lutein, 127-40-2

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CODE137310 CODE137310
Product(s):
LP10PB LUTEIN MC 10% Plus 1% ZEAXANTHIN

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CODE137310 CODE137310
Product(s):
127-40-2 Xanthophyll 0.95
Xanthophyll is a widespread carotenoid alcohols and could be obtained from some natural plants. anti-tumor; anti-cancer; antimutagenic; antibacterial; antimicrobial;

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CODE137310 CODE137310
Product(s):
GK2391 Xanthophyll

CAS Number:	127-40-2	3D/inchi
ECHA EINECS - REACH Pre-Reg:	204-840-0
FDA UNII:	X72A60C9MT
Beilstein Number:	2068547
MDL:	MFCD08435941
XlogP3-AA:	11.00 (est)
Molecular Weight:	568.88472000
Formula:	C40 H56 O2
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:color agents, nutrient supplements

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
	FDA/DG SANTE Petitions, Reviews, Notices:
GRN 390	Suspended lutein View - notice PDF
GRN 385	Lutein View - notice PDF
GRN 291	Crystalline lutein View - notice PDF
GRN 140	Crystalline lutein View - notice PDF
GRN 221	Suspended lutein View - notice PDF
EU SANCO	Lutein View - review
GRN 542	Lutein View - notice PDF
JECFA Food Additive:	Lutein from Tagetes erecta Mixed Carotenoids
GSFA Codex:	Lutein from Tagetes erecta (161b(i))
DG SANTE Food Additives:	lutein
FDA Mainterm (SATF):	127-40-2 ; XANTHOPHYLL
FDA Regulation:
FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.275 Dried algae meal. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.295 Tagetes (Aztec marigold) meal and extract. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.315 Corn endosperm oil.

Physical Properties:

Appearance:	orange red powder (est)
Assay:	80.00 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	196.00 °C. @ 760.00 mm Hg
Boiling Point:	702.27 °C. @ 760.00 mm Hg (est)
Flash Point:	516.00 °F. TCC ( 269.10 °C. ) (est)
logP (o/w):	11.524 (est)
Soluble in:
	hexane
	water, 5.631e-011 mg/L @ 25 °C (est)
Insoluble in:
	water

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	skin conditioning

Suppliers:

AIDP

Lutein 5% Beadlets 5%

Alfa Biotechnology

For experimental / research use only.

Lutein 98%

Allied Biotech

Lutene 10% TG

Flavor: characteristic

is a Tablet Grade version of lutein being used in multivitamins and other dietary supplements.

Allied Biotech

Lutene 10% WSC

Flavor: characteristic

is a powder formulation of lutein developed for water based applications to impart a yellow color.

Allied Biotech

Lutene 15% EM

Flavor: characteristic

is an oil in water emulsion system which will provide a yellow shade for water based applications.

American International Chemical, LLC.

LUTEIN MC 10% Plus 1% ZEAXANTHIN

For experimental / research use only.

Xanthophyll 0.95

Odor: characteristic

Use: Xanthophyll is a widespread carotenoid alcohols and could be obtained from some natural plants. anti-tumor; anti-cancer; antimutagenic; antibacterial; antimicrobial;

Changsha Organic Herb

Marigold Extract Lutein

Chr. Hansen A/S

Luteins

Flavor: characteristic

Lutein is obtained from marigold flowers, Tagetes erecta, found abundantly throughout Mexico. Lutein is a warm, yellow color and is used in products such as juices and cakes. The color displays good light, heat and pH stability. The pigment is also used in functional foods, being favored for its antioxidant properties.

Coompo

For experimental / research use only.

Lutein from Plants ≥96%

DSM Nutritional

FloraGLO^® Lutein

ExtraSynthese

For experimental / research use only.

Lutein UV ≥95%

Farbest-Tallman Foods

ZMC Natural Lutein 20% Oil Dispersion

Flavor: bland

This product is used in dietary supplement applications including soft gel capsules for eye health.

Farbest-Tallman Foods

ZMC Natural Lutein 5% CWS-S

Flavor: bland

It is used as a nutrient supplement for baking, beverages, confectionary and dairy products.

Farbest-Tallman Foods

ZMC Natural Lutein 5% TAB

Flavor: bland

It is used as a nutrient for tablet or hard-shell eye health capsule preparations.

Glentham Life Sciences

Xanthophyll

Indis NV

For experimental / research use only.

