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CAS Number: 73049-73-7
Other(deleted CASRN):80702-37-0
FDA UNII: 0K9R94573C
Category:nutrient supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (SATF):73049-73-7 ; PEPTONES
FDA Regulation:
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1553 Peptones.
Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
American Laboratories
Anatone Powder 149
American Laboratories
Beef Peptone Powder 245
American Laboratories
Biological Concentrate 064
American Laboratories
Cooked Meat Medium 445
American Laboratories
Microbiotone Granular 148
American Laboratories
Microbiotone Powder 159
American Laboratories
Pharmatone Powder 061
American Laboratories
Pharmatone Powder 25B
American Laboratories
Platone 062
American Laboratories
Pork Peptone Powder 50A
American Laboratories
Proteose-Micro Granular 247
BOC Sciences
For experimental / research use only.
Peptone from casein and other animal proteins 95%
Tryptone USP – A1431 // A1401
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
nutrient supplements
Recommendation for peptones usage levels up to:
 not for fragrance use.
Recommendation for peptones flavor usage levels up to:
 not for flavor use.
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):73049-73-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Canada Domestic Sub. List:73049-73-7
Pubchem (sid):135348191
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 anatone powder 149
 beef peptone powder 245
 biological concentrate 064
 hyprotone powder 658
cooked meat medium 445
 microbiotone granular 148
 microbiotone powder 159
brewers peptone
 peptone powder 689
 pharmatone powder 061
 pharmatone powder 25B
 platone 062
 pork peptone powder 50A
 proteose-micro granular 247
 tryptone USP – A1431 // A1401


PubMed:Targeted peptides for the quantitative evaluation of casein plasminolysis in drinking milk.
PubMed:Statistical optimization of pigment production by Monascus sanguineus under stress condition.
PubMed:Analysis of bovine milk caseins on organic monolithic columns: an integrated capillary liquid chromatography-high resolution mass spectrometry approach for the study of time-dependent casein degradation.
PubMed:In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet.
PubMed:Is an organic nitrogen source needed for cellulase production by Trichoderma reesei Rut-C30?
PubMed:Effect of protein hydrolizates on growth kinetics and aminopeptidase activities of some Bifidobacterium species.
PubMed:Production and characterization of an extracellular polysaccharide from Streptomyces violaceus MM72.
PubMed:Improvement of Karmali agar by addition of polymyxin B for the detection of Campylobacter jejuni and C. coli in whole-chicken carcass rinse.
PubMed:Effect of soy and milk protein-related compounds on Listeria monocytogenes infection in human enterocyte Caco-2 cells and A/J mice.
PubMed:Endogenous metabolites as ligands for G protein-coupled receptors modulating risk factors for metabolic and cardiovascular disease.
PubMed:Potential of chicken by-products as sources of useful biological resources.
PubMed:A new strategy for improved glutathione production from Saccharomyces cerevisiae: use of cysteine- and glycine-rich chicken feather protein hydrolysate as a new cheap substrate.
PubMed:Influence of diluent and sample processing methods on the recovery of the biocontrol agent Pantoea agglomerans CPA-2 from different fruit surfaces.
PubMed:Aspergillus flavus grown in peptone as the carbon source exhibits spore density- and peptone concentration-dependent aflatoxin biosynthesis.
PubMed:Cholecystokinin enhances visceral pain-related affective memory via vagal afferent pathway in rats.
PubMed:[Characteristics of collagen's material bifidogenic properties].
PubMed:Optimization of cold-adapted lysozyme production from the psychrophilic yeast Debaryomyces hansenii using statistical experimental methods.
PubMed:Detection of Salmonella in meat: comparative and interlaboratory validation of a noncomplex and cost-effective pre-PCR protocol.
PubMed:Effect of zeolite (clinoptilolite) as feed additive in Tunisian broilers on the total flora, meat texture and the production of omega 3 polyunsaturated fatty acid.
PubMed:Thermal inactivation of infectious pancreatic necrosis virus in a peptone-salt medium mimicking the water-soluble phase of hydrolyzed fish by-products.
