|
Category:antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 571.42 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 402.00 °F. TCC ( 205.50 °C. ) (est)
|
| logP (o/w): | 3.113 (est) |
| Soluble in: |
| | water, 30.6 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Demethoxycurcumin 98%
|
| BOC Sciences |
| For experimental / research use only. |
| Demethoxycurcumin >98%
Odor: characteristic Use: Natural demethoxy curcuminoid. Anticancer, antiproliferative and antioxidant activity. Inhibits various signaling pathways including Wnt/a-catenin, AMPK and MAPK. |
| Coompo |
| For experimental / research use only. |
| Demethoxycurcumin from Plants ≥98%
Odor: characteristic Use: Different analogs of curcumin present in turmeric exhibit variable anti-inflammatory and anti-proliferative activities, which do not correlate with their ability to modulate the ROS status.
Antioxidant capacities of the extracts, as ascorbic acid equivalent (µmol/g) were in the order: curcumin > demethoxycurcumin > bisdemethoxycurcumin. In comparison with butylated hydroxyl toluene (BHT), at 100 ppm, the antioxidant activity, by linoleic acid peroxidation, was found to be highest with curcumin, followed by demethoxycurcumin and bisdemethoxycurcumin. |
| Glentham Life Sciences |
| Demethoxycurcumin
|
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Demethoxycurcumin
|
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Demethoxycurcumin ≥98% (HPLC)
|
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | antioxidants |
| Recommendation for (E,E)-demethoxycurcumin usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for (E,E)-demethoxycurcumin flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
| | (1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5469424 |
| Pubchem (sid): | 135104208 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | curcumin II | | (E,E)- | desmethoxycurcumin | | 1,6- | heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)- | | (1E,6E)-1-(4- | hydroxy-3-methoxy-phenyl)-7-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione | | (1E,6E)-1-(4- | hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione | | 1-(4- | hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1E,6E-heptadiene-3,5-dione | | (1E,6E)-1-(4- | hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione | | (1E,6E)-1-(4- | hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione | | (1E,6E)-1-(4- | hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione |
Articles:
| PubMed:Inhibitory Effect of Turmeric Curcuminoids on FLT3 Expression and Cell Cycle Arrest in the FLT3-Overexpressing EoL-1 Leukemic Cell Line. |
| PubMed:Demethoxycurcumin from Curcuma longa rhizome suppresses iNOS induction in an in vitro inflamed human intestinal mucosa model. |
| PubMed:Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer's disease Drosophila models. |
| PubMed:A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry. |
| PubMed:Comparative absorption of curcumin formulations. |
| PubMed:Determination of antiplasmodial activity and binding affinity of curcumin and demethoxycurcumin towards PfTrxR. |
| PubMed:Analysis of the anticancer activity of curcuminoids, thiotryptophan and 4-phenoxyphenol derivatives. |
| PubMed:Quick supramolecular solvent-based microextraction for quantification of low curcuminoid content in food. |
| PubMed:Optimization and validation of high-performance liquid chromatography method for individual curcuminoids in turmeric by heat-refluxed extraction. |
| PubMed:Inhibition of anthrax lethal factor by curcumin and chemically modified curcumin derivatives. |
| PubMed:Curcuminoid metabolism and its contribution to the pharmacological effects. |
| PubMed:Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells. |
| PubMed:Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids? |
| PubMed:The binding of Curcuma longa extract with bovine serum albumin monitored via time-resolved fluorescence. |
| PubMed:A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin, and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke. |
| PubMed:Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells. |
| PubMed:Preparation of monodisperse curcumin-imprinted polymer by precipitation polymerization and its application for the extraction of curcuminoids from Curcuma longa L. |
| PubMed:Quantification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin in rodent brain by UHPLC/ESI-Q-TOF-MS/MS after intra-nasal administration of curcuminoids loaded PNIPAM nanoparticles. |
| PubMed:Simultaneous determination of three Curcuminoids in Curcuma wenyujin Y.H.chen et C.Ling. by liquid chromatography-tandem mass spectrometry combined with pressurized liquid extraction. |
| PubMed:Simultaneous screening of four epidermal growth factor receptor antagonists from Curcuma longa via cell membrane chromatography online coupled with HPLC-MS. |
