EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

strontium chloride

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CAS Number: 10476-85-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:233-971-6
Molecular Weight:158.52400000
Formula:Cl2 Sr
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:oral care agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1.308e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: oral care agents
skin conditioning
soothing agents
Allan Chemical
Strontium Chloride
Barium & Chemicals
Strontium Chloride Technical Anhydrous Grade
Odor: characteristic
Use: Strontium salts, pyrotechnics, electron tubes, aquarium artificial sea water
BOC Sciences
For experimental / research use only.
Strontium chloride >98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Strontium Chloride anhydrous, powder, ≥99.99% trace metals basis
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LD50 5143 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(11), Pg. 18, 1965.

intraperitoneal-mouse LD50 908 mg/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.

intravenous-mouse LD50 148 mg/kg
Toxicology and Applied Pharmacology. Vol. 22, Pg. 150, 1972.

oral-mouse LD50 1874 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(11), Pg. 18, 1965.

oral-rabbit LD50 2735 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(11), Pg. 18, 1965.

intravenous-rabbit LDLo 1067 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 1898, 1981.

intraperitoneal-rat LD50 405 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

intravenous-rat LD50 222 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

oral-rat LD50 2250 mg/kg
Food Research. Vol. 7, Pg. 313, 1942.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
oral care agents
Recommendation for strontium chloride usage levels up to:
 not for fragrance use.
Recommendation for strontium chloride flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):10476-85-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :61520
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:WK8400000 for cas# 10476-85-4
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:10476-85-4
Pubchem (cid):61520
Pubchem (sid):135017895
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Potential Blenders and core components note
None Found
Potential Uses:
 oral care agents
Occurrence (nature, food, other):note
 not found in nature
 strontium chloride (SrCl2)
 strontium dichloride


PubMed:Radiopharmaceuticals for Palliation of Bone Pain in Patients with Castration-resistant Prostate Cancer Metastatic to Bone: A Systematic Review.
PubMed:[The role of systemic radiotherapy in the combined treatment for hormone-resistant prostate cancer].
PubMed:Effectiveness of a desensitizing agent for topical and home use for dentin hypersensitivity: a randomized clinical trial.
PubMed:Supression of sweating in palmar hyperhydrosis with 5% strontium chloride hexahydrate.
PubMed:Desensitizing efficacy of nano-carbonate apatite dentifrice and Er,Cr:YSGG laser: a randomized clinical trial.
PubMed:Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats.
PubMed:Excess cholesterol induces mouse egg activation and may cause female infertility.
PubMed:Role of cytoskeleton in regulating fusion of nucleoli: a study using the activated mouse oocyte model.
PubMed:Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures.
PubMed:Strontium chloride: can it be a new treatment option for ulcerative colitis?
PubMed:Ion-pair formation in aqueous strontium chloride and strontium hydroxide solutions under hydrothermal conditions by AC conductivity measurements.
PubMed:In vivo measurement of the absorption of strontium in the rumen and small intestine of sheep as an index of calcium absorption capacity.
PubMed:Three-day-old human unfertilized oocytes after in vitro fertilization/intracytoplasmic sperm injection can be activated by calcium ionophore a23187 or strontium chloride and develop to blastocysts.
PubMed:Factors affecting the rate of oxidation and resultant discolouration of tetracyclines contained in endodontic medicaments and irrigants.
PubMed:Successful pregnancy after SrCl2 oocyte activation in couples with repeated low fertilization rates following calcium ionophore treatment.
PubMed:[Application of chemical activation to in vitro fertilization by round spermatid injection in mice].
PubMed:Vibrations and reorientations of H2O molecules in [Sr(H2O)6]Cl2 studied by Raman light scattering, incoherent inelastic neutron scattering and proton magnetic resonance.
PubMed:Laser-induced breakdown spectroscopy (LIBS) analysis of calcium ions dissolved in water using filter paper substrates: an ideal internal standard for precision improvement.
PubMed:[Bone metastases treated with radiopharmaceuticals].
PubMed:Bone-seeking radiopharmaceuticals for treatment of osseous metastases, Part 1: α therapy with 223Ra-dichloride.
PubMed:(89)Sr bremsstrahlung single photon emission computed tomography using a gamma camera for bone metastases.
PubMed:[The non-hormonal treatment of metastatic prostate cancer].
PubMed:Calcium phosphate cements with strontium halides as radiopacifiers.
PubMed:Strontium-89 (Sr-89) chloride in the treatment of various cancer patients with multiple bone metastases.