PubMed:Utilization of chicken feather hydrolysate as a novel fermentation substrate for production of exopolysaccharide and mycelial biomass from edible mushroom Morchella esculenta.
PubMed:[Factors responsible for transition of the carnivorous fungus Duddingtonia flagrans from saprophytic to zootrophic type of nutrition ].
PubMed:Modification of buffered peptone water for improved recovery of heat-injured Salmonella Typhimurium.
PubMed:Effects of nutritional and environmental conditions on Salmonella sp. biofilm formation.
PubMed:Detection of low numbers of healthy and sub-lethally injured Salmonella enterica in chocolate.
PubMed:Design and optimization of fermentation medium for enhanced bacteriocin production by probiotic bacterium Enterococcus faecium MC13.
PubMed:Optimization of nisin production by Lactococcus lactis UQ2 using supplemented whey as alternative culture medium.
PubMed:Antimicrobial effects of hypochlorite on Escherichia coli in water and selected vegetables.
PubMed:The detection and influence of food soils on microorganisms on stainless steel using scanning electron microscopy and epifluorescence microscopy.
PubMed:Relative gene expression in acid-adapted Escherichia coli O157:H7 during lactoperoxidase and lactic acid challenge in Tryptone Soy Broth.
PubMed:Characteristics and use of yellow stripe trevally hydrolysate as culture media.
PubMed:Microbial inactivation kinetics in soymilk during continuous flow high-pressure throttling.
PubMed:Supplementation of adjuvants for increasing the nutritive value and cell viability of probiotic fermented milk beverage.
PubMed:Application of yeast imprinting in biotechnology and process control.
PubMed:Cholecystokinin secretion induced by beta-conglycinin peptone depends on Galphaq-mediated pathways in enteroendocrine cells.
PubMed:Acetobacter fabarum sp. nov., an acetic acid bacterium from a Ghanaian cocoa bean heap fermentation.
PubMed:The detection of food soils and cells on stainless steel using industrial methods: UV illumination and ATP bioluminescence.
PubMed:Inactivation of bacterial pathogens in human milk by high-pressure processing.
PubMed:Peptones from diverse sources: pivotal determinants of bacterial growth dynamics.
PubMed:Proteiniborus ethanoligenes gen. nov., sp. nov., an anaerobic protein-utilizing bacterium.
PubMed:Cell surface hydrophobicity of Bacillus spp. as a function of nutrient supply and lipopeptides biosynthesis and its role in adhesion.
PubMed:Peptides derived from dolicholin, a phaseolin-like protein in country beans (Dolichos lablab), potently stimulate cholecystokinin secretion from enteroendocrine STC-1 cells.
PubMed:Role of nutrient limitation in the competition between Pseudomonas fluorescens and Escherichia coli O157: H7.
PubMed:Influence of peptone source on sporulation of Clostridium perfringens type A.
PubMed:Optimising the viability during storage of freeze-dried cell preparations of Campylobacter jejuni.
PubMed:Efficacy of supplemented buffered peptone water for the isolation of Campylobacter jejuni and C. coli from broiler retail products.
PubMed:Modeling growth, substrate consumption and product formation of Penicillium nalgiovense grown on meat simulation medium in submerged batch culture.
PubMed:Pork peptone stimulates cholecystokinin secretion from enteroendocrine cells and suppresses appetite in rats.
PubMed:Efficient production of poly-gamma-glutamic acid by Bacillus subtilis ZJU-7.
PubMed:Construction and analysis of fractional multifactorial designs to study attachment strength and transfer of Listeria monocytogenes from pure or mixed biofilms after contact with a solid model food.
PubMed:Ochratoxin A biosynthetic genes in Aspergillus ochraceus are differentially regulated by pH and nutritional stimuli.
PubMed:Growth of Lactobacillus plantarum in media containing hydrolysates of fish viscera.
PubMed:Use of hydrolysates from Atlantic cod (Gadus morhua L.) viscera as a complex nitrogen source for lactic acid bacteria.
