| PubMed:Exserolides A-F, new isocoumarin derivatives from the plant endophytic fungus Exserohilum sp. |
| PubMed:Isocoumarins from American cockroach (Periplaneta americana) and their cytotoxic activities. |
| PubMed:A Convergent Total Synthesis of the Telomerase Inhibitor (±)-γ-Rubromycin. |
| PubMed:Two new secondary metabolites from Xylaria sp. cfcc 87468. |
| PubMed:Silica sulfuric acid: a reusable solid catalyst for one pot synthesis of densely substituted pyrrole-fused isocoumarins under solvent-free conditions. |
| PubMed:Gymnopalynes A and B, chloropropynyl-isocoumarin antibiotics from cultures of the basidiomycete Gymnopus sp. |
| PubMed:[Two novel isocoumarins from Erigeron breviscapus]. |
| PubMed:Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea. |
| PubMed:Ruthenium-catalyzed C-H activation/cyclization for the synthesis of phosphaisocoumarins. |
| PubMed:Tandem Michael addition/cyclization reaction of 2,3-allenoates with organozincs: facile synthesis of isocoumarins. |
| PubMed:One-pot tandem Hurtley-retro-Claisen-cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs. |
| PubMed:Br···O contacts and π-π stacking dominate the packing in methyl 4-bromo-3,5-dimethoxybenzoate. |
| PubMed:Hydrogen-bonded dimers in 3-amino-4-anilino-1H-isochromen-1-one and a hydrogen-bonded sheet in 3-amino-4-[methyl(phenyl)amino]-1H-isochromen-1-one. |
| PubMed:Three new glucosides from a cold-adapted fungal strain Mucor sp. |
| PubMed:A new antimicrobial and anticancer peptide producing by the marine deep sediment strain "Paenibacillus profundus" sp. nov. Sl 79. |
| PubMed:Sparstolonin B suppresses lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells. |
| PubMed:Isocoumarin derivatives and benzofurans from a sponge-derived Penicillium sp. fungus. |
| PubMed:Plant growth activities of aspyran, asperentin, and its analogues produced by the fungus Aspergillus sp. |
| PubMed:Paenibacillus profundus sp. nov., a deep sediment bacterium that produces isocoumarin and peptide antibiotics. |
| PubMed:Antimicrobial potential of deep surface sediment associated bacteria from the Sea of Japan. |
| PubMed:Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay. |
| PubMed:PJS, a novel isocoumarin with hexahydropyrimidine ring from Bacillus subtilis PJS. |
| PubMed:Synthesis and antibacterial evaluation of typharin analog: 6,8-dihydroxy-7-methyl-3-styryl-3,4-dihydroisocoumarin. |
| PubMed:Synthesis of isocoumarin derivatives by copper-catalyzed addition of o-halobenzoic acids to active internal alkynes. |
| PubMed:Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein. |
| PubMed:A 14-membered macrolide and isocoumarin derivatives from the cultured lichen mycobionts of Graphis vestitoides. |
| PubMed:Isolation, identification and antimicrobial activities of two secondary metabolites of Talaromyces verruculosus. |
| PubMed:Machilusmarin, a new neuroprotective isocoumarin dimer from the stems of Machilus ichangensis Rehd. et Wils. |
| PubMed:The antibacterial activity of compounds isolated from oakmoss against Legionella pneumophila and other Legionella spp. |
| PubMed:LC-MS/MS as a tool for identification of bioactive compounds in marine sponge Spongosorites halichondriodes (Dendy 1905). |
| PubMed:Cytotoxic constituents from the fungus Daldinia concentrica (Xylariaceae). |
| PubMed:Redirection of pigment biosynthesis to isocoumarins in Fusarium. |
| PubMed:Phthalide and isocoumarin derivatives produced by an Acremonium sp. isolated from a mangrove Rhizophora apiculata. |
| PubMed:Synthesis of isocoumarin derivatives via the copper-catalyzed tandem sequential cyclization of 2-halo-N-phenyl benzamides and acyclic 1,3-diketones. |
| PubMed:Synthesis of new bergenin derivatives as potent inhibitors of inflammatory mediators NO and TNF-α. |
| PubMed:Haworforbins A-C, new phenolics from Haworthia cymbiformis. |
| PubMed:Antiplasmodial activity of bacilosarcin A isolated from the octocoral-associated bacterium Bacillus sp. collected in Panama. |
