asiaticoside
emdecassol
 
Notes:
Constit. of Centella asiatica (Asiatic pennywort)
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CAS Number: 16830-15-2Picture of molecule
ECHA EINECS - REACH Pre-Reg: 240-851-7
FDA UNII: PKO39VY215
Beilstein Number: 0078195
MDL: MFCD06642601
XlogP3-AA: 0.10 (est)
Molecular Weight: 959.13446000
Formula: C48 H78 O19
BioActivity Summary: listing
Category: antioxidants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 1000.00 °C. @ 760.00 mm Hg (est)
Flash Point: 551.00 °F. TCC ( 288.20 °C. ) (est)
logP (o/w): 0.089 (est)
Soluble in:
 water, 1.132 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
perfuming agents
skin conditioning
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Suppliers:
Changsha Organic Herb
Centella asiatica Extract
ExtraSynthese
For experimental / research use only.
Asiaticoside (HPLC) ≥99%
Santa Cruz Biotechnology
For experimental / research use only.
Asiaticoside ≥98%
Sigma-Aldrich
For experimental / research use only.
Asiaticoside
analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants
Recommendation for asiaticoside usage levels up to:
 not for fragrance use.
 
Recommendation for asiaticoside flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 108062
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0016830152
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References:
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 108062
Pubchem (sid): 135065643
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
KEGG (GenomeNet): C15428
HMDB (The Human Metabolome Database): HMDB36656
FooDB: FDB015582
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 additives 
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Occurrence (nature, food, other): note
 pennywort asiatic pennywort
Search Trop  Picture
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Synonyms:
 asiaticosid
 blastoestimulina
 centelase
 dermatologico
 emdecassol
 madecassol
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Articles:
Google Patents: Derivatives of asiaticoside and their process of preparation
PubMed: Asiaticoside Inhibits TNF-α-Induced Endothelial Hyperpermeability of Human Aortic Endothelial Cells.
PubMed: The potential of asiaticoside for TGF-β1/Smad signaling inhibition in prevention and progression of hypoxia-induced pulmonary hypertension.
PubMed: Asiaticoside attenuates the effects of spinal cord injury through antioxidant and anti‑inflammatory effects, and inhibition of the p38‑MAPK mechanism.
PubMed: Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons.
PubMed: Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice.
PubMed: Chitosan-aluminum monostearate composite sponge dressing containing asiaticoside for wound healing and angiogenesis promotion in chronic wound.
PubMed: Medicinal value of asiaticoside for Alzheimer's disease as assessed using single-molecule-detection fluorescence correlation spectroscopy, laser-scanning microscopy, transmission electron microscopy, and in silico docking.
PubMed: Asiaticoside attenuates diabetes-induced cognition deficits by regulating PI3K/Akt/NF-κB pathway.
PubMed: Neuroprotective effects of Asiaticoside.
PubMed: Study of the cytotoxicity of asiaticoside on rats and tumour cells.
PubMed: Production of asiaticoside from centella (Centella asiatica L. Urban) cells in bioreactor.
PubMed: Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy.
PubMed: Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma.
PubMed: [Biochemical regulatory mechanism of asiaticoside in preventing and treating stent restenosis].
PubMed: Asiaticoside induces type I collagen synthesis and osteogenic differentiation in human periodontal ligament cells.
PubMed: [Effect of algorithms for calibration set selection on quantitatively determining asiaticoside content in Centella total glucosides by near infrared spectroscopy].
PubMed: Combination treatment with asiaticoside and rapamycin: A new hope for in-stent restenosis.
PubMed: Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism.
PubMed: Asiaticoside attenuates lipopolysaccharide-induced acute lung injury via down-regulation of NF-κB signaling pathway.
PubMed: Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model.
PubMed: [Analysis on preparation and characterization of asiaticoside-loaded flexible nanoliposomes].
PubMed: Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles.
PubMed: Asiaticoside, a trisaccaride triterpene induces biochemical and molecular variations in brain of mice with parkinsonism.
