EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

tartronic acid
propanedioic acid, hydroxy- (9CI)

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Name:2-hydroxypropanedioic acid
CAS Number: 80-69-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:201-301-1
FDA UNII: 34T0025E0L
Nikkaji Web:J4.253F
Beilstein Number:1209791
XlogP3-AA:-1.10 (est)
Molecular Weight:120.06088000
Formula:C3 H4 O5
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
TARTRONIC ACID MP 156-158deg dec.
For experimental / research use only.
Tartronic Acid ≥97.0%
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for tartronic acid usage levels up to:
 not for fragrance use.
Recommendation for tartronic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :45
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-hydroxypropanedioic acid
 2-hydroxypropanedioic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):45
Pubchem (cas):80-69-3
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
Golm Metabolome Database:Search
KEGG (GenomeNet):C02287
HMDB (The Human Metabolome Database):HMDB35227
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 potato plant
Search Trop Picture
2-hydroxypropane dioic acid
2-hydroxypropanedioic acid
 propanedioic acid, hydroxy- (9CI)


PubMed:Jones oxidation of glycerol catalysed by small gold clusters.
PubMed:The preparation of large surface area lanthanum based perovskite supports for AuPt nanoparticles: tuning the glycerol oxidation reaction pathway by switching the perovskite B site.
PubMed:Identification of hydroxy- and keto-dicarboxylic acids in remote marine aerosols using gas chromatography/quadruple and time-of-flight mass spectrometry.
PubMed:Urinary metabolite profiling provides potential differentiation to explore the mechanisms of adjuvant-induced arthritis in rats.
PubMed:Protective Effects of Tinospora cordifolia on Hepatic and Gastrointestinal Toxicity Induced by Chronic and Moderate Alcoholism.
PubMed:Organics Substantially Reduce HO2 Uptake onto Aerosols Containing Transition Metal ions.
PubMed:Phosphofructokinase and malate dehydrogenase participate in the in vitro maturation of porcine oocytes.
PubMed:Photo-redox reactions of dicarboxylates and α-hydroxydicarboxylates at the surface of Fe(III)(hydr)oxides followed with in situ ATR-FTIR spectroscopy.
PubMed:The coordination chemistry of tartronic acid with copper: magnetic studies of a quasi-equilateral tricopper triangle.
PubMed:Investigation of the degradation of cresols in the treatments with ozone.
PubMed:Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control.
PubMed:Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.
PubMed:Recognition of (2S)-aminomalonyl-acyl carrier protein (ACP) and (2R)-hydroxymalonyl-ACP by acyltransferases in zwittermicin A biosynthesis.
PubMed:Reactions of iodomalonic acid, diiodomalonic acid, and other organics in the Briggs-Rauscher oscillating system.
PubMed:Oxidation of glycerol by 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) in the presence of laccase.
PubMed:A dynamic kinetic asymmetric transformation in the alpha-hydroxylation of racemic malonates and its application to biologically active molecules.
PubMed:Monitoring the acetohydroxy acid synthase reaction and related carboligations by circular dichroism spectroscopy.
PubMed:2-Pyridone-tartronic acid (1/1), 3-hydroxypyridinium hydrogen tartronate and 4-hydroxypyridinium hydrogen tartronate.
PubMed:Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid.
PubMed:Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data.
PubMed:Substrate and cofactor binding to fluorescently labeled cytoplasmic malate dehydrogenase.
PubMed:Synthesis, conformational studies, and investigations on the estrogen receptor binding of [R/S-1-(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]platinum(II) complexes.
PubMed:Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
PubMed:Chromatographic properties of the ion-exclusion column IonPac ICE-AS6 and application in environmental analysis. Part I: Chromatographic properties.
PubMed:Tartronates: a new generation of drugs affecting bone metabolism.
PubMed:New aromatic inhibitors of EPSP synthase incorporating hydroxymalonates as novel 3-phosphate replacements.
PubMed:Transient-state kinetic analysis of the oxidative decarboxylation of D-malate catalyzed by tartrate dehydrogenase.
PubMed:Triiodothyronine treatment increases substrate cycling between pyruvate carboxylase and malic enzyme in perfused rat liver.
PubMed:Hydroxymalonate inhibits lactate uptake by the rabbit hindlimb.
PubMed:Desaturation of polyunsaturated fatty acids in Mucor circinelloides and the involvement of a novel membrane-bound malic enzyme.
PubMed:Kinetic mechanism of the cytosolic malic enzyme from human breast cancer cell line.
PubMed:Pyruvate carboxylation prevents the decline in contractile function of rat hearts oxidizing acetoacetate.
PubMed:Effect of the intestinal flora on the urinary organic acid profile of rats ingesting a chemically simplified diet.
PubMed:Fluorescence studies with malate dehydrogenase from Bradyrhizobium japonicum 3I1B-143 bacteroids: a two-tryptophan containing protein.
PubMed:Kinetic formulations for the reduction of ketomalonate by lactate dehydrogenase.
PubMed:[Antilithogenic action of dehydroxymaleic, ketomalonic (mesoxalic) and tartronic acids in relation to experimental lithiasis in rats].
PubMed:Reversible dissociation of the catalytically active subunits of pigeon liver malic enzyme.
PubMed:Polymers for biodegradable medical devices. III. Polymerization and copolymerization of cyclic derivatives of tartronic acid.
PubMed:Inhibition by hydroxymalonate of malate dependent biosynthesis of progesterone in the mitochondrial fraction of human term placenta.
PubMed:Binary and ternary complexes of malate dehydrogenase with substrates and substrate analogs.
PubMed:Some kinetic characteristics of immobilized protomers and native dimers of mitochondrial malate dehydrogenase: an examination of the enzyme mechanism.
PubMed:Kinetic mechanism in the direction of oxidative decarboxylation for NAD-malic enzyme from Ascaris suum.
PubMed:A malic Acid permease in isolated vacuoles of a crassulacean Acid metabolism plant.
PubMed:The disposition of citric acid cycle intermediates by isolated rat heart mitochondria.
PubMed:A new chemical synthesis of D-tartronic acid semialdehyde phosphate and D-glyceric acid 2-phosphate.
PubMed:The quantitative determination of tartronic acid (hydroxymalonic acid) in urine and tissues.
PubMed:Inhibition of aerobic glycolysis in Yoshida ascites hepatoma by tartronic acid.
PubMed:Formation of arabinose, ribulose and tartronic acid from 2-keto-D-gluconic acid.
PubMed:Formation of 2-keto-D-gluconic acid, 5-keto-D-gluconic acid, and tartronic acid by Acetobacter species.
PubMed:The effect of tartronic acid on abnormal fat formation from carbohydrate.
PubMed:[Not Available].
Tartronic acid or 2-hydroxymalonic acid is a dicarboxylic acid with the structural formula of HOOCCH(OH)COOH. (Wikipedia)
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