peg/ppg-300/55 copolymer surfactant
oxirane, methyl, polymer with oxirane (300 mol EO, 55 mol PO average molar ratio)
 
Notes:
a copolymer of polyethylene and polypropylene ether glycol. it is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.
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2-methyloxirane; oxirane (300;55) (Click)
CAS Number: 9003-11-6Picture of molecule
Other: 106717-66-2
Formula: (C3 H6 O.C2 H4 O)x-
NMR Predictor: Predict (works with chrome or firefox)
Category: surfactant
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: surfactants
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50  175 mg/kg
Microvascular Research. Vol. 8, Pg. 320, 1974.

oral-mouse LD50  3000 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.

oral-mouse LD50  > 15000 mg/kg
Drug and Chemical Toxicology. Vol. 1, Pg. 89, 1977/1978.

oral-mouse LD50  45000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.

intraperitoneal-mouse LDLo  5000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.

intravenous-mouse LDLo  6000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.

oral-mouse LDLo  15000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.

oral-rabbit LD50  35000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.

oral-rat LD50  5700 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.

intraperitoneal-rat LDLo  10000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.

oral-rat LDLo  16000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LC50 320 mg/m3/4H
LIVER: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES
National Technical Information Service. Vol. OTS0539401

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Safety in Use Information:
Category: surfactant
Recommendation for peg/ppg-300/55 copolymer surfactant usage levels up to:
 not for fragrance use.
 
Recommendation for peg/ppg-300/55 copolymer surfactant flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Daily Med: search
NLM Hazardous Substances Data Bank: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 9003-11-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24751
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 2-methyloxirane; oxirane (300;55)
Chemidplus: 0009003116
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References:
 2-methyloxirane; oxirane (300;55)
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 9003-11-6
Pubchem (cid): 24751
Pubchem (sid): 134991398
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
KEGG (GenomeNet): D01941
HMDB (The Human Metabolome Database): Search
Haz-Map: View
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 methyl oxirane polymer with oxirane (300;55)
2-methyloxirane; oxirane (300;55)
 oxirane, methyl, polymer with oxirane (300 mol EO, 55 mol PO average molar ratio)
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