EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

zinc gluconate (1:2)
bis(D-gluconato-O(sup 1),O(sup 2))zinc

Supplier Sponsors

CAS Number: 4468-02-4Picture of molecule3D/inchi
Other(deleted CASRN):116088-00-7
ECHA EINECS - REACH Pre-Reg:224-736-9
FDA UNII: U6WSN5SQ1Z
MDL:MFCD04037230
Molecular Weight:457.69208000
Formula:C12 H24 O14 Zn
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.8988 Zinc gluconate View - review
FDA Mainterm (SATF):4468-02-4 ; ZINC GLUCONATE
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8988 Zinc gluconate.
 
Physical Properties:
Food Chemicals Codex Listed: No
Boiling Point: 673.60 °C. @ 760.00 mm Hg (est)
Flash Point: 707.00 °F. TCC ( 375.20 °C. ) (est)
logP (o/w): -3.175 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: deodorants
skin conditioning
 
Suppliers:
American International Chemical, LLC.
ZINC GLUCONATE GRANULAR USP FCC
BASF
Affinisphere™ Marine
BOC Sciences
For experimental / research use only.
D-Gluconic acid zinc (II) salt
Carbosynth
For experimental / research use only.
Gluconic acid zinc (II) salt
Charkit Chemical
ZINC GLUCONATE
ECSA Chemicals
ZINCGLUCONATE PH.EUR.
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
EMD Millipore
For experimental / research use only.
Zinc gluconate
Glentham Life Sciences
Gluconic acid zinc(II) salt
Global Calcium
Zinc Gluconate EP
Global Calcium
Zinc Gluconate USP
Jost Chemical
Zinc Gluconate USP Granular
Jost Chemical
Zinc Gluconate USP Low HM Granular
Jost Chemical
Zinc Gluconate USP Low HM Powder
Jost Chemical
Zinc Gluconate USP Powder
Penta International
ZINC GLUCONATE FCC
Penta International
ZINC GLUCONATE DIHYDRATE USP
Prinova
Zinc Gluconate
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 1290 mg/kg
Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 24, Pg. 115, 1989.

intravenous-mouse LD50 23.70 mg/kg
Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 24, Pg. 115, 1989.

oral-man TDLo 47 mg/kg
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Toxicology, Clinical Toxicology. Vol. 36, Pg. 99, 1998.

intravenous-mouse LD50 23700 ug/kg
Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 24, Pg. 115, 1989.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nutrient supplements
Recommendation for zinc gluconate (1:2) usage levels up to:
 not for fragrance use.
 
Recommendation for zinc gluconate (1:2) flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):4468-02-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :20543
National Institute of Allergy and Infectious Diseases:Data
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid; zinc
Chemidplus:0004468024
RTECS:ZH3750000 for cas# 4468-02-4
 
References:
 (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid; zinc
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:4468-02-4
Pubchem (cid):20543
Pubchem (sid):134985871
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB32810
FooDB:FDB010784
FDA Listing of Food Additive Status:View
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•because of difficulties of preparing solid crystal product, gluconic acid of commerce is 50% aq soln... •grades: technical, 50% soln.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 deodorants
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 affinispherezinc gluconate
bis(D-gluconato-O(sup 1),O(sup 2))-zinc
bis(dextro-gluconato-O(sup 1),O(sup 2))-zinc
bis(D-gluconato-O(sup 1),O(sup 2))zinc
bis(D-gluconato-O1,O2) zinc
bis(D-gluconato-O1,O2)zinc
bis(dextro-gluconato-O1,O2)zinc
 gluconic acid zinc (II) salt
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid; zinc
 rubozine
 zicam
 zinc bis(D-gluconato-O1,O2)
 zinc bis(dextro-gluconato-O1,O2)
 zinc D-gluconate (1:2)
 zinc dextro-gluconate (1:2)
 zinc gluconate
 zinc gluconate anhydrous granular
 zinc gluconate granular USP
 zinc gluconate USP FCC granular
 zinc gluconate USP FCC powder
 zinc, bis(D-gluconato-O(sup 1),O(sup 2))- (9CI)
 zinc, bis(D-gluconato-O1,O2)-
 

