EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ginkgolide B
(1beta)-1-hydroxyginkgolide A

Supplier Sponsors

CAS Number: 15291-77-7Picture of molecule3D/inchi
FDA UNII: DF149B9460
MDL:MFCD05662347
XlogP3-AA:-0.40 (est)
Molecular Weight:424.40328000
Formula:C20 H24 O10
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 762.00 to 763.00 °C. @ 760.00 mm Hg (est)
Flash Point: 526.00 °F. TCC ( 274.30 °C. ) (est)
logP (o/w): 2.070 (est)
Soluble in:
 water, 1.838e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ginkgolide B 98%
BOC Sciences
For experimental / research use only.
Ginkgolide B >98%
Odor: characteristic
Use: Ginkgolide B is a PAFR antagonist with IC50 of 3.6 nM.
ExtraSynthese
For experimental / research use only.
Ginkgolide B (HPLC) ≥98%
Nacalai USA
For experimental / research use only.
Ginkgolide B
Santa Cruz Biotechnology
For experimental / research use only.
Ginkgolide B ≥90%
Sigma-Aldrich: Sigma
For experimental / research use only.
Ginkgolide B from Ginkgo biloba leaves ≥90% (HPLC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ginkgolide B usage levels up to:
 not for fragrance use.
 
Recommendation for ginkgolide B flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :65243
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0015291777
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):65243
Pubchem (sid):135022899
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):C07602
HMDB (The Human Metabolome Database):HMDB36861
FooDB:FDB015815
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ginkgo biloba
Search Trop Picture
 
Synonyms:
11-tert-butyl-1,4b,8-trihydroxy-5-methyltetrahydro-4bh,9h-9,4a-(epoxymethano)cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1h,5h)-trione
8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
 ginkolide B
(1beta)-1-hydroxyginkgolide A
 

Articles:

PubMed:A novel oil-body nanoemulsion formulation of ginkgolide B: pharmacokinetics study and in vivo pharmacodynamics evaluations.
PubMed:Ginkgolide B prevents cathepsin-mediated cell death following cerebral ischemia/reperfusion injury.
PubMed:Two new nonacosanetriols from Ginkgo biloba sarcotesta.
PubMed:Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
PubMed:Column liquid chromatography/electrospray ionization-time of flight-mass spectrometry and ultraperformance column liquid chromatography/mass spectrometry methods for the determination of ginkgolides and bilobalide in the leaves of Ginkgo biloba and dietary supplements.
PubMed:In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
PubMed:A method for extraction and quantification of Ginkgo terpene trilactones.
PubMed:Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations.
PubMed:Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice.
PubMed:Selective responses of three Ginkgo biloba leaf-derived constituents on human intestinal bacteria.
PubMed:Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts.
PubMed:[Pharmacokinetic properties of Bilobalide and Ginkgolides A and B in healthy subjects after intravenous and oral administration of Ginkgo biloba extract (EGb 761)].
PubMed:Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics.
 
Notes:
a paf-receptor antagonist; isolated from ginkgo biloba tree; the most active ginkgolide at antagonizing paf receptors. Isol. from Ginkgo biloba (ginkgo)
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