PubMed: Growth and asiaticoside production in multiple shoot cultures of a medicinal herb, Centella asiatica (L.) Urban, under the influence of nutrient manipulations.
PubMed: Antipyretic and anti-inflammatory effects of asiaticoside in lipopolysaccharide-treated rat through up-regulation of heme oxygenase-1.
PubMed: Prophylactic effects of asiaticoside-based standardized extract of Centella asiatica (L.) Urban leaves on experimental migraine: Involvement of 5HT1A/1B receptors.
PubMed: Effect of Agrobacterium rhizogenes and elicitation on the asiaticoside production in cell cultures of Centella asiatica.
PubMed: [Simultaneous determination of madecassoside, asiaticoside and their aglycones in Centella asiatica (L.) urban extracts by RP-HPLC].
PubMed: Asiaticoside: attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax.
PubMed: Effect of asiaticoside on 99mTc-tetrofosmin and 99mTc-sestamibi uptake in MCF-7 cells.
PubMed: Anti-diabetic effect of a combination of andrographolide-enriched extract of Andrographis paniculata (Burm f.) Nees and asiaticoside-enriched extract of Centella asiatica L. in high fructose-fat fed rats.
PubMed: Asiaticoside induces tumour-necrosis-factor-α-mediated nitric oxide production to cure experimental visceral leishmaniasis caused by antimony-susceptible and -resistant Leishmania donovani strains.
PubMed: A rapid one-step immunochromatographic assay for the detection of asiaticoside.
PubMed: Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts.
PubMed: Beneficial effects of asiaticoside on cognitive deficits in senescence-accelerated mice.
PubMed: In vitro inhibitory effects of asiaticoside and madecassoside on human cytochrome P450.
PubMed: Induction of root colonization by Piriformospora indica leads to enhanced asiaticoside production in Centella asiatica.
PubMed: [The cellular and molecular mechanism of inhibitory effect of asiaticoside on capsular contracture following breast augmentation].
PubMed: Isolation and identification of an anti-hepatitis B virus compound from Hydrocotyle sibthorpioides Lam.
PubMed: Protective effects of asiaticoside on septic lung injury in mice.
PubMed: [Protective effects of asiaticoside on sepsis-induced acute kidney injury in mice].
PubMed: Preparation of a specific monoclonal antibody to asiaticoside for the development of an enzyme-linked immunosorbent assay.
PubMed: In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin.
PubMed: Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice.
PubMed: Effect of asiaticoside on hypertrophic scar in the rabbit ear model.
PubMed: [Effect of asiaticoside on the expression of transforming growth factor-beta mRNA and matrix metalloproteinases in hypertrophic scars].
PubMed: [Asiaticoside inducing apoptosis of tumor cells and enhancing anti-tumor activity of vincristine].
PubMed: Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism.
PubMed: Effects of asiaticoside on the expression of Smad protein by normal skin fibroblasts and hypertrophic scar fibroblasts.
PubMed: Asiaticoside induces human collagen I synthesis through TGFbeta receptor I kinase (TbetaRI kinase)-independent Smad signaling.
PubMed: Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system.
PubMed: Stimulation of asiaticoside accumulation in the whole plant cultures of Centella asiatica (L.) urban by elicitors.
PubMed: [Effects of Asiaticoside on hypertrophic scars in a nude mice model].
PubMed: Anxiolytic-like effect of asiaticoside in mice.
PubMed: [Effects of asiaticoside on cell proliferation and Smad signal pathway of hypertrophic scar fibroblasts].
PubMed: Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins.
PubMed: Antidepressant-like effect of asiaticoside in mice.
PubMed: In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica.
PubMed: [Near-infrared spectroscopy technology for online monitoring of the column separation and purification process of active components of Centella asiatica L. Urban].
PubMed: [Preparation of asiaticoside and madecassoside from the extract of Centella asiatica (L.) Urb using preparative high performance liquid chromatography].