Articles:

PubMed:Effect of Short Term Zinc Supplementation on Iron Status of Children with Acute Diarrhea.
PubMed:The bioavailability of different zinc compounds used as human dietary supplements in rat prostate: a comparative study.
PubMed:Drug delivery of zinc to Barrett's metaplasia by oral administration to Barrett's esophagus patients.
PubMed:Zinc mono-therapy in pre-symptomatic Chinese children with Wilson disease: a single center, retrospective study.
PubMed:[Yiqi Zhujing granule for idiopathic oligoasthenozoospermia: a clinical study].
PubMed:Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis.
PubMed:Effect of zinc supplementation on inflammatory markers and adipokines in young obese women.
PubMed:Effects of zinc supplementation on the anthropometric measurements, lipid profiles and fasting blood glucose in the healthy obese adults.
PubMed:Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.
PubMed:Injection of a chemical castration agent, zinc gluconate, into the testes of cats results in the impairment of spermatogenesis: a potentially irreversible contraceptive approach for this species?
PubMed:Necrosuppurative Orchitis and Scrotal Necrotizing Dermatitis Following Intratesticular Administration of Zinc Gluconate Neutralized With Arginine (EsterilSol) in 2 Mixed-Breed Dogs.
PubMed:Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice.
PubMed:Short-term clinical effects of photodynamic therapy with topical 5-aminolevulinic acid for facial acne conglobata: an open, prospective, parallel-arm trial.
PubMed:Different strains of Propionibacterium acnes modulate differently the cutaneous innate immunity.
PubMed:In vivo lung deposition and sub-acute inhalation toxicity studies of nano-sized alendronate sodium as an antidote for inhaled toxic substances in Sprague Dawley rats.
PubMed:Elevated urine zinc concentration reduces the detection of methamphetamine, cocaine, THC and opiates in urine by EMIT.
PubMed:Zinc for the common cold.
PubMed:Combined iron and zinc supplementation improves haematologic status of pregnant women in Upper West Region of Ghana.
PubMed:Lack of protective effects of zinc gluconate against rat colon carcinogenesis.
PubMed:Anosmia does not impair the anxiolytic-like effect of lavender essential oil inhalation in mice.
PubMed:Intratesticular injection of a zinc-based solution for contraception of domestic cats: a randomized clinical trial of efficacy and safety.
PubMed:A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
PubMed:Cubozoan venom-induced cardiovascular collapse is caused by hyperkalemia and prevented by zinc gluconate in mice.
PubMed:The efficacy of zinc supplementation in young children with acute lower respiratory infections: a randomized double-blind controlled trial.
PubMed:Selenium and zinc internalized by Lactobacillus buchneri Lb26 (DSM 16341) and Bifidobacterium lactis Bb1 (DSM 17850): improved bioavailability using a new biological approach.
PubMed:Human β-defensin-2 and psoriasin, two new innate immunity targets of zinc gluconate.
PubMed:Effect of zinc supplementation on insulin resistance and metabolic risk factors in obese Korean women.
PubMed:Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis.
PubMed:A comparison of the cellular actions of polaprezinc (zinc-L-carnosine) and ZnCl2.
PubMed:Oral administration of an anti-inflammatory does not compromise the efficacy of intra-testicular injection of zinc gluconate as a contraceptive for dogs.
PubMed:Guideline for the management of acute sore throat.
PubMed:The effect of Breezy candy on halitosis: a double-blind, controlled, and randomized study.
PubMed:Root metabolic response of rice (Oryza sativa L.) genotypes with contrasting tolerance to zinc deficiency and bicarbonate excess.
PubMed:Zinc supplements for preventing otitis media.
PubMed:Zinc gluconate is an agonist of peroxisome proliferator-activated receptor-α in the epidermis.
PubMed:Effect of dietary zinc and phytase supplementation on botulinum toxin treatments.
PubMed:Zinc for colds? Yes, but don’t swallow whole!
PubMed:Following glucose oxidase activity by chemiluminescence and chemiluminescence resonance energy transfer (CRET) processes involving enzyme-DNAzyme conjugates.
