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dehydroabietic acid
13-isopropylpodocarpa-8,11,13-trien-15-oic acid

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Name:1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
CAS Number: 1740-19-8Picture of molecule3D/inchi
Other(deleted CASRN):135577-73-0
ECHA EINECS - REACH Pre-Reg:217-102-8
FDA UNII: 0S5XP6S3AU
Nikkaji Web:J354.835J
Beilstein Number:2059290
MDL:MFCD09839012
XlogP3-AA:5.60 (est)
Molecular Weight:300.44156000
Formula:C20 H28 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (IAUFC):1740-19-8 ; DEHYDROABIETIC ACID
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 425.08 °C. @ 760.00 mm Hg (est)
Flash Point: 397.00 °F. TCC ( 202.50 °C. ) (est)
logP (o/w): 6.120 (est)
Soluble in:
 water, 2.412 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
(-)-Dehydroabietic Acid
Coompo
For experimental / research use only.
Dehydroabietic Acid from Plants ≥96%
Odor: characteristic
Use: Dehydroabietic acid derivatives have been reported to display antisecretory and antipepsin effect in animal models. 20 µg l-1 is close to the “minimum effective concentration” of Dehydroabietic acid to rainbow trout. Dehydroabietic acid (DAA) treatment decreased not only plasma glucose and insulin levels but also plasma triglyceride (TG) and hepatic TG levels. To examine the mechanism underlying the effects of DAA, the production of inflammatory cytokines was measured. It was shown that the DAA treatment suppressed the production of monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-alpha (TNFalpha) (proinflammatory cytokines) and increased that of adiponectin (an anti-inflammatory cytokine). As a result of the changes in the production of inflammatory cytokines caused by the DAA treatment, the accumulation of macrophages in adipose tissues was reduced. These results indicate that treatment with DAA improves the levels of plasma glucose, plasma insulin, plasma TG, and hepatic TG through the decrease in the macrophage infiltration into adipose tissues, suggesting that DAA is a useful food-derived compound for treating obesity-related diseases.
Foreverest Resources
Dehydroabietic Acid
Santa Cruz Biotechnology
For experimental / research use only.
Dehydroabietic Acid
Sigma-Aldrich: Sigma
For experimental / research use only.
Dehydroabietic Acid
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1710 mg/kg
BEHAVIORAL: ATAXIA AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Bulletin of Environmental Contamination and Toxicology. Vol. 18, Pg. 42, 1977.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dehydroabietic acid usage levels up to:
 not for fragrance use.
 
Recommendation for dehydroabietic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):1740-19-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :15618
National Institute of Allergy and Infectious Diseases:Data
1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
Chemidplus:0001740198
 
References:
 1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:1740-19-8
Pubchem (cid):15618
Pubchem (sid):134980372
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
KEGG (GenomeNet):C12078
HMDB (The Human Metabolome Database):Search
YMDB (Yeast Metabolome Database):YMDB02310
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 abieta-8,11,13-trien-18-oic acid
 abietic acid, dehydro-
1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methyl ethyl)-1-phenanthrene carboxylic acid
(1R-(1alpha,4abeta,10aalpha))-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethyl phenanthren-1-carboxylic acid
(1R-(1a,4Abeta,10aa))-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid
1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-
 podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-
13-isopropyl podocarpa-8,11,13-trien-15-oic acid
isopropyl podocarpa-8,11,13-trien-15-oic acid
7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-1-phenanthrenecarboxylic acid
(1R,4aS,10aS)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
13-isopropylpodocarpa-8,11,13-trien-15-oic acid
 

Articles:

PubMed:Synthesis and antiproliferative activity of some novel triazole derivatives from dehydroabietic acid.
PubMed:Synthesis and antitumor activities of novel dipeptide derivatives derived from dehydroabietic acid.
PubMed:Dehydroabietic acid (DHAA) alters metabolic enzyme activity and the effects of 17β-estradiol in rainbow trout (Oncorhynchus mykiss).
