from Zanthoxylum tingoassuiba loaded into multilamellar liposomes useful as antimicrobial agents.

PubMed:Treatment of pruritus in mild-to-moderate atopic dermatitis with a topical non-steroidal agent.

PubMed:Essential oil composition of three Peperomia species from the Amazon, Brazil.

PubMed:Gastroprotective mechanism of Vanillosmopsis arborea bark essential oil.

PubMed:Antennal and behavioral responses of Cis boleti to fungal odor of Trametes gibbosa.

PubMed:Synthetic organic chemistry based on small ring compounds.

PubMed:Anti-irritants II: Efficacy against cumulative irritation.

PubMed:[GC-MS analysis of essential oils from Radix Angelicae Pubescentis].

PubMed:A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.).

PubMed:The in vitro pharmacological activities and a chemical investigation of three South African Salvia species.

PubMed:Composition and antibacterial activity of essential oil of Lantana achyranthifolia Desf. (Verbenaceae).

PubMed:[Investigation of chemical composition of propolis extract].

PubMed:Analysis by gas chromatography-mass spectrometry of the essential oil from the aerial parts of Pimpinella junoniae Ceb. & Ort., gathered in La Gomera, Canary Islands, Spain.

PubMed:Chemical variations in the essential oil of Sideritis tragoriganum.

PubMed:A study of the production of essential oils in chamomile hairy root cultures.

PubMed:Winter chemical defense of Alaskan balsam poplar against snowshoe hares.

PubMed:South African Salvia species: a review of biological activities and phytochemistry.

PubMed:[Characterization of chemical components of essential oil from cupitulum of Chrysanthemum morifolium cultivated in Tongxiang city].

PubMed:Quantitative co-occurrence of sesquiterpenes; a tool for elucidating their biosynthesis in Indian sandalwood, Santalum album.

PubMed:Anti-irritants I: Dose-response in acute irritation.

PubMed:The hairless guinea-pig as a model for treatment of acute irritation in humans.

PubMed:The hairless guinea-pig as a model for treatment of cumulative irritation in humans.

PubMed:Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases.

PubMed:Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes.

PubMed:Daucane sesquiterpenes from Ferula hermonis.

PubMed:Comprehensive two-dimensional gas chromatography with flame ionization and time-of-flight mass spectrometry detection: qualitative and quantitative analysis of West Australian sandalwood oil.

PubMed:Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L.

PubMed:Effects of some components of the essential oil of chamomile, Chamomilla recutita, on histamine release from rat mast cells.

PubMed:Devil's-claw (Proboscidea louisianica), essential oil and its components : Potential allelochemical agents on cotton and wheat.

PubMed:[Absorption, distribution and metabolism of [14C]-levomenol in the skin].

PubMed:[Production of essential oils by cell-suspensions of Matricaria chamomilla in a two phase system.].

PubMed:Comparative analysis of chemical compositions and antimicrobial activities of essential oils from Abies holophylla and Abies koreana activities of essential oils from Abies holophylla and Abies koreana.

(+)-alpha-bisabolol
(R)-6-methyl-2-((R)-4-methyl-cyclohex-3-enyl)-hept-5-en-2-ol

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(+)-alpha-bisabolol (R)-6-methyl-2-((R)-4-methyl-cyclohex-3-enyl)-hept-5-en-2-ol

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(+)-alpha-bisabolol
(R)-6-methyl-2-((R)-4-methyl-cyclohex-3-enyl)-hept-5-en-2-ol