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4-hydroxyflavanone
4H-1-benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-

Supplier Sponsors

Name:2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
CAS Number: 6515-37-3Picture of molecule3D/inchi
FDA UNII: 5K6L8O868Y
Nikkaji Web:J285.123G
MDL:MFCD00017705
XlogP3:2.80 (est)
Molecular Weight:240.25824000
Formula:C15 H12 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 447.53 °C. @ 760.00 mm Hg (est)
Flash Point: 345.00 °F. TCC ( 174.00 °C. ) (est)
logP (o/w): 2.720 (est)
Soluble in:
 water, 416.5 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Carbosynth
For experimental / research use only.
4-Hydroxyflavanone
ExtraSynthese
For experimental / research use only.
4'-Hydroxyflavanone
Penta International
4-HYDROXYFLAVANONE
Santa Cruz Biotechnology
For experimental / research use only.
4'-Hydroxyflavanone
Sigma-Aldrich: Aldrich
For experimental / research use only.
4-Hydroxyflavanone
sds
TCI AMERICA
For experimental / research use only.
4'-Hydroxyflavanone >98.0%(HPLC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for 4-hydroxyflavanone usage levels up to:
 not for fragrance use.
 
Recommendation for 4-hydroxyflavanone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :165506
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Chemidplus:0006515373
 
References:
 2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):165506
Pubchem (sid):135121758
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C14241
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.19.4300
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
4H-1-benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-
2,3-dihydro-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4'-hydroxy flavanone
2-(4-hydroxy-phenyl)-chroman-4-one
4'-hydroxyflavanone
2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
2-(4-hydroxyphenyl)chroman-4-one
 

Articles:

PubMed:Regiospecificity of human UDP-glucuronosyltransferase isoforms in chalcone and flavanone glucuronidation determined by metal complexation and tandem mass spectrometry.
PubMed:Three new phenolic compounds from the roots of Glycyrrhiza yunnanensis.
PubMed:Bioconversion of 7-hydroxyflavanone: isolation, characterization and bioactivity evaluation of twenty-one phase I and phase II microbial metabolites.
PubMed:Evaluation of novel amylose and cellulose-based chiral stationary phases for the stereoisomer separation of flavanones by means of nano-liquid chromatography.
PubMed:4'-Hydroxyflavanone suppresses activation of sterol regulatory element-binding proteins and de novo lipid synthesis.
PubMed:Microbial metabolism. Part 12. Isolation, characterization and bioactivity evaluation of eighteen microbial metabolites of 4'-hydroxyflavanone.
PubMed:Optical isomer separation of flavanones and flavanone glycosides by nano-liquid chromatography using a phenyl-carbamate-propyl-beta-cyclodextrin chiral stationary phase.
PubMed:[Studies on chemical constituents from seed of Psoralea corylifolia].
PubMed:Chiral separation of hydroxyflavanones in cyclodextrin-modified capillary zone electrophoresis using sulfated cyclodextrins as chiral selectors.
PubMed:[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].
PubMed:Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.
PubMed:Effect of different flavonoids on collagen synthesis in human fibroblasts.
PubMed:Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.
PubMed:Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences.
PubMed:Synthesis and anti-inflammatory effect of chalcones and related compounds.
PubMed:Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
PubMed:Aromatase inhibition by flavonoids.
PubMed:Microbiological transformation of (+/-)-flavanone and (+/-)-isoflavanone.
 
Notes:
None found
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