EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

DL-mannitol
hexahydroxyhexane

Supplier Sponsors

Name:hexane-1,2,3,4,5,6-hexol
CAS Number: 87-78-5Picture of molecule3D/inchi
Other(deleted CASRN):133-43-7
ECHA EINECS - REACH Pre-Reg:201-770-2
FDA UNII: 3OWL53L36A
Nikkaji Web:J64.765I
XlogP3:-3.10 (est)
Molecular Weight:182.17278000
Formula:C6 H14 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:DL-mannitol
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Mannitol 98%
BOC Sciences
For experimental / research use only.
DL-Mannitol >98%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-man TDLo 5714 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Nephron. Vol. 45, Pg. 233, 1987.

intravenous-rat LD50 25800 uL/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
indirect food additives: adhesives and components of coatings
Recommendation for DL-mannitol usage levels up to:
 not for fragrance use.
 
Recommendation for DL-mannitol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):87-78-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :453
National Institute of Allergy and Infectious Diseases:Data
hexane-1,2,3,4,5,6-hexol
Chemidplus:0000087785
 
References:
 hexane-1,2,3,4,5,6-hexol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:87-78-5
Pubchem (cid):453
Pubchem (sid):135034800
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00392
HMDB (The Human Metabolome Database):HMDB00765
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 hexahydroxyhexane
 hexane-1,2,3,4,5,6-hexol
 mannidex 16700
 

Articles:

PubMed:Quantification of Water-Soluble Metabolites in Medicinal Mushrooms Using Proton NMR Spectroscopy.
PubMed:Taste Masked Orally Disintegrating Pellets of Antihistaminic and Mucolytic Drug: Formulation, Characterization, and In Vivo Studies in Human.
PubMed:Species diversity, community dynamics, and metabolite kinetics of the microbiota associated with traditional ecuadorian spontaneous cocoa bean fermentations.
PubMed:Rational development of taste masked oral liquids guided by an electronic tongue.
PubMed:Characterization of Chinese liquor starter, "Daqu", by flavor type with 1H NMR-based nontargeted analysis.
PubMed:Physiological, biochemical and molecular changes occurring during olive development and ripening.
PubMed:Lactobacillus reuteri CRL 1100 as starter culture for wheat dough fermentation.
PubMed:Characterization of the antioxidant activity of sugars and polyhydric alcohols in fish oil emulsions.
PubMed:Diversity of Geotrichum candidum strains isolated from traditional cheesemaking fabrications in France.
PubMed:Physicochemical Characteristics of Selected Sweet Cherry Cultivars.
PubMed:The acquired control of ingestive behavior in the rat by flavor-associated postingestional stimulation.
 
Notes:
None found
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