PubMed:Seasonal and spatial variation of organic tracers for biomass burning in PM1 aerosols from highly insolated urban areas.
PubMed:Useful catalytic enantioselective cationic double annulation reactions initiated at an internal π-bond: method and applications.
PubMed:Synthesis and biological evaluation of novel N-substituted 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential antimicrobial agents.
PubMed:Diaromatic sulphur-containing 'naphthenic' acids in process waters.
PubMed:Synthesis and antitumor activities of novel thiourea α-aminophosphonates from dehydroabietic acid.
PubMed:Synthesis and antitumor activities of novel α-aminophosphonates dehydroabietic acid derivatives.
PubMed:Cytotoxic activities of amino acid-conjugate derivatives of abietane-type diterpenoids against human cancer cell lines.
PubMed:Acute toxicity of aromatic and non-aromatic fractions of naphthenic acids extracted from oil sands process-affected water to larval zebrafish.
PubMed:(+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro.
PubMed:Anticancer effects of a novel class rosin-derivatives with different mechanisms.
PubMed:[Determination of dehydroabietic acid and abietic acid in aqueous alkali extract of Liquidambaris Resina by HPLC].
PubMed:The atmospheric degradation reaction of dehydroabietic acid (DHAA) initiated by OH radicals and O3.
PubMed:A new dehydroabietic acid-based arylamine fluorescent probe: Synthesis, structure analysis and in vitro biodiagnose function.
PubMed:Resin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids.
PubMed:Variations in wood burning organic marker concentrations in the atmospheres of four European cities.
PubMed:[Antioxidant constituents from Smilax riparia].
PubMed:Isolation and estimation of the 'aromatic' naphthenic acid content of an oil sands process-affected water extract.
PubMed:Residential indoor PM2.5 in wood stove homes: follow-up of the Libby changeout program.
PubMed:Synthesis and antibacterial evaluation of New N-acylhydrazone derivatives from dehydroabietic acid.
PubMed:Kujigamberol, a new dinorlabdane diterpenoid isolated from 85million years old Kuji amber using a biotechnological assay.
PubMed:Molecular mechanism of pharmacological activation of BK channels.
PubMed:Characterization by gas chromatography-mass spectrometry of diterpenoid resinous materials in Roman-age amphorae from northern Greece.
PubMed:Differential patterns of dehydroabietic acid biotransformation by Nicotiana tabacum and Catharanthus roseus cells.
PubMed:[Diterpenoids from Chinese eaglewood].
PubMed:Evolution of diterpene metabolism: Sitka spruce CYP720B4 catalyzes multiple oxidations in resin acid biosynthesis of conifer defense against insects.
PubMed:Dehydroabietic acid activates peroxisome proliferator-activated receptor-γ and stimulates insulin-dependent glucose uptake into 3T3-L1 adipocytes.
PubMed:Determination of resin acids during production of wood pellets--a comparison of HPLC/ESI-MS with the GC/FID MDHS 83/2 method.
PubMed:Synthesis of cellulose dehydroabietate in ionic liquid [bmim]Br.
PubMed:Inhibition of nitric oxide production in RAW 264.7 macrophages by diterpenoids from Phellinus pini.
PubMed:Systematic phytochemical investigation of Abies spectabilis.
PubMed:Anaerobic treatability and biogas production potential of selected in-mill streams.
PubMed:Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives.
PubMed:Synthesis and antimicrobial activities of novel 1H-dibenzo[a,c]carbazoles from dehydroabietic acid.
PubMed:Disproportionated rosin dehydroabietic acid in neoprene surgical gloves.
PubMed:Estrogenic and anti-estrogenic effects of wood extractives present in pulp and paper mill effluents on rainbow trout.
PubMed:Syntheses, characterization and fluorescent properties of two series of dehydroabietic acid C-ring derivatives.
PubMed:The composition of the free fatty acids from Dendrolimus pini exuviae.