PubMed:Vibrational and reorientational motions of H2O ligands, phase transition and thermal properties of [Sr(H2O)6]Cl2.
PubMed:Phosphorylated histone H2A.x in porcine embryos produced by IVF and somatic cell nuclear transfer.
PubMed:[A case of lung cancer pain relief and safe return home by strontium chloride].
PubMed:Effects of chemical combinations on the parthenogenetic activation of mouse oocytes.
PubMed:Surface adsorption in strontium chloride ammines.
PubMed:Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation.
PubMed:A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch.
PubMed:Downregulation of store-operated Ca2+ entry during mammalian meiosis is required for the egg-to-embryo transition.
PubMed:[Effects of strontium chloride activation on the cleavage rate and somatic cell nuclear transfer embryos in mice].
PubMed:Radionuclide therapy of painful bone metastases--a comparative study between consecutive radionuclide infusions, combination with chemotherapy, and radionuclide infusions alone: an in vivo comparison of their effectiveness.
PubMed:Live birth after SrCl(2) oocyte activation in previous repeated failed or low fertilization rates after ICSI of frozen-thawed testicular spermatozoa: case report.
PubMed:Expression of FGF4 mRNA is mediated by mating behaviours in mice.
PubMed:The combined treatment of calcium ionophore with strontium improves the quality of ovine SCNT embryo development.
PubMed:Clinical significance of zoledronic acid and strontium-89 in patients with asymptomatic bone metastases from non-small-cell lung cancer.
PubMed:Efficacy of a desensitizing toothpaste containing arginine and calcium carbonate on dentin surface pore structure and dentin morphology.
PubMed:Effect of desensitizing toothpastes on dentin.
PubMed:Radiosensitizing effects of arsenic trioxide on MCF-7 human breast cancer cells exposed to 89 strontium chloride.
PubMed:[Radionuclide therapy for the treatment of skeletal metastases of urological malignancies: a forgotten therapy?].
PubMed:Innovations for combating dentin hypersensitivity: current state of the art.
PubMed:[Possibilities of systemic radiotherapy with high-purity 89Sr chloride in the treatment of bone metastases].
PubMed:Use of radionuclides in metastatic prostate cancer: pain relief and beyond.
PubMed:[A case of thyroid medullary carcinoma with multiple painful bone metastases successfully treated with strontium-89 chloride].
PubMed:The effect of strontium and combinations of strontium and fluoride on the remineralization of artificial caries lesions in vitro.
PubMed:[Strontium chloride (89Sr-chloride) fractional injection method for bone metastases treatment].
PubMed:Secretome profile of mouse oocytes after activation using mass spectrum.
PubMed:Therapeutic strategies for bone metastases and their clinical sequelae in prostate cancer.
PubMed:Efficacy of a commercial dentifrice containing 2% strontium chloride and 5% potassium nitrate for dentin hypersensitivity: a 3-day clinical study in adults in China.
PubMed:The ionic atmosphere around A-RNA: Poisson-Boltzmann and molecular dynamics simulations.
PubMed:An in vitro study of the effect of aluminum and the combined effect of strontium, aluminum, and fluoride elements on early enamel carious lesions.
PubMed:[Initial report of strontium-89 chloride treatment for painful osseous metastases at Sakai Municipal Hospital].
PubMed:[Effects of 89SrCl2 treatment on CD4+ CD25+ regulatory T cells and its Foxp3 mRNA expression in cancer patients with bone metastases].
PubMed:Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride.
PubMed:The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-κB activation.
PubMed:[A trial of 89Sr bremsstrahlung SPECT].
PubMed:Ovine oocytes vitrified at germinal vesicle stage as cytoplast recipients for somatic cell nuclear transfer (SCNT).
PubMed:Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling.
PubMed:[Encounter of cancer cells with bone. Treatment of bone metastases from breast cancer].
PubMed:A new insight into the dissociating effect of strontium on bone resorption and formation.
PubMed:Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief.
PubMed:Strontium ions substitution in brushite crystals: the role of strontium chloride.
PubMed:Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation.
PubMed:Computational study of ion distributions at the air/liquid methanol interface.
PubMed:Biosurfactant production and growth kinetics of bacteria in a designer marine medium: improved physiochemical properties.
PubMed:[Underlying examination in the imaging of 89Sr bremsstrahlung radiation].
PubMed:Validation and efficacy of transgenerational mass marking of otoliths in viviparous fish larvae.
PubMed:High rates of bovine blastocyst development after ICSI-mediated gene transfer assisted by chemical activation.