| PubMed:Synthesis and biological evaluation of some novel 3,4-disubstituted isocoumarins. |
| PubMed:Assembly of 3-substituted isocoumarins via a CuI-catalyzed domino coupling/addition/deacylation process. |
| PubMed:An allosteric anti-hepsin antibody derived from a constrained phage display library. |
| PubMed:[Studies on metabolites from marine microorganism Aspergillus terreus collected from nature reserve region of mangrove]. |
| PubMed:Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes. |
| PubMed:Transcript and protein profiling analysis of OTA-induced cell death reveals the regulation of the toxicity response process in Arabidopsis thaliana. |
| PubMed:Absolute stereochemistry of novel isochromanone derivatives from Leptosphaeria sp. KTC 727. |
| PubMed:Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate. |
| PubMed:The influence of the fungal pathogen Mycocentrospora acerina on the proteome and polyacetylenes and 6-methoxymellein in organic and conventionally cultivated carrots (Daucus carota) during post harvest storage. |
| PubMed:Polyketides with antimicrobial activity from the solid culture of an endolichenic fungus Ulocladium sp. |
| PubMed:Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies. |
| PubMed:Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. |
| PubMed:Nematicidal activity of fervenulin isolated from a nematicidal actinomycete, Streptomyces sp. CMU-MH021, on Meloidogyne incognita. |
| PubMed:3,6,8-Trihy-droxy-3,4,5,7-tetra-methyl-3,4-dihydro-isocoumarin. |
| PubMed:Chemical constituents of a marine fungus, Arthrinium sacchari. |
| PubMed:Alternative spiroketalization methods toward purpuromycin: a diketone approach to prevent benzofuran formation. |
| PubMed:Alternative spiroketalization methods toward purpuromycin: a hemiketal conjugate addition strategy and use of an electron-rich isocoumarin precursor. |
| PubMed:Synthesis of 5-chloro-8-hydroxy-6-methoxy-3-pentylisocoumarin. |
| PubMed:Phenolic compounds from the cultured mycobionts of Graphis proserpens. |
| PubMed:Bioactive compounds from the scale insect pathogenic fungus Conoideocrella tenuis BCC 18627. |
| PubMed:Alkyne derivatives of isocoumarins as clickable activity-based probes for serine proteases. |
| PubMed:Bioactive isocoumarins from a terrestrial Streptomyces sp. ANK302. |
| PubMed:Toxic polyketides produced by Fusarium sp., an endophytic fungus isolated from Melia azedarach. |
| PubMed:Bireticulol, a bioactive isocoumarin dimer from Streptomyces sp. BCC24731. |
| PubMed:[Studies on the chemical constituents of the flowers of Bupleurum chinese]. |
| PubMed:Iodine-mediated solvent-controlled selective electrophilic cyclization and oxidative esterification of o-alkynyl aldehydes: an easy access to pyranoquinolines, pyranoquinolinones, and isocumarins. |
| PubMed:The structural basis for catalysis and substrate specificity of a rhomboid protease. |
| PubMed:Angiogenesis and chronic kidney disease. |
| PubMed:Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13. |
| PubMed:Antifungal properties of methanol extract and its active compounds from Brickellia rosmarinifolia Vent. |
| PubMed:Radical scavenging and angiotensin converting enzyme inhibitory activities of standardized extracts of Ficus racemosa stem bark. |
| PubMed:Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors. |
| PubMed:Phosphaisocoumarins as a new class of potent inhibitors for pancreatic cholesterol esterase. |
| PubMed:Studies on a chlorogenic acid-producing endophytic fungi isolated from Eucommia ulmoides Oliver. |
| PubMed:Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90. |
| PubMed:3-tert-Butyl-1H-isochromene-1-thione. |
| PubMed:Chemical characterization of Phoma pomorum isolated from Danish maize. |
| PubMed:Palladium-catalyzed aryl halide carbonylation-intramolecular O-enolate acylation: efficient isocoumarin synthesis, including the synthesis of thunberginol A. |
| PubMed:Solution-phase synthesis of a diverse isocoumarin library. |