PubMed:Synthesis and biological evaluation of dehydroabietic acid derivatives.
PubMed:Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK-Ay mice.
PubMed:Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida.
PubMed:Cell transformation activities of abietic acid and dehydroabietic acid: safety assessment of possible contaminants in paper and paperboard for food contact use.
PubMed:Isolation and biological activities of neomyrrhaol and other terpenes from the resin of Commiphora myrrha.
PubMed:Highly enantioselective synthesis of gamma-nitro heteroaromatic ketones in a doubly stereocontrolled manner catalyzed by bifunctional thiourea catalysts based on dehydroabietic amine: a doubly stereocontrolled approach to pyrrolidine carboxylic acids.
PubMed:A review of biomarker compounds as source indicators and tracers for air pollution.
PubMed:Synthesis, structure analysis and cytotoxicity studies of novel unsymmetrically n,n'-substituted ureas from dehydroabietic Acid.
PubMed:Synthesis of dehydroabietic acid-modified chitosan and its drug release behavior.
PubMed:Evaluation of resin and fatty acid concentration levels by online sample enrichment followed by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS).
PubMed:Novel BK channel openers containing dehydroabietic acid skeleton: structure-activity relationship for peripheral substituents on ring C.
PubMed:Effects of unsaturation on film structure and friction of fatty acids in a model base oil.
PubMed:SPE and HPLC/UV of resin acids in colophonium-containing products.
PubMed:The green approaches for the synthesis of N-dehydroabietic alpha-aminophosphonates.
PubMed:[Isolation and identification of diterpenoids from Pinus koraiensis].
PubMed:Cancer chemopreventive activity of "rosin" constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test.
PubMed:Tape-stripping as a method for measuring dermal exposure to resin acids during wood pellet production.
PubMed:Exposure to wood dust, resin acids, and volatile organic compounds during production of wood pellets.
PubMed:13C and 1H NMR signal assignments of some new synthetic dehydroabietic acid derivatives.
PubMed:Dehydroabietic acid, a phytochemical, acts as ligand for PPARs in macrophages and adipocytes to regulate inflammation.
PubMed:Solvent control of optical resolution of 2-amino-1-phenylethanol using dehydroabietic acid.
PubMed:Effects of the wood extractives dehydroabietic acid and betulinol on reproductive physiology of zebrafish (Danio rerio)-a two-generation study.
PubMed:The use of primary hepatocytes from brown trout (Salmo trutta lacustris) and the fish cell lines RTH-149 and ZF-L for in vitro screening of (anti)estrogenic activity of wood extractives.
PubMed:Distinct roles for two CYP226 family cytochromes P450 in abietane diterpenoid catabolism by Burkholderia xenovorans LB400.
PubMed:Friction of fatty acids in nanometer-sized contacts of different adhesive strength.
PubMed:Spasmolytic effect of constituents from Lepechinia caulescens on rat uterus.
PubMed:Fourier transform infrared spectroscopy as a suitable technique in the study of the materials used in waterproofing of archaeological amphorae.
PubMed:[Characterization of the reaction products from pine gum catalytic disproportionation by gas chromatography/mass spectrometry].
PubMed:Fluorescence characteristics of some dehydroabietic acid-based arylamines.
PubMed:Activity of dehydroabietic acid derivatives against wood contaminant fungi.
PubMed:A large gene cluster in Burkholderia xenovorans encoding abietane diterpenoid catabolism.
PubMed:Dehydroabietic acid as a biomarker for exposure to colophony.
PubMed:Molecular detection and diversity of novel diterpenoid dioxygenase DitA1 genes from proteobacterial strains and soil samples.
PubMed:[Studies on diterpenes in needles of Pinus sylvestris].
PubMed:Fungal biotransformation products of dehydroabietic acid.
PubMed:Analysis of abietic acid and dehydroabietic acid in food samples by in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.
PubMed:Evaluation of the treatment efficiencies of paper mill whitewaters in terms of organic composition and toxicity.