PubMed: Enhanced production of asiaticoside from hairy root cultures of Centella asiatica (L.) Urban elicited by methyl jasmonate.
PubMed: Dermal fibroblast-associated gene induction by asiaticoside shown in vitro by DNA microarray analysis.
PubMed: Column-switching high-performance liquid chromatographic assay for determination of asiaticoside in rat plasma and bile with ultraviolet absorbance detection.
PubMed: Asiaticoside-induced elevation of antioxidant levels in healing wounds.
PubMed: [Comparative activity of asiaticoside and madecassoside on type I and III collagen synthesis by cultured human fibroblasts].
PubMed: Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts.
PubMed: Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract of Centella asiatica.
PubMed: Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models.
PubMed: Evaluation of transdermal delivery of nanoemulsions in ex vivo porcine skin using two-photon microscopy and confocal laser-scanning microscopy.
PubMed: Evaluation of the effects of a preparation containing asiaticoside on periocular wrinkles of human volunteers.
PubMed: Cloning of a cDNA probably encoding oxidosqualene cyclase associated with asiaticoside biosynthesis from Centella asiatica (L.) Urban.
PubMed: Influence of asiatic acid, madecassic acid, and asiaticoside on human collagen I synthesis.
PubMed: [Effects of asiaticoside on the balance of inflammatory factors of mouse's acute lung injury induced by LPS].
PubMed: Protective effects of asiaticoside derivatives against beta-amyloid neurotoxicity.
PubMed: Chemical constitution of asiaticoside.
PubMed: Electrospun gelatin fiber mats containing a herbal-Centella asiatica-extract and release characteristic of asiaticoside.
PubMed: Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats.
PubMed: The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.
PubMed: Separation mechanism of oleanane and ursane pentacyclic triterpenoid isomers by coordination chromatography.
PubMed: Metabolomic analysis of methyl jasmonate-induced triterpenoid production in the medicinal herb Centella asiatica (L.) urban.
PubMed: Formulation, standardization and pharmacological studies of Saraswataristam: a polyhedral preparation.
PubMed: Centella asiatica in dermatology: an overview.
PubMed: [First tests on the action of asiaticoside on lupus erythematosus and certain lesions produced by the bacilli of Koch and Hansen].
PubMed: Identification of Major Active Ingredients Responsible for Burn Wound Healing of Centella asiatica Herbs.
PubMed: A trial of asiaticoside on skin graft donor areas.
PubMed: [Action of a pentacyclic triterpenoid, asiaticoside, isolated from Hydrocotyle masagascariensis or Centella asiatica, against gastric ulceration in the Wistar rat exposed to cold at 2 degrees C].
PubMed: Biochemistry of the effects of asiaticoside on human polymorphonuclear leukocytes.
PubMed: Studies on the mechanism of action of asiaticoside (Madecassol) on experimental granulation tissue and cultured fibroblasts and its clinical application in systemic scleroderma.
PubMed: The metabolism of asiatic acid,-madecassic acid and asiaticoside in the rat.
PubMed: [Contact allergy to asiaticoside. Preliminary note].
PubMed: [The use of asiaticoside in the repair of losses of substance and the subsequent covering with autoplastic grafts].
PubMed: The effect of asiaticoside on guinea pig skin.
PubMed: Effect of asiaticoside on wound healing in the rat.
PubMed: [Asiaticoside and cicatrization of episiotomies].
PubMed: [THE USE OF ASIATICOSIDE IN TRAUMATOLOGY].
PubMed: [ASIATICOSIDE AS A CICATRIZING AGENT IN ULCERATIONS].
PubMed: [ANTHRONE DETERMINATION OF THE ASIATICOSIDE ISOLATED FROM CENTELLA ASIATICA BY QUANTITATIVE CHROMATOGRAPHY ON THIN LAYERS OF GLASS POWDER].
PubMed: [Healing activity of asiaticoside in obstetrical injuries of the perineum].