| PubMed:Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: an in vitro and in vivo study. |
| PubMed:Preparation and oral bioavailability study of curcuminoid-loaded microemulsion. |
| PubMed:Bioactivity of turmeric-derived curcuminoids and related metabolites in breast cancer. |
| PubMed:Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1. |
| PubMed:Development of a validated UPLC-qTOF-MS Method for the determination of curcuminoids and their pharmacokinetic study in mice. |
| PubMed:A novel approach to active compounds identification based on support vector regression model and mean impact value. |
| PubMed:Effects of curcumin and demethoxycurcumin on amyloid-β precursor and tau proteins through the internal ribosome entry sites: a potential therapeutic for Alzheimer's disease. |
| PubMed:Curcuminoids and resveratrol as anti-Alzheimer agents. |
| PubMed:Molecular docking studies on inhibition of Stat3 dimerization by curcumin natural derivatives and its conjugates with amino acids. |
| PubMed:Correlation between Chemical Composition of Curcuma domestica and Curcuma xanthorrhiza and Their Antioxidant Effect on Human Low-Density Lipoprotein Oxidation. |
| PubMed:Curcumin: from chemistry to chemistry-based functions. |
| PubMed:A reduced curcuminoid analog as a novel inducer of fetal hemoglobin. |
| PubMed:The cellular uptake and cytotoxic effect of curcuminoids on breast cancer cells. |
| PubMed:Anti-Acanthamoebic properties of resveratrol and demethoxycurcumin. |
| PubMed:Antioxidant properties of Mannich bases. |
| PubMed:Production of Curcuminoids in different in vitro organs of Curcuma longa. |
| PubMed:Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats. |
| PubMed:The in vitro protective effects of curcumin and demethoxycurcumin in Curcuma longa extract on advanced glycation end products-induced mesangial cell apoptosis and oxidative stress. |
| PubMed:Demethoxycurcumin modulates prostate cancer cell proliferation via AMPK-induced down-regulation of HSP70 and EGFR. |
| PubMed:Design, synthesis and biological activity of new polyenolic inhibitors of matrix metalloproteinases: a focus on chemically-modified curcumins. |
| PubMed:Forming of demethoxycurcumin nanocrystallite-chitosan nanocarrier for controlled low dose cellular release for inhibition of the migration of vascular smooth muscle cells. |
| PubMed:Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation. |
| PubMed:Isolation and identification of phase 1 metabolites of curcuminoids in rats. |
| PubMed:Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers. |
| PubMed:Evaluation of naturally occurring curcuminoids and related compounds against mosquito larvae. |
| PubMed:Curcumin--from molecule to biological function. |
| PubMed:Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice. |
| PubMed:Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells. |
| PubMed:Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff. |
| PubMed:Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. |
| PubMed:Revisiting curcumin chemistry part I: a new strategy for the synthesis of curcuminoids. |
| PubMed:Demethoxycurcumin Retards Cell Growth and Induces Apoptosis in Human Brain Malignant Glioma GBM 8401 Cells. |
| PubMed:Curcuminoids promote neurite outgrowth in PC12 cells through MAPK/ERK- and PKC-dependent pathways. |
| PubMed:Studies on curcumin and curcuminoids. XLVI. Photophysical properties of dimethoxycurcumin and bis-dehydroxycurcumin. |
| PubMed:Curcuminoid analogs inhibit nitric oxide production from LPS-activated microglial cells. |
| PubMed:Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice. |
| PubMed:Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. |
| PubMed:A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease. |
| PubMed:Phytochemical and cytotoxic investigations of Curcuma mangga rhizomes. |
| PubMed:Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines. |
| PubMed:Physiological and therapeutical roles of ginger and turmeric on endocrine functions. |
| PubMed:Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. |
| PubMed:Compounds isolated from Curcuma aromatica Salisb. inhibit human P450 enzymes. |
| PubMed:Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3. |
| PubMed:Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt. |
| PubMed:Anti-inflammatory mechanisms of compounds from Curcuma mangga rhizomes using RAW264.7 macrophage cells. |
| PubMed:Reactions of reactive oxygen species (ROS) with curcumin analogues: Structure-activity relationship. |
| PubMed:Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices. |
| PubMed:The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells. |
| PubMed:Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid. |
| PubMed:Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity. |
| PubMed:The inhibitory effect of turmeric curcuminoids on matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells. |