PubMed:The Calcium-sensing Receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization.
PubMed:Anticryptococcal cytotoxicity of murine nonadherent cells is perforin and nonperforin mediated.
PubMed:Complete regression of multiple painful bone metastases from hepatocellular carcinoma after administration of strontium-89 chloride.
PubMed:Mild and efficient strontium chloride hexahydrate-catalyzed conversion of ketones and aldehydes into corresponding gem-dihydroperoxides by aqueous H2O2.
PubMed:Strontium and bone nanostructure in normal and ovariectomized rats investigated by scanning small-angle X-ray scattering.
PubMed:Preventive effect of commercial desensitizing toothpastes on bovine enamel erosion in vitro.
PubMed:Analysis of cat oocyte activation methods for the generation of feline disease models by nuclear transfer.
PubMed:Artificial neural network modeling and genetic algorithm based medium optimization for the improved production of marine biosurfactant.
PubMed:Evaluation of desensitizing agents on dentin permeability and dentinal tubule occlusion: an in vitro study.
PubMed:Crystallization and heavy-atom derivatization of StHsp14.0, a small heat-shock protein from Sulfolobus tokodaii.
PubMed:Setting time and expansion in different soaking media of experimental accelerated calcium-silicate cements and ProRoot MTA.
PubMed:Development of a novel method for quantitative evaluation of sensory skin irritation inhibitors.
PubMed:Synthesis and in vitro microbiological evaluation of novel 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidinones.
PubMed:Our experience on pain palliation of bone metastasis with Sr-89 or Sm-153 in cancer patients resistant to a conventional analgesic therapy. A retrospective study.
PubMed:Double activation improves rabbit freeze-thawed oocytes developmental potential.
PubMed:Evidenced-based review of clinical studies on endodontic diagnosis.
PubMed:Influence of fluoride concentration and ethanol pre-treatment on the reduction of the acid susceptibility of enamel.
PubMed:Influence of desensitizing agents on the microshear bond strength of adhesive systems to dentin.
PubMed:An experimental study of the effect of strontium pre-treatment on calcium release from carious and non-carious teeth.
PubMed:[Effect of double activation on the development of frozen-thawed oocytes after intracytoplasmic sperm injection].
PubMed:(170)Tm-EDTMP: a potential cost-effective alternative to (89)SrCl(2) for bone pain palliation.
PubMed:In vitro development of goat parthenogenetic and somatic cell nuclear transfer embryos derived from different activation protocols.
PubMed:The influence of different irradiation doses and desensitizer application on demineralization of human dentin.
PubMed:Bone marrow recovery following use of systemic (153)Sm-lexidronam and (89)Sr-chloride for bone pain palliation after myelosuppressive therapy.
PubMed:Cryptococcus neoformans directly stimulates perforin production and rearms NK cells for enhanced anticryptococcal microbicidal activity.
PubMed:Improvement in sensory pain rating after palliative systemic radionuclide therapy in patients with advanced prostate cancer.
PubMed:Radiation safety considerations for the bone seeking radiopharmaceuticals. 89SrCl2, 186Re-HEDP and 153Sm-EDTMP.
PubMed:[Studies on an analytic method for detection of prohibited ingredient, strontium dichloride in cosmetics].
PubMed:Clinical effectiveness of a strontium chloride- containing desensitizing agent over 6 months: a randomized, double-blind, placebo-controlled study.
PubMed:Effect of dentinal tubule occlusion by dentifrice containing nano-carbonate apatite.
PubMed:Detection of inorganic ions from water by electrospray ionization-ion mobility spectrometry.
PubMed:A combined treatment with ethanol and 6-dimethylaminopurine is effective for the activation and further embryonic development of oocytes from Sprague-Dawley and Wistar rats.
PubMed:Clinical evaluation of a dentifrice containing calcium sodium phosphosilicate (novamin) for the treatment of dentin hypersensitivity.
PubMed:A scanning electronic microscopy study of the action of different desensitizing agents on bovine dentin.
PubMed:Cytotoxicity of etidronic acid to human breast cancer cells.
PubMed:Birth and follow-up of babies born following ICSI using SrCl2 oocyte activation.
PubMed:Alterations in the protein kinase C signaling activated by a parthenogenetic agent in oocytes from reproductively old mice.
PubMed:Ecto-phosphatase activity on the external surface of Rhodnius prolixus salivary glands: modulation by carbohydrates and Trypanosoma rangeli.
