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vinyl hexanoate
hexanoic acid, ethenyl ester

Supplier Sponsors

CAS Number: 3050-69-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:221-265-0
FDA UNII: GW724Y19YV
Nikkaji Web:J7.671F
MDL:MFCD00048869
XlogP3-AA:2.50 (est)
Molecular Weight:142.19798000
Formula:C8 H14 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (IAUFC):3050-69-9 ; VINYL HEXOATE
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 168.61 °C. @ 760.00 mm Hg (est)
Vapor Pressure:1.606000 mmHg @ 25.00 °C. (est)
Flash Point: 121.00 °F. TCC ( 49.30 °C. ) (est)
logP (o/w): 2.667 (est)
Soluble in:
 water, 411.7 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
n-Caproic acid vinyl ester (stabilized with HQ)
Santa Cruz Biotechnology
For experimental / research use only.
Vinyl Hexanoate
TCI AMERICA
For experimental / research use only.
Vinyl Hexanoate (stabilized with MEHQ) >99.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for vinyl hexanoate usage levels up to:
 not for fragrance use.
 
Recommendation for vinyl hexanoate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :76451
National Institute of Allergy and Infectious Diseases:Data
ethenyl hexanoate
Chemidplus:0003050699
 
References:
 ethenyl hexanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):76451
Pubchem (sid):135034830
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2915.90.7090
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ethenyl hexanoate
 hexanoic acid ethenyl ester
 hexanoic acid, ethenyl ester
 hexanoic acid, vinyl ester
 vinyl caproate
 

Articles:

PubMed:Non-targeted and targeted analysis of wild toxic and edible mushrooms using gas chromatography-ion trap mass spectrometry.
PubMed:Cyclodextrin-centred star polymers synthesized via a combination of thiol-ene click and ring opening polymerization.
PubMed:Sugar ester synthesis by thermostable lipase from Streptomyces thermocarboxydus ME168.
PubMed:Integration of catalysis and analysis is the key: rapid and precise investigation of the catalytic asymmetric Gosteli-Claisen rearrangement.
PubMed:Synthesis and in vitro release of adriamycin from star-shaped poly(lactide-co-glycolide) nano- and microparticles.
PubMed:Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation.
PubMed:Characterization of electrospun core/shell poly(vinyl pyrrolidone)/poly(L-lactide-co-epsilon-caprolactone) fibrous membranes and their cytocompatibility in vitro.
PubMed:Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols.
PubMed:Survey of 2-ethylhexanoic acid in baby food.
PubMed:Hyperbranched poly(epsilon-caprolactone) as a nonmigrating alternative plasticizer for phthalates in flexible PVC.
PubMed:Nanoparticles of beta-cyclodextrin esters obtained by self-assembling of biotransesterified beta-cyclodextrins.
PubMed:Preparation and characterization of chitosan and trimethyl-chitosan-modified poly-(epsilon-caprolactone) nanoparticles as DNA carriers.
PubMed:Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
PubMed:Regioselective synthesis of kojic acid esters by Bacillus subtilis protease.
PubMed:Polycaprolactone-poly(ethylene glycol) multiblock copolymers as potential substitutes for di(ethylhexyl) phthalate in flexible poly(vinyl chloride) formulations.
PubMed:Stability of i.v. mycophenolate mofetil in 5% dextrose injection in polyvinyl chloride infusion bags.
PubMed:Efficient introduction of alkene functionality into proteins in vivo.
PubMed:Immunological properties of allergen chemically modified with synthetic copolymer of N-vinylpyrrolidone and maleic anhydride.
PubMed:Reactions of glutamate semialdehyde aminotransferase (glutamate-1-semialdehyde 2,1 aminomutase) with vinyl and acetylenic substrate analogues analysed by rapid scanning spectrophotometry.
PubMed:The level of GAD67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels.
PubMed:[Gamma-vinyl-GABA: first experiences in Italy. II].
PubMed:Vigabatrin as an anticonvulsant against pentylenetetrazol seizures.
PubMed:Effect of vigabatrin (GVG) on serotonin (5-HT) uptake and release of human platelets in vitro.
PubMed:Comparative study of the anticonvulsant effect of gamma-aminobutyric acid agonists in the feline kindling model of epilepsy.
PubMed:Norepinephrine turnover in the goldfish brain is modulated by sex steroids and GABA.
PubMed:Adjuvant vigabatrin in refractory epilepsy: a ceiling to effective dosage in individual patients?