PubMed: [Use of asiaticoside in the treatment of bedsores].
PubMed: [Some observations on the use of asiaticoside (Madecassol) in general surgery].
PubMed: Treatment of keloid with asiaticoside.
PubMed: [Clinical results of an asiaticoside in cutaneous ulcerous lesions].
PubMed: [The therapeutic action of asiaticoside in colposcopically diagnosed ectopias].
PubMed: [Asiaticoside and experimental fractures].
PubMed: [On the action of asiaticoside in experimental gastric lesions induced by phenylchinolincarbonic acid].
PubMed: [The therapeutic action of asiaticoside in the dermatological field].
PubMed: [Asiaticoside in the treatment of ulcers in lepers].
PubMed: Drug interaction between asiaticoside and some anti-inflammatory drugs in wound healing of the rat.
PubMed: Treatment of ulcer bladder with asiaticoside.
PubMed: Local asiaticoside in the treatment of ulcers & wounds of the cornea.
PubMed: [Action of asiaticoside (pentacyclic triterpene) extracted from Hydrocotyle madagascariensis on duodenal ulcers induced with mercaptoethylamine in male Wistar rats].
PubMed: Reticuloses and epidermal tumors in hairless mice after topical skin applications of cantharidin and asiaticoside.
PubMed: The effect of asiaticoside on pig skin in organ culture.
PubMed: The morphological and pharmacological effects of asiaticoside upon skin in vitro and in vivo.
PubMed: Effect of asiaticoside (Madecassol) on the healing process in cataract surgical wounds and retinal detachment operations (clinical and experimental study).
PubMed: [Oxygen dressings and asiaticoside in the treatment of burns].
PubMed: [CLINICAL CONTRIBUTION ON THE USE OF ASIATICOSIDE IN UROLOGIC DISEASES].
PubMed: [CUTANEOUS ENZYMATIC ACTIVITY IN THE PROCESSES OF REGENERATION. I. EFFECT OF ASIATICOSIDE ON LEUCINE AMINOPEPTIDASE (LAP) AND THE SULFHYDRYL GROUPS IN NORMAL SUBJECTS].
PubMed: [Perineal lesions and asiaticoside].
PubMed: [Anthrone determination of asiaticoside, ester-oside of Centella asiatica].
PubMed: [The use of asiaticoside in ulcerative corneal diseases].
PubMed: [Asiaticoside in the therapy of cervical lesions of non-neoplastic nature].
PubMed: [Effect of asiaticoside on the plasma level and urinary elimination of amino acids].
PubMed: [Use of asiaticoside in radiotherapy].
PubMed: [Treatment of stubborn ulcers of the lower extremities with Asiaticoside (Centella asiatica)].
PubMed: [On the use in pathological corneal ulcerations of a new general cicatrizant: asiaticoside or madecassol L.N].
PubMed: [Research on the hormonal action of a triterpene of the amyrine series (asiaticoside)].
PubMed: [Asiaticoside; active constituent of Centella asiatica, initiating agent of the new growth in the early stage of cicatrization of skin ulcers].
PubMed: [Asiaticoside extracted from Centella asiatica and its therapeutic uses in cicatrization of experimental and refractory wounds (leprosy, cutaneous tuberculosis and lupus)].
PubMed: [Chemical constitution of asiaticoside and especially of asiatic acid. VI. Inclusion of asiatic acid in the alpha-amyrine series].
PubMed: Production of polyclonal antibody against madecassoside and development of immunoassay methods for analysis of triterpene glycosides in Centella asiatica.
PubMed: Seasonal Variation of Triterpenes and Phenolic Compounds in Australian Centella asiatica (L.) Urb.
PubMed: Factors affecting the content of pentacyclic triterpenes in Centella asiatica raw materials.
PubMed: Protective effect of centella triterpene saponins against cyclophosphamide-induced immune and hepatic system dysfunction in rats: its possible mechanisms of action.
PubMed: A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-α in activated RAW 264.7 cells.