PubMed:Fermentation conditions affecting the bacterial growth and exopolysaccharide production by Streptococcus thermophilus ST 111 in milk-based medium.
PubMed:Production of fructosyl transferase by Aspergillus oryzae CFR 202 in solid-state fermentation using agricultural by-products.
PubMed:Source of tryptone in growth medium affects oxidative stress resistance in Escherichia coli.
PubMed:Optimization of submerged culture requirements for the production of mycelial growth and exopolysaccharide by Cordyceps jiangxiensis JXPJ 0109.
PubMed:Abdominal vagal mediation of the satiety effects of CCK in rats.
PubMed:Growth of Lactobacillus paracasei ssp. paracasei on tofu whey.
PubMed:Effects of peripheral CCK receptor blockade on food intake in rats.
PubMed:Effect of rice--glycerol complex medium on the production of Lovastatin by Monascus ruber.
PubMed:Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats.
PubMed:Mn2+ alters peroxidase profiles and lignin degradation by the white-rot fungus Pleurotus ostreatus under different nutritional and growth conditions.
PubMed:Antibacterial activity of pepsin-digested lactoferrin on foodborne pathogens in buffered broth systems and ultra-high temperature milk with EDTA.
PubMed:Effects of UV irradiation on selected pathogens in peptone water and on stainless steel and chicken meat.
PubMed:Neuroendocrine control of intestinal mucosal mast cells under physiological conditions.
PubMed:Comparison of sample preparation methods for recovering Salmonella from raw fruits, vegetables, and herbs.
PubMed:Phosphate buffer increases recovery of Escherichia coli O157:H7 from frozen apple juice.
PubMed:Mild isolation procedure discloses new protein structural properties of beta-lactoglobulin.
PubMed:Pre-inoculation enrichment procedure enhances the performance of bacteriocinogenic Lactococcus lactis meat starter culture.
PubMed:Validation of thiosulfate for neutralization of acidified sodium chlorite in microbiological testing.
PubMed:Isolation of Alicyclobacillus acidoterrestris from fruit juices.
PubMed:Comparison of two commercial preparations of buffered peptone water for the recovery and growth of Salmonella bacteria from foods.
PubMed:Stressed salmonella are exposed to reactive oxygen species from two independent sources during recovery in conventional culture media.
PubMed:Lipase production by Penicillium restrictum using solid waste of industrial babassu oil production as substrate.
PubMed:Osmoprotection of Escherichia coli by peptone is mediated by the uptake and accumulation of free proline but not of proline-containing peptides.
PubMed:Role of cholecystokinin in the anorexia produced by duodenal delivery of peptone in rats.
PubMed:Gut vagal afferent lesions increase meal size but do not block gastric preload-induced feeding suppression.
PubMed:Ingredient supplementation effects on viability of probiotic bacteria in yogurt.
PubMed:A collaborative study on media for the enumeration of yeasts in foods.
PubMed:Production of a mixture of antimicrobial organic acids from lactose by co-culture of Bifidobacterium longum and Propionibacterium freudenreichii.
PubMed:Influence of growth temperature on inactivation and injury of Escherichia coli O157:H7 by heat, acid, and freezing.
PubMed:Aqueous two-phase systems: a novel approach for the separation of proteose peptones.
PubMed:Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene.
PubMed:Enhanced broth media for selective growth of Vibrio vulnificus.
PubMed:Interference of peptone and tyrosine with the lignin peroxidase assay.
PubMed:Optimisation of methodology for enumeration of xerophilic yeasts from foods.
PubMed:High-glutathione containing yeast Saccharomyces cerevisiae: optimization of production.
PubMed:Effects of ranitidine bismuth citrate on gastric acid secretion and gastrin release in subjects with and without Helicobacter pylori infection.
PubMed:Comparison of three selective media for detecting Fusarium species in foods: a collaborative study.
PubMed:Flocculation of the yeast Candida famata (Debaryomyces hansenii): an essential role for peptone.