PubMed:Gamma-vinyl GABA decreases voluntary alcohol consumption in alcohol-preferring AA rats.
PubMed:GABA stimulation of gonadotropin-II release in goldfish: involvement of GABAA receptors, dopamine, and sex steroids.
PubMed:Exposure of newborn infants to di-(2-ethylhexyl)-phthalate and 2-ethylhexanoic acid following exchange transfusion with polyvinylchloride catheters.
PubMed:Effects of single and repeated administration of vigabatrin on the performance of non-epileptic rats in a delayed non-matching to position task.
PubMed:The influence of thalamic GABA transmission on the susceptibility of adult rats to flurothyl induced seizures.
PubMed:Modulation of central cholinergic activity by GABA and serotonin: PET studies with 11C-benztropine in primates.
PubMed:GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus.
PubMed:[Gamma-vinyl-GABA: the first trials in Italy].
PubMed:Effects of increased gamma-aminobutyric acid levels on GAD67 protein and mRNA levels in rat cerebral cortex.
PubMed:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), and gamma-vinyl-gamma-aminobutyric acid (gamma-vinyl GABA) alter neurotransmitter concentrations in the nervous tissue of the goldfish (Carassius auratus) but not the cockroach (Periplaneta americana).
PubMed:Effects of an inhibitor of GABA-aminotransferase (gamma-vinyl-GABA) on the spatial navigation deficit induced by nicotinic blockade.
PubMed:Vigabatrin (gamma-vinyl-GABA): neuropathologic evaluation in five patients.
PubMed:Acute effects of gamma-vinyl GABA on the GABAergic system in rats as studied by microdialysis.
PubMed:Relative anticonvulsant effects of GABAmimetic and GABA modulatory agents.
PubMed:Characterization of phencyclidine-induced effects on neuropeptide Y systems in the rat caudate-putamen.
PubMed:Vigabatrin has an anxiolytic effect in the elevated plus-maze test of anxiety.
PubMed:GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography.
PubMed:Absence of cortical white matter changes in three patients undergoing long-term vigabatrin therapy.
PubMed:Gamma-vinyl GABA prevents hippocampal and substantia nigra reticulata damage in repetitive transient forebrain ischemia.
PubMed:Effects of an inhibitor of GABA-aminotransferase (gamma-vinyl-GABA) on the spatial navigation deficit induced by muscarinic blockade.
PubMed:Gamma-vinyl GABA (vigabatrin): relationship between dosage, plasma concentrations, platelet GABA-transaminase inhibition, and seizure reduction in epileptic children.
PubMed:Gamma-vinyl GABA (vigabatrin) in epilepsy: clinical, neurochemical, and neurophysiologic monitoring in epileptic patients.
PubMed:Passage of S(+) and R(-) gamma-vinyl-GABA across the human isolated perfused placenta.
PubMed:Gamma vinyl GABA in the treatment of levodopa-induced dyskinesias in Parkinson's disease.
PubMed:Pharmacology of vigabatrin.
PubMed:Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats.
PubMed:Elevated gamma-aminobutyric acid levels attenuate the metabolic response to bilateral ischemia.
PubMed:Effects of gamma-vinyl GABA (vigabatrin) on blood pressure and body weight of hypertensive and normotensive rats.
PubMed:Effect of vigabatrin on the electroencephalogram in rats.
PubMed:Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex.
PubMed:Gamma-vinyl GABA (vigabatrin): clinical experience in adult and adolescent patients with intractable epilepsy.
PubMed:Treatment of pediatric epilepsies with gamma-vinyl GABA (vigabatrin).
PubMed:Effects of high-dose gamma-vinyl GABA (vigabatrin) administration on visual and somatosensory evoked potentials in dogs.
PubMed:GABA and epilepsy: basic concepts from preclinical research.
PubMed:Effects of substantia nigra gamma-vinyl-GABA infusions on flurothyl seizures in adult rats.
PubMed:Relationship between platelet and brain GABA transaminase inhibition by single and multiple doses of vigabatrin in rats.
PubMed:Open, double-blind and long-term study of vigabatrin in chronic epilepsy.
PubMed:Effect of gamma-vinyl gamma-aminobutyric acid on the gamma-aminobutyric acid receptor-coupled chloride ion channel in vesicles from the brain of the rat.
PubMed:Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat.
PubMed:GABAergic regulation of striatal opioid gene expression.