PubMed:In vitro development of non-enucleated rat oocytes following microinjection of a cumulus nucleus and chemical activation.
PubMed:Influence of three different sealants on root dentin demineralization in situ.
PubMed:Birth of mice after intracytoplasmic injection of single purified sperm nuclei and detection of messenger RNAs and MicroRNAs in the sperm nuclei.
PubMed:Viability, acrosome morphology and fertilizing capacity of boar spermatozoa treated with strontium chloride.
PubMed:[Acid-base state of blood and accumulation of strontium in tissues of rats].
PubMed:Possible role of calcium on oocyte development after intracytoplasmic sperm injection in quail (Coturnix japonica).
PubMed:Calcium-induced quiescence of sperm motility in the bluegill (Lepomis macrochirus).
PubMed:Cumulus-specific genes are transcriptionally silent following somatic cell nuclear transfer in a mouse model.
PubMed:Bone seeking radiopharmaceuticals for palliation of pain in cancer patients with osseous metastases.
PubMed:A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases.
PubMed:Strontium oral load test in children with idiopathic hypercalciuria.
PubMed:The effect of three-dimensional demineralized bone matrix on in vitro cumulus-free oocyte maturation.
PubMed:Parthenogenetic development of in vitro matured porcine oocytes treated with chemical agents.
PubMed:Alkaline earth chloride hydrates: chlorine quadrupolar and chemical shift tensors by solid-state NMR spectroscopy and plane wave pseudopotential calculations.
PubMed:Chemical activation of parthenogenetic and nuclear transfer porcine oocytes using ionomycin and strontium chloride.
PubMed:Calcium supply, bone mineral density and genetically defined lactose maldigestion in a cohort of elderly men.
PubMed:Radiopharmaceutical therapy of bone metastases with 89SrCl2, 186Re-HEDP and 153Sm-EDTMP: a dosimetric study using Monte Carlo simulation.
PubMed:Anomalous small angle x-ray scattering determination of ion distribution around a polyelectrolyte biopolymer in salt solution.
PubMed:Successful pregnancy after ICSI with strontium oocyte activation in low rates of fertilization.
PubMed:Theoretical data of external Bremsstrahlung radiation cross-section of bone.
PubMed:[Effectiveness of repeated systematic radiotherapy for generalized prostate cancer].
PubMed:[Effect of emodin on NO-cGMP signal pathway in rat vascular endothelium in vitro].
PubMed:Radionuclide therapy with bone seeking radionuclides in palliation of painful bone metastases.
PubMed:Effect of Ca2+, Ba2+, and Sr2+ on alginate microbeads.
PubMed:Preclinical assessment of gastrooesophageal tolerance of the new antiosteoporotic drug strontium ranelate: an endoscopic study in monkeys.
PubMed:[Changes of immunologic parameters in patients with simple bone metastases treated with 89SrCl2].
PubMed:Dentin hypersensitivity: Part I.
PubMed:Serum concentrations of IL-2 and TNF-alpha in patients with painful bone metastases: correlation with responses to 89SrCl2 therapy.
PubMed:[A multicenter study to determine the efficacy and safety of strontium (89Sr) chloride for palliation of painful bony metastases in cancer patients].
PubMed:Systemic radionuclide therapy in pain palliation.
PubMed:Crystal structures and spectroscopic characterization of galactitol complexes of trivalent lanthanide and divalent alkaline earth chlorides.
PubMed:Strontium-induced rat egg activation.
PubMed:Parthenogenetic activation of mouse oocytes by strontium chloride: a search for the best conditions.
PubMed:Transplantation of male pronucleus derived from in vitro fertilization of enucleated oocyte into parthenogenetically activated oocyte results in live offspring in mouse.
PubMed:First hydrotalcite-like sulfonate coordination network incorporating robust cationic layers and flexible interlayer interactions.
PubMed:Effects of calcium, strontium, and barium on isolated phrenic nerve-diaphragm preparation of rat and their interactions with diltiazem and nifedipine.
PubMed:Palliation of bone pain in prostate cancer using chemotherapy and strontium-89. A randomized phase II study.
PubMed:Qualitative microanalysis of ions and ultrastructural changes in dentin exposed to laser irradiation and to metal salts solution.
PubMed:[Simultaneous determination of calcium and magnesium in urines by flame atomic absorption spectrometry].
PubMed:[Determination of 14 trace elements in soybean and its products by atomic absorption spectrometry].
PubMed:[Strontium-89 diagnosis and therapy of bone metastases].
PubMed:Studies of the electric-field-induced zero-field splitting for a substitution Mn2+ ion in SrCl2 crystal.