PubMed: Synthesis and evaluation of asiatic acid derivatives as anti-fibrotic agents: structure/activity studies.
PubMed: Molecular signalings in keloid disease and current therapeutic approaches from natural based compounds.
PubMed: Centelloside accumulation in leaves of Centella asiatica is determined by resource partitioning between primary and secondary metabolism while influenced by supply levels of either nitrogen, phosphorus or potassium.
PubMed: Potential role of natural compounds against skin aging.
PubMed: In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity.
PubMed: Tocotrienol-rich fraction, [6]-gingerol and epigallocatechin gallate inhibit proliferation and induce apoptosis of glioma cancer cells.
PubMed: Medicinal plants and their natural components as future drugs for the treatment of burn wounds: an integrative review.
PubMed: Separation rule of oleanane and ursane pentacyclic triterpenoids isomers from nature plants by coordination chromatography.
PubMed: Morphological, chemical and molecular characterization of Centella asiatica germplasms for commercial cultivation in the Indo-Gangetic plains.
PubMed: Anxiolytic effects of standardized extract of Centella asiatica (ECa 233) after chronic immobilization stress in mice.
PubMed: Formulation, standardization and pharmacological studies of Saraswataristam: a polyhedral preparation.
PubMed: New 9, 19-cycloartane triterpenoid from the root of Cimicifuga foetida.
PubMed: Glycoside-bearing liposomal delivery systems against macrophage-associated disorders involving Mycobacterium leprae and Mycobacterium tuberculosis.
PubMed: In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.
PubMed: Triterpenoid saponins from the stem barks of Schefflera heptaphylla.
PubMed: [Inhibitiory action of asiaiticoside on collagen-induced arthritis in mice].
PubMed: Discrimination of three Pegaga (Centella) varieties and determination of growth-lighting effects on metabolites content based on the chemometry of 1H nuclear magnetic resonance spectroscopy.
PubMed: The comparative steady-state bioavailability of the active ingredients of Madecassol.
PubMed: Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats.
PubMed: Centella asiatica in cosmetology.
PubMed: Two new triterpene glycosides from Centella asiatica.
PubMed: Titrated extract of Centella asiatica provides a UVB protective effect by altering microRNA expression profiles in human dermal fibroblasts.
PubMed: Antipsoriatic activity and cytotoxicity of ethanolic extract of Nigella sativa seeds.
PubMed: Cytotoxic cycloartane triterpene saponins from Actaea asiatica.
PubMed: An improved HPLC-UV method for the simultaneous quantification of triterpenic glycosides and aglycones in leaves of Centella asiatica (L.) Urb (APIACEAE).
PubMed: Wound healing activities of different extracts of Centella asiatica in incision and burn wound models: an experimental animal study.
PubMed: Inhibition of cPLA2 and sPLA2 activities in primary cultures of rat cortical neurons by Centella asiatica water extract.
PubMed: Triterpene composition and bioactivities of Centella asiatica.
PubMed: The influence of certain taxonomic and environmental parameters on biomass production and triterpenoid content in the leaves of Centella asiatica (L.) Urb. from Madagascar.
PubMed: Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase.
PubMed: Bioactive compounds from natural resources against skin aging.
PubMed: Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways.
PubMed: Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection.
PubMed: [Determination of aisaticoside in Centella asiatica extract by HPLC-ELSD].
PubMed: Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.
PubMed: Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam.
PubMed: Interesting linkage between wound healing and hepatoprotective activities.
PubMed: Wound healing acceleration effect of endemic Ononis species growing in Turkey.
PubMed: Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models.
PubMed: [Studies on fingerprints of Centella asiatica by HPLC].
PubMed: The efficacy and side effects of oral Centella asiatica extract for wound healing promotion in diabetic wound patients.
PubMed: Triterpenoids and their glycosides from the bark of Schefflera octophylla.
PubMed: Targeting of plant glycoside-bearing liposomes to specific cellular and subcellular sites.