PubMed:[Study on the effect of di-(2-ethylhexyl) phthalate on pregnant rats and the protection of zinc against it in pregnancy].
PubMed:Effects of zinc gluconate and 2 other divalent cationic compounds on olfactory function in mice.
PubMed:Permanent contraception of dogs induced with intratesticular injection of a Zinc Gluconate-based solution.
PubMed:Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen.
PubMed:Antimicrobial effects of o-cymen-5-ol and zinc, alone & in combination in simple solutions and toothpaste formulations.
PubMed:Hidradenitis suppurativa: the role of deficient cutaneous innate immunity.
PubMed:Oral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levels.
PubMed:ORS containing zinc does not reduce duration or stool volume of acute diarrhea in hospitalized children.
PubMed:Inhibitory effect of zinc on the absorption of JBP485 via the gastrointestinal oligopeptide transporter (PEPT1) in rats.
PubMed:Anti-inflammatory properties of a new undecyl-rhamnoside (APRC11) against P. acnes.
PubMed:Efficacy of zinc in reducing hyperbilirubinemia among at-risk neonates: a randomized, double-blind, placebo-controlled trial.
PubMed:Effects of intratesticular zinc gluconate treatment on testicular dimensions, echodensity, histology, sperm production, and testosterone secretion in American black bears (Ursus americanus).
PubMed:Complementary and alternative medicine for prevention and treatment of the common cold.
PubMed:Novel neoadjuvant immunotherapy regimen safety and survival in head and neck squamous cell cancer.
PubMed:Supplemented zinc does not alter mood in healthy older European adults--a randomised placebo-controlled trial: the Zenith study.
PubMed:Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period.
PubMed:Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months.
PubMed:Zinc in the treatment of idiopathic sudden sensorineural hearing loss.
PubMed:Propionibacterium acnes activates the IGF-1/IGF-1R system in the epidermis and induces keratinocyte proliferation.
PubMed:Plasma zinc, copper, and serum thyroid hormones and insulin levels after zinc supplementation followed by placebo in competitive athletes.
PubMed:On the effects of a plant extract of Orthosiphon stamineus on sebum-related skin imperfections.
PubMed:The Bradford Hill criteria and zinc-induced anosmia: a causality analysis.
PubMed:Surface engineering of quantum dots for in vivo imaging.
PubMed:A phase 1 safety study of an IRX-2 regimen in patients with squamous cell carcinoma of the head and neck.
PubMed:The therapeutic effect and the changed serum zinc level after zinc supplementation in alopecia areata patients who had a low serum zinc level.
PubMed:Sorbitol production using recombinant Zymomonas mobilis strain.
PubMed:[An acrodermatitis-enteropathica-like eruption in an exclusively breast-fed premature infant].
PubMed:Zinc supplements for preventing otitis media.
PubMed:Localized scleroderma and zinc: a pilot study.
PubMed:A case of transient zinc deficiency in a breast-fed preterm infant successfully treated with oral zinc supplementation: review of zinc metabolism and related diseases.
PubMed:Zinc lozenges as cure for the common cold--a review and hypothesis.
PubMed:Effect of prenatal zinc supplementation on birthweight.
PubMed:Zicam-induced damage to mouse and human nasal tissue.
PubMed:Dietary management of hepatic copper accumulation in Labrador Retrievers.
PubMed:High sensitive determination of zinc with novel water-soluble small molecular fluorescent sensor.
PubMed:[Hidradenitis suppurativa].
PubMed:Use of zinc supplements to reduce upper respiratory infections in United States Air Force Academy cadets.
PubMed:Identification and characterization of Gluconacetobacter diazotrophicus mutants defective in the solubilization of phosphorus and zinc.
PubMed:Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells.
PubMed:Effect of zinc supplementation on the antioxidant, copper, and iron status of physically active adolescents.
PubMed:Zinc supplementation does not alter plasma homocysteine, vitamin B12 and red blood cell folate concentrations in French elderly subjects.
PubMed:Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa.
