EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

octafluorocyclobutane
cyclobutane, octafluoro-

Supplier Sponsors

Name:1,1,2,2,3,3,4,4-octafluorocyclobutane
CAS Number: 115-25-3Picture of molecule3D/inchi
Other(deleted CASRN):178459-70-6
ECHA EINECS - REACH Pre-Reg:204-075-2
FDA UNII: V9P1D0A21K
Nikkaji Web:J380H
Beilstein Number:1909266
MDL:MFCD00040334
XlogP3:1.60 (est)
Molecular Weight:200.03122560
Formula:C4 F8
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:propellants, aerating agents, and gas
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FDA Mainterm (SATF):115-25-3 ; OCTAFLUOROCYCLOBUTANE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.360 Octafluorocyclobutane.
 
Physical Properties:
Food Chemicals Codex Listed: No
Boiling Point: -5.99 °C. @ 760.00 mm Hg (est)
Vapor Pressure:2350.000000 mmHg @ 25.00 °C. (est)
Flash Point: -44.00 °F. TCC ( -41.90 °C. ) (est)
logP (o/w): 0.403 (est)
Soluble in:
 water, 23.6 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American Elements
Octafluorocyclobutane
TCI AMERICA
For experimental / research use only.
Octafluorocyclobutane >98.0%(GC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-mouse LCLo 78 pph/2H
Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 111, Pg. 39, 1975.
 
Safety in Use Information:
Category:
propellants, aerating agents, and gas
Recommendation for octafluorocyclobutane usage levels up to:
 not for fragrance use.
 
Recommendation for octafluorocyclobutane flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):115-25-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8263
National Institute of Allergy and Infectious Diseases:Data
1,1,2,2,3,3,4,4-octafluorocyclobutane
Chemidplus:0000115253
EPA/NOAA CAMEO:hazardous materials
 
References:
 1,1,2,2,3,3,4,4-octafluorocyclobutane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:115-25-3
Pubchem (cid):8263
Pubchem (sid):134974723
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB31292
FooDB:FDB003338
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 cyclobutane, octafluoro-
 cyclooctafluorobutane
perfluorocyclobutane
 freon C 318
 freon C-318
1,1,2,2,3,3,4,4-octafluorocyclobutane
 

Articles:

PubMed:Controlled droplet transport on a gradient adhesion surface.
PubMed:Rayleigh scattering measurements of several fluorocarbon gases.
PubMed:Control of interface nanoscale structure created by plasma-enhanced chemical vapor deposition.
PubMed:Nanotransfer printing using plasma etched silicon stamps and mediated by in situ deposited fluoropolymer.
PubMed:Visualization of inert gas wash-out during high-frequency oscillatory ventilation using fluorine-19 MRI.
PubMed:Stroke asymmetry of tilted superhydrophobic ion track textures.
PubMed:Structures of the hexafluorocyclopropane, octafluorocyclobutane, and decafluorocyclopentane radical anions probed by experimental and computational studies of anisotropic electron spin resonance (ESR) spectra.
PubMed:Design of experiment for optimization of plasma-polymerized octafluorocyclobutane coating on very high aspect ratio silicon molds.
PubMed:Computational and ESR studies of electron attachment to decafluorocyclopentane, octafluorocyclobutane, and hexafluorocyclopropane: electron affinities of the molecules and the structures of their stable negative ions as determined from 13C and 19F hyperfine coupling constants.
PubMed:Electron attachment and detachment and the electron affinity of cyclo-C4F8.
PubMed:Micromachined filter-chamber array with passive valves for biochemical assays on beads.
PubMed:Delayed suprachoroidal hemorrhage following filtration surgery. Case report.
PubMed:Longitudinal dispersion of gases measured in a model of the bronchial airways.
PubMed:Posterior lip traction caused by intravitreal gas.
PubMed:The insufflation of freon in vitreoretinal surgery.
PubMed:Hemodynamic effects of aerosol propellants. I. Cardiac depression in the dog.
PubMed:Octafluorocyclobutane in vitreous and aqueous humor replacement.
PubMed:Vitreous substitution with gases.
PubMed:Clinical trail of intravitreal C F in retinal detachment surgery.
PubMed:Toxicity of octafluorocyclobutane after intracameral injection.
PubMed:Octafluorocyclobutane and other gases for vitreous replacement.
PubMed:Toxicity studies with octafluorocyclobutane.
 
Notes:
Propellant and aerating agent in foamed or sprayed food products Octafluorocyclobutane is a dimer of tetrafluoroethylene. Its critical point is at 115.3 °C and 2.79 MPa.; Octafluorocyclobutane, or perfluorocyclobutane, C4F8, is a compound of carbon and fluorine used in the production and processing of semiconductor materials and devices, for example as a deposition gas and etchant. It has also been investigated as a refrigerant in specialised applications, as a replacement for Ozone depleting chlorofluorocarbon refrigerants.
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