| PubMed:Chemical Constituents of the Fruiting Body of Xylaria polymorpha. |
| PubMed:New bioactive compounds from Aloe hijazensis. |
| PubMed:Isocoumarin glucosides from the scale insect fungus Torrubiella tenuis BCC 12732. |
| PubMed:Four new compounds from Paeonia albiflora. |
| PubMed:Waste-free synthesis of condensed heterocyclic compounds by rhodium-catalyzed oxidative coupling of substituted arene or heteroarene carboxylic acids with alkynes. |
| PubMed:6,8-Dihydr-oxy-3-methyl-isocoumarin. |
| PubMed:3-(4-Fluoro-benz-yl)-1H-isochromene-1-thione. |
| PubMed:3-(3-Bromo-benz-yl)-1H-isochromen-1-one. |
| PubMed:New phytotoxic metabolites from Pestalotiopsis sp. HC02, a Fungus Residing in Chondracris rosee gut. |
| PubMed:Synthesis of 3-substituted isocoumarins and their inhibitory effects on degranulation of RBL-2H3 cells induced by antigen. |
| PubMed:Isolation and structure of whiskey polyphenols produced by oxidation of oak wood ellagitannins. |
| PubMed:Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. |
| PubMed:Isocoumarin-based inhibitors of pancreatic cholesterol esterase. |
| PubMed:In vitro leishmanicidal activity of 3-substituted isocoumarins: synthesis and structure activity relationship. |
| PubMed:3-(4-Methoxy-phen-yl)-1H-isochromen-1-one. |
| PubMed:3-(3-Fluoro-benz-yl)-1H-isochromen-1-one. |
| PubMed:2-[(4-Chloro-benz-yl)carbonyl-meth-yl]benzoic acid. |
| PubMed:3-[(R)-3,3-Dichloro-2-hydroxy-prop-yl]-8-hydr-oxy-6-meth-oxy-1H-isochromen-1-one. |
| PubMed:3-(3-Chloro-benz-yl)-1H-isochromen-1-one. |
| PubMed:Dihydroisocoumarin from Xyris pterygoblephara active against dermatophyte fungi. |
| PubMed:A new isocoumarin from Hypericum annulatum. |
| PubMed:Isocoumarin Derivatives from the Sea Squirt-derived Fungus Penicillium stoloniferum QY2-10 and the Halotolerant Fungus Penicillium notatum B-52. |
| PubMed:Molecular mechanisms of paclitaxel and NM-3 on human gastric cancer in a severe combined immune deficiency mice orthotopic implantation model. |
| PubMed:Structure elucidation of compounds extracted from the Chinese medicinal plant Patrinia heterophylla. |
| PubMed:Rhodium- and iridium-catalyzed oxidative coupling of benzoic acids with alkynes via regioselective C-H bond cleavage. |
| PubMed:Synergistic effect of oxymatrine and angiogenesis inhibitor NM-3 on modulating apoptosis in human gastric cancer cells. |
| PubMed:An efficient waste-free oxidative coupling via regioselective C-H bond cleavage: Rh/Cu-catalyzed reaction of benzoic acids with alkynes and acrylates under air. |
| PubMed:Effect of 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid in combination with carboplatin on gastric carcinoma growth in vivo. |
| PubMed:Palladium-catalyzed coupling of allenylphosphonates, phenylallenes, and allenyl esters: remarkable salt effect and routes to novel benzofurans and isocoumarins. |
| PubMed:Regiocontrolled intramolecular cyclizations of carboxylic acids to carbon-carbon triple bonds promoted by acid or base catalyst. |
| PubMed:Sg17-1-4, a novel isocoumarin from a marine fungus Alternaria tenuis Sg17-1. |
| PubMed:Total synthesis of (+/-)-mitorubrinic acid. |
| PubMed:Synthesis of 6-O-methyl ether of Scorzocreticin and Scorzocreticoside I, metabolites from Sorzonera cretica. |
| PubMed:Phytochemical studies and antibacterial activity of Centaurium pulchellum Druce. |
| PubMed:Investigation of a convergent route to purpuromycin: benzofuran formation vs spiroketalization. |
| PubMed:A novel isocoumarin derivative induces mitotic phase arrest and apoptosis of human multiple myeloma cells. |
| PubMed:Sensitive and selective PET-based diimidazole luminophore for Zn(II) ions: a structure-activity correlation. |
| PubMed:Tithoniamarin and tithoniamide: a structurally unique isocoumarin dimer and a new ceramide from Tithonia diversifolia. |
| PubMed:2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice. |
| PubMed:Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator. |
