| PubMed:Identification of weak and gender specific effects in a short 3 weeks intervention study using barley and oat mixed linkage β-glucan dietary supplements: a human fecal metabolome study by GC-MS. |
| PubMed:Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets. |
| PubMed:Short communication: The mammalian lignan enterolactone is absorbed by newborn dairy calves fed enterolactone-enriched milk. |
| PubMed:Genistein and enterolactone in relation to Ki-67 expression and HER2 status in postmenopausal breast cancer patients. |
| PubMed:Incomplete metabolism of phytoestrogens by gut microbiota from children under the age of three. |
| PubMed:Linoleic acid, α-linolenic acid and enterolactone affect lipid oxidation and expression of lipid metabolism and antioxidant-related genes in hepatic tissue of dairy cows. |
| PubMed:Multiclass analytical method for the determination of natural/synthetic steroid hormones, phytoestrogens, and mycoestrogens in milk and yogurt. |
| PubMed:Association of Polyphenol Biomarkers with Cardiovascular Disease and Mortality Risk: A Systematic Review and Meta-Analysis of Observational Studies. |
| PubMed:Association between Dietary Share of Ultra-Processed Foods and Urinary Concentrations of Phytoestrogens in the US. |
| PubMed:Phyto-oestrogens and colorectal cancer risk: a systematic review and dose-response meta-analysis of observational studies. |
| PubMed:The treatment effects of flaxseed-derived secoisolariciresinol diglycoside and its metabolite enterolactone on benign prostatic hyperplasia involve the G protein-coupled estrogen receptor 1. |
| PubMed:Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones. |
| PubMed:Validated LC-MS/MS Method for the Quantification of Free and Bound Lignans in Cereal-Based Diets and Feces. |
| PubMed:Phytoestrogens and risk of prostate cancer: an updated meta-analysis of epidemiologic studies. |
| PubMed:Use of antibiotics is associated with lower enterolactone plasma concentration. |
| PubMed:Detection of novel metabolites of flaxseed lignans in vitro and in vivo. |
| PubMed:Whole Rye Consumption Improves Blood and Liver n-3 Fatty Acid Profile and Gut Microbiota Composition in Rats. |
| PubMed:Binding of enterolactone and enterodiol to human serum albumin: increase of cysteine-34 thiol group reactivity. |
| PubMed:Effect of bovine ABCG2 polymorphism Y581S SNP on secretion into milk of enterolactone, riboflavin and uric acid. |
| PubMed:Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer. |
| PubMed:Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice. |
| PubMed:Serum levels of phytoestrogens as biomarkers of intake in Mexican women. |
| PubMed:Targeted LC-MS/MS Method for the Quantitation of Plant Lignans and Enterolignans in Biofluids from Humans and Pigs. |
| PubMed:Gut metabolites and bacterial community networks during a pilot intervention study with flaxseeds in healthy adult men. |
| PubMed:Bioactivation of Phytoestrogens: Intestinal Bacteria and Health. |
| PubMed:Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats. |
| PubMed:Enterolignan-producing phenotypes are associated with increased gut microbial diversity and altered composition in premenopausal women in the United States. |
| PubMed:Interactions of corn meal or molasses with a soybean-sunflower meal mix or flaxseed meal on production, milk fatty acid composition, and nutrient utilization in dairy cows fed grass hay-based diets. |
| PubMed:The anti-proliferative effects of enterolactone in prostate cancer cells: evidence for the role of DNA licencing genes, mi-R106b cluster expression, and PTEN dosage. |
| PubMed:Effects of different n-6:n-3 fatty acid ratios and of enterolactone on gene expression and PG secretion in bovine endometrial cells. |
| PubMed:Gastrointestinal metabolism of phytoestrogens in lactating dairy cows fed silages with different botanical composition. |
| PubMed:Gene expression profiling of sesaminol triglucoside and its tetrahydrofuranoid metabolites in primary rat hepatocytes. |
| PubMed:Ruminal Prevotella spp. may play an important role in the conversion of plant lignans into human health beneficial antioxidants. |
| PubMed:Role of ABCG2 in transport of the mammalian lignan enterolactone and its secretion into milk in Abcg2 knockout mice. |
| PubMed:Oilseeds ameliorate metabolic parameters in male mice, while contained lignans inhibit 3T3-L1 adipocyte differentiation in vitro. |
| PubMed:Preventive effects of lignan extract from flax hulls on experimentally induced benign prostate hyperplasia. |
| PubMed:Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans. |
| PubMed:Bioaccessibility of lignans from flaxseed (Linum usitatissimum L.) determined by single-batch in vitro simulation of the digestive process. |
| PubMed:Phenols, lignans and antioxidant properties of legume and sweet chestnut flours. |