PubMed:Evaluation of efficacy and safety of zinc gluconate associated with dimethyl sulphoxide for sexually mature canine males chemical neutering.
PubMed:No antioxidant beneficial effect of zinc supplementation on oxidative stress markers and antioxidant defenses in middle-aged and elderly subjects: the Zenith study.
PubMed:Antiplaque/antigingivitis efficacy and safety of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel. Results of a 6-month clinical trial.
PubMed:Burn-induced oxidative stress is altered by a low zinc status: kinetic study in burned rats fed a low zinc diet.
PubMed:Toxic effects of iterative intraperitoneal administration of zinc gluconate in rats.
PubMed:Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.
PubMed:Oral malodor reduction by a palatal mucoadhesive tablet containing herbal formulation.
PubMed:[Acne, pregnant women and zinc salts: a literature review].
PubMed:Do zinc and selenium prevent the antioxidant, hepatic and renal system impairment caused by aspirin in rats?
PubMed:A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers.
PubMed:A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea.
PubMed:Therapeutic effectiveness of ionic zinc for common colds.
PubMed:Comparison of intratesticular injection of zinc gluconate versus surgical castration to sterilize male dogs.
PubMed:Glycemic control of type 2 diabetic patients after short-term zinc supplementation.
PubMed:Zinc metal solubilization by Gluconacetobacter diazotrophicus and induction of pleomorphic cells.
PubMed:Transient symptomatic zinc deficiency in a breast-fed preterm infant.
PubMed:Clinical evaluation of the bioavailability of zinc-enriched yeast and zinc gluconate in healthy volunteers.
PubMed:Anticalculus effect of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel: results of a randomized, double-blind, controlled clinical trial.
PubMed:Effect of zinc added to multi-vitamin supplementation containing low-dose vitamin A on plasma retinol level in children--a double-blind randomized, controlled trial.
PubMed:Intratesticular injection of a zinc-based solution as a contraceptive for dogs.
PubMed:Effect of zinc supplementation on thyroid hormone function. A case study of two college females.
PubMed:Hidradenitis suppurativa and zinc: a new therapeutic approach. A pilot study.
PubMed:Olfaction and olfactory epithelium in mice treated with zinc gluconate.
PubMed:The effects of sugar-free chewing gums on dental plaque regrowth: a comparative study.
PubMed:Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress.
PubMed:Double-blind, placebo-controlled trial comparing effects of supplementation of two micronutrient sprinkles on fatty acid status in Cambodian infants.
PubMed:[Erosive pustular dermatosis of the leg: role of zinc deficiency?].
PubMed:Oral zinc augmentation with vitamins A and D increases plasma zinc concentration: implications for burden of disease.
PubMed:Supplementation with a complex of active nutrients improved dermal and epidermal characteristics in skin equivalents generated from fibroblasts from young or aged donors.
PubMed:Zinc-deficiency dermatitis in breast-fed infants.
PubMed:Solubilization of zinc compounds by the diazotrophic, plant growth promoting bacterium Gluconacetobacter diazotrophicus.
PubMed:Re: Alexander TH, Davidson TM. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. Laryngoscope 2006;116:217-220.
PubMed:RE: Alexander TH, Davidson TM. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. Laryngoscope 2006;116:217-220.
PubMed:The effects of zinc on the olfactory neuroepithelium and olfactory bulbs of the Sprague-Dawley rat after oral administration of zinc-gluconate trihydrate.
PubMed:Multiple exposures to chlorhexidine and xylitol: adhesion and biofilm formation by Streptococcus mutans.
PubMed:Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: a cluster-randomised trial.
PubMed:[Clinical observation on chiropractics combined with acupuncture at Sifeng (EX-UE 10) for treatment of infantile anorexia].
PubMed:Micronutrients (including zinc) reduce diarrhoea in children: the Pakistan Sprinkles Diarrhoea Study.
