EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

glyceryl thioglycolate
mercaptoacetic acid, monoester with 1,2,3-propanetriol

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CAS Number: 30618-84-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:250-264-8
Nikkaji Web:J1.237.846G
XlogP3:-0.70 (est)
Molecular Weight:166.19650000
Formula:C5 H10 O4 S
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 351.28 °C. @ 760.00 mm Hg (est)
Flash Point: 331.00 °F. TCC ( 166.30 °C. ) (est)
logP (o/w): -0.799 (est)
Soluble in:
 water, 8.222e+005 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair straightening agents
hair waving agents
BOC Sciences
For experimental / research use only.
Glyceryl monothioglycolate 95%
Glyceryl Thioglycolate
Odor: characteristic
Use: Glyceryl Thioglycolate's unique reducing properties of the SH-group opens the sulfur bridges in the ceratine structure of the hair. If this is done when the hair is wrapped around hair rollers, the hair structure is weakened. After rinsing in a second step the sulfur bridges are reconnected with an oxidizing chemical like hydrogenperoxide and the hair fibre gets its desired curled shape. The properties of Glyceryl Thioglycolate allow its use in hair perms as well as in hair straighteners.
For experimental / research use only.
glyceryl monothioglycolate, Technical grade
Santa Cruz Biotechnology
For experimental / research use only.
Glyceryl monothioglycolate, Technical grade
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for glyceryl thioglycolate usage levels up to:
 not for fragrance use.
Recommendation for glyceryl thioglycolate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):30618-84-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :3034372
National Institute of Allergy and Infectious Diseases:Data
2,3-dihydroxypropyl 2-sulfanylacetate
 2,3-dihydroxypropyl 2-sulfanylacetate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:30618-84-9
Pubchem (cid):3034372
Pubchem (sid):135048896
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Potential Blenders and core components note
None Found
Potential Uses:
 depilating agents
 reducing agents
Occurrence (nature, food, other):note
 not found in nature
 acetic acid, 2-mercapto-, 2,3-dihydroxypropyl ester
 acetic acid, mercapto-, monoester with 1,2,3-propanetriol
 acetic acid, mercapto-, monoester with glycerol
2,3-dihydroxypropyl 2-sulfanylacetate
2,3-dihydroxypropyl sulfanylacetate
 glyceryl monothioglycolate
 mercaptoacetic acid, monoester with 1,2,3-propanetriol
 mercaptoacetic acid, monoester with propane-1,2,3-triol


PubMed:North American Contact Dermatitis Group patch test results: 2009 to 2010.
PubMed:Occupational contact dermatitis in hairdressers/cosmetologists: retrospective analysis of north american contact dermatitis group data, 1994 to 2010.
PubMed:Occupational contact allergens: are they also associated with occupational asthma?
PubMed:Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid.
PubMed:Permanent-wave dermatitis: contact allergy to cysteamine hydrochloride.
PubMed:Type I and type IV immune responses to glyceryl thioglycolate.
PubMed:Dermatitis in hairdressers. (I). The experience of the past 4 years.
PubMed:[Glycerol monothioglycolate eczema in a hairdresser. Persistence of the allergen in the hair several weeks after the application of a permanent].
PubMed:The patch test dilution of glyceryl thioglycolate.
None found
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