| PubMed:Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. |
| PubMed:UPLC-QTOF/MS metabolic profiling unveils urinary changes in humans after a whole grain rye versus refined wheat bread intervention. |
| PubMed:Supported liquid extraction in the quantitation of plasma enterolignans using isotope dilution GC/MS with application to flaxseed consumption in healthy adults. |
| PubMed:Global metabolomics reveals urinary biomarkers of breast cancer in a mcf-7 xenograft mouse model. |
| PubMed:Anti-proliferative effects of physiological concentrations of enterolactone in models of prostate tumourigenesis. |
| PubMed:Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort. |
| PubMed:Validation of FFQ-based assessment of dietary lignans compared with serum enterolactone in Swedish women. |
| PubMed:Tissue distribution and cytochrome P450 inhibition of sesaminol and its tetrahydrofuranoid metabolites. |
| PubMed:Effects of abomasal infusion of flaxseed (Linum usitatissimum) oil on microbial β-glucuronidase activity and concentration of the mammalian lignan enterolactone in ruminal fluid, plasma, urine and milk of dairy cows. |
| PubMed:Identification of enterodiol as a masker for caffeine bitterness by using a pharmacophore model based on structural analogues of homoeriodictyol. |
| PubMed:Correlations of urinary phytoestrogen excretion with lifestyle factors and dietary intakes among middle-aged and elderly Chinese women. |
| PubMed:Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads. |
| PubMed:Mammary gene expression and activity of antioxidant enzymes and concentration of the mammalian lignan enterolactone in milk and plasma of dairy cows fed flax lignans and infused with flax oil in the abomasum. |
| PubMed:(-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice. |
| PubMed:Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer. |
| PubMed:Association between dietary phyto-oestrogens and bone density in men and postmenopausal women. |
| PubMed:Effects of a safflower tea supplement on antioxidative status and bone markers in postmenopausal women. |
| PubMed:Intestinal distribution and excretion of sesaminol and its tetrahydrofuranoid metabolites in rats. |
| PubMed:Effect of flaxseed lignans added to milk or fed to cows on oxidative degradation of dairy beverages enriched with polyunsaturated fatty acids. |
| PubMed:Estrogenic activities of sesame lignans and their metabolites on human breast cancer cells. |
| PubMed:Effect of dietary intervention on serum lignan levels in pregnant women - a controlled trial. |
| PubMed:Whole and fractionated yellow pea flours reduce fasting insulin and insulin resistance in hypercholesterolaemic and overweight human subjects. |
| PubMed:Profiles of phytoestrogens in human urine from several Asian countries. |
| PubMed:Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling. |
| PubMed:Assessment of information to substantiate a health claim on the prevention of prostate cancer by lignans. |
| PubMed:Influence of lignans depletion on murine mammary gland morphology. |
| PubMed:Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database. |
| PubMed:Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents. |
| PubMed:The interaction of monensin and flaxseed hulls on ruminal and milk concentration of the mammalian lignan enterolactone in late-lactating dairy cows. |
| PubMed:Concentration of the mammalian lignans enterolactone and enterodiol in milk of cows fed diets containing different concentrations of whole flaxseed. |
| PubMed:Gastrointestinal microflora, food components and colon cancer prevention. |
| PubMed:Weekly excretion of the mammalian lignan enterolactone in milk of dairy cows fed flaxseed meal. |
| PubMed:Further studies on a human intestinal bacterium Ruminococcus sp. END-1 for transformation of plant lignans to mammalian lignans. |
| PubMed:Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice. |
| PubMed:Impact of a lignan-rich diet on adiposity and insulin sensitivity in post-menopausal women. |
| PubMed:Biotransformation of sesaminol triglucoside to mammalian lignans by intestinal microbiota. |
| PubMed:Tissue distribution and elimination of sesaminol triglucoside and its metabolites in rat. |
| PubMed:Milk concentration of the mammalian lignan enterolactone, milk production, milk fatty acid profile, and digestibility in dairy cows fed diets containing whole flaxseed or flaxseed meal. |
| PubMed:Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens. |
| PubMed:In vitro metabolism of flax lignans by ruminal and faecal microbiota of dairy cows. |
| PubMed:Isolation and bioactivities of furfuran type lignan compounds from edible plants. |
| PubMed:Phytoestrogens and phytoestrogen metabolites differentially modulate immune parameters in human leukocytes. |