| PubMed:Cytotoxic flavonoids and new chromenes from Ficus formosana f. formosana. |
| PubMed:[Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi]. |
| PubMed:Mutagenic and cytotoxic effect of planifolin: a naphthopyranone dimer isolated from Paepalanthus planifolius. |
| PubMed:Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites. |
| PubMed:Structure determination of salvadorin, a novel dimeric dihydroisocoumarin from Salvadora oleoides, by NMR spectroscopy. |
| PubMed:JLK inhibitors: isocoumarin compounds as putative probes to selectively target the gamma-secretase pathway. |
| PubMed:The angiogenesis inhibitor NM-3 is active against human NSCLC xenografts alone and in combination with docetaxel. |
| PubMed:A photochemical entry to depsides: synthesis of gustastatin. |
| PubMed:Coumarin and isocoumarin as serine protease inhibitors. |
| PubMed:2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid, a small molecule isocoumarin, potentiates dexamethasone-induced apoptosis of human multiple myeloma cells. |
| PubMed:Three isocoumarins and a benzofuran from the cultured lichen mycobionts of Pyrenula sp. |
| PubMed:An isocoumarin with hepatoprotective activity in Hep G2 and primary hepatocytes from Agrimonia pilosa. |
| PubMed:A short route to enantiomerically pure benzophenanthridinone skeleton: synthesis of lactone analogues of narciclasine and lycoricidine. |
| PubMed:Legioliulin, a new isocoumarin compound responsible for blue-white autofluorescence in Legionella (Fluoribacter) dumoffii under long-wavelength UV light. |
| PubMed:Constituents from the bark of Tabebuia impetiginosa. |
| PubMed:Alkylated isocoumarins from Pituranthos scoparius. |
| PubMed:Quantitative studies and sensory analyses on the influence of cultivar, spatial tissue distribution, and industrial processing on the bitter off-taste of carrots (Daucus carota l.) and carrot products. |
| PubMed:Intestinal anti-inflammatory activity of paepalantine, an isocoumarin isolated from the capitula of Paepalanthus bromelioides, in the trinitrobenzenesulphonic acid model of rat colitis. |
| PubMed:Determination of three compounds in Aloe vera by capillary electrophoresis. |
| PubMed:Mutagenicity of paepalantine dimer and glycoside derivatives from Paepalanthus bromelioides. |
| PubMed:JLK isocoumarin inhibitors: selective gamma-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo. |
| PubMed:A new isocoumarin from bark of Pellodendron chinense. |
| PubMed:Molecule action mechanisms of NM-3 on human gastric cancer SGC-7901 cells in vivo or in vitro. |
| PubMed:Isolation and structural elucidation of 5-formyl-2,3-dihydroisocoumarin from Centaurium erythraea aerial parts. |
| PubMed:Reactivity studies of 3-alkoxy-7-amino-4-chloroisocoumarins (beta-amyloid peptide inhibitors) versus different classes of amines. |
| PubMed:Formal synthesis of angiogenesis inhibitor NM-3. |
| PubMed:Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease. |
| PubMed:Effect of the isocoumarin paepalantine on the luminol and lucigenin amplified chemiluminescence of rat neutrophils. |
| PubMed:Synthesis and antimicrobial activities of some isocoumarin and dihydroisocoumarin derivatives. |
| PubMed:Two new non-steroidal constituents from Dioscorea futschauensis R. Kunth. |
| PubMed:Convenient total synthesis of NM-3, an antiangiogenesis agent, and its optical resolution. |
| PubMed:The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species. |
| PubMed:Typhaphthalide and typharin, two phenolic compounds from Typha capensis. |
| PubMed:Amicoumacin antibiotic production and genetic diversity of Bacillus subtilis strains isolated from different habitats. |
| PubMed:Suppression of type II collagen-induced arthritis by a new isocoumarin, NM-3. |
| PubMed:Risk assessment of ochratoxin: current views of the European Scientific Committee on Food, the JECFA and the Codex Committee on Food Additives and Contaminants. |
