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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 669.90 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 497.00 °F. TCC ( 258.60 °C. ) (est)
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| logP (o/w): | 2.550 (est) |
| Soluble in: |
| | water, 4972 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Norkanugin 98%
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| BOC Sciences |
| For experimental / research use only. |
| ROBINETIN >98%
Odor: characteristic Use: Robinetin is from the leaves of Robinia pseudacacia. It inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. It could lead to the occurrence of positive induced circular dichroism (ICD) bands in the near ultra-violet (UV)
antioxidant/antiradical/anti-mutagenesis/anti-promotion |
| Carbosynth |
| For experimental / research use only. |
| Robinetin
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| Coompo |
| For experimental / research use only. |
| Robinetin from Plants ≥96%
Odor: characteristic Use: Antioxidant and antiradical activities.
Anti-mutagenesis and anti-promotion.
Incorporation of robinetin molecules in the chiral environment of the β-CDxs strongly affects the electronic transitions of robinetin leading to the occurrence of positive induced circular dichroism (ICD) bands in the near ultra-violet (UV) region. Molecular mechanics calculations show that the inclusion complex with the chromone ring inserted into the β-CDx cavity is most favorable, in agreement with our spectroscopic data. |
| ExtraSynthese |
| For experimental / research use only. |
| Robinetin (HPLC) ≥99%
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Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for robinetin usage levels up to: | | | not for fragrance use.
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| Recommendation for robinetin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)- | | 4H-1- | benzopyran-4-one, 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)- (9CI) | | 5- | deoxymyricetin | | 3,7- | dihydroxy-2-(3,4,5-trihydroxy-phenyl)-chromen-4-one | | 3,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-benzopyrone | | 3,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one | | 3,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one | | 3,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one | | | flavone, 3,3',4',5',7-pentahydroxy- | | 5- | hydroxyfisetin | | | norkanugin | | 3,3',4',5',7- | pentahydroxyflavone |
Articles:
| PubMed:Phenolic composition of vinegars over an accelerated aging process using different wood species (acacia, cherry, chestnut, and oak): effect of wood toasting. |
| PubMed:Polyphenols in red wine aged in acacia (Robinia pseudoacacia) and oak (Quercus petraea) wood barrels. |
| PubMed:Polyphenolic profile as a useful tool to identify the wood used in wine aging. |
| PubMed:Effect of toasting intensity at cooperage on phenolic compounds in acacia (Robinia pseudoacacia) heartwood. |
| PubMed:Binding of the bioflavonoid robinetin with model membranes and hemoglobin: Inhibition of lipid peroxidation and protein glycosylation. |
| PubMed:Effect of beta-cyclodextrin nanocavity confinement on the photophysics of robinetin. |
| PubMed:An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers. |
| PubMed:Antimicrobial activity of flavonoids. |
| PubMed:Allelopathic potential of Robinia pseudo-acacia L. |
| PubMed:Effects of selected flavonoids and carotenoids on drug accumulation and apoptosis induction in multidrug-resistant colon cancer cells expressing MDR1/LRP. |
| PubMed:Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. |
| PubMed:Kinetic study of flavonoid reactions with stable radicals. |
| PubMed:Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102. |
| PubMed:Quercetin-induced apoptosis in colorectal tumor cells: possible role of EGF receptor signaling. |
| PubMed:Inhibition of mitochondrial respiration and cyanide-stimulated generation of reactive oxygen species by selected flavonoids. |
| PubMed:Protective effects of phenolic compounds on CCl4-induced toxicity in isolated rat hepatocytes. |
| PubMed:Superoxide scavenging properties of flavonoids in a non-enzymic system. |
| PubMed:Effect of plant flavonoids on microsome catalyzed reactions of aflatoxin B1 leading to activation and DNA adduct formation. |
| PubMed:Modulation by plant flavonoids and related phenolics of microsome catalyzed adduct formation between benzo[a]pyrene and DNA. |
| PubMed:Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. |
| PubMed:Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. |
| PubMed:Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. |
| PubMed:Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test: activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources. |
| PubMed:Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro. |
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3D/inchi