PubMed:Interaction between trehalose and alkaline-earth metal ions.
PubMed:Occlusion of dentin tubules by desensitizing agents.
PubMed:Use of mouse oocytes to evaluate the ability of human sperm to activate oocytes after failure of activation by intracytoplasmic sperm injection.
PubMed:Adsorption of divalent cations on DNA.
PubMed:[Effects of different treatments on oocytes activation and parthenogenesis in mouse].
PubMed:Next generation of targeted radiotherapy drugs emerging from the clinical pipeline.
PubMed:Metal-ion interactions with sugars. The crystal structure and FTIR study of an SrCl2-fructose complex.
PubMed:[Combined treatment for pain from bone metastases in patients with prostate cancer].
PubMed:[Evaluation of therapeutic effects of strontium-89 on osseous metastases of prostate cancer by bone scanning and B-AKP measurement].
PubMed:Effect of activation regimens for rat oocytes on full-term development after round spermatid injection.
PubMed:Activation and early parthenogenesis of bovine oocytes treated with ethanol and strontium.
PubMed:Development of a novel concept (Calcigard) for activation of calcium absorption capacity and prevention of milk fever.
PubMed:T cell receptor transfection shows non-HLA-restricted recognition of nickel by CD8+ human T cells to be mediated by alphabeta T cell receptors.
PubMed:A Phase I/II study of strontium-89 combined with gemcitabine in the treatment of patients with androgen independent prostate carcinoma and bone metastases.
PubMed:[Radiologic follow-up and prognosis of efficiency of systemic Sr-89 Cl-2 therapy of bone metastases in prostate cancer].
PubMed:Factors influencing chromosome condensation and development of cloned rat embryos.
PubMed:Dose-dependent effects of strontium on bone of chronic renal failure rats.
PubMed:Sugar interaction with metal ion: crystal structure and spectroscopic study of SrCl2.galactitol.4H2O.
PubMed:Targeting of osseous sites with alpha-emitting 223Ra: comparison with the beta-emitter 89Sr in mice.
PubMed:153Sm-EDTMP and (89)SrCl(2) in a dog with spontaneous osteosarcoma.
PubMed:Effects of low chronic doses of ionizing radiation on antioxidant enzymes and G6PDH activities in Stipa capillata (Poaceae).
PubMed:Strontium 89 in the treatment of pain due to diffuse osseous metastases: a university hospital experience.
PubMed:The activation of neuronal nitric-oxide synthase by various divalent cations.
PubMed:[Metabolic radiotherapy: what role will it have in 2001?].
PubMed:Kinetics of isotopic exchange between strontium polymolybdate and strontium ions in aqueous solution.
PubMed:A method for measurement of the uptake patterns of two beta-emitting radionuclides in the same tissue section with a digital silicon detector: application to a study of 89SrCl2 and 153Sm-EDTMP in a dog with spontaneous osteosarcoma.
PubMed:Strontium-89 (Metastron) and the bisphosphonate olpadronate reduce the incidence of spinal cord compression in patients with hormone-refractory prostate cancer metastatic to the skeleton.
PubMed:[Internal strontium-89 radiotherapy for malignant bony metastasis].
PubMed:Standardization of a 89Sr solution from a BIPM intercomparison using a liquid scintillation method.
PubMed:Effectiveness of desensitizing agents.
PubMed:Biochemical responses in cultured cells following exposure to (89)SrCl(2): potential relevance to the mechanism of action in pain palliation.
PubMed:Predictors of response to strontium-89 (Metastron) in skeletal metastases from prostate cancer: report of a single centre's 10-year experience.
PubMed:A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer.
PubMed:Evaluation of the use of Sr2+ in alginate immobilization of cells.
PubMed:Radionuclide therapy for painful bone metastases. An Italian multicentre observational study. Writing Committee of an Ad Hoc Study Group.
PubMed:Different cytoplasmic calcium contents among three species of Characeae.
PubMed:Contribution to the penetration of radionuclides across the skin. Concentration dependence of strontium through the skin in vitro.
PubMed:Therapy of metastatic bone pain.
PubMed:Incorporation and distribution of strontium in bone.
PubMed:Tryptophan fluorescence quenching by alkaline earth metal cations in deionized bacteriorhodopsin.
PubMed:Effects of brushing with a dentifrice for sensitive teeth on tubule occlusion and abrasion of dentin.
PubMed:Dantrolene inhibition of ryanodine receptor Ca2+ release channels. Molecular mechanism and isoform selectivity.