PubMed:Efficient ortho-oxidation of phenol and synthesis of anti-MRSA and anti-VRE compound abietaquinone methide from dehydroabietic acid.
PubMed:Characterization of DitA3, the [Fe3S4] ferredoxin of an aromatic ring-hydroxylating dioxygenase from a diterpenoid-degrading microorganism.
PubMed:A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysis.
PubMed:Design, synthesis, and BK channel-opening activity of hexahydrodibenzazepinone derivatives.
PubMed:Degradingdehydroabietylisothiocyanate as a chiral derivatizing reagent for enantiomeric separations by capillary electrophoresis.
PubMed:Migration of dehydroabietic and abietic acids from paper and paperboard food packaging into food-simulating solvents and Tenax TA.
PubMed:Analysis of 525 samples to determine the usefulness of PCR amplification and sequencing of the 16S rRNA gene for diagnosis of bone and joint infections.
PubMed:Fluorescence study of dehydroabietic acid-based bipolar arylamine-quinoxalines.
PubMed:Improved aerobic biodegradation of abietic acid in ECF bleached kraft mill effluent due to biomass adaptation.
PubMed:Trypanocidal activity of oleoresin and terpenoids isolated from Pinus oocarpa.
PubMed:Combined effects of pulp and paper effluent, dehydroabietic acid, and hypoxia on swimming performance, metabolism, and hematology of rainbow trout.
PubMed:Safety assessment of paper and board food packaging: chemical analysis and genotoxicity of possible contaminants in packaging.
PubMed:Regio- and stereo-selective hydroxylation of abietic acid derivatives by Mucor circinelloides and Mortierella isabellina.
PubMed:Gastroprotective and cytotoxic effect of dehydroabietic acid derivatives.
PubMed:Primary organic pollutants in New Zealand urban aerosol in winter during high PM10 episodes.
PubMed:[Studies on chemical constituents from pine cone of Pinus armandii].
PubMed:Oxidative stress and genotoxic responses to resin acids in Mediterranean mussels.
PubMed:Effects of dehydroabietic acid and abietic acid on survival, reproduction, and growth of the crustacean Daphnia magna.
PubMed:Direct exposure electron ionization mass spectrometry and gas chromatography/mass spectrometry techniques to study organic coatings on archaeological amphorae.
PubMed:A cytochrome P450 involved in the metabolism of abietane diterpenoids by Pseudomonas abietaniphila BKME-9.
PubMed:Dermal exposure to terpenic resin acids in Swedish carpentry workshops and sawmills.
PubMed:Oxonitriles: multicomponent Grignard addition-alkylations.
PubMed:Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid.
PubMed:Anguilla anguilla L. plasma cortisol, lactate and glucose responses to abietic acid, dehydroabietic acid and retene.
PubMed:Dehydroabietic acid derivatives as a novel scaffold for large-conductance calcium-activated K+ channel openers.
PubMed:Tepidimonas aquatica sp. nov., a new slightly thermophilic beta-proteobacterium isolated from a hot water tank.
PubMed:Schlegelella thermodepolymerans gen. nov., sp. nov., a novel thermophilic bacterium that degrades poly(3-hydroxybutyrate-co-3-mercaptopropionate).
PubMed:Characterization of surface n-alkanes and fatty acids of the epiphytic lichen Xanthoria parietina, its photobiont a green alga Trebouxia sp., and its mycobiont, from the Jerusalem hills.
PubMed:Monitoring gene expression in mixed microbial communities by using DNA microarrays.
PubMed:Biomarker responses and resin acids in fish chronically exposed to effluents from a total chlorine-free pulp mill during regular production.
PubMed:Selected resin acids in effluent and receiving waters derived from a bleached and unbleached kraft pulp and paper mill.
PubMed:Potential antitumor-promoting diterpenes from the cones of Pinus luchuensis.
PubMed:Biotransformation, genotoxic, and histopathological effects of environmental contaminants in European eel (Anguilla anguilla L.).