| PubMed:Metabolites from fungi 15. New isocoumarins from an endophytic fungus isolated from the Canadian thistle Cirsium arvense. |
| PubMed:Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis. |
| PubMed:Reactions of 3-(1-Hydroxyalkyl)phthalides with Acids: Synthesis of (Z)-3-Alkylidenephthalides and 3-Alkyl-8-hydroxyisocoumarins. |
| PubMed:Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways. |
| PubMed:F13459, a new derivative of mycophenolic acid. II. Physico-chemical properties and structural elucidation. |
| PubMed:Mandibular gland chemistry of four Caribbean species of Camponotus (Hymenoptera: Formicidae). |
| PubMed:Synthesis and biological evaluation of cytogenin derivatives. |
| PubMed:Synthesis and cytotoxic activity of carboxamide derivatives of benzimidazo[2,1-a]isoquinoline and pyrido[3',2':4,5]imidazo[2,1-a]isoquinoline. |
| PubMed:Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans. |
| PubMed:NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity. |
| PubMed:Evaluation of the genotoxic potential of the isocoumarin paepalantine in in vivo and in vitro mammalian systems. |
| PubMed:Determination and distribution of 6-methoxymellein in fresh and processed carrot puree by a rapid spectrophotometric assay. |
| PubMed:Chemical and sensory quality of processed carrot puree as influenced by stress-induced phenolic compounds. |
| PubMed:The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation. |
| PubMed:Heterologous expression and product identification of Colletotrichum lagenarium polyketide synthase encoded by the PKS1 gene involved in melanin biosynthesis. |
| PubMed:Dichlorodiaportin, diaportinol, and diaportinic acid: three novel isocoumarins from penicillium nalgiovense |
| PubMed:Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells. |
| PubMed:Ochratoxin binding to phenylalanyl-tRNA synthetase: computational approach to the mechanism of ochratoxicosis and its antagonism. |
| PubMed:Differences in neurotoxic effects of ochratoxin A, ochracin and ochratoxin-alpha in vitro. |
| PubMed:Inhibition of angiogenesis by a new isocoumarin, NM-3. |
| PubMed:Regional selectivity to ochratoxin A, distribution and cytotoxicity in rat brain. |
| PubMed:Structure of 3,4-dichloroisocoumarin-inhibited factor D. |
| PubMed:Mechanism of gammadelta T cell-induced human oligodendrocyte cytotoxicity: relevance to multiple sclerosis. |
| PubMed:A serine proteinase inactivator inhibits chondrocyte-mediated cartilage proteoglycan breakdown occurring in response to proinflammatory cytokines. |
| PubMed:Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats. |
| PubMed:Functional expression of a tobacco gene related to the serine hydrolase family -- esterase activity towards short-chain dinitrophenyl acylesters. |
| PubMed:Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. |
| PubMed:Fluorometric assessments of acrosomal integrity and viability in cryopreserved bovine spermatozoa. |
| PubMed:Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones. |
| PubMed:PM-94128, a new isocoumarin antitumor agent produced by a marine bacterium. |
| PubMed:Mutagenic and cytotoxic activity of an isocoumarin (Paepalantine) isolated from Paepalanthus vellozioides. |
| PubMed:Determination of activable proacrosin/acrosin in bovine sperm using an irreversible isocoumarin serine protease inhibitor. |
| PubMed:Cercophorins A-C: novel antifungal and cytotoxic metabolites from the coprophilous fungus Cercophora areolata. |
| PubMed:Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes). |
| PubMed:Toxicity of ochratoxin A, its opened lactone form and several of its analogs: structure-activity relationships. |
| PubMed:Production of(14)C-ochratoxin A byPenicillium verrucosum sp. 1761 in liquid culture. |
| PubMed:4-Chloro-7-(iodoacetyl)amino-3-methoxy-isocoumarin. |
| PubMed:New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. IV. Structural elucidation of novel isocoumarin derivatives. |