PubMed:Facts about sensitive teeth.
PubMed:The Collection of Indirect and Nonmedical Direct Costs (COIN) form: a new tool for collecting the invisible costs of androgen independent prostate carcinoma.
PubMed:The effects of cations on the activity of the gypsy moth (Lepidoptera: Lymantriidae) nuclear polyhedrosis virus.
PubMed:Comparison of fluorescence and rinsing methods for assessing dermal exposure.
PubMed:ESR dosimetry of 89Sr and 153Sm in bone.
PubMed:Less pain does equal better quality of life following strontium-89 therapy for metastatic prostate cancer.
PubMed:A mutation in alpha-tropomyosin(slow) affects muscle strength, maturation and hypertrophy in a mouse model for nemaline myopathy.
PubMed:Treatment of bone metastases of prostate cancer with strontium-89 chloride: efficacy in relation to the degree of bone involvement.
PubMed:[Treatment of metastatic bone pain with repeated doses of strontium-89 in patients with prostate neoplasm].
PubMed:Conformation of oligodeoxynucleotides associated with anionic liposomes.
PubMed:Strontium and samarium therapy for bone metastases from prostate carcinoma.
PubMed:Down-regulation of the inositol 1,4,5-trisphosphate receptor in mouse eggs following fertilization or parthenogenetic activation.
PubMed:Decreased serum E-selectin concentration after 89Sr-chloride therapy for metastatic prostate cancer bone pain.
PubMed:Modeling of internal dose distributions during SR-89 treatment of a patient with bone metastases.
PubMed:Citrate enhances olfactory receptor responses and triggers oscillatory receptor activity in the channel catfish.
PubMed:Radionuclides for metastatic bone pain palliation: a need for rational re-evaluation in the new millennium.
PubMed:Separation of chloride and sulfate ions in univalent and divalent cation forms from aqueous streams.
PubMed:The kinetics of oocyte activation and dynamics of polar body formation in Calomys musculinus and Calomys laucha (Rodentia-Sigmodontinae).
PubMed:Strontium as a marker for intestinal calcium absorption: the stimulatory effect of calcitriol.
PubMed:Biologic mechanisms of 89SrCl2 incorporation into type I collagen during bone mineralization.
PubMed:Strontium is a potent and selective inhibitor of sensory irritation.
PubMed:Metal-ion speciation in blood plasma incorporating the bisphosphonate, 1-hydroxy-4-aminopropilydenediphosphonate (APD), in therapeutic radiopharmaceuticals.
PubMed:Optical identification of calcium-dependent action potentials transiently expressed in the embryonic rat brainstem.
PubMed:Bone pain palliation with 85Sr therapy.
PubMed:Long-term effects of CO2 laser irradiation on treatment of hypersensitive dental necks: results of an in Vivo study.
PubMed:The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulum.
PubMed:Strontium-89 chloride in the treatment of bone metastases from breast cancer.
PubMed:[Effect of cadmium sulfate and strontium chloride on the glycogen content in hepatocytes of rats of various ages].
PubMed:[Cellular mechanisms of postnatal growth of rat liver in during chronic exposure of cadmium sulfate and strontium chloride].
PubMed:An investigation of the effect of a desensitizing dentifrice on dentinal tubules in vitro and in vivo.
PubMed:A process for the recovery of strontium from the urine of patients injected with 89Sr.
PubMed:Study of the diagnostic value of strontium, chloride, haemoglobin and diatoms in immersion cases.
PubMed:New research developments increase therapeutic options for thyroid cancer and bone pain palliation.
PubMed:Human and murine osteocalcin gene expression: conserved tissue restricted expression and divergent responses to 1,25-dihydroxyvitamin D3 in vivo.
PubMed:Strontium-89 for palliation of pain from bone metastases in patients with prostate and breast cancer.
PubMed:Quantitation of biochemical markers of bone resorption following strontium-89-chloride therapy for metastatic prostatic carcinoma.
PubMed:Minimal requirements for calcium oscillations driven by the IP3 receptor.
PubMed:Palliative therapy using rhenium-186-HEDP in painful breast osseous metastases.
PubMed:Systemic radionuclide therapy with strontium chloride Sr 89 for painful skeletal metastases in prostate and breast cancer.
PubMed:Parthenogenetic activation of Chinese hamster oocytes by chemical stimuli and its cytogenetic evaluation.
PubMed:Autopsy of a cadaver containing strontium-89-chloride.
PubMed:Treatment of metastatic carcinoma of the prostate.