PubMed:Is the anticonvulsant effect of substantia nigra infusion of gamma-vinyl-GABA (GVG) mediated by the GABAA receptor in rat pups?
PubMed:Clinical evaluation of gamma-vinyl-gamma-aminobutyric acid for control of epilepsy in dogs.
PubMed:Effects of vigabatrin (gamma-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.
PubMed:The effect of gamma-vinyl-GABA on the performance of nucleus basalis-lesioned rats in spatial navigation task.
PubMed:Administration of vigabatrin (gamma-vinyl-gamma-aminobutyric acid) affects the levels of both inhibitory and excitatory amino acids in rat cerebrospinal fluid.
PubMed:Aminoaciduria due to vinyl-GABA administration.
PubMed:Pharmacokinetics of the individual enantiomers of vigabatrin (gamma-vinyl GABA) in epileptic children.
PubMed:Neuropathology of a human hippocampus following long-term treatment with vigabatrin: lack of microvacuoles.
PubMed:Potentiation of gamma-vinyl GABA (vigabatrin) effects by glycine.
PubMed:Development of tolerance to the effects of vigabatrin (gamma-vinyl-GABA) on GABA release from rat cerebral cortex, spinal cord and retina.
PubMed:Comparison of transmitter amino acid levels in rat globus pallidus and neostriatum during hypoglycemia or after treatment with methionine sulfoximine or gamma-vinyl gamma-aminobutyric acid.
PubMed:Synthesis, brain uptake, and pharmacological properties of a glyceryl lipid containing GABA and the GABA-T inhibitor gamma-vinyl-GABA.
PubMed:Appearance of vigabatrin (gamma-vinyl-gamma-aminobutyric acid, 4-amino-hex-5-enoic acid) in screening tests and analyses for amino acids.
PubMed:4-aminobutyrate-2-ketoglutarate aminotransferase (GABA-T) in human hair follicle.
PubMed:GABA inhibits thyroid hormone secretion in the mouse.
PubMed:Baclofen and phaclofen modulate GABA release from slices of rat cerebral cortex and spinal cord but not from retina.
PubMed:Identification of a median thalamic system regulating seizures and arousal.
PubMed:Vigabatrin in the treatment of childhood epilepsies: a single-blind placebo-controlled study.
PubMed:Anticonvulsant and proconvulsant effects of inhibitors of GABA degradation in the amygdala-kindling model.
PubMed:Immunocytochemical evidence that vigabatrin in rats causes GABA accumulation in glial cells of the retina.
PubMed:Electrophysiologic effects of gamma-vinyl GABA and carbamazepine.
PubMed:Effect of gamma-vinyl GABA on interictal spikes and sharp waves in patients with intractable complex partial seizures.
PubMed:gamma Vinyl GABA: current role in the management of drug-resistant epilepsy.
PubMed:Long-term evaluation of vigabatrin (gamma vinyl GABA) in epilepsy.
PubMed:Effects of long-term vigabatrin on somatosensory-evoked potentials in epileptic patients.
PubMed:Specificity of vigabatrin for the GABAergic system in human epilepsy.
PubMed:The neuropathology of vigabatrin.
PubMed:Pharmacokinetic effects of vigabatrin on cerebrospinal fluid amino acids in humans.
PubMed:gamma Vinyl GABA (vigabatrin) in epilepsy: the international experience. Proceedings of a symposium. Cincinnati, Ohio, April 16, 1988.
PubMed:Cerebrospinal fluid GABA and seizure control with vigabatrin.
PubMed:Effects of vigabatrin and of GABA on myelinated rat cerebellar cultures: preliminary data.
PubMed:Vigabatrin in epilepsy in mentally retarded patients.
PubMed:Potential antidepressant properties of subchronic GABA transaminase inhibitors in the forced swimming test in mice.
PubMed:GABA in epilepsy: the pharmacologic basis.
PubMed:[Lactate dehydrogenase isoenzymes in radiation therapy of cancer patients].
PubMed:Levels of total gamma-aminobutyric acid (GABA), free GABA and homocarnosine in cerebrospinal fluid of epileptic patients before and during gamma-vinyl-GABA (vigabatrin) treatment.
PubMed:[Preparation and testing of polymer drugs. 4. Water-soluble polymer drugs with a base of vinylpyrrolidone-maleic acid anhydride-copolymers].
PubMed:Microinjections of GABA agonists into the amygdala complex attenuates kindled seizure expression in the rat.