PubMed:Demonstrating zinc and iron bioavailability from intrinsically labeled microencapsulated ferrous fumarate and zinc gluconate Sprinkles in young children.
PubMed:Intranasal zinc and anosmia: the zinc-induced anosmia syndrome.
PubMed:Ineffectiveness of zinc gluconate nasal spray and zinc orotate lozenges in common-cold treatment: a double-blind, placebo-controlled clinical trial.
PubMed:The pharmacokinetics of zinc from zinc gluconate: a comparison with zinc oxide in healthy men.
PubMed:Safety of zinc gluconate glycine (Cold-Eeze) in a geriatric population: a randomized, placebo-controlled, double-blind trial.
PubMed:Chronic zinc toxicity in an infant who received zinc therapy for atopic dermatitis.
PubMed:Intratesticular injection of a balanced zinc solution for permanent sterilization of dogs.
PubMed:Nutritional and technological behavior of stabilized iron-gluconate in wheat flour.
PubMed:[Erosive pustulosis of the scalp: 3 cases].
PubMed:[Observation on clinical efficacy of combined therapy of zinc supplement and jinye baidu granule in treating human cytomegalovirus infection].
PubMed:Normal growth rate in rats is recovered after a period of zinc deficiency by restoration of zinc supply by means of a zinc-fortified Petit Suisse cheese.
PubMed:Determination of relative bioavailability of zinc in a petit suisse cheese using weight gain and bone zinc content in rats as markers.
PubMed:[Assessment of the photosensitization potential of zinc gluconate].
PubMed:Effect of zinc gluconate on propionibacterium acnes resistance to erythromycin in patients with inflammatory acne: in vitro and in vivo study.
PubMed:The effect of zinc supplementation on the treatment of chronic hepatitis C patients with interferon and ribavirin.
PubMed:Treatment of acute lymphocytic leukemia using zinc adjuvant with chemotherapy and radiation--a case history and hypothesis.
PubMed:Some properties of two aldolases in extracts of Aspergillus oryzae.
PubMed:Efficacy of boric-complexed zinc and acetic-complexed zinc otic preparations for canine yeast otitis externa.
PubMed:Zinc gluconate in the treatment of dysgeusia--a randomized clinical trial.
PubMed:Zinc lozenges: cold cure or candy? Solution chemistry determinations.
PubMed:Efficacy of zinc against common cold viruses: an overview.
PubMed:Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.
PubMed:Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats.
PubMed:Anosmia after intranasal zinc gluconate use.
PubMed:[Pathogenesis and treatment of Wilson's disease].
PubMed:[Zinc salts in dermatology].
PubMed:Investigation of lymphocyte gene expression for use as biomarkers for zinc status in humans.
PubMed:[Lithium].
PubMed:FDA approves first injectable solution for dog sterilization.
PubMed:Simultaneous separation of nine metal ions and ammonium with nonaqueous capillary electrophoresis.
PubMed:An open-label, single-center, phase IV clinical study of the effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) in reducing the duration and symptoms of the common cold in school-aged subjects.
PubMed:Effects of oral zinc supplementation on serum leptin levels in Ache males of eastern Paraguay.
PubMed:Cold-Eeze lozenge for common colds.
PubMed:Copper deficiency anemia and nephrosis in zinc-toxicity: a case report.
PubMed:Effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) against the common cold in school-aged subjects: a retrospective chart review.
PubMed:Solubilization of zinc salts by a bacterium isolated from the air environment of a tannery.
PubMed:Toxic effects associated with consumption of zinc.
PubMed:Supplemental zinc lowers measures of iron status in young women with low iron reserves.
PubMed:The significance of the source of zinc and its anti-VSC effect.
PubMed:Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children.
PubMed:Evaluation of the efficacy of intranasal zinc gluconate.
PubMed:Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds.
PubMed:Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris.
PubMed:Sugar-free zinc gluconate glycine lozenges (Cold-Eeze) do not adversely affect glucose control in patients with type 1 or type 2 diabetes mellitus.
PubMed:In vitro effects of zinc gluconate and acetate on red cell aggregability.