PubMed:Juvenile sea bass liver biotransformation and erythrocytic genotoxic responses to pulp mill contaminants.
PubMed:Dehydroabietic acid, a major component of wood industry effluents, interferes with cellular energetics in rainbow trout hepatocytes.
PubMed:Juvenile sea bass liver biotransformation induction and erythrocytic genotoxic responses to resin acids.
PubMed:Structural effects on the bioactivity of dehydroabietic acid derivatives.
PubMed:Fate of resin acids in pulp mill secondary treatment systems.
PubMed:Bioaugmentation with the resin acid-degrading bacterium Zoogloea resiniphila DhA-35 to counteract pH stress in an aerated lagoon treating pulp and paper mill effluent.
PubMed:Oak moss extracts in the diagnosis of fragrance contact allergy.
PubMed:Molecular characterisation of organic material in air fine particles (PM10) using conventional and reactive pyrolysis-gas chromatography-mass spectrometry.
PubMed:Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.
PubMed:Characterization of tdt genes for the degradation of tricyclic diterpenes by Pseudomonas diterpeniphila A19-6a.
PubMed:Copper resinate: preparation, characterisation and study of degradation.
PubMed:Lipids as indicators of eutrophication in marine coastal sediments.
PubMed:Identification of a possible biomarker for colophony exposure.
PubMed:Detecting organic tracers from biomass burning in the atmosphere.
PubMed:Photoinduced toxicity of retene to Daphnia magna under enhanced UV-B radiation.
PubMed:Synthetic derivatives of abietic acid with radical scavenging activity.
PubMed:Reactivity of Trametes laccases with fatty and resin acids.
PubMed:Bioaugmentation with resin-acid-degrading bacteria enhances resin acid removal in sequencing batch reactors treating pulp mill effluents.
PubMed:Potential antitumor-promoting diterpenoids from the stem bark of Picea glehni.
PubMed:Influence of band 3 protein absence and skeletal structures on amphiphile- and Ca(2+)-induced shape alterations in erythrocytes: a study with lamprey (Lampetra fluviatilis), trout (Onchorhynchus mykiss) and human erythrocytes.
PubMed:Quantitation of the Population Size and Metabolic Activity of a Resin Acid Degrading Bacterium in Activated Sludge Using Slot-Blot Hybridization to Measure the rRNA:rDNA Ratio.
PubMed:Occurrence of the toxin dehydroabietic acid in Salmonella typhimurium.
PubMed:Recent advances in understanding resin acid biodegradation: microbial diversity and metabolism.
PubMed:Antimicrobial and antioxidant compounds in the nonvolatile fraction of expressed orange essential oil.
PubMed:Conjugation of 7-oxodehydroabietic acid to lysine, a haptenation mechanism for an oxidized resin acid with dermal sensitizing properties.
PubMed:Isolation and characterization of thermophilic bacteria capable of degrading dehydroabietic acid.
PubMed:Occurrence of Two Resin Acid-Degrading Bacteria and a Gene Encoding Resin Acid Biodegradation in Pulp and Paper Mill Effluent Biotreatment Systems Assayed by PCR.
PubMed:[Terpenoids and steroids from several euphorbiaceae and pinaceae plants].
PubMed:Antimicrobial activity of diterpene resin acid derivatives.
PubMed:A novel aromatic-ring-hydroxylating dioxygenase from the diterpenoid-degrading bacterium Pseudomonas abietaniphila BKME-9.
PubMed:An alternative inverse PCR (IPCR) method to amplify DNA sequences flanking Tn5 transposon insertions.
PubMed:Biochemical and genotoxic responses of adult eel (Anguilla anguilla L.) to resin acids and pulp mill effluent: laboratory and field experiments.
PubMed:Protective effects of an antiulcer agent, ecabet sodium on colorectal carcinogenesis in rodents.