PubMed:Improvement of Salmonella detection on motility enrichment media by ferrioxamine E-supplementation of pre-enrichment culture.
PubMed:Evaluation of diluents and media for enumerating Zygosaccharomyces rouxii in blueberry syrup.
PubMed:A substrate-mediated assay of bacterial proton efflux/influx to predict the degree of spoilage of beef mince stored at chill temperatures.
PubMed:Effect of substrate on the production of antifungal volatiles from Bacillus subtilis.
PubMed:Role of gastrin and cholecystokinin receptors in regulation of peptone-stimulated gastric acid secretion in conscious rats.
PubMed:Bacteriocin production by Carnobacterium piscicola LV 61.
PubMed:In vitro toxicity evaluation of a product obtained from carmoisine using Tetrahymena pyriformis cells.
PubMed:Asymptomatic H. pylori infection impairs pH inhibition of gastrin and acid secretion during second hour of peptone meal stimulation.
PubMed:Gastric branch vagotomy blocks nutrient and cholecystokinin-induced suppression of gastric emptying.
PubMed:15N- and 13C-labeled media from Anabaena sp. for universal isotopic labeling of bacteriocins: NMR resonance assignments of leucocin A from Leuconostoc gelidum and nisin A from Lactococcus lactis.
PubMed:The effect of H2-blockade on plasma gastrin concentration in patients with an achlorhydric stomach.
PubMed:Growth of Salmonella and competing flora in five commercial Rappaport-Vassiliadis (RV)-media.
PubMed:Elevation of meal-stimulated gastrin release in subjects with Helicobacter pylori infection: reversal by low intragastric pH.
PubMed:[Rappaport--Vassiliadis medium--a new liquid selectively-multiplying medium for detection of Salmonella in food].
PubMed:Stimulatory effect of pancreastatin on gastric acid secretion in conscious dogs.
PubMed:Action of neurotensin on meal-stimulated gastric acid secretion in the dog.
PubMed:Prolonged inhibition of meal-stimulated acid secretion and gastrin release following single subcutaneous administration of octreotide (SMS 201-995) in man.
PubMed:Disinfection with gaseous formaldehyde. Fifth Part: Influence of albumin, mucin and blood on the bactericidal and sporicidal effectiveness.
PubMed:Effect of mifentidine on peptone meal-stimulated gastric acid secretion and plasma gastrin levels in duodenal ulcer patients.
PubMed:Regulation of gastric acid secretion by neurotensin in man. Evidence against a hormonal role.
PubMed:Fat inhibits meal-stimulated gastric acid secretion after prostaglandin synthesis inhibition by indomethacin in man.
PubMed:Gastric acidification inhibits meal-stimulated gastric acid secretion after prostaglandin synthesis inhibition by indomethacin in humans.
PubMed:Fate of salmonellas and competing flora in meat sample enrichments in buffered peptone water and in Muller-Kauffmann's tetrathionate medium.
PubMed:The effect of an oral evening dose of nizatidine on nocturnal and peptone-stimulated gastric acid and gastrin secretion.
PubMed:Inhibition of food stimulated acid secretion by association of pirenzepine and ranitidine in duodenal ulcer patients.
PubMed:Evidence for reflex adrenergic inhibition of acid secretion in the conscious rat.
PubMed:Selective medium for isolation of Fusarium species and dematiaceous hyphomycetes from cereals.
PubMed:Encapsulation of proteins and peptides in milkfat: encapsulation efficiency and temperature and freezing stabilities.
PubMed:Gut hormone release induced by food ingestion.
PubMed:Cultivation of free-living stages of Trichostrongylus colubriformis in media without bacteria, animal tissue extract, or serum.
PubMed:Effect of pirenzepine and atropine on peptone meal-stimulated gastric secretion and plasma gastrin in healthy volunteers, patients with duodenal ulcer and vagotomized patients.
PubMed:Pathophysiologic mechanisms of allergic and pseudo-allergic reactions to foods, food additives and drugs.
