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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 732.40 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 537.00 °F. TCC ( 280.40 °C. ) (est)
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| logP (o/w): | 2.230 (est) |
| Soluble in: |
| | water, 2234 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for quercetagetin usage levels up to: | | | not for fragrance use.
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| Recommendation for quercetagetin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy- (9CI) | | 2-(3,4- | dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyrone | | 2-(3,4- | dihydroxyphenyl)-3,5,6,7-tetrahydroxychromen-4-one | | | flavone, 3,3',4',5,6,7-hexahydroxy- (8CI) | | 3,3',4',5,6,7- | hexahydroxyflavone | | 3,5,6,7,3',4'- | hexahydroxyflavone |
Articles:
| PubMed:eNOS-JNK1-AR signaling pathway mediates deltamethrin-induced germ cells apoptosis in testes of adult rats. |
| PubMed:Plant-Derived Flavones as Inhibitors of Aurora B Kinase and Their Quantitative Structure-Activity Relationships. |
| PubMed:Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study. |
| PubMed:Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention. |
| PubMed:A novel copigment of quercetagetin for stabilization of grape skin anthocyanins. |
| PubMed:A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia. |
| PubMed:Quercetagetin inhibits macrophage-derived chemokine in HaCaT human keratinocytes via the regulation of signal transducer and activator of transcription 1, suppressor of cytokine signalling 1 and transforming growth factor-β1. |
| PubMed:New thiophene and flavonoid from Tagetes minuta leaves growing in Saudi Arabia. |
| PubMed:Appraisal of biological activities and identification of phenolic compound of African marigold (Tagetes erecta) flower extract. |
| PubMed:Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads. |
| PubMed:Anti-Inflammatory Effect of Quercetagetin, an Active Component of Immature Citrus unshiu, in HaCaT Human Keratinocytes. |
| PubMed:Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol. |
| PubMed:Structural and functional analysis of the natural JNK1 inhibitor quercetagetin. |
| PubMed:Eight flavonoids and their potential as inhibitors of human cytomegalovirus replication. |
| PubMed:Influences of four different light-emitting diode lights on flowering and polyphenol variations in the leaves of chrysanthemum (Chrysanthemum morifolium). |
| PubMed:Inhibition of Pim-1 attenuates the proliferation and migration in nasopharyngeal carcinoma cells. |
| PubMed:Isolation of a new phlorotannin, a potent inhibitor of carbohydrate-hydrolyzing enzymes, from the brown alga Sargassum patens. |
| PubMed:HPLC-ESIMS(n) profiling, isolation, structural elucidation, and evaluation of the antioxidant potential of phenolics from Paepalanthus geniculatus. |
| PubMed:Antioxidant and cytotoxic flavonols from Calotropis procera. |
| PubMed:ISOLATION OF FIVE BIOACTIVE COMPONENTS FROM EUPATORIUM ADENOPHORUM SPRENG USING STEPWISE ELUTION BY HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY. |
| PubMed:Investigation into the antioxidant activity and chemical composition of alcoholic extracts from defatted marigold (Tagetes erecta L.) residue. |
| PubMed:Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. |
| PubMed:Use of countercurrent chromatography during isolation of 6-hydroxyluteolin-7-O-β-glucoside, a major antioxidant of Athrixia phylicoides. |
| PubMed:Activation of a non-genomic Pim-1/Bad-Pser75 module is required for an efficient pro-survival effect of Bcl-xL induced by androgen in LNCaP cells. |
| PubMed:The membrane transport of flavonoids from Crossostephium chinense across the Caco-2 monolayer. |
| PubMed:Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. |
| PubMed:The flavonoids luteolin and quercetagetin inhibit lipoteichoic acid actions on H9c2 cardiomyocytes. |
| PubMed:Antioxidant effects of Glechoma hederacea as a food additive. |
| PubMed:[Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense]. |
| PubMed:[Effects of chemical constituents of Crossostephium chinense on insulin secretion in rat islets in vitro]. |
| PubMed:Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation. |
| PubMed:Free radical scavengers and antioxidants from Tagetes mendocina. |
| PubMed:Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase. |
| PubMed:Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases. |
| PubMed:The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts. |
| PubMed:Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells. |
| PubMed:Structure-activity relationship of flavonoids for inhibition of epidermal growth factor-induced transformation of JB6 Cl 41 cells. |
| PubMed:Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. |
| PubMed:Determination of polymethoxylated flavones in peels of selected Jamaican and Mexican citrus (Citrus spp.) cultivars by high-performance liquid chromatography. |
| PubMed:[Studies on the flavonoids from whole herbs of Seriphidium terrae-albae]. |
| PubMed:Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida). |
| PubMed:Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima. |
| PubMed:Identification of radical scavenging compounds in Rhaponticum carthamoides by means of LC-DAD-SPE-NMR. |
| PubMed:Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels. |
| PubMed:Kinetic study of flavonoid reactions with stable radicals. |
| PubMed:G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). |
| PubMed:Variations in lipophilic and vacuolar flavonoids among European Pulicaria species. |
| PubMed:Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis. |
| PubMed:The role of lipophilic and polar flavonoids in the classification of temperate members of the Anthemideae. |
| PubMed:Geographical variation in the surface flavonoids of Pulicaria dysenterica. |
| PubMed:The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. |
| PubMed:Protective effect of flavonoids on endothelial cells against linoleic acid hydroperoxide-induced toxicity. |
| PubMed:Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion. |
| PubMed:Inhibition of tomato bushy stunt virus infection using a quercetagetin flavonoid isolated from Centaurea rupestris L. |
| PubMed:Antimicrobial activity of flavonoids from leaves of Tagetes minuta. |
| PubMed:HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching. |
| PubMed:A biologically active lipophilic flavonol from Tanacetum parthenium. |
| PubMed:Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils. |
| PubMed:Cytotoxic terpenoids and flavonoids from Artemisia annua. |
| PubMed:Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice. |
| PubMed:New Flavonoid Glycosides from Arnicae Flos DAB 91. |
| PubMed:Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives. |
| PubMed:Inhibition of rat lens aldose reductase by quercetagetin and patuletin. |
| PubMed:Anti-inflammatory activity and inhibition of arachidonic acid metabolism by flavonoids. |
| PubMed:Mechanisms of inhibition of various cellular DNA and RNA polymerases by several flavonoids. |
| PubMed:Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. |
| PubMed:Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs. |
| PubMed:C18 solid-phase isolation and high-performance liquid chromatography/ultraviolet diode array determination of fully methoxylated flavones in citrus juices. |
| PubMed:Screening of the influence of flavonoids on lipoxygenase and cyclooxygenase activity, as well as on nonenzymic lipid oxidation. |
| PubMed:Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study. |
| PubMed:The flavonoids of Parthenium L. |
| PubMed:Flavonols: pigments responsible for ultraviolet absorption in nectar guide of flower. |
| PubMed:Quercetagetin 3,6-dimethyl ether. |
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3D/inchi