PubMed:Effect of vigabatrin (gamma-vinyl GABA) on amino acid levels in CSF of epileptic patients.
PubMed:GABA inhibits sexual behaviour in female rats.
PubMed:Experimental studies and controlled clinical testing of valproate and vigabatrin.
PubMed:Importance of glutamine for gamma-aminobutyric acid synthesis in rat neostriatum in vivo.
PubMed:Localized increase of GABA levels in brain areas of the rat and inhibition of the plasma LH rise following orchidectomy.
PubMed:gamma-Vinyl GABA in endopiriform area suppresses kindled amygdala seizures.
PubMed:Inhibitory and excitatory amino acids in CSF of patients suffering from complex partial seizures during chronic treatment with gamma-vinyl GABA (vigabatrin).
PubMed:Comparison between pentobarbital- and muscimol-induced feeding in satiated sheep.
PubMed:Effect of ethanol on gamma-vinyl GABA-induced GABA accumulation in the substantia nigra and on synaptosomal GABA content in six rat brain regions.
PubMed:Effect of vigabatrin on epilepsy in mentally retarded patients: a 7-month follow-up study.
PubMed:Regulation of transmitter gamma-aminobutyric acid (GABA) synthesis and metabolism illustrated by the effect of gamma-vinyl GABA and hypoglycemia.
PubMed:A controlled trial of gamma-vinyl-GABA (vigabatrin) in drug-resistant epilepsy.
PubMed:Studies on gamma-vinyl-GABA in Kuopio, Finland.
PubMed:Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons.
PubMed:Inhibition of the enzyme, GABA-aminotransferase in human platelets by vigabatrin, a potential antiepileptic drug.
PubMed:Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission.
PubMed:Gamma-vinyl GABA: comparison of neurochemical and anticonvulsant effects in mice.
PubMed:Abundant GABAergic innervation of rat posterior pituitary revealed by inhibition of GABA-transaminase.
PubMed:Luteinizing hormone release induced by noradrenaline after administration of drugs that increase hypothalamic GABA levels.
PubMed:Effect of vigabatrin (gamma-vinyl-GABA) on visual, brainstem auditory and somatosensory evoked potentials in epileptic patients.
PubMed:GABA agonists in cebus monkeys with neuroleptic-induced persistent dyskinesias.
PubMed:Effect of gamma-vinyl GABA treatment on cholinergic and aminergic neurotransmission and on cyclic nucleotides in human complex partial epilepsy--a CSF study.
PubMed:Clinical and biochemical effects of gamma-vinyl Gaba in tardive dyskinesia.
PubMed:One to three day dose intervals during subchronic treatment of epileptic gerbils with gamma-vinyl GABA: anticonvulsant efficacy and alterations in regional brain GABA levels.
PubMed:Functional anatomy of pentylenetetrazol and electroshock seizures in the rat brainstem.
PubMed:Double-blind dose reduction study of vigabatrin in complex partial epilepsy.
PubMed:Topically applied aminocaproic acid concentrates in the aqueous humor of the rabbit in therapeutic levels.
PubMed:The effects of in vivo inactivation of GABA-transaminase and glutamic acid decarboxylase on levels of GABA in the rat retina.
PubMed:Blockade of pro-oestrus LH surge and ovulation by GABA increase in the rat locus coeruleus.
PubMed:Suppression of methionine sulfoximine seizures by intranigral gamma-vinyl GABA injection.
PubMed:The role of substantia nigra in the development of kindling: pharmacologic and lesion studies.
PubMed:Brain gamma-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment.
PubMed:Micro-vacuolation in rat brains after long term administration of GABA-transaminase inhibitors. Comparison of effects of ethanolamine-O-sulphate and vigabatrin.
PubMed:Somatostatin, beta-endorphin, and prolactin levels in human cerebrospinal fluid during the gamma-vinyl-GABA treatment of patients with complex partial epilepsy.
PubMed:Effect of microinjections of gamma-vinyl GABA or isoniazid into substantia nigra on the development of amygdala kindling in rats.
PubMed:Anticonvulsant effects of GABA elevation in the deep prepiriform cortex.
PubMed:A study of the effects of vigabatrin on the central nervous system and retina of Sprague Dawley and Lister-Hooded rats.
PubMed:Effects of the gamma-aminobutyrate transaminase inhibitors gabaculine and gamma-vinyl GABA on gamma-aminobutyric acid release from slices of rat cerebral cortex.
PubMed:Vigabatrin: no microvacuoles in a human brain.