| PubMed:Metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. III. Production of novel isocoumarin derivatives, isolation, and biological activities. |
| PubMed:Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. |
| PubMed:Mammalian tissue trypsin-like enzymes: substrate specificity and inhibitory potency of substituted isocoumarin mechanism-based inhibitors, benzamidine derivatives, and arginine fluoroalkyl ketone transition-state inhibitors. |
| PubMed:Chemical reactivity of the toxin oosponol from Gloeophyllum abietinum with nucleophilic agents. |
| PubMed:Mechanism-based isocoumarin inhibitors for blood coagulation serine proteases. Effect of the 7-substituent in 7-amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on inhibitory and anticoagulant potency. |
| PubMed:Biosynthesis of antitumor antibiotic, cytogenin. |
| PubMed:Increased gelatinolytic and caseinolytic activity in the thermally injured, nutritionally compromised rat cornea: detection of a 27-kDa lymphoreticular cell-associated caseinase. |
| PubMed:Isocoumarin inhibitors of serine peptidases. |
| PubMed:Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases. |
| PubMed:Isocladosporin, a biologically active isomer of cladosporin from Cladosporium cladosporioides. |
| PubMed:Stimulation of calcium influx and calcium cascade by cyclic AMP in cultured carrot cells. |
| PubMed:Inhibition of porcine pancreatic elastase by 7-substituted 4-chloro-3-ethoxyisocoumarins: structural characteristics of modeled noncovalent complexes relate to the measured inhibition kinetics. |
| PubMed:The receptor-destroying enzyme of influenza C virus is required for entry into target cells. |
| PubMed:Research on isoquinoline derivatives. V--Synthesis and pharmacological evaluation of a series of amidic derivatives of isoquinolin and isocoumarin carboxylic acids. |
| PubMed:Proteases--structures, mechanism and inhibitors. |
| PubMed:A new isocoumarin antibiotic, Y-05460M-A. |
| PubMed:A review of recent advances in understanding ochratoxicosis. |
| PubMed:A 3,4-dichloroisocoumarin-resistant component of the multicatalytic proteinase complex. |
| PubMed:Substituted isocoumarins as inhibitors of complement serine proteases. |
| PubMed:Sulfonyl fluoride serine protease inhibitors inactivate RNK-16 lymphocyte granule proteases and reduce lysis by granule extracts and perforin. |
| PubMed:Effect of the 7-amino substituent on the inhibitory potency of mechanism-based isocoumarin inhibitors for porcine pancreatic and human neutrophil elastases: a 1.85-A X-ray structure of the complex between porcine pancreatic elastase and 7-[(N-tosylphenylalanyl)amino]-4-chloro-3- methoxyisocoumarin. |
| PubMed:Substrate and inhibitor studies on proteinase 3. |
| PubMed:[Study on the development of biological-active compounds after the model of natural products]. |
| PubMed:The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors. |
| PubMed:Biologically active metabolites from Xenorhabdus spp., Part 2. Benzopyran-1-one derivatives with gastroprotective activity. |
| PubMed:Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex. |
| PubMed:Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins. |
| PubMed:Pharmacokinetics of ochratoxin A in animals. |
| PubMed:Thioester chromogenic substrates for human factor VIIa: substituted isocoumarins are inhibitors of factor VIIa and in vitro anticoagulants. |
| PubMed:In vivo determination of the anticoagulant effect of a substituted isocoumarin (ACITIC). |
| PubMed:Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin. |
| PubMed:Thermodynamic cycle-perturbation study of the binding of trifluoroacetyl dipeptide anilide inhibitors with porcine pancreatic elastase. |
| PubMed:Ethylene-like activity of isocyanides. |
| PubMed:Lung lymph capillary injury-related protease. |
| PubMed:Selective isocoumarin serine protease inhibitors block RNK-16 lymphocyte granule-mediated cytolysis. |
| PubMed:3-(2-Methoxyphenyl)-1H-2-benzopyran-1-one. |
| PubMed:Influenza C virus esterase: analysis of catalytic site, inhibition, and possible function. |
