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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 384.00 to 385.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 539.00 °F. TCC ( 281.70 °C. ) (est)
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| logP (o/w): | 6.395 (est) |
| Soluble in: |
| | water, 0.02371 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for pinolenic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for pinolenic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | columbinic acid | | (5E,9E,12E)- | octadeca-5,9,12-trienoic acid | | (E)-5,9,12- | octadecatrienoic acid | | trans-5,9,12- | octadecatrienoic acid |
Articles:
| PubMed:Metabolic Conversion of C20 Polymethylene-Interrupted Polyunsaturated Fatty Acids to Essential Fatty Acids. |
| PubMed:PGE2 production is suppressed by chemically-synthesized Δ7-eicosatrienoic acid in macrophages through the competitive inhibition of COX-2. |
| PubMed:Synthesis of phytosteryl ester containing pinolenic acid in a solvent-free system using immobilized Candida rugosa lipase. |
| PubMed:Diet enriched with korean pine nut oil improves mitochondrial oxidative metabolism in skeletal muscle and brown adipose tissue in diet-induced obesity. |
| PubMed:Synthesis of monoacylglycerol containing pinolenic acid via stepwise esterification using a cold active lipase. |
| PubMed:Lipase-catalyzed production of pinolenic acid concentrate from pine nut oil using a recirculating packed bed reactor. |
| PubMed:[Pine mouth syndrome: a global problem]. |
| PubMed:Effects of heat and ultraviolet radiation on the oxidative stability of pine nut oil supplemented with carnosic acid. |
| PubMed:Lipase-catalysed production of triacylglycerols enriched in pinolenic acid at the sn-2 position from pine nut oil. |
| PubMed:Effects of postharvest treatments on fruit quality of sweet pepper at low temperature. |
| PubMed:Enrichment of pinolenic acid at the sn-2 position of triacylglycerol molecules through lipase-catalyzed reaction. |
| PubMed:Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production. |
| PubMed:Uptake and incorporation of pinolenic acid reduces n-6 polyunsaturated fatty acid and downstream prostaglandin formation in murine macrophage. |
| PubMed:A front-end desaturase from Chlamydomonas reinhardtii produces pinolenic and coniferonic acids by omega13 desaturation in methylotrophic yeast and tobacco. |
| PubMed:Selective increase in pinolenic acid (all-cis-5,9,12-18:3) in Korean pine nut oil by crystallization and its effect on LDL-receptor activity. |
| PubMed:Abietoid seed fatty acid compositions--a review of the genera Abies, Cedrus, Hesperopeuce, Keteleeria, Pseudolarix, and Tsuga and preliminary inferences on the taxonomy of Pinaceae. |
| PubMed:An unusual desaturase in Aquilegia vulgaris. |
| PubMed:General characteristics of Pinus spp. seed fatty acid compositions, and importance of delta5-olefinic acids in the taxonomy and phylogeny of the genus. |
| PubMed:Non-methylene-interrupted polyunsaturated fatty acids: effective substitute for arachidonate of phosphatidylinositol. |
| PubMed:Identification of Delta5-desaturase from Mortierella alpina by heterologous expression in Bakers' yeast and canola. |
| PubMed:Methylene-interrupted double bond in polyunsaturated fatty acid is an essential structure for metabolism by the fatty acid chain elongation system of rat liver. |
| PubMed:Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. |
| PubMed:Octadecatrienoic acids as the substrates for the key enzymes in glycerolipid biosynthesis and fatty acid oxidation in rat liver. |
| PubMed:Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. |
| PubMed:Barrier function regulates epidermal lipid and DNA synthesis. |
| PubMed:Antagonists and inhibitors of lipid mediators in experimental inflammation of the cornea. |
| PubMed:Epidermal HMG CoA reductase activity in essential fatty acid deficiency: barrier requirements rather than eicosanoid generation regulate cholesterol synthesis. |
| PubMed:[Regulation of the epidermal permeability barrier by lipids and hyperproliferation]. |
| PubMed:Modulation of immunogenic keratitis in rabbits by topical administration of poly-unsaturated fatty acids. |
| PubMed:Metabolism of 6,9,12-octadecatrienoic acid and 6,9,12,15-octadecatetraenoic acid by rat hepatocytes. |
| PubMed:Naturally occurring conjugated octadecatrienoic acids are strong inhibitors of prostaglandin biosynthesis. |
| PubMed:Effect of dietary columbinic acid on the fatty acid composition and physical membrane properties of different tissues of EFA-deficient rats. |
| PubMed:Essential fatty acid deficiency: a new look at an old problem. |
| PubMed:Effect of different acids with delta 9,12-dienoic structures on delta 9 desaturation activity in rat liver microsomes. |
| PubMed:Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes. |
| PubMed:Urinary excretion of arginine-vasopressin and prostaglandin E2 in essential fatty acid-deficient rats after oral supplementation with unsaturated fatty acid esters. |
| PubMed:A unique cardiac cytosolic acyltransferase with preferential selectivity for fatty acids that form cyclooxygenase/lipoxygenase metabolites and reverse essential fatty acid deficiency. |
| PubMed:Physiologic effects of columbinic acid and its metabolites on rat skin. |
| PubMed:Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. |
| PubMed:The metabolic transformations of columbinic acid and the effect of topical application of the major metabolites on rat skin. |
| PubMed:The non-eicosanoid functions of the essential fatty acids. |
| PubMed:Effect of fatty acids of omega 6 series on the biosynthesis of arachidonic acid in HTC cells. |
| PubMed:Effect of specific dietary fatty acids on lipogenesis in the livers and mammary glands of lactating mice. |
| PubMed:Effect of dietary 18-carbon fatty acids on growth of transplantable mammary adenocarcinomas in mice. |
| PubMed:Columbinic acid, a new type of essential fatty acid. |
| PubMed:The manipulation of the fatty acid composition of Dictyostelium discoideum and its effect on cell differentiation. |
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3D/inchi