| PubMed:Phytoestrogen content of foods of animal origin: dairy products, eggs, meat, fish, and seafood. |
| PubMed:Fecal and urinary lignans, intrafollicular estradiol, and endometrial receptors in lactating dairy cows fed diets supplemented with hydrogenated animal fat, flaxseed or sunflower seed. |
| PubMed:Effects of clover-grass silages and concentrate supplementation on the content of phytoestrogens in dairy cow milk. |
| PubMed:Metabolism of the lignan macromolecule into enterolignans in the gastrointestinal lumen as determined in the simulator of the human intestinal microbial ecosystem. |
| PubMed:Environmental exposures and puberty in inner-city girls. |
| PubMed:Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERalpha transcriptional activation in human breast cancer cells. |
| PubMed:Effect of the form of the sesame-based diet on the absorption of lignans. |
| PubMed:Enterolactone restricts the proliferation of the LNCaP human prostate cancer cell line in vitro. |
| PubMed:Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia. |
| PubMed:Lignan content of selected foods from Japan. |
| PubMed:Lignans and human health. |
| PubMed:The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis. |
| PubMed:Dietary fiber intake and endogenous serum hormone levels in naturally postmenopausal Mexican American women: the Multiethnic Cohort Study. |
| PubMed:Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro. |
| PubMed:Can the combination of flaxseed and its lignans with soy and its isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast cancer? |
| PubMed:Role of dietary lignans in the reduction of breast cancer risk. |
| PubMed:Tissue distribution of lignans in rats in response to diet, dose-response, and competition with isoflavones. |
| PubMed:Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake. |
| PubMed:Validation of a phytoestrogen food frequency questionnaire with urinary concentrations of isoflavones and lignan metabolites in premenopausal women. |
| PubMed:Intake of dietary phytoestrogen and indices of antioxidant and bone metabolism of pre- and post-menopausal Korean women. |
| PubMed:Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk. |
| PubMed:Assessing exposure to lignans and their metabolites in humans. |
| PubMed:Flax lignans--analytical methods and how they influence our lunderstanding of biological activity. |
| PubMed:Urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. |
| PubMed:Phyto-oestrogen intake and plasma concentrations in South Asian and native British women resident in England. |
| PubMed:Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities. |
| PubMed:Analysis of enterolignan glucuronides in serum and urine by HPLC-ESI-MS. |
| PubMed:Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden). |
| PubMed:A lignan complex isolated from flaxseed does not affect plasma lipid concentrations or antioxidant capacity in healthy postmenopausal women. |
| PubMed:The relative bioavailability of enterolignans in humans is enhanced by milling and crushing of flaxseed. |
| PubMed:Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men. |
| PubMed:Whole sesame seed is as rich a source of mammalian lignan precursors as whole flaxseed. |
| PubMed:Dietary phytoestrogens and lung cancer risk. |
| PubMed:A validated method for the quantification of enterodiol and enterolactone in plasma using isotope dilution liquid chromatography with tandem mass spectrometry. |
| PubMed:Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. |
| PubMed:Intake of the plant lignans secoisolariciresinol, matairesinol, lariciresinol, and pinoresinol in Dutch men and women. |
| PubMed:Dietary sesamin is converted to enterolactone in humans. |
| PubMed:Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside. |
| PubMed:Uptake and metabolism of enterolactone and enterodiol by human colon epithelial cells. |
| PubMed:A thirteen week dietary toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats. |
| PubMed:A semiquantitative food frequency questionnaire is a valid indicator of the usual intake of phytoestrogens by south Asian women in the UK relative to multiple 24-h dietary recalls and multiple plasma samples. |
| PubMed:Intake of whole grains and vegetables determines the plasma enterolactone concentration of Danish women. |
| PubMed:Prenatal developmental toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats. |
| PubMed:Dietary lignan intakes and risk of pre- and postmenopausal breast cancer. |
| PubMed:A single measurement is inadequate to estimate enterolactone levels in danish postmenopausal women due to large intraindividual variation. |
| PubMed:Chemopreventive effects of hydroxymatairesinol on uterine carcinogenesis in Donryu rats. |