PubMed:Anterior thalamic mediation of generalized pentylenetetrazol seizures.
PubMed:Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling.
PubMed:Anterior thalamus and substantia nigra: two distinct structures mediating experimental generalized seizures.
PubMed:Kinetics of the enantiomers of vigabatrin after an oral dose of the racemate or the active S-enantiomer.
PubMed:Stereoselective uptake of the GABA-transaminase inhibitors gamma-vinyl GABA and gamma-acetylenic GABA into neurons and astrocytes.
PubMed:Vigabatrin in the treatment of epilepsy: a double-blind, placebo-controlled study.
PubMed:A controlled study of oral vigabatrin (gamma-vinyl GABA) in patients with cerebellar ataxia.
PubMed:In vivo action of enzyme-activated irreversible inhibitors of glutamic acid decarboxylase and gamma-aminobutyric acid transaminase in retina vs. brain.
PubMed:Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes.
PubMed:Susceptibility to seizures produced by pilocarpine in rats after microinjection of isoniazid or gamma-vinyl-GABA into the substantia nigra.
PubMed:Double-blind, placebo-controlled study of vigabatrin (gamma-vinyl GABA) in drug-resistant epilepsy.
PubMed:Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
PubMed:Double-blind study of oral gamma-vinyl GABA in the treatment of dystonia.
PubMed:Gamma-vinyl-GABA injection in the locus coeruleus region of the rat. Effect on spontaneous behavior and stress responses.
PubMed:Blockade of the LH surge and ovulation by GABA-T inhibitory drugs that increase brain GABA levels in rats.
PubMed:Effect of gamma-vinyl GABA on human pattern evoked visual potentials.
PubMed:Effects of gamma-vinyl-GABA on the human electroencephalogram.
PubMed:Iron concentration reduced in ventral pallidum, globus pallidus, and substantia nigra by GABA-transaminase inhibitor, gamma-vinyl GABA.
PubMed:Long-term study of gamma-vinyl GABA in the treatment of epilepsy.
PubMed:Experimental febrile convulsions in epileptic chickens: the anticonvulsant effect of elevated gamma-aminobutyric acid concentrations.
PubMed:Gamma-vinyl-GABA treatment of tardive dyskinesia and other movement disorders.
PubMed:Diazepam antagonizes GABAmimetics in rats with spontaneous petit mal-like epilepsy.
PubMed:Modulation of action of kainic acid on the behavior of rats by p-chlorophenylalanine and by gaba-mimetic drugs. Biochemical correlation between behavior and treatments.
PubMed:Determination of amino acids by separation of their ion pairs with dodecyl sulphate.
PubMed:Subchronic administration of GABAergic agonists elevates [3H]GABA binding and produces tolerance in striatal dopamine catabolism.
PubMed:gamma-Vinyl GABA: a double-blind placebo-controlled trial in partial epilepsy.
PubMed:gamma-Aminobutyric acid decreases levels of messenger ribonucleic acid encoding prolactin in the rat pituitary.
PubMed:Localization in the brain of the inhibition by GABA of luteinizing hormone release that follows orchidectomy in rats.
PubMed:Gamma-vinyl GABA: a new antiepileptic drug.
PubMed:Gamma-vinyl GABA.
PubMed:High-performance liquid chromatographic resolution of enantiomers of gamma-vinyl-gamma-aminobutyric acid.
PubMed:Evidence implicating substantia nigra in regulation of kindled seizure threshold.
PubMed:GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy.
PubMed:Synergistic anticonvulsant effects of GABA-T inhibitors and glycine.
PubMed:gamma-vinyl GABA, and GABA and beta-alanine transamination.
PubMed:Assay of gamma-vinyl-gamma-aminobutyric acid (4-amino-hex-5-enoic acid) in plasma and urine by automatic amino acid analysis. Application to human pharmacokinetics.
PubMed:Omega-aminoaciduria induced by gamma-vinyl GABA.
PubMed:Binding of [3H]gamma-vinyl-GABA to GABA-transaminase in brain homogenates.
PubMed:Biochemical and clinical effects of gamma-vinyl GABA in patients with epilepsy.
PubMed:Double-blind study of gamma-vinyl GABA in patients with refractory epilepsy.
PubMed:Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
PubMed:The amplification of the anticonvulsant effect of vinyl GABA (4-aminohexenoic acid) by esters of glycine.
PubMed:[Gamma-vinyl GABA and tardive dyskinesia: a single-blind study versus placebo].
