EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

quercetin 3-O-b-D-galactopyranoside

Supplier Sponsors

CAS Number: 482-36-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-580-6
Nikkaji Web:J12.400A
Beilstein Number:5784795
XlogP3-AA:0.40 (est)
Molecular Weight:464.38080000
Formula:C21 H20 O12
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food additive
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 530 Extract of Apocynum venetum leaves View - notice PDF
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 872.63 °C. @ 760.00 mm Hg (est)
Flash Point: 585.00 °F. TCC ( 307.50 °C. ) (est)
logP (o/w): -0.111 (est)
Soluble in:
 water, 2.782e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Alfa Biotechnology
For experimental / research use only.
Hyperoside 98%
BOC Sciences
For experimental / research use only.
Hyperin 0.985
Odor: characteristic
Use: Hyperin isolated from the herb of Hypericum perforatum L. It maybe as a candidate therapeutic agent for the treatment of vascular inflammatory and occlusive vascular diseases, inhibiting HMGB1 signaling pathway and activating Nur77 receptor. neuro-protective effect; anti-inflammatory and antioxidative effects;
Changsha Organic Herb
Hawthorn Berry Extract
For experimental / research use only.
Hyperoside from Plants ≥96%
Odor: characteristic
Use: As an important bioactive compound, hyperoside has been documented to possess antiviral activity, antinociceptive activity, anti-inflammatory activity, cardio-protective, hepato-protective and gastricmucosal—protective effects. A bioactive constituent of apple peels with potent antioxidant and antiproliferative activities. It can have a protective antioxidant effect on cultured PC12 cells.
For experimental / research use only.
Hyperoside (HPLC) ≥98%
Santa Cruz Biotechnology
For experimental / research use only.
Quercetin 3-D-galactoside ≥98%
For experimental / research use only.
Hyperoside primary pharmaceutical reference standard
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
food additive
Recommendation for hyperoside usage levels up to:
 not for fragrance use.
Recommendation for hyperoside flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281643
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:DJ3009200 for cas# 482-36-0
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281643
Pubchem (sid):135030293
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C10073
HMDB (The Human Metabolome Database):HMDB30775
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
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4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(b-D-galactopyranosyloxy)-5,7-dihydroxy-
2-(3,4-dihydroxyphenyl)-3-(beta-dextro-galactopyranosyl oxy)-5,7-dihydroxy-4H-1-benzopyran-4-one
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl b-D-galactopyranoside
 quercetin 3-b-D-galactopyranoside
 quercetin 3-D-galactoside
 quercetin 3-O-b-D-galactopyranoside