PubMed:[The role of metastron in the treatment of prostate cancer].
PubMed:[Effectiveness of the radioactive strontium (89Sr) chloride agent, SMS.2P for pain palliation in patients with metastatic bone tumor in phase III multicenter clinical trial].
PubMed:The effects of fluorides and/or trace elements on the solubilities of enamel and cementum.
PubMed:[89Sr Therapy for pain relief in patients with bone metastases].
PubMed:Acceptance of minerals and other compounds by calcium-deprived rats: 24-h tests.
PubMed:Intestinal absorption of strontium chloride in healthy volunteers: pharmacokinetics and reproducibility.
PubMed:Strontium-89 chloride (Metastron) for palliative treatment of bony metastases. The University of Minnesota experience.
PubMed:Metastron (strontium-89 chloride) injections reimbursement issues.
PubMed:The advantage of CO2-treated dental necks, in comparison with a standard method: results of an in vivo study.
PubMed:Assessing the efficacy of three dentifrices in the treatment of dentinal hypersensitivity.
PubMed:Strontium chloride Sr 89 for treating pain from metastatic bone disease.
PubMed:An evaluation of four desensitizing agents for treatment of the post preparation tooth pain: silver nitrate, potassium nitrate, strontium chloride and ferric oxalate.
PubMed:Intestinal strontium absorption: from bioavailability to validation of a simple test representative for intestinal calcium absorption.
PubMed:Hypocalciuria in overt and subclinical celiac disease.
PubMed:Scanning electron microscopy and energy dispersive spectroscopy analysis of calciotraumatic lines in rat labial dentin after acute exposure to strontium chloride.
PubMed:Strontium 89 therapy for the palliation of pain due to osseous metastases.
PubMed:Sensitive method for analysis of strontium in human and animal plasma by graphite furnace atomic absorption spectrophotometry.
PubMed:Palliation of bone pain in patients with metastatic cancer using strontium-89 (Metastron).
PubMed:Dose measurement for 89Sr chloride injection.
PubMed:Effect of calcium ion on Hydrilla verticillata thylakoid membrane O2 evolution.
PubMed:Changes in the plasma electrolytes and metabolites of the rat following acute exposure to sodium fluoride and strontium chloride.
PubMed:[Phase II clinical trial of the radioactive strontium (89Sr) chloride agent, SMS. 2P for pain palliation in patients with prostate cancer with bone metastases].
PubMed:Poor reproducibility of strontium absorption test.
PubMed:Treating cancer pain.
PubMed:A retrospective analysis of the cost effectiveness of treatment with Metastron (89Sr-chloride) in patients with prostate cancer metastatic to bone.
PubMed:New therapeutic agents marketed in 1993.
PubMed:Biodistributions of radioactive bipositive metal ions in tumor-bearing animals.
PubMed:Phenotypic, molecular and genetic-characterization of transformed human bronchial epithelial-cell strains.
PubMed:Nurses' teaching guide aids in understanding new drug.
PubMed:A retrospective analysis of the cost effectiveness of treatment with Metastron in patients with prostate cancer metastatic to bone.
PubMed:Strontium-89 (Metastron) in the treatment of prostate cancer metastatic to bone.
PubMed:Radiopharmaceutical approved for relief of pain caused by bone metastases.
PubMed:Tooth sensitivity: mechanisms and management.
PubMed:Polymorphic regulation of membrane phospholipid composition in Escherichia coli.
PubMed:Direct flame atomic absorption spectrophotometric determination of Mn in rocks, nodules, soils and related materials using tartaric acidKClSrCl(2) mixture.
PubMed:[Treatment of symptomatic bone metastases of prostatic carcinoma using strontium chloride (Sr-89)].
PubMed:Dental hypersensitivity: recent advances in diagnosis and treatment.
PubMed:The structure of dentine after the injection of strontium chloride by backscattered electron imaging in the scanning electron microscope.
PubMed:Mechanistic studies of the plasma membrane block to polyspermy in mouse eggs.
PubMed:Some biochemical aspects of the protective effect of strontium chloride on gamma-irradiated rats.
PubMed:Effects of hyaluronate, strontium and prolonged incubation on different sperm parameters.
PubMed:The effect of strontium chloride hexahydrate dentifrices on plaque accumulation and gingival inflammation.
PubMed:[The efficacy of therapy using 89Sr-strontium chloride in 200 patients with bone metastases of a prostatic cancer].
PubMed:Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity.
PubMed:Effect of NaCl on catalysis of lipid oxidation by the soluble fraction of fish muscle.
