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piperazine dihydrochloride
dihydrochloride salt of diethylene diamine

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Name:piperazine dihydrochloride
CAS Number: 142-64-3Picture of molecule3D/inchi
Other(deleted CASRN):8049-00-1
ECHA EINECS - REACH Pre-Reg:205-551-2
FDA UNII: 17VU4Z4W88
MDL:MFCD00012754
Molecular Weight:159.05764000
Formula:C4 H12 Cl2 N2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nematocide
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (SATF):142-64-3 ; PIPERAZINE DIHYDROCHLORIDE
 
Physical Properties:
Appearance:whit to cream powder (est)
Food Chemicals Codex Listed: No
Melting Point: 318.00 to 320.00 °C. @ 760.00 mm Hg
Boiling Point: 149.30 °C. @ 760.00 mm Hg (est)
Vapor Pressure:4.050000 mmHg @ 25.00 °C. (est)
Flash Point: 121.00 °F. TCC ( 49.70 °C. ) (est)
logP (o/w): -1.171 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Sigma-Aldrich
For experimental / research use only.
Piperazine dihydrochloride hydrate purum, ≥97.0% (AT)
TCI AMERICA
For experimental / research use only.
Piperazine Dihydrochloride Monohydrate >98.0%(N)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 4900 mg/kg
Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 416, 1973.

intraperitoneal-mouse LD50 1970 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967.

Dermal Toxicity:
subcutaneous-mouse LD50 2030 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 4, Pg. 649, 1954.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nematocide
Recommendation for piperazine dihydrochloride usage levels up to:
 not for fragrance use.
 
Recommendation for piperazine dihydrochloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH Pocket Guide:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):142-64-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8893
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
piperazine dihydrochloride
Chemidplus:0000142643
EPA/NOAA CAMEO:hazardous materials
RTECS:142-64-3
 
References:
 piperazine dihydrochloride
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):8893
Pubchem (sid):134973402
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
FooDB:FDB020382
Export Tariff Code:2933.59.9500
ChemSpider:View
Formulations/Preparations:
•piperazine dihydrochloride 53% base is popular in dry feed or drinking water anthelmintic medication. •pipertab 2: composition: each tablet contains: piperazine dihydrochloride equivalent to 50 mg piperazine base. available in 500 tablet bottles. pipertab 10: composition: each tablet contains: piperazine dihydrochloride equivalent to 250 mg piperazine base. •52% piperazine base grades
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 diethylene diamine dihydrochloride
 dihydrochloride salt of diethylene diamine
 dowzene DHC
 piperazine, dihydrochloride
 piperazine, hydrochloride (1:2)
 
 
Notes:
Formerly used as a food additive; now no longer generally recognised as safe
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