PubMed:Modeling of the total antioxidant capacity of rooibos (Aspalathus linearis) tea infusions from chromatographic fingerprints and identification of potential antioxidant markers.
PubMed:Purification and characterization of flavonoids from the leaves of Zanthoxylum bungeanum and correlation between their structure and antioxidant activity.
PubMed:Phytochemical profiles and antioxidant and antimicrobial activities of the leaves of Zanthoxylum bungeanum.
PubMed:Ionic liquid-based one-step micellar extraction of multiclass polar compounds from hawthorn fruits by ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.
PubMed:Flavonol glycosides and other phenolic compounds in buds and leaves of different varieties of black currant (Ribes nigrum L.) and changes during growing season.
PubMed:Hyperoside and anthocyanin content of ten different pomegranate cultivars.
PubMed:Quantification of individual phenolic compounds' contribution to antioxidant capacity in apple: a novel analytical tool based on liquid chromatography with diode array, electrochemical, and charged aerosol detection.
PubMed:Hyperoside downregulates the receptor for advanced glycation end products (RAGE) and promotes proliferation in ECV304 cells via the c-Jun N-terminal kinases (JNK) pathway following stimulation by advanced glycation end-products in vitro.
PubMed:Comparative analysis of Tunisian wild Crataegus azarolus (yellow azarole) and Crataegus monogyna (red azarole) leaf, fruit, and traditionally derived syrup: phenolic profiles and antioxidant and antimicrobial activities of the aqueous-acetone extracts.
PubMed:Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
PubMed:Determination of hyperin in seed of Cuscuta chinensis Lam. by enhanced chemiluminescence of CdTe quantum dots on calcein/K3Fe(CN)6 system.
PubMed:Potent α-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris.
PubMed:Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities.
PubMed:Development of a validated HPLC method for the simultaneous determination of flavonoids in Cuscuta chinensis Lam. by ultra-violet detection.
PubMed:Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Receptaculum Nelumbinis by RP-HPLC Coupled with Hierarchical Clustering Analysis.
PubMed:Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside.
PubMed:Variation in phenolic content and antioxidant activity of fermented rooibos herbal tea infusions: role of production season and quality grade.
PubMed:Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation.
PubMed:Hepatoprotection with a chloroform extract of Launaea procumbens against CCl4-induced injuries in rats.
PubMed:Assessment of flavonoids contents and in vitro antioxidant activity of Launaea procumbens.
PubMed:A review of the chemistry of the genus Crataegus.
PubMed:Chemical composition and hepatoprotective effects of polyphenol-rich extract from Houttuynia cordata tea.
PubMed:Between species diversity of Hypericum perforatum and H. maculatum by the content of bioactive compounds.
PubMed:Pretreatment with the total flavone glycosides of Flos Abelmoschus manihot and hyperoside prevents glomerular podocyte apoptosis in streptozotocin-induced diabetic nephropathy.
PubMed:Phenolic composition in different genotypes of Guabiju fruits (Myrcianthes pungens) and their potential as antioxidant and antichemotactic agents.
PubMed:Comparative analysis of the chemical composition and antioxidant activity of red (Psidium cattleianum) and yellow (Psidium cattleianum var. lucidum) strawberry guava fruit.
PubMed:Phenolic compounds in hawthorn (Crataegus grayana) fruits and leaves and changes during fruit ripening.
PubMed:Quantitative analysis of phenolic compounds in Chinese hawthorn (Crataegus spp.) fruits by high performance liquid chromatography-electrospray ionisation mass spectrometry.
PubMed:Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat.
PubMed:Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki.
PubMed:Edible neotropical blueberries: antioxidant and compositional fingerprint analysis.
PubMed:Extraction and identification of three major aldose reductase inhibitors from Artemisia montana.
PubMed:Consumption of polyphenol concentrate with dietary fructo-oligosaccharides enhances cecal metabolism of quercetin glycosides in rats.
PubMed:Highly variable contents of phenolics in St. John's Wort products affect their transport in the human intestinal Caco-2 cell model: pharmaceutical and biopharmaceutical rationale for product standardization.
PubMed:Synergetic effect and structure-activity relationship of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors from Crataegus pinnatifida Bge.
PubMed:Isolation and purification of three flavonoid glycosides from the leaves of Nelumbo nucifera (Lotus) by high-speed counter-current chromatography.
PubMed:Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low-density lipoprotein and accumulation of lipid in differentiated THP-1 cells.
PubMed:Anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract.
PubMed:Bioactive constituent production in St. John's Wort in vitro hairy roots. Regenerated plant lines.
PubMed:Effect of Albizia julibrissin water extracts on low-density lipoprotein oxidization.
PubMed:Phenolic compounds, organic acids profiles and antioxidative properties of beefsteak fungus (Fistulina hepatica).
PubMed:Quantification of the polyphenols and triterpene acids in chinese hawthorn fruit by high-performance liquid chromatography.
PubMed:Comparison of methods for the exhaustive extraction of hypericins, flavonoids, and hyperforin from Hypericum perforatum L.
PubMed:Approach to novel functional foods for stress control 5. Antioxidant activity profiles of antidepressant herbs and their active components.
PubMed:An improved method for the quantitation of flavonoids in Herba Leonuri by capillary electrophoresis.
PubMed:Inhibitors of the epidermal growth factor receptor in apple juice extract.
PubMed:Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection.
PubMed:Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata.
PubMed:Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro.
PubMed:The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides.
PubMed:Unfermented rooibos tea: quantitative characterization of flavonoids by HPLC-UV and determination of the total antioxidant activity.
PubMed:Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress.
Occurs widely in plants, e.g. in apple peel and Hypericum perforatum (St John's wort) Hyperoside is the 3-O-galactoside of quercetin. It is a medicinally active compound that can be isolated from Drosera rotundifolia, from the Stachys plant, from Prunella vulgaris, from Rumex acetosella and from St John's wort. (Wikipedia)
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