Lutein (Marigold extract)

Qingdao Dacon Trading

Lutein

Rung International

Lutein

Odor: characteristic

Use: A type of carotenoid found in most green vegetables which positively contributes to maintenance of eye vision. Its major source is the marigold. It is classified as xanthophyll.

Sigma-Aldrich: Sigma

For experimental / research use only.

Xanthophyll from marigold

sds

Sinoway Industrial

For experimental / research use only.

Lutein

Synthite Industries

Lutein 75% crystalline/ Pure Lutein

E-books and Brochures

Odor: characteristic

Use: coadjuvant in the topical treatment of cellulitis

Vevy Europe

FITOXANTINA

Odor: characteristic

Use: xantophyll-rich extract, emollient, natural dye

WILD Flavors

Lutein Ester Emulsions

Flavor: taste

Lutein is a member of the carotenoid family, a group of chemicals related to vitamin A that give color to certain fruits and vegetables. Lutein is found in nature as a fatty acid ester and is an antioxidant that is beneficial for skin and eye health.

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
color agents, nutrient supplements
Recommendation for lutein usage levels up to:
	not for fragrance use.

Recommendation for lutein flavor usage levels up to:
	not for flavor use.

Safety References:

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the re-evaluation of lutein (E 161b) as a food additive
View page or View pdf

Scientific Opinion on the re-evaluation of lutein preparations other than lutein with high concentrations of total saponified carotenoids at levels of at least 80%
View page or View pdf

Statement on the safety assessment of the exposure to lutein preparations based on new data on the use levels of lutein
View page or View pdf

Scientific Opinion on the substantiation of a health claim related to a combination of lutein and zeaxanthin and improved vision under bright light conditions pursuant to Article 13(5) of Regulation (EC) No 1924/2006
View page or View pdf

NWT-02, a fixed combination of lutein, zeaxanthin and docosahexaenoic acid in egg yolk and reduction of the loss of vision: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006
View page or View pdf

Safety and efficacy of lutein and lutein/zeaxanthin extracts from Tagetes erecta for poultry for fattening and laying (except turkeys)
View page or View pdf

EPI System: View

ClinicalTrials.gov:search

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):127-40-2

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6433159

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5

Chemidplus:0000127402

References:

	(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6433159
Pubchem (sid):	134974058

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
KEGG (GenomeNet):	C08601
HMDB (The Human Metabolome Database):	HMDB03233
FooDB:	FDB015471
YMDB (Yeast Metabolome Database):	YMDB01519
FDA Listing of Food Additive Status:	View
FDA Color Additive Status List	View
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

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Synonyms:

beta,(E)-	carotene-3,3'-diol
	fitoestesina eth-F (Vevy)
	fitoxantina (Vevy)
	lutein
floraglo	lutein
	lutein (marigold extract)
ZMC natural	lutein 20% Oil Dispersion
ZMC natural	lutein 5% CWS-S
ZMC natural	lutein 5% TAB
	lutein from Tagetes erecta
	vegetable llutein
	vegetable luteol
	xanthophyll
all-trans-(+)-	xanthophyll
	xanthophyll from marigold

Articles:

Info:Lutein and Zeaxanthin

PubMed:Oxidative stability of yogurt with added lutein dye.

PubMed:Increase in β-ionone, a carotenoid-derived volatile in zeaxanthin-biofortified sweet corn.

PubMed:UV-B radiation impacts shoot tissue pigment composition in Allium fistulosum L. cultigens.

PubMed:Identifying carotenoids and phenolic compounds in naranjilla (Solanum quitoense Lam. var. Puyo hybrid), an Andean fruit.

PubMed:Bioconversion of lutein using a microbial mixture--maximizing the production of tobacco aroma compounds by manipulation of culture medium.

PubMed:Kale carotenoids remain stable while flavor compounds respond to changes in sulfur fertility.

PubMed:Enhanced levels of the aroma and flavor compound S-linalool by metabolic engineering of the terpenoid pathway in tomato fruits.

Notes:

a carotenoid alcohol widespread in nature. it is present in egg yolk, algae, and petals of yellow flowers, among other sources. Pigment from egg yolk and leaves. Found in all higher plants. Nutriceutical with anticancer and antioxidation props. Potentially useful for the treatment of age-related macular degeneration (AMD) of the eye Lutein is a xanthophyll and one of 600 known naturally-occurring carotenoids. The principal natural stereoisomer of lutein is (3R,3?R,6?R)-beta,epsilon-carotene-3,3?-diol. (Wikipedia)

lutein all-trans-(+)-xanthophyll

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Articles:

lutein
all-trans-(+)-xanthophyll