hesperetin dihydrochalcone, 35400-60-3

Supplier Sponsors

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
Email:	Sales
US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
US Voice: 1-631-485-4226
US Fax: 1-631-614-7828
Europe	44-203-286-1088
Facebook
Twitter
Linkedin
Blog
Get the App!
CODE154079 CODE154079
Product(s):
35400-60-3 HESPERETIN DIHYDROCHALCONE 95%

Chemical sources Association Inc

Exchange of knowledge
Need This Item for Flavor? You can contact the Chemical Sources Association.
Events
Links
CODE154079 CODE154079
Product(s):

Name:	3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
CAS Number:	35400-60-3	3D/inchi
FDA UNII:	6FQ3Q8SSB7
Nikkaji Web:	J811.219C
MDL:	MFCD00016768
XlogP3-AA:	2.60 (est)
Molecular Weight:	304.29872000
Formula:	C16 H16 O6
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments:
mp: Decomposition >120�

Category:flavoring agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Flavoring:	2262 3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
FEMA Number:	4872 3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
FDA:	No longer provide for the use of these seven synthetic flavoring substances

Physical Properties:

Appearance:	slightly grey solid (est)
Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Boiling Point:	553.10 °C. @ 760.00 mm Hg (est)
Flash Point:	405.00 °F. TCC ( 207.00 °C. ) (est)
logP (o/w):	3.210 (est)
Soluble in:
	water, 63.05 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

HESPERETIN DIHYDROCHALCONE 95%

Carbosynth

For experimental / research use only.

4-Methoxy-2',4',6',3-tetrahydroxydihydrochalcone

Chemical Sources Association

Need This Item for Flavor/Food?: You can contact the Chemical Sources Association

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavoring agents
Recommendation for hesperetin dihydrochalcone usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 28
Click here to view publication 28
		average usual ppm	average maximum ppm
baked goods:		5.00000	10.00000
beverages(nonalcoholic):		1.50000	10.00000
beverages(alcoholic):		1.50000	10.00000
breakfast cereal:		5.00000	10.00000
cheese:		-	-
chewing gum:		5.00000	10.00000
condiments / relishes:		4.00000	10.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		3.00000	10.00000
fruit ices:		5.00000	10.00000
gelatins / puddings:		3.00000	10.00000
granulated sugar:		-	-
gravies:		2.00000	10.00000
hard candy:		2.00000	10.00000
imitation dairy:		-	-
instant coffee / tea:		1.50000	10.00000
jams / jellies:		-	-
meat products:		-	-
milk products:		2.00000	10.00000
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		3.00000	10.00000
processed vegetables:		2.00000	10.00000
reconstituted vegetables:		2.00000	10.00000
seasonings / flavors:		2.00000	10.00000
snack foods:		6.00000	10.00000
soft candy:		5.00000	10.00000
soups:		1.00000	10.00000
sugar substitutes:		-	-
sweet sauces:		4.00000	10.00000

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA GENetic TOXicology:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :147608

National Institute of Allergy and Infectious Diseases:Data

3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one

Chemidplus:0035400603

References:

	3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	147608
Pubchem (sid):	135102275

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB012806
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

3-(3-	hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
3-(3-	hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
1-	propanone, 3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)-

Articles:

PubMed:Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones.

PubMed:Degradation of neohesperidin dihydrochalcone by human intestinal bacteria.

PubMed:In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes.

Notes:

None found

hesperetin dihydrochalcone 1-propanone, 3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)-

Supplier Sponsors

Articles:

hesperetin dihydrochalcone
1-propanone, 3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)-