PubMed:Glucose perfusion intragastric titration.
PubMed:[Secretion of pancreatic polypeptide in cats in response to different stimuli; correlation with gastric acid secretion].
PubMed:The effect of vasoactive intestinal polypeptide on meal-stimulated gastric acid secretion in man.
PubMed:Alkalotolerance of Yersinia enterocolitica as a basis for selective isolation from food enrichments.
PubMed:[(Studies on intragastric titration in man) ].
PubMed:Culture medium for selective isolation and enumeration of Gram-negative bacteria from ground meats.
PubMed:Complete inhibition of food-stimulated gastric acid secretion by combined application of pirenzepine and ranitidine.
PubMed:Comparison of KS and BLB media for enumeration of coliform organisms in milk.
PubMed:Gastric acid secretion is abnormally sensitive to endogenous gastrin released after peptone test meals in duodenal ulcer patients.
PubMed:Interactions of cimetidine and pirenzepine on peptone-stimulated gastric acid secretion in man.
PubMed:[Comparative tests of various liquid media for the preenrichment of salmonellae from milk powder (author's transl)].
PubMed:Methylguanidine content in food.
PubMed:Enrichment in Muller-Kauffmann's broth and Rappaport's broth from buffered peptone water in the isolation of salmonellae from minced meat.
PubMed:Enumeration of sublethally heated staphylococci in some dried foods.
PubMed:[Effect of the diluent on the aerobic bacterial count in raw minced meat and similar meats (author's transl)].
PubMed:Chemicals bathing the oxyntic gland area stimulate acid secretion in dog.
PubMed:Comparison of several methods for the isolation of salmonellae from egg products.
PubMed:Preliminary experiments with simulated silage.
PubMed:Carbon dioxide-protein interaction in a gas-solid phase.
PubMed:Gastric and pancreatic responses to meals varying in pH.
PubMed:Recovery of heated Clostridium perfringens type A spores on selective media.
PubMed:The role of vagal innervation in gastric and pancreatic responses to meals varying in pH.
PubMed:Serum gastrin and gastric acid responses to meals at various pH levels in man.
PubMed:Effect of processing milk upon association of added iron with different protein fractions.
PubMed:Evaluation and modifications of media for enumeration of Clostridium perfringens.
PubMed:On the role of food vacuole formation in the uptake of dissolved nutrients by Tetrahymena.
PubMed:Discrepancies in the enumeration of Escherichia coli.
PubMed:Fat synthesis from supplemented beet molasses by Penicillium soppi Zaleski in still and shaken cultures.
PubMed:Survival of Salmonella typhi in sea-water.
PubMed:Inactivation of Vibrio parahaemolyticus in distilled water.
PubMed:Submerged growth of the cultivated mushroom, Agaricus bisporus.
PubMed:The interaction of particulate material and dissolved foodstuffs in food uptake by Tetrahymena pyriformis.
PubMed:Effect of controlled atmosphere on growth of mold on synthetic media and fruit.
PubMed:Improved medium for enumeration of Clostridium perfringens.
PubMed:Effect of rehydration on recovery, repair, and growth of injured freeze-dried Salmonella anatum.
PubMed:Response of taxigenic and non-toxigenic strains of Aspergillus flavus to irradiation.
PubMed:Microbial degradation of organic matter in the deep sea.
PubMed:Respiratory responses to dissolved food of starved, normal and division-synchronized Tetrahymena cells.
PubMed:Rapid detection of sublethally impaired cells of Enterobacteriaceae in dried foods.
PubMed:Optimum skin blending method for quantifying poultry carcass bacteria.
PubMed:Diluent composition and the recovery of Escherichia coli.
PubMed:[Investigations on the suitability of different diluents and culture methods for cultural germ counts in pelletized feed samples].
PubMed:Detection and incidence of specific species of spoilage bacteria on fish. I. Methodology.
tsca definition 2008: the complex combination of various amino acids joined by peptide linkages obtained by the hydrolysis of animal tissue proteins.
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