| PubMed:Substrate specificity and inhibitors of a capillary injury-related protease from sheep lung lymph. |
| PubMed:Structure-activity relationships among mycotoxins. |
| PubMed:Mechanism-based isocoumarin inhibitors for serine proteases: use of active site structure and substrate specificity in inhibitor design. |
| PubMed:[Studies on the structure of a new isocoumarin glucoside of the root sprouts of Agrimonia pilosa Ledeb]. |
| PubMed:Localization, implications for function, and gene expression of chymotrypsin-like proteinases of cytotoxic RNK-16 lymphocytes. |
| PubMed:Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants. |
| PubMed:Lymphocyte granule-mediated cytolysis requires serine protease activity. |
| PubMed:Reaction of serine proteases with substituted 3-alkoxy-4-chloroisocoumarins and 3-alkoxy-7-amino-4-chloroisocoumarins: new reactive mechanism-based inhibitors. |
| PubMed:Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor. |
| PubMed:1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
| PubMed:Comparative study of the effect of ochratoxin A analogues on yeast aminoacyl-tRNA synthetases and on the growth and protein synthesis of hepatoma cells. |
| PubMed:1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammoniohexanoate. |
| PubMed:Postnatal behavioral effects of ochratoxin A in offspring of treated mice. |
| PubMed:Synthesis and biological activity of spiro[isocoumarin-piperidines] and related compounds. I. |
| PubMed:Metabolic products of microorganisms. 184. On the mode of action of cladosporin. |
| PubMed:Inhibition of compound 48/80-mediated histamine release from isolated rat mast cells by oosponol-related compounds (4-acyl-isocoumarins). |
| PubMed:[Effect of a synthetic isocoumarin (F 1375) with respect to compound 48-80 (author's transl)]. |
| PubMed:Chemical structure and sweet taste of isocoumarin and related compounds. IX. |
| PubMed:Chemical structure and sweet taste of isocoumarin and related compounds. VIII. |
| PubMed:Chemical structure and sweet taste of isocoumarin and related compounds. VII. |
| PubMed:A spectrophotometric procedure, using carboxypeptidase A, for the quantitative measurement of ochratoxin A. |
| PubMed:Chemical structure and sweet taste of isocoumarin and related compounds. VI. |
| PubMed:[Experimental research on the hyperprothrombinemic activity of an isocoumarin derivative: antagonism against anticoagulant dicoumarol (Warfarin)]. |
| PubMed:Studies on the biosynthesis of isocoumarins in carrot root tissues : induction by substances other than ethylene and effects of metabolic inhibitors. |
| PubMed:Metabolism of glutamic acid in Aspergillus ochraceus during the biosynthesis of ochratoxin A. |
| PubMed:[On the antagonistic effect of an isocoumarin derivative (allyl amide of 4-phenyl-3-isocoumarinic acid) on the anticoagulant activity of 3(alpha-acetonyl-benzyl)-4-hydroxyoumarin]. |
| PubMed:[Presence of erythrocentaurine (6-formyl-dihydro-isocoumarin) in Gentiana pneumonanthe L]. |
| PubMed:[Synthesis and pharmacological activity of alkylamido-derivatives of 4-phenyl-3-isocoumarin acid]. |
| PubMed:Mellein and 4-hydroxymellein production by Aspergillus ochraceus Wilhelm. |
| PubMed:The toxicity of 5-chloro-8-hydroxy-3, 4-dihydro-3-methyl-isocoumarin-7-carboxylic acid, a hydrolyzate of ochratoxin A. |
| PubMed:[Syntheses of flavone-2-carbonic acids and chromono-(2',3'-3,4)-isocoumarin derivatives]. |
| PubMed:Biosynthesis of ochratoxin A. |
| PubMed:Ethylene-induced Isocoumarin Formation in Carrot Root Tissue. |
| PubMed:[On some conversions of 3-substituted isocoumarin derivatives]. |
| PubMed:5-oxo-5H-benzo[e]indole, a new type of highly sarcomagenic lactone. |
| PubMed:[Reaction of 4-acylhomophthalic acid anhydrides to isocoumarin-4-carboxylic acid derivatives. 6. On acyl derivatives of methylene active dicarbonyl compounds]. |
| PubMed:Reticulol, a new metabolic isocoumarin. |
| PubMed:Isocoumarin. |
3D/inchi