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citral acid isomerized
3,7-dimethyl-2,6-octadienal acid-isomerized

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Name:3,7-dimethyl-2,6-octadienal acid-isomerized
CAS Number: 90480-35-6
ECHA EC Number:291-768-8
FDA UNII: Search
Category:fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
Augustus Oils
Ernesto Ventós
Ernesto Ventós
Indukern F&F
Lluch Essence
The Lermond Company
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for citral acid isomerized flavor usage levels up to:
 not for flavor use.
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
3,7-dimethyl-2,6-octadienal acid-isomerized
 3,7-dimethyl-2,6-octadienal acid-isomerized
Pubchem (sid):135272716
Other Information:
HMDB (The Human Metabolome Database):Search
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
3,7-dimethyl-2,6-octadienal acid-isomerized


PubMed:The Discovery of Citral-Like Thiophenes in Fried Chicken.
PubMed:Biological properties of citral and its potential protective effects against cytotoxicity caused by aspirin in the IEC-6 cells.
PubMed:The plant secondary metabolite citral alters water status and prevents seed formation in Arabidopsis thaliana.
PubMed:Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation.
PubMed:The Effect of Chemical Composition and Bioactivity of Several Essential Oils on Tenebrio molitor (Coleoptera: Tenebrionidae).
PubMed:Fumigant, contact, and repellent activities of essential oils against the darkling beetle, Alphitobius diaperinus.
PubMed:Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.
PubMed:Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
PubMed:Citral is renoprotective for focal segmental glomerulosclerosis by inhibiting oxidative stress and apoptosis and activating Nrf2 pathway in mice.
PubMed:Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms.
PubMed:Effect of mitotic inducers and retinoic acid blocker on expression of pluripotent genes in ES cells derived from early stage in vitro-produced embryos in buffalo.
PubMed:The in vitro study of apoptosis in NB4 cell induced by citral.
PubMed:Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans.
PubMed:Binary Au/MWCNT and ternary Au/ZnO/MWCNT nanocomposites: synthesis, characterisation and catalytic performance.
PubMed:Citral inhibits cell proliferation and induces apoptosis and cell cycle arrest in MCF-7 cells.
PubMed:Citral: identifying a threshold for induction of dermal sensitization.
PubMed:A phase II detoxification enzyme inducer from lemongrass: identification of citral and involvement of electrophilic reaction in the enzyme induction.
PubMed:Mechanism of inhibition of aldehyde dehydrogenase by citral, a retinoid antagonist.
PubMed:Citral, an inhibitor of retinoic acid synthesis, modifies chick limb development.
PubMed:Blockade of the initiation of murine odontogenesis in vitro by citral, an inhibitor of endogenous retinoic acid synthesis.
PubMed:Retinoic acid can be produced from excentric cleavage of beta-carotene in human intestinal mucosa.
PubMed:Immunocytochemistry of epithelial markers in citral-induced prostate hyperplasia in rats.
PubMed:Modulation of tumor promotion in mouse skin by the food additive citral (3,7-dimethyl-2,6-octadienal).
PubMed:The metabolism of 3,7-dimethyl-2,6-octadienal (citral) in rat hepatic mitochondrial and cytosolic fractions. Interactions with aldehyde and alcohol dehydrogenases.
PubMed:Oxidation of retinol to retinoic acid as a requirement for biological activity in mouse epidermis.
PubMed:Selective oocyte degeneration and impaired fertility in rats treated with the aliphatic monoterpene, Citral.
PubMed:Influence of vitamin A and 3,7-dimethyl-2,6-octadienal (citral) on the effect of benzo(a)pyrene on hamster trachea in organ culture.
None found
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