EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

sodium glycerophosphate
disodium alpha-glycerophosphate

Supplier Sponsors

Name:disodium;2,3-dihydroxypropyl phosphate
CAS Number: 1555-56-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:216-304-3
Nikkaji Web:J8.671A
Molecular Weight:216.03729056
Formula:C3 H7 Na2 O6 P
NMR Predictor:Predict (works with chrome or firefox)
Category:antiplaque agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 485.50 °C. @ 760.00 mm Hg (est)
Flash Point: 477.00 °F. TCC ( 247.40 °C. ) (est)
logP (o/w): -2.839 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antiplaque agents
oral care agents
BOC Sciences
For experimental / research use only.
Sodium Glycerophosphate 95%
Global Calcium
Hydrated Sodium Glycerophosphate BP
Penta International
For experimental / research use only.
Disodium a-Glycerophosphate Hydrate >85.0%(T)
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: antiplaque agents
Recommendation for sodium glycerophosphate usage levels up to:
 not for fragrance use.
Recommendation for sodium glycerophosphate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):1555-56-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :14754
National Institute of Allergy and Infectious Diseases:Data
disodium;2,3-dihydroxypropyl phosphate
 disodium;2,3-dihydroxypropyl phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:1555-56-2
Pubchem (cid):14754
Pubchem (sid):134979642
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2919.90.5050
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
1-(dihydrogen phosphate)-1,2,3-propanetriol sodium salt
 disodium 2,3-dihydroxypropyl phosphate
 disodium 3-(phosphonatooxy)propane-1,2-diol
 disodium a-glycerophosphate
 disodium alpha-glycerophosphate
 disodium glycerophosphate
 disodium glyceryl phosphate
 disodium;2,3-dihydroxypropyl phosphate
 glycerol phosphate disodium salt
DL-a-glycerophosphate disodium salt hexahydrate
1,2,3-propanetriol, 1-(dihydrogen phosphate), sodium salt (1:2)
 sodium 3-phosphoroglycerate
 sodium a-glycerophosphate
 sodium DL-glycerophosphate


PubMed:Topical combined application of dexamethasone, vitamin C, and β-sodium glycerophosphate for healing the extraction socket in rabbits.
PubMed:Physical Compatibility of Calcium Chloride and Sodium Glycerophosphate in Pediatric Parenteral Nutrition Solutions.
PubMed:[Effect of CCL3 on osteoblast in myeloma bone disease].
PubMed:[Aluminum content in individual components, used to prepare adult total parenteral nutrition mixtures in Argentine, and in comparison with international regulation].
PubMed:The proliferation, differentiation, and mineralization effects of puerarin on osteoblasts in vitro.
PubMed:Physical Compatibility of Sodium Glycerophosphate and Calcium Gluconate in Pediatric Parenteral Nutrition Solutions.
PubMed:[Experimental study of repairing femoral bone defects with nHA/RHLC/PLA scaffold composite with endothelial cells and osteoblasts in canines].
PubMed:[Culture and induced multilineage differentiation of mesenchymal stem cells derived from human nasal mucosa].
PubMed:[The effect of osteogenic inducer on healing of tooth extraction sockets].
PubMed:Glycerophosphate is interchangeable with inorganic phosphate in terms of safety and serum pharmacokinetics.
PubMed:Glycerophosphate does not interact with components of parenteral nutrition.
PubMed:[Effects of drynaria total flavonoid on osteogenic differentiation of bone marrow mesenchymal stem cells at different glucose concentrations: experiment with rats].
PubMed:[Experimental study of directional differentiation of bone mesenchymal stem cells (BMSCs) to osteoblasts guided by serum containing cistanche deserticola].
PubMed:Directional differentiation of chicken spermatogonial stem cells in vitro.
PubMed:The support of matrix accumulation and the promotion of sheep articular cartilage defects repair in vivo by chitosan hydrogels.
PubMed:[Differentiation of human umbilical cord blood-derived mesenchymal stem cells into chondroblast and osteoblasts].
PubMed:[Effects of different phosphorus sources on the growth and toxin production of Prorocentrum lima].
PubMed:[An experimental study of the culture, isolation and biological characteristics of rat adipose tissue-derived stromal cells in vitro].
PubMed:[Heterotopic osteogenesis of autogenous marrow stromal cells on ceramic bovine bone/ hydrogel scaffold].
PubMed:Glycerophosphate as a phosphorus source in a defined medium for Pichia pastoris fermentation.
PubMed:[Induced differentiation of adult human bone marrow derived mesenchymal stem cells in vitro toward osteoblasts].
PubMed:[Biocompatibility of adult human osteoblasts with coral-derived hydroxyapatite in vitro].
PubMed:[Stability of Lactococcus lactis phages treated with sodium hypochlorite and during storage].
PubMed:Effects of various adjuvants (lactic acid, glycerol, and chitosan) on the injectability of a calcium phosphate cement.
PubMed:Sodium glycerophosphate in the treatment of neonatal hypophosphataemia.
PubMed:Bacterial regeneration of ammonium and phosphate as affected by the carbon:nitrogen:phosphorus ratio of organic substrates.
PubMed:[Immortalization of human dental pulp cells with transfecting of the plasmid, pMT1-neo].
PubMed:Comparison of diazo-coupling, formazan, and silver staining techniques for visualizing alkaline phosphatase isoenzymes after electrophoresis in homogeneous-pore and gradient-pore polyacrylamide gels.
PubMed:Stainer and Scholte's pertussis medium with an alternative buffer.
PubMed:Purification and Characterization of alpha-Amylase from Bacillus licheniformis CUMC305.
PubMed:Immunofluorescent staining experiments in parathyroid glands.
PubMed:[Histochemical study of the phosphomonoesterases of cells producing steroid hormones].
PubMed:Inhibition of human platelet aggregation by dimethylsulfoxide, dimethylacetamide, and sodium glycerophosphate.
PubMed:Ultrastructural characteristics of freeze-dried human blood platelets.
PubMed:Comparison of sodium -glycerophosphate and disodium phenyl phosphate as inhibitors of alkaline phosphatase in determination of 5'-nucleotidase activity of human serum.
PubMed:[High doses of sodium glycerophosphate in the therapy of gouty arthropathies].
PubMed:Microbiological assay for organic compounds in seawater. I. Quantitative assay procedures and biotin distribution.
PubMed:Studies in experimental diabetes. III. Effect of oestrogen therapy and its combination with intravenous glucose and intravenous sodium glycerophosphate in experimental (alloxan) diabetes in rats.
PubMed:[Combination of Betula Alba, sodium glycerophosphate and vitamin B1 (betul); therapeutic applications in dermatology].
PubMed:[Association of white birch, sodium glycerophosphate, and vitamin B1 in the treatment of sequels of hemiplegia, lumbar arthrosis, and neuritis; preliminary observations].
PubMed:[Myotrophic and myotonic effects of a new preparation, betul, a combination of sodium glycerophosphate, vitamin B1 and white birch].
PubMed:[Use of commercial sodium glycerophosphate in determination of phosphatase].
PubMed:[Adrenal cortex function in chronic rheumatism following intravenous administration of massive doses of sodium glycerophosphate].
PubMed:The sodium glycerophosphate factor in the technic for phosphatase activity.
PubMed:The Effects of Calcium Glycerophosphate, Sodium Glycerophosphate and Sodium Dihydrogen Phosphate upon the Skeleton of Rats kept on a Diet Deficient only in Fat-soluble Factor.
None found
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