PubMed:Induction of EROD activity and genotoxic effects by polycyclic aromatic hydrocarbons and resin acids on the juvenile eel (Anguilla anguilla L.).
PubMed:Detection of resin acid compounds in airborne particulate generated from rosin used as a soldering flux.
PubMed:Hydroxylation of dehydroabietic acid by Fusarium species.
PubMed:Bacterial metabolism of chlorinated dehydroabietic acids occurring in pulp and paper mill effluents.
PubMed:High-performance liquid chromatographic determination of dehydroabietic and abietic acids in traditional Chinese medications.
PubMed:Possible mechanism of increase in gastric mucosal PGE2 and PGI2 generation induced by ecabet sodium, a novel gastroprotective agent.
PubMed:Isolation and characterization of isopimaric acid-degrading bacteria from a sequencing batch reactor.
PubMed:Effects of a new antiulcer agent, ecabet sodium on a cutaneous tumorigenesis induced with 7,12-dimethylbenz(a)anthracene in mice.
PubMed:Rosin components identified in diapers.
PubMed:Toxic effects of some conifer resin acids and tea tree oil on human epithelial and fibroblast cells.
PubMed:Wood-derived estrogens: studies in vitro with breast cancer cell lines and in vivo in trout.
PubMed:The toxic and abortifacient effects of ponderosa pine.
PubMed:Environmentally friendly paper may increase risk of hand eczema in rosin-sensitive persons.
PubMed:Growth, induction, and substrate specificity of dehydroabietic acid-degrading bacteria isolated from a kraft mill effluent enrichment.
PubMed:Bacteria obtained from a sequencing batch reactor that are capable of growth on dehydroabietic acid.
PubMed:Antimicrobial screening of zinc in the absence or presence of oleoresins and various resin acids.
PubMed:Colophony in bindi adhesive.
PubMed:A method for 2D crystallization of soluble proteins at liquid-liquid interface.
PubMed:Excitatory actions of dehydroabietic acid on mammalian synaptosomes.
PubMed:Toxicity identification evaluations for the investigation of fish kills: a case study.
PubMed:Effects of dehydroabietic acid on the physical state of cytoskeletal proteins and the lipid bilayer of erythrocyte membranes.
PubMed:Inhibition of platelet aggregation by diterpene acids from Pinus massoniana resin.
PubMed:Contact allergy due to colophony. (IX). Sensitization studies with further products isolated after oxidative degradation of resin acids and colophony.
PubMed:Toxic effects of bleached and unbleached paper mill effluents in primary cultures of rainbow trout hepatocytes.
PubMed:Preparation of potential anti-inflammatory agents from dehydroabietic acid.
PubMed:Occupational asthma induced by tall oil in the rubber tyre industry.
PubMed:Rosin allergy: identification of a dehydroabietic acid peroxide with allergenic properties.
PubMed:Dehydroabietic acid, a major anionic contaminant of pulp mill effluent, reduces both active p-aminohippurate transport and passive membrane permeability in isolated renal membranes.
PubMed:Neutralizing effect of zinc oxide on dehydroabietic acid-induced toxicity on human polymorphonuclear leukocytes.
PubMed:Neutralizing effect of zinc oxide on dehydroabietic acid-induced toxicity on human polymorphonuclear leukocytes.
PubMed:Effects of dehydroabietic acid on the erythrocyte membrane.
PubMed:Antibacterial effects of zinc oxide, rosin, and resin acids with special reference to their interactions.
PubMed:Detection of rosin (colophony) components in technical products using an HPLC technique.
PubMed:Contact allergy due to colophony (VII). Sensitizing studies with oxidation products of abietic and related acids.
PubMed:Bioavailability of benzo(a)pyrene and dehydroabietic acid from a few lake waters containing varying dissolved organic carbon concentrations to Daphnia magna.
PubMed:Metabolites of (+)-dehydroabietic acid in rabbits.
PubMed:Antibacterial activity of rosin and resin acids in vitro.