| PubMed:Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease. |
| PubMed:Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180. |
| PubMed:Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. |
| PubMed:Development of binding assays to screen ligands for Plasmodium falciparum thioredoxin and glutathione reductases by ultrafiltration and liquid chromatography/mass spectrometry. |
| PubMed:[Chemical constituents from Piper longum]. |
| PubMed:Inhibitory effects of curcuminoids on passive cutaneous anaphylaxis reaction and scratching behavior in mice. |
| PubMed:Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide. |
| PubMed:Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. |
| PubMed:Effects of Curcuma spp. on P-glycoprotein function. |
| PubMed:Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line. |
| PubMed:Comparison of extraction methods for the analysis of natural dyes in historical textiles by high-performance liquid chromatography. |
| PubMed:Optimized turmeric extracts have potent anti-amyloidogenic effects. |
| PubMed:Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis. |
| PubMed:Identification and characterization of multiple curcumin synthases from the herb Curcuma longa. |
| PubMed:Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. |
| PubMed:Curcumin derivatives: molecular basis of their anti-cancer activity. |
| PubMed:Direct analysis of curcumin in turmeric by DART-MS. |
| PubMed:New synthetic glucosyl-curcuminoids, and their (1)H and (13)C NMR characterization, from Curcuma longa L. |
| PubMed:Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells. |
| PubMed:Metabolite analysis in Curcuma domestica using various GC-MS and LC-MS separation and detection techniques. |
| PubMed:A simple HPLC-fluorescence method for quantitation of curcuminoids and its application to turmeric products. |
| PubMed:[Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin]. |
| PubMed:A simple 2-directional high-performance thin-layer chromatographic method for the simultaneous determination of curcumin, metanil yellow, and sudan dyes in turmeric, chili, and curry powders. |
| PubMed:Induction of antioxidant enzymes by curcumin and its analogues in human islets: implications in transplantation. |
| PubMed:[Fingerprint of Curcuma phaeocaulis by LC-MS]. |
| PubMed:Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. |
| PubMed:Demethoxycurcumin and its semisynthetic analogues as antitubercular agents. |
| PubMed:Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications. |
| PubMed:Standardization of the ayurvedic formulation Haridra Khanda using high-performance thin-layer chromatography-densitometry. |
| PubMed:Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. |
| PubMed:Comparison of inhibitory potency of three different curcuminoid pigments on nitric oxide and tumor necrosis factor production of rat primary microglia induced by lipopolysaccharide. |
| PubMed:Purification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin by high-speed countercurrent chromatography. |
| PubMed:Quantitation of curcuminoids in curcuma rhizome by near-infrared spectroscopic analysis. |
| PubMed:Qualitative and quantitative analysis of four species of Curcuma rhizomes using twice development thin layer chromatography. |
| PubMed:[Study on effect of demethoxycurcumin in Curcuma long on stability of curcumin]. |
| PubMed:Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA. |
| PubMed:Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. |
| PubMed:Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor. |
| PubMed:Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo. |
| PubMed:Molecularly imprinted poly (methacrylamide-co-methacrylic acid) composite membranes for recognition of curcumin. |
| PubMed:Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines. |
| PubMed:Separation and free radical-scavenging activity of major curcuminoids of Curcuma longa using HPTLC-DPPH method. |
| PubMed:Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis. |
| PubMed:Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats. |
| PubMed:Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells. |
| PubMed:Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. |
| PubMed:HPLC-photodiode array detection analysis of curcuminoids in Curcuma species indigenous to Indonesia. |
| PubMed:Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS. |
| PubMed:Formulation and characterization of curcuminoids loaded solid lipid nanoparticles. |
| PubMed:Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. |
| PubMed:Comparative study of copper(II)-curcumin complexes as superoxide dismutase mimics and free radical scavengers. |
| PubMed:Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. |
| PubMed:Biological evaluation of curcumin and related diarylheptanoids. |
| PubMed:Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection. |
| PubMed:Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin. |