PubMed:Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds.
PubMed:Bioavailability, biodistribution, and toxicity of BioZn-AAS(1): a new zinc source. comparative studies in rats.
PubMed:Efficacy and safety study of two zinc gluconate regimens in the treatment of inflammatory acne.
PubMed:[Influence of insufficient zinc on immune functions in NIDDM patients].
PubMed:Zinc and the common cold: a meta-analysis revisited.
PubMed:Zinc salts inactivate clinical isolates of herpes simplex virus in vitro.
PubMed:[Systemic treatment of acne: recommendations. The French Agency of Sanitary Safety of Health Products].
PubMed:[Systemic treatment of acne: proposal. The French Agency of Sanitary Safety of Health Products].
PubMed:Zinc.
PubMed:Short- and long-term uses of calcium acetate do not change hair and serum zinc concentrations in hemodialysis patients.
PubMed:In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese.
PubMed:Treatment for iron deficiency anaemia with a combined supplementation of iron, vitamin A and zinc in women of Dinajpur, Bangladesh.
PubMed:Glycine antagonist and NO synthase inhibitor protect the developing mouse brain against neonatal excitotoxic lesions.
PubMed:Zinc lozenges for treating the common cold in children.
PubMed:Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
PubMed:Zinc gluconate lozenges for treating the common cold in children: a randomized controlled trial.
PubMed:Zinc gluconate and the common cold. Review of randomized controlled trials.
PubMed:Comparative study of the in vitro inflammatory activity of three nickel salts on keratinocytes.
PubMed:[Hepatitis in dogs; a review].
PubMed:Zinc gluconate: acute ingestion.
PubMed:The role of zinc lozenges in treatment of the common cold.
PubMed:Protective effects of zinc salts on TPA-induced hepatic and brain lipid peroxidation, glutathione depletion, DNA damage and peritoneal macrophage activation in mice.
PubMed:Where's the bias?
PubMed:Zinc-induced suppression of inflammation in the respiratory tract, caused by infection with human rhinovirus and other irritants.
PubMed:Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea--a community-based, double-blind, controlled trial.
PubMed:Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children.
PubMed:Zinc: the missing link?
PubMed:Protective effect of zinc gluconate on chemically induced gastric ulcer.
PubMed:Competitive reverse transcriptase-polymerase chain reaction shows that dietary zinc supplementation in humans increases monocyte metallothionein mRNA levels.
PubMed:Zinc gluconate lozenges for treating the common cold.
PubMed:Zinc gluconate lozenges for treating the common cold.
PubMed:Zinc gluconate lozenges for treating the common cold.
PubMed:Zinc gluconate lozenges for treating the common cold.
PubMed:Zinc lozenges reduce the duration of common cold symptoms.
PubMed:Zinc for the common cold.
PubMed:Effects of zinc gluconate on nephrotoxicity and glutathione metabolism disorder induced by cis-platin in mice.
PubMed:Comparative in vitro oxygen radical scavenging ability of zinc methionine and selected zinc salts and antioxidants.
PubMed:Effect of zinc supplementation on observed activity in low socioeconomic Indian preschool children.
PubMed:Zinc for treating the common cold: review of all clinical trials since 1984.
PubMed:Zinc lozenges as cure for common colds.
PubMed:Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study.
PubMed:Zinc status and serum testosterone levels of healthy adults.
PubMed:Zinc acetate and lyophilized aloe barbadensis as vaginal contraceptive.
PubMed:Production of gluconic acid using Micrococcus sp.: optimisation of carbon and nitrogen sources.
PubMed:Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels.
PubMed:Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation.
PubMed:Effects of oral zinc gluconate on glucose effectiveness and insulin sensitivity in humans.
PubMed:In vitro influence of zinc and magnesium on the deformability of red blood cells artificially hardened by heating.
PubMed:Effects of zinc supplementation on the phagocytic functions of polymorphonuclears in patients with inflammatory rheumatic diseases.