PubMed: An ethnopharmacological study on Verbascum species: from conventional wound healing use to scientific verification.
PubMed: New alternative therapy for orofacial localized scleroderma.
PubMed: Centella asiatica water extract inhibits iPLA2 and cPLA2 activities in rat cerebellum.
PubMed: Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside.
PubMed: Effect of virgin fatty oil of Pistacia lentiscus on experimental burn wound's healing in rabbits.
PubMed: New innovations in scar management.
PubMed: In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins.
PubMed: Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica.
PubMed: Contact dermatitis due to madecassol.
PubMed: Contact dermatitis due to Centella asiatica.
PubMed: Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban.
PubMed: Comparative analysis of active constituents in Centella asiatica samples from Madagascar: application for ex situ conservation and clonal propagation.
PubMed: Structure-related cytotoxicity and anti-hepatofibric effect of asiatic acid derivatives in rat hepatic stellate cell-line, HSC-T6.
PubMed: [Cycloartane triterpenoid of Cimicifuga foetida].
PubMed: Improving lip wrinkles: lipstick-related image analysis.
PubMed: An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products.
PubMed: Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka.
PubMed: In vitro experiments with Centella asiatica: investigation to elucidate the effect of an indigenously prepared powder of this plant on the acid-fastness and viability of M. tuberculosis.
PubMed: Type I pro-collagen promoting and anti-collagenase activities of Phyllanthus emblica extract in mouse fibroblasts.
PubMed: Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models.
PubMed: Incorporation of triterpenic derivatives within an o/w/o multiple emulsion: structure and release studies.
PubMed: Martius repair in urethrovaginal defects.
PubMed: Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica.
PubMed: Contact allergy to various ingredients of topical medicaments.
PubMed: Development of a novel dosage form for intramuscular injection of titrated extract of Centella asiatica in a mixed micellar system.
PubMed: [The modern approach to wound treatment].
PubMed: [Madecassol treatment of systemic and localized scleroderma].
PubMed: Quantitative determination of triterpenes in extracts and phytopreparations of Centella asiatica (L.) urban.
PubMed: Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer.
PubMed: Pharmacokinetics of the total triterpenic fraction of Centella asiatica after single and multiple administrations to healthy volunteers. A new assay for asiatic acid.
PubMed: Contact allergy to Centelase.
PubMed: Contact dermatitis due to Centelase.
PubMed: Clinical study of a new antikeloid agent.
PubMed: [Scleroderma in children].
PubMed: Triterpenoid saponin content and the expression level of some related genes in calli of Centella asiatica.
PubMed: The anti-thrombotic active constituents from Centella asiatica.
PubMed: Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.
PubMed: Advanced formulation and pharmacological activity of hydrogel of the titrated extract of C. asiatica.
PubMed: Hepatotoxicity associated with the ingestion of Centella asiatica.
PubMed: [Therapeutic uses for Asian yellow-flowered crowfoot, genus Ranunculus: the case of Blastoestimulina].
PubMed: Anti-herpes simplex virus activities of crude water extracts of Thai medicinal plants.
PubMed: Extraction and analysis of cosmetic active ingredients from an anti-cellulitis transdermal delivery system by high-performance liquid chromatography.
PubMed: Regioselective ring opening of steroidal epoxide with hydrides: formation of C(2)- and C(3)-deoxyasiatic acid derivatives.
PubMed: Corneal wound healing in the rabbit eye: activity of a fibronectin-splitting product.
PubMed: Oleanane and ursane glycosides from Schefflera octophylla.
PubMed: New multidrug regimen with indigenous drugs and dapsone in the treatment of lepromatous leprosy (preliminary report).
PubMed: [The clinical therapy of periodontal disease, the use of potassium hydroxide and the water-alcohol extract of Centella in combination with laser therapy in the treatment of severe periodontal disease].
PubMed: [Centella asiatica extract in venous disorders of the lower limbs. Comparative clinico-instrumental studies with a placebo].
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