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triflumizole
1-(1-((4-chloro-2-(trifluoromethyl)phenyl)imino)-2-propoxyethyl)-1H-imidazole

Supplier Sponsors

Name:	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine
CAS Number:	68694-11-1	3D/inchi
Other(deleted CASRN):	1135441-23-4
FDA UNII:	7J6Y4H9MV5
Nikkaji Web:	J26.588H
XlogP3-AA:	4.00 (est)
Molecular Weight:	345.75195960
Formula:	C15 H15 Cl F3 N3 O
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:herbicides / pesticides

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
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Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 1.25E+04 mg/L @ 25 °C (exp)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
herbicides / pesticides
Recommendation for triflumizole usage levels up to:
	not for fragrance use.

Recommendation for triflumizole flavor usage levels up to:
	not for flavor use.

Safety References:

European Food Safety Authority (EFSA) reference(s):

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Review of the existing maximum residue levels for triflumizole according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

EPI System: View

NIOSH International Chemical Safety Cards:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :91699

National Institute of Allergy and Infectious Diseases:Data

WISER:UN 2588

N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine

Chemidplus:0068694111

RTECS:68694-11-1

References:

	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	91699
Pubchem (cas):	68694-11-1

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
KEGG (GenomeNet):	C18493
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

1-(1-((4-	chloro-2-(trifluoromethyl)phenyl)imino)-2-propoxyethyl)-1H-imidazole
N-[4-	chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine
(E)-4-	chloro-alpha,alpha,alpha-trifluoro-N-(1-imidazol-1-yl)-2-propoxyethylidene-ortho-toluidine
1H-	imidazole, 1-((1E)-1-((4-chloro-2-(trifluoromethyl)phenyl)imino)-2-propoxyethyl)-
	trifumine

Articles:

PubMed:Management of Powdery Mildew in Squash by Plant and Alga Extract Biopesticides.

PubMed:Worker illness related to newly marketed pesticides--Douglas County, Washington, 2014.

PubMed:Simultaneous multi-determination and transfer of eight pesticide residues from green tea leaves to infusion using gas chromatography.

PubMed:Triazole-induced toxicity in developing rare minnow (Gobiocypris rarus) embryos.

PubMed:Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease.

PubMed:Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson׳s disease.

PubMed:Potential obesogen identified: fungicide triflumizole is associated with increased adipogenesis in mice.

PubMed:Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ).

PubMed:[Determination of 11 triazole fungicides in fruits using solid phase extraction and gas chromatography-tandem mass spectrometry].

PubMed:Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.

PubMed:Triflumizole.

PubMed:Multi-residue analysis of 30 currently used pesticides in fine airborne particulate matter (PM 2.5) by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry.

PubMed:Determination of triflumizole by differential pulse polarography in formulation, soil and natural water samples.

PubMed:Mutations in the CYP51 gene correlated with changes in sensitivity to sterol 14 alpha-demethylation inhibitors in field isolates of Mycosphaerella graminicola.

PubMed:Solubility enhancement of low soluble biologically active compounds--temperature and cosolvent dependent inclusion complexation.

PubMed:[Determination of triflumizole and its metabolite residues in vegetables by high performance liquid chromatography].

PubMed:[Multiresidue analysis of nitrogen-containing and sulfur-containing pesticides in agricultural products using dual-column GC-NPD/FPD].

PubMed:A novel ATP-binding cassette transporter involved in multidrug resistance in the phytopathogenic fungus Penicillium digitatum.

PubMed:Residue analysis of triflumizole and its metabolite in crops by high-performance liquid chromatography.

Notes:

None found

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