| PubMed:Studies on the metabolism of the plant lignans secoisolariciresinol and matairesinol. |
| PubMed:Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry. |
| PubMed:Rye, lignans and human health. |
| PubMed:Bioavailability of phyto-oestrogens. |
| PubMed:Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry. |
| PubMed:Whole-grain rye and wheat foods and markers of bowel health in overweight middle-aged men. |
| PubMed:Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats. |
| PubMed:Phytoestrogens and breast cancer. |
| PubMed:Isoflavonoid and lignan phytoestrogens as dietary biomarkers. |
| PubMed:Phloem fortification in rye bread elevates serum enterolactone level. |
| PubMed:The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women. |
| PubMed:Mammalian lignan formation in rats fed a wheat bran diet. |
| PubMed:Oxidative metabolites and genotoxic potential of mammalian and plant lignans in vitro. |
| PubMed:Whole grain food intake elevates serum enterolactone. |
| PubMed:The effect of flaxseed supplementation in processed foods on serum fatty acids and enterolactone. |
| PubMed:Dietary determinants of plasma enterolactone. |
| PubMed:In vitro metabolism of plant lignans: new precursors of mammalian lignans enterolactone and enterodiol. |
| PubMed:Determinants of serum enterolactone concentration. |
| PubMed:Serum enterolactone and risk of breast cancer: a case-control study in eastern Finland. |
| PubMed:[Selected phytoestrogens with potential beneficial effects on risk of certain environmental diseases]. |
| PubMed:Consumption of wholemeal rye bread increases serum concentrations and urinary excretion of enterolactone compared with consumption of white wheat bread in healthy Finnish men and women. |
| PubMed:Antioxidants in vegan diet and rheumatic disorders. |
| PubMed:Extraction and quantification of lignan phytoestrogens in food and human samples. |
| PubMed:Flaxseed influences urinary lignan excretion in a dose-dependent manner in postmenopausal women. |
| PubMed:Oxidative metabolites of the mammalian lignans enterodiol and enterolactone in rat bile and urine. |
| PubMed:Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora. |
| PubMed:Urinary isoflavonoid and lignan excretion on a Western diet: relation to soy, vegetable, and fruit intake. |
| PubMed:Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. |
| PubMed:Risk of acute coronary events according to serum concentrations of enterolactone: a prospective population-based case-control study. |
| PubMed:Oxidative metabolism of the mammalian lignans enterolactone and enterodiol by rat, pig, and human liver microsomes. |
| PubMed:Novel metabolites of the mammalian lignans enterolactone and enterodiol in human urine. |
| PubMed:Analysis of phyto-oestrogens by gas chromatography-mass spectrometry. |
| PubMed:Phytoestrogens. State of the art. |
| PubMed:Time-resolved fluoroimmunoassay for plasma enterolactone. |
| PubMed:Method for measurement of dietary secoisolariciresinol using HPLC with multichannel electrochemical detection. |
| PubMed:Immunoassay of phytoestrogens in human plasma. |
| PubMed:Phyto-oestrogen excretion and rate of bone loss in postmenopausal women. |
| PubMed:Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors. |
| PubMed:Studies on the genotoxicity of the mammalian lignans enterolactone and enterodiol and their metabolic precursors at various endpoints in vitro. |
| PubMed:Analysis of phytoestrogens and polyphenols in plasma, tissue, and urine using HPLC with coulometric array detection. |
| PubMed:Urinary isoflavonoid excretion in humans is dose dependent at low to moderate levels of soy-protein consumption. |
| PubMed:Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. |
| PubMed:Fecal lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. |
| PubMed:Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products. |
| PubMed:Effect of diet on lignans and isoflavonoid phytoestrogens in chimpanzees. |
| PubMed:Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets. |
| PubMed:Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes. |
| PubMed:Determination of lignans and isoflavonoids in human female plasma following dietary supplementation. |
| PubMed:Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. |
| PubMed:Effect of flax seed ingestion on the menstrual cycle. |
| PubMed:Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens. |
| PubMed:Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. |
| PubMed:Mammalian lignan production from various foods. |
| PubMed:Endogenous digoxin-like activity of mammalian-lignans and their derivatives. |
| PubMed:Detection and identification of the plant lignans lariciresinol, isolariciresinol and secoisolariciresinol in human urine. |
| PubMed:Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. |
3D/inchi