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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 92.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 406.300000 mmHg @ 25.00 °C. (est) |
| Flash Point: | -38.00 °F. TCC ( -38.90 °C. ) (est)
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| logP (o/w): | -0.640 (est) |
| Soluble in: |
| | water, 9.39e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 2330 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 382, 1969.
intraperitoneal-rat LDLo 487 mg/kg
Toxicology Letters. Vol. 32, Pg. 73, 1986.
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| Dermal Toxicity: |
skin-rabbit LD50 1170 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 382, 1969.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for methoxyacetaldehyde usage levels up to: | | | not for fragrance use.
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| Recommendation for methoxyacetaldehyde flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetaldehyde, 2-methoxy- | | | acetaldehyde, methoxy- (8CI,9CI) | | 2- | methoxyacetaldehyde | | | methoxyethanal |
Articles:
| PubMed:Azithromycin-sulfonamide conjugates as inhibitors of resistant Streptococcus pyogenes strains. |
| PubMed:Efficient enzymatic synthesis of phosphoroselenoate RNA by using adenosine 5'-(alpha-P-seleno)triphosphate. |
| PubMed:Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein. |
| PubMed:Biotic and abiotic degradation behaviour of ethylene glycol monomethyl ether (EGME). |
| PubMed:Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine. |
| PubMed:Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides. |
| PubMed:Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether. |
| PubMed:High-throughput analysis of hemoglobin from neonates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. |
| PubMed:Immunochemical assay of hemoglobin with N(epsilon)-(carboxymethyl)lysine at lysine 66 of the beta chain. |
| PubMed:2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia. |
| PubMed:Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and Aldh2 gene targeting mouse. |
| PubMed:A novel compound heterozygote (FAP ATTR Arg104His/ATTR Val30Met) with high serum transthyretin (TTR) and retinol binding protein (RBP) levels. |
| PubMed:Concurrent teratogenic and mutagenic action of 2-methoxyethanol in Drosophila melanogaster larvae resulted in similar phenotypes: close resemblance to directed mutations. |
| PubMed:Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol. |
| PubMed:Oligosaccharides of recombinant mouse gelatinase B variants. |
| PubMed:The role of metabolism in 2-methoxyethanol-induced suppression of in vitro polyclonal antibody responses by rat and mouse lymphocytes. |
| PubMed:Interaction of human CYP17 (P-450(17alpha), 17alpha-hydroxylase-17,20-lyase) with cytochrome b5: importance of the orientation of the hydrophobic domain of cytochrome b5. |
| PubMed:Effects of reactive oxygen species (ROS) modulators, TEMPOL and catalase, on methoxyacetaldehyde (MALD) -induced chromosome aberrations in Chinese hamster ovary (CHO)-AS52 cells. |
| PubMed:Induction of deletion mutations by methoxyacetaldehyde in Chinese hamster ovary (CHO)-AS52 cells. |
| PubMed:Mutagenicity and cytotoxicity of 2-butoxyethanol and its metabolite, 2-butoxyacetaldehyde, in Chinese hamster ovary (CHO-AS52) cells. |
| PubMed:Mutagenicity of ethylene glycol ethers and of their metabolites in Salmonella typhimurium his-. |
| PubMed:Cytogenetic effects of 2-methoxyethanol and its metabolite, methoxyacetaldehyde, in mammalian cells in vitro. |
| PubMed:Evaluation of the clastogenic effects of 2-methoxyethanol in mice. |
| PubMed:Methoxyacetaldehyde, an intermediate metabolite of 2-methoxyethanol, is immunosuppressive in the rat. |
| PubMed:Fluorometric determination of L-tryptophan with methoxyacetaldehyde. |
| PubMed:Mutagenicity and cytotoxicity of 2-methoxyethanol and its metabolites in Chinese hamster cells (the CHO/HPRT and AS52/GPT assays). |
| PubMed:Antimicrobial effects of some mono- and bishydrazones. |
| PubMed:N-(cyanomethyl)- and N-(2-methoxy-1-cyanoethyl)anthracyclines and related carboxyl derivatives. |
| PubMed:Testicular toxicity of 2-methoxyacetaldehyde, a possible metabolite of ethylene glycol monomethyl ether, in the rat. |
| PubMed:Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat. |
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3D/inchi