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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 433.70 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 362.00 °F. TCC ( 183.60 °C. ) (est)
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| logP (o/w): | 1.190 (est) |
| Soluble in: |
| | water, 1.229e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 3-O-methyl gallic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for 3-O-methyl gallic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzoic acid, 3,4-dihydroxy-5-methoxy- | | 3,4- | dihydroxy-5-methoxybenzoic acid | | 4,5- | dihydroxy-m-anisic acid | | 4,5- | dihydroxy-meta-anisic acid | | 3-O- | methylgallic acid |
Articles:
| PubMed:Studies on cytotoxic constituents from the leaves of Elaeagnus oldhamii Maxim. in non-small cell lung cancer A549 cells. |
| PubMed:Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid. |
| PubMed:Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer. |
| PubMed:The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. |
| PubMed:Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds. |
| PubMed:Methyl-3-O-methyl gallate and gallic acid from the leaves of Peltiphyllum peltatum: isolation and comparative antioxidant, prooxidant, and cytotoxic effects in neuronal cells. |
| PubMed:Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. |
| PubMed:A metabolite profiling approach to identify biomarkers of flavonoid intake in humans. |
| PubMed:Anti-ischemic activity and endothelium-dependent vasorelaxant effect of hydrolysable tannins from the leaves of Rhus coriaria (Sumac) in isolated rabbit heart and thoracic aorta. |
| PubMed:Synthesis of (-)-epicatechin 3-(3-O-methylgallate) and (+)-catechin 3-(3-O-methylgallate), and their anti-inflammatory activity. |
| PubMed:Identification of Cabernet Sauvignon anthocyanin gut microflora metabolites. |
| PubMed:Resonant two-photon ionization mass spectrometry of jet-cooled phenolic acids and polyphenols. |
| PubMed:Degradation of 3-O-methylgallate in Sphingomonas paucimobilis SYK-6 by pathways involving protocatechuate 4,5-dioxygenase. |
| PubMed:Biotransformation of gallic acid by Beauveria sulfurescens ATCC 7159. |
| PubMed:A tetrahydrofolate-dependent O-demethylase, LigM, is crucial for catabolism of vanillate and syringate in Sphingomonas paucimobilis SYK-6. |
| PubMed:[Studies on chemical constituents in fruits of Tibetan medicine Phyllanthus emblica]. |
| PubMed:Antioxidant activity of phenolic and related compounds: a density functional theory study on the O-H bond dissociation enthalpy. |
| PubMed:Characterization of the 3-O-methylgallate dioxygenase gene and evidence of multiple 3-O-methylgallate catabolic pathways in Sphingomonas paucimobilis SYK-6. |
| PubMed:A novel tetrahydrofolate-dependent O-demethylase gene is essential for growth of Sphingomonas paucimobilis SYK-6 with syringate. |
| PubMed:Gallic acid metabolites are markers of black tea intake in humans. |
| PubMed:Degradation of substituted mandelic acids by meta fission reactions. |
| PubMed:Interactions of natural phenols with macromolecules. |
| PubMed:Aerobic and Anaerobic Catabolism of Vanillic Acid and Some Other Methoxy-Aromatic Compounds by Pseudomonas sp. Strain PN-1. |
| PubMed:2-pyrone-4,6-dicarboxylic acid, a catabolite of gallic acids in Pseudomonas species. |
| PubMed:Bacterial degradation of 3,4,5-trimethoxycinnamic acid with production of methanol. |
| PubMed:Studies in vitro on the involvement of O-sulphate esters in the formation of O-methylated 3,4-dihydroxybenzoic acid by rat liver. |
| PubMed:Production of methanol from aromatic acids by Pseudomonas putida. |
| PubMed:Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases. |
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3D/inchi