EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

ethyl hydroxyethyl cellulose
cellulose ethyl 2-hydroxyethyl ether

Supplier Sponsors

CAS Number: 9004-58-4
Other(deleted CASRN):37226-58-7
Formula:C2 H6 O2.x-C2 H6 O.x-unspecified
Category:emulsifiers, stabilizers, thickeners
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Additive: Ethyl Hydroxyethyl Cellulose
GSFA Codex: Ethyl hydroxyethyl cellulose (467)
DG SANTE Food Contact Materials:ethylhydroxyethylcellulose
Physical Properties:
Appearance:pale yellow to grayish powder (est)
Assay: 94.00 to 100.00
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: binding agents
emulsion stabilisers
film formers
surfactant - emulsifying
viscosity controlling agents
Akzo Nobel
Bermocoll EHEC
Akzo Nobel
Bermocoll HM-EHEC
BOC Sciences
For experimental / research use only.
Cellulose ether 95%
For experimental / research use only.
Ethyl Hydroxyethyl Cellulose
Penta International
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
emulsifiers, stabilizers, thickeners
Recommendation for ethyl hydroxyethyl cellulose usage levels up to:
 not for fragrance use.
Recommendation for ethyl hydroxyethyl cellulose flavor usage levels up to:
 not for flavor use.
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):9004-58-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
Canada Domestic Sub. List:9004-58-4
Pubchem (sid):135020742
Other Information:
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
FAO:Ethyl hydroxyethyl cellulose
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 cellulose ethyl 2-hydroxyethyl ether
 cellulose ethyl hydroxyethyl ether
 ethyl-2-hydroxyethyl cellulose


PubMed:Polymer coated mucoadhesive liposomes intended for the management of xerostomia.
PubMed:Optical devices for the detection of cyanide in water based on ethyl(hydroxyethyl)cellulose functionalized with perichromic dyes.
PubMed:Polymer coated liposomes for use in the oral cavity - a study of the in vitro toxicity, effect on cell permeability and interaction with mucin.
PubMed:An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells.
PubMed:Self-association of sodium deoxycholate with EHEC cellulose cooperatively induced by sodium dodecanoate.
PubMed:Optical chemosensor for the detection of cyanide in water based on ethyl(hydroxyethyl)cellulose functionalized with Brooker's merocyanine.
PubMed:In vitro cytotoxicity of a thermoresponsive gel system combining ethyl(hydroxyethyl) cellulose and lysine-based surfactants.
PubMed:Aggregation of modified celluloses in aqueous solution: transition from methylcellulose to hydroxypropylmethylcellulose solution properties induced by a low-molecular-weight oxyethylene additive.
PubMed:Thermoresponsive hydrogels with low toxicity from mixtures of ethyl(hydroxyethyl) cellulose and arginine-based surfactants.
PubMed:Temperature responsive surface layers of modified celluloses.
PubMed:Use of cellulose derivatives on gold surfaces for reduced nonspecific adsorption of immunoglobulin G.
PubMed:Bi-layer formation of imidazole-modified ethyl(hydroxyethyl)cellulose at a hydrophobic surface as monitored by QCM-D.
PubMed:Effects of polymer additives on the crystallization of hydrates: a molecular-level modulation.
PubMed:Adsorption of cellulose derivatives on flat gold surfaces and on spherical gold particles.
PubMed:Influence of the functionalization pattern of ethyl cellulose on the interactions with polystyrene latex particles in aqueous mixtures.
PubMed:Adsorption behavior and cross-linking of EHEC and HM-EHEC at hydrophilic and hydrophobic modified surfaces monitored by SPR and QCM-D.
PubMed:Dispersed lipid liquid crystalline phases stabilized by a hydrophobically modified cellulose.
PubMed:Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats.
PubMed:Electrochemical control of the interactions of polymers and redox-active surfactants.
PubMed:Influence of counterion on the interaction of dodecyl sulfates and cellulose ethers.
PubMed:Influence of added particles on the phase behavior of polymer solutions. Analysis by mean-field lattice theory.
PubMed:Mechanisms of ethyl(hydroxyethyl) cellulose-solid interaction: influence of hydrophobic modification.
PubMed:Gels of hydrophobically modified ethyl(hydroxyethyl) cellulose cross-linked by amylose: effects of hydrophobe architecture.
PubMed:Added surfactant can change the phase behavior of aqueous polymer-particle mixtures.
PubMed:Water adsorption kinetics and contact angles of pharmaceutical powders.
PubMed:Rheological characterization of photochemical changes of ethyl(hydroxyethyl)cellulose dissolved in water in the presence of an ionic surfactant and a photosensitizer.
PubMed:Size and structure characterization of ethylhydroxyethyl cellulose by the combination of field-flow fractionation with other techniques. Investigation of ultralarge components.
PubMed:Initial characterization of ethyl(hydroxyethyl) cellulose using enzymic degradation and chromatographic methods.
PubMed:Molecular mass distribution analysis of ethyl(hydroxyethyl)cellulose by size-exclusion chromatography with dual light-scattering and refractometric detection.
PubMed:Ultrahigh molar mass component detected in ethylhydroxyethyl cellulose by asymmetrical flow field-flow fractionation coupled to multiangle light scattering.
PubMed:Prevention of adhesions by surfactants and cellulose derivatives in mice.
PubMed:Nonionic Cellulose Ethers as Potential Drug Delivery Systems for Periodontal Anesthesia.
PubMed:Adsorption of Ethyl(hydroxyethyl)cellulose onto Silica Particles: The Role of Surface Chemistry and Temperature.
PubMed:Amphiphilic association of ibuprofen and two nonionic cellulose derivatives in aqueous solution.
PubMed:Thermodynamics of Interaction between Some Cellulose Ethers and SDS by Titration Microcalorimetry.
PubMed:Surface activity and concentration dependent intestinal permeability in the rat.
PubMed:Polymers that reduce intraperitoneal adhesion formation.
PubMed:An NMR Self-Diffusion Investigation of Aggregation Phenomena in Solutions of Ethyl(hydroxyethyl)cellulose.
PubMed:Aqueous Solutions of Ethyl (Hydroxyethyl) Cellulose and Hydrophobic Modified Ethyl (Hydroxyethyl) Cellulose Polymer: Dynamic Surface Tension Measurements
PubMed:Bacterial translocation and intestinal capillary permeability following major liver resection in the rat.
PubMed:Effects of a water-soluble ethylhydroxyethyl cellulose on gut physiology, bacteriology, and bacterial translocation in acute liver failure.
PubMed:Water-soluble ethylhydroxyethyl cellulose: a new agent against bacterial translocation from the gut after major liver resection.
PubMed:The effect of liquid fibre on gastric emptying in the rat and humans and the distribution of small intestinal contents in the rat.
PubMed:Surface modification of intravenous catheters to reduce local tissue reactions.
PubMed:Objective and subjective efficacy evaluation of various polymer-based saliva substitutes.
PubMed:Water-soluble ethylhydroxyethyl cellulose prevents bacterial translocation induced by major liver resection in the rat.
PubMed:Modulation of bacterial binding to salivary pellicle by treatment with hydrophilizing compounds.
None found
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