doxl amine succinate
ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-, butanedioate (1:1)

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  BOC Sciences

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  CODE154654 CODE154654
  Product(s):
  562-10-7 Doxylamine Succinate >98%
  Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.

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  Penta International Corporation

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  CODE154654 CODE154654
  Product(s):
  04-91800 DOXLAMINE SUCCINATE USP

Name: butanedioicacid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine CAS Number: 562-10-7 3D/inchi ECHA EINECS - REACH Pre-Reg: 209-228-7 FDA UNII: V9BI9B5YI2 MDL: MFCD00056168 Molecular Weight: 388.46416000 Formula: C21 H28 N2 O5 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: white powder (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 364.90 °C. @ 760.00 mm Hg (est) Vapor Pressure: 0.000016 mmHg @ 25.00 °C. (est) Flash Point: 346.00 °F. TCC ( 174.50 °C. ) (est) logP (o/w): 2.519 (est) Soluble in:   water, 7.438e+004 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. Doxylamine Succinate >98% Odor: characteristic Use: Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects. Penta International DOXLAMINE SUCCINATE USP Santa Cruz Biotechnology For experimental / research use only. Doxlamine Succinate Sigma-Aldrich: Sigma For experimental / research use only. Doxl Amine Succinate sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intravenous-mouse LD50 62 mg/kg Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. oral-mouse LD50 470 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. intravenous-rabbit LD50 49 mg/kg Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. oral-rabbit LD50 250 mg/kg Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. oral-rat LDLo 600 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: FOOD INTAKE (ANIMAL) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 37, Pg. 311, 1948. Dermal Toxicity: subcutaneous-mouse LD50 460 mg/kg Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. subcutaneous-rat LD50 440 mg/kg Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948. Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for doxl amine succinate usage levels up to:   not for fragrance use.   Recommendation for doxl amine succinate flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :11224 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 butanedioicacid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine Chemidplus:0000562107 EPA/NOAA CAMEO:hazardous materials RTECS:US9275000 for cas# 562-10-7   References:   butanedioicacid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine NIST Chemistry WebBook: Search Inchi Pubchem (cid): 11224 Pubchem (sid): 134977827   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): C19414 HMDB (The Human Metabolome Database): HMDB01936 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   alsadorm   bendectin   butanedioic acid compd. with N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)   butanedioic acid, compd. with N, N-dimethyl-2-[1-phenyl-1- (2-pyridinyl)ethoxy]ethanamine (1:1)   butanedioic acid, compd. with N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine (1:1)   butanedioicacid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine   contac nighttime cold medicine   decapryn   decarpyn succinate (1:1) N,N- dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine butanedioate N,N- dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine succinate (1:1) N,N- dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine butanedioate (1:1) N,N- dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine succinate (1:1) 2-(a-(2- dimethylaminoethoxy)-a-methylbenzyl)pyridine succinate   dimethylaminoethoxymethylbenzylpyridine succinate 2- dimethylaminoethoxyphenylmethyl-2-picoline succinate   doxlamine succinate   doxyl amine hydrogen succinate   ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-, butanedioate (1:1)   evigoa D   gittalun   hoggar N   mereprine   pyridine, 2-(a-(2-(dimethylamino)ethoxy)-a-methylbenzyl)-, succinate (1:1)   pyridine, 2-[a-[2- (dimethylamino)ethoxy]-a-methylbenzyl]-, succinate (1:1)   sedaplus   unisom   Articles:   None found yet. 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Notes: histamine h1 antagonist with pronounced sedative properties. it is used in allergies and as an antitussive, antiemetic, and hypnotic. doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.