PubMed:Zinc salts for the treatment of olfactory and gustatory symptoms in psychiatric patients: a case series.
PubMed:Controlled trial of zinc supplementation in anorexia nervosa.
PubMed:Reactive oxygen species produced in metal-catalyzed oxidation of bis(trifluoromethyl)disulfide and protection by ZE.
PubMed:Zinc arginine, a 5 alpha-reductase inhibitor, reduces rat ventral prostate weight and DNA without affecting testicular function.
PubMed:Reversal of selenium and zinc deficiencies in chronic hemodialysis patients by intravenous sodium selenite and zinc gluconate supplementation. Time-course of glutathione peroxidase repletion and lipid peroxidation decrease.
PubMed:[Some factors influencing the bioavailability of zinc in oral pharmaceutical dosage forms].
PubMed:Zinc salts effects on granulocyte zinc concentration and chemotaxis in acne patients.
PubMed:Zinc-induced copper deficiency in an infant.
PubMed:Zinc deficiency in a full-term breast-fed infant: unusual presentation.
PubMed:Zinc gluconate and the common cold: a controlled clinical study.
PubMed:Zinc(II) in saliva: determination of concentrations produced by different formulations of zinc gluconate lozenges containing common excipients.
PubMed:Absorption and metabolism of oral zinc gluconate in humans in fasting state, during, and after a meal.
PubMed:The role of the sodium pump in the plasma membrane potential changes during mast cell activation.
PubMed:Effects of zinc gluconate and nedocromil sodium on performance deficits produced by the common cold.
PubMed:A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder.
PubMed:Zinc gluconate lozenges for common cold. A double-blind clinical trial.
PubMed:The sensitivity to Zn2+ discriminates between typical and atypical mast cells.
PubMed:[Cutaneous manifestations of zinc deficiency in Crohn disease].
PubMed:Zinc in mononuclear leucocytes in alcoholics with liver cirrhosis or chronic pancreatitis and in patients with Crohn's disease before and after zinc supplementation.
PubMed:Adolescent pregnancy: associations among body weight, zinc nutriture, and pregnancy outcome.
PubMed:Effect of zinc on the immune status of zinc-depleted AIDS related complex patients.
PubMed:Failure of zinc gluconate in treatment of acute upper respiratory tract infections.
PubMed:Infection and immunity in Down syndrome: a trial of long-term low oral doses of zinc.
PubMed:Can neo-adjuvant chemotherapy prevent residual tumors?
PubMed:Low doses of zinc gluconate for inflammatory acne.
PubMed:Retinal toxicity of intravitreal ethyldeoxyuridine and zinc.
PubMed:Kinetic regulation of hexokinase activity in a heterogeneous branched bienzyme system.
PubMed:Stability constants of zinc complexes affect common cold treatment results.
PubMed:Zinc for the common cold.
PubMed:Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges.
PubMed:Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds.
PubMed:Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans.
PubMed:The problems of taste in placebo matching: an evaluation of zinc gluconate for the common cold.
PubMed:From experimental to clinical attempts in immunorestoration with bestatin and zinc.
PubMed:A phase II trial of immunorestoration with zinc gluconate in immunodepressed cancer patients.
PubMed:Zinc may play a role in the regulation of thyrotropin function.
PubMed:Trace elements in hair in the UK: results and interpretation in the preconception situation.
PubMed:Zinc concentration and survival in rats infected with Salmonella typhimurium.
PubMed:The effects of zinc gluconate, vitamin A and caesium salts on colon carcinoma in mice.
PubMed:The response of colon carcinoma in mice to cesium, zinc and vitamin A.
PubMed:Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study.
PubMed:Variations in cutaneous zinc concentrations after oral administration of zinc gluconate.
PubMed:The influence of orally-administered vitamin C or zinc on the absorption of and the biological response to lead.
PubMed:Gluconate zinc in acrodermatitis enteropathica.
PubMed:The influence of zinc gluconate and casein hydrolysate on the fluid and tissue kinetics of zinc-65 in the baboon prostate.
 
Notes:
Dietary zinc supplement
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