| PubMed:Comparison of Anti-inflammatory Activities of Six Curcuma Rhizomes: A Possible Curcuminoid-independent Pathway Mediated by Curcuma phaeocaulis Extract. |
| PubMed:[Effect of three different curcumin pigmens on the prdiferation of vascular smooth muscle cells by ox-LDL and the expression of LDL-R]. |
| PubMed:Microemulsion electrokinetic chromatography for separation and analysis of curcuminoids in turmeric samples. |
| PubMed:Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome. |
| PubMed:Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver. |
| PubMed:Alpha-glucosidase inhibition of natural curcuminoids and curcumin analogs. |
| PubMed:Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin. |
| PubMed:Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. |
| PubMed:Elucidation of anti-allergic activities of curcumin-related compounds with a special reference to their anti-oxidative activities. |
| PubMed:A labdane diterpene glucoside from the rhizomes of Curcuma mangga. |
| PubMed:Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine. |
| PubMed:Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of alpha,beta-unsaturated carbonyl compounds. |
| PubMed:Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice. |
| PubMed:Antioxidative constituents of Etlingera elatior. |
| PubMed:Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice. |
| PubMed:Detection and quantitation of curcumin in mouse lung cell cultures by matrix-assisted laser desorption ionization time of flight mass spectrometry. |
| PubMed:Antitumour-promoting and cytotoxic constituents of etlingera elatior. |
| PubMed:Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. |
| PubMed:Inhibitory activity of diarylheptanoids on farnesyl protein transferase. |
| PubMed:Quantitative determination of curcuminoids in Curcuma rhizomes and rapid differentiation of Curcuma domestica Val. and Curcuma xanthorrhiza Roxb. by capillary electrophoresis. |
| PubMed:Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids. |
| PubMed:Protection of pancreatic beta-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes. |
| PubMed:Extraction of essential oil and pigments from Curcuma longa [L] by steam distillation and extraction with volatile solvents. |
| PubMed:Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food. |
| PubMed:In vitro peroxynitrite scavenging activity of diarylheptanoids from Curcuma longa. |
| PubMed:Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). |
| PubMed:Microarray-based analysis of anti-angiogenic activity of demethoxycurcumin on human umbilical vein endothelial cells: crucial involvement of the down-regulation of matrix metalloproteinase. |
| PubMed:Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. |
| PubMed:Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. |
| PubMed:Improved HPLC method for the determination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin. |
| PubMed:Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa. |
| PubMed:Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue. |
| PubMed:[Study on the characterizations of genus Curcuma plants on the strains of C. longa L. and C. aromatica Salisb preserved at Izu station of NIHS]. |
| PubMed:Antifungal activity of Curcuma longa grown in Thailand. |
| PubMed:Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. |
| PubMed:Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. |
| PubMed:Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes. |
| PubMed:Occurrence of orally administered curcuminoid as glucuronide and glucuronide/sulfate conjugates in rat plasma. |
| PubMed:Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa. |
| PubMed:A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa. |
| PubMed:Pro-oxidant, anti-oxidant and cleavage activities on DNA of curcumin and its derivatives demethoxycurcumin and bisdemethoxycurcumin. |
| PubMed:Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria. |
| PubMed:Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships. |
| PubMed:Inhibitory effects of curcumin on tumorigenesis in mice. |
| PubMed:Nitric oxide scavenging by curcuminoids. |
| PubMed:Free radical scavenging activity of curcuminoids. |
| PubMed:Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. |
| PubMed:Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro. |
| PubMed:Curcuminoids as potent inhibitors of lipid peroxidation. |
| PubMed:Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. |
| PubMed:Nematocidal activity of turmeric: synergistic action of curcuminoids. |
| PubMed:[Terpenoids and curcuminoids of the rhizoma of Curcuma xanthorrhiza Roxb]. |
| PubMed:Action of curcuminoids on the hemolysis and lipid peroxidation of mouse erythrocytes induced by hydrogen peroxide. |
| PubMed:[Separation and determination of curcuminoids in Curcuma longa L. and its preparation by HPLC]. |
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