PubMed:Gabaergic modulation of mouse-killing in the rat.
PubMed:Gamma-vinyl GABA treatment of Huntington's disease.
PubMed:Role of the amygdala in development of hippocampal kindling in the rat.
PubMed:Cortical GABA turnover during bicuculline seizures in rats.
PubMed:Gamma-vinyl-GABA: a single-blind trial in patients with epilepsy.
PubMed:Determination of the R(-)- and S(+)-enantiomers of gamma-vinyl-gamma-aminobutyric acid in human body fluids by gas chromatography--mass spectrometry.
PubMed:Anticonvulsant action in mice with sound-induced seizures of the optical isomers of gamma-vinyl GABA.
PubMed:Effect of gamma-vinyl GABA in tardive dyskinesia.
PubMed:Abortive amygdaloid kindled seizures following microinjection of gamma-vinyl-GABA in the vicinity of substantia nigra in rats.
PubMed:Total GABA and homocarnosine in CSF as indices of brain GABA concentrations.
PubMed:Time course relation between neurotoxic effects of kainic acid on behaviour and brain GABA-levels. Protection by gamma-vinyl GABA.
PubMed:[Effects of gamma-vinyl GABA per os in 5 cases of hebephreno-catatonic schizophrenia].
PubMed:Chronic elevation of brain GABA by gamma-vinyl GABA treatment does not alter the sensitivity of GABAergic or dopaminergic receptors in rat CNS.
PubMed:Acute effects of sodium valproate and gamma-vinyl GABA on regional amino acid metabolism in the rat brain: incorporation of 2-[14C]glucose into amino acids.
PubMed:GABAergic influences on defensive fighting in rats.
PubMed:Effects of gamma-vinyl GABA on food intake of rats.
PubMed:Measurement of release of endogenous GABA and catabolites of [3H]GABA from synaptosomal preparations using ion-exchange chromatography.
PubMed:Effect of gamma-vinyl GABA in Friedreich's ataxia.
PubMed:Cardiovascular effects of GABA, GABA-aminotransferase inhibitors and valproic acid following systemic administration in rats, cats and dogs: pharmacological approach to localize the site of action.
PubMed:[Therapeutic trial of gamma-vinyl GABA, an inhibitor of GABA transaminase, in tardive dyskinesias induced by neuroleptics].
PubMed:Suppression by sodium valproate of gamma-vinyl GABA-induced facilitation of visual evoked potentials in rats.
PubMed:Effects of gamma-vinyl GABA.
PubMed:Intracerebral injection of gamma vinyl GABA: method for measuring rates of GABA synthesis in specific brain regions in vivo.
PubMed:Effects of gamma-acetylenic GABA and gamma-vinyl GABA on synaptosomal release and uptake of GABA.
PubMed:Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid).
PubMed:Effect of gamma-vinyl GABA on bicuculline-induced seizures.
PubMed:Effect of gamma-vinyl GABA alone or associated with diazepam on a conflict test in the rat.
PubMed:The influence of a GABA transaminase inhibitor, gamma-vinyl GABA, on voluntary morphine consumption in the rat.
PubMed:Effects of gamma-acetylenic GABA and gamma-vinyl GABA on electrically-induced spinal cord convulsions and on spinal cord GABA concentration.
PubMed:Increased CSF gamma-aminobutyric acid after treatment with gamma-vinyl GABA.
PubMed:The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo.
PubMed:The effect of gamma-vinyl GABA and gamma-acetylenic GABA on the concentration of homocarnosine in brain and CSF of the rat.
PubMed:Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition.
PubMed:Effects of intraventricular gamma-acetylenic-GABA on GABA concentrations, GABA-T and GAD in several areas of the chick brain.
PubMed:Effects of gamma-acetylenic GABA and gamma-vinyl GABA on metrazol-activated, and kindled seizures.
PubMed:Enzyme-induced inactivation of transminases by acetylenic and vinyl analogues of 4-aminobutyrate.
PubMed:Metabolic inhibitors and subcellular distribution of GABA.
PubMed:Protection by 4-amino-hex-5-enoic acid (gamma-vinyl GABA) and hypobaric hypoxia against kainic acid neurotoxicity.
PubMed:Effect of GABA-transminase inhibition on rectal temperature in mice.
PubMed:Comments on a proposed mechanism of formation of the "schizophrenic odor factor".
PubMed:[Atopic reaction of the dog to polymeric substances].
 
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