PubMed:Dehydroabietic acid (DHAA) does not inhibit bilirubin conjugation in the liver of rainbow trout.
PubMed:Contact allergy to dehydroabietic acid derivatives isolated from Portuguese colophony.
PubMed:Hydrogenation reduces the allergenicity of colophony (rosin).
PubMed:Biotransformation of Dehydroabietic, Abietic, and Isopimaric Acids by Mortierella isabellina Immobilized in Polyurethane Foam.
PubMed:Contact allergy to colophony. Chemical identifications of allergens, sensitization experiments and clinical experiences.
PubMed:Effects of plasma proteins on the dehydroabietic acid-induced red cell breakdown.
PubMed:Effects of aquatic humus on accumulation and acute toxicity of some organic micropollutants.
PubMed:Changes of the liver UDP-glucuronosyltransferase activity in trout (Salmo gairdneri Rich.) acutely exposed to selected aquatic toxicants.
PubMed:Terpenoid biotransformation in mammals. IV Biotransformation of (+)-longifolene, (-)-caryophyllene, (-)-caryophyllene oxide, (-)-cyclocolorenone, (+)-nootkatone, (-)-elemol, (-)-abietic acid and (+)-dehydroabietic acid in rabbits.
PubMed:Subacute physiological effects of bleached kraft mill effluent (BKME) on the liver of trout, Salmo gairdneri.
PubMed:Antiulcer activity of dehydroabietic acid derivatives.
PubMed:Biotransformation of dehydroabietic acid with resting cell suspensions and calcium alginate-immobilized cells of Mortierella isabellina.
PubMed:Metabolic effects of dehydroabietic acid on rainbow trout erythrocytes.
PubMed:Effect of pH on acute toxicity of dehydroabietic acid and chlorinated dehydroabietic acid to fish and Daphnia.
PubMed:Influence of diterpene resin acids on feeding and growth of larch sawfly,Pristiphora erichsonii (Hartig).
PubMed:Seasonal changes in certain metabolic and haematologic responses of Salmo gairdneri acutely exposed to dehydroabietic acid (DHAA).
PubMed:Mutagenicity of resin acids identified in pulp and paper mill effluents using the Salmonella/mammalian-microsome assay.
PubMed:Toxicity studies on dehydroabietic acid.
PubMed:Allergic contact dermatitis to a salicyclic acid plaster.
PubMed:Conversion of dehydroabietic acid into a steroid skeleton: formation of the A-ring. III.
PubMed:Steroids and sex hormones. Transformation of dehydroabietic acid into 14-methyl-steroids. II. The synthesis of 3-oxo-17beta-acetoxy-14alpha-methyl-delta4-8alpha, 9beta, 10alpha, 13alpha-estrene.
PubMed:[Steroids and sexual hormones. 249. The transformation of dehydroabietic acid into 14 alpha-methylsteroids. I. The partial synthesis of 5-methoxy-17-oxo-14 alpha-methyl-delta(5,7,9,)-des-A-estratriene].
PubMed:[Microbial degradation of dehydroabietic acid].
PubMed:[Antiarrhythmic effect of the diethylaminoethylamide of dehydroabietic acid (substance E-25), quinidine and procaine amide in arrhythmia in anesthetized dogs, induced by K-strophanthin].
PubMed:[Comparison of the in situ effect of diethylaminoethylamide of dehydroabietic acid (substance E-25), quinidine and procaine on the fibrillation threshold of the heart in anesthetized cats].
PubMed:[PROTECTIVE EFFECT OF DIETHYLAMINOETHYLAMIDE OF DEHYDROABIETIC ACID (SUBSTANCE E-25) IN CACL2-INDUCED ARRHYTHMIAS IN RATS].
PubMed:Studies on abietic acid derivatives. II. Deisopropylation of dehydroabietic acid.
PubMed:Studies on abietic acid derivatives. I. Deisopropylation of dehydroabietic acid.
 
Notes:
major aquatic toxicant in effluent of pulp and paper mills.
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