PubMed:Dentifrice abrasivity and cervical dentinal hypersensitivity. Results 12 weeks following cessation of 8 weeks' supervised use.
PubMed:Developmental potential and chromosome constitution of strontium-induced mouse parthenogenones.
PubMed:Strontium-89 chloride for pain palliation in prostatic skeletal malignancy.
PubMed:Dentine hypersensitivity: a review.
PubMed:Topical varnish containing strontium in a sustained-release device as treatment for dentin hypersensitivity.
PubMed:[The treatment of dentin hypersensitivity].
PubMed:[Dentin hypersensitivity: etiology and methods of treatment].
PubMed:Effect of plaque of five toothpastes used in the treatment of dentin hypersensitivity.
PubMed:[Effects of strontium on incisor and femurs in rats under drinking condition at constant concentrations of fluoride].
PubMed:Clinical management of dentin hypersensitivity using cathode and anode iontophoresis.
PubMed:Over-the-counter dentifrices in the treatment of tooth hypersensitivity. Review of clinical studies.
PubMed:Historic review of the management of tooth hypersensitivity.
PubMed:Clastogenic activity of strontium chloride on bone marrow cells in vivo.
PubMed:Effects of various metals on hepatic bile calcium excretion in rats: the stimulatory effect of zinc is mediated through acetylcholine action.
PubMed:[Dentinal hypersensitivity. Comparative study of amine fluoride paste and strontium chloride paste].
PubMed:Strontium and bromide as tracers in X-ray microanalysis of biological tissue.
PubMed:The distribution and retention of 89Sr in mice after a single intravenous injection of high and low doses.
PubMed:[Dental hypersensitivity: its treatment].
PubMed:Influence of strontium chloride on blood platelet function.
PubMed:Comparative study of effectiveness of strontium chloride and formalin containing dentifrices in relieving dental hypersensitivity.
PubMed:Sr2+ activates cross-bridge phosphorylation and latch state in smooth muscle.
PubMed:Effects of calcium preloading on the growth of calcium carbonate crystals in the endolymphatic sac of the tree frog, Hyla arborea japonica.
PubMed:Effects of ethylene glycol-bis-(beta-aminoethyl ether)-N,N'-tetraacetic acid on rabbit sinoatrial node cells treated with cardiotonic steroids.
PubMed:[Dentinal hypersensitivity in periodontal disease. Aetiology Aetiology--management].
PubMed:Effects of ionic and non-ionic solutions on intradental nerve activity in the cat.
PubMed:Effect of strontium chloride on bone resorption induced by prostaglandin E2 in cultured bone.
PubMed:A comparative study of disturbed mineralization of rat incisor enamel induced by strontium and fluoride administration.
PubMed:Fertilization of human oocytes by microinjection of a single spermatozoon under the zona pellucida.
PubMed:Single inhalation exposure to 90SrCl2 in the beagle dog: late biological effects.
PubMed:Efficacy of strontium chloride in dental hypersensitivity.
PubMed:Incorporation of strontium into the calcium carbonate crystals of the endolymphatic sac in the tree frog (Hyla arborea japonica).
PubMed:Single inhalation exposure to 90SrCl2 in the beagle dog: hematological effects.
PubMed:A comparative study of two clinical techniques for treatment of root surface hypersensitivity.
PubMed:Clinical evaluation of the effectiveness of aminfluoride fluid, aminfluoride gelée, and strontiumchloride paste in relieving dentine sensitivity.
PubMed:[Strontium chloride in the treatment of dental hypersensitivity].
PubMed:Growth aspects of calcium carbonate crystals of the endolymphatic sac in the tree frog (Hyla arborea japonica): a pulse-chase study.
PubMed:Histochemistry of adenylate cyclase activity in the anterior segment of the eye: a methodological evaluation with biochemical background.
PubMed:Hematologic depression following therapy with strontium-89 chloride.
PubMed:NK-leukocyte chemotactic factor (NK-LCF): a large granular lymphocyte (LGL) granule-associated chemotactic factor.
PubMed:[Clinical evaluation of ZAROSEN as a desensitizing cavity varnish (1). Use in inlay restorations].
PubMed:Eicosanoid synthesis by rabbit hydronephrotic cortical interstitial cells in culture.
PubMed:Short-term effects of fluoride and strontium on bone formation and resorption in the mouse.
PubMed:Desensitizing agents. A review.
PubMed:Calcium enhances the hemolytic action of bile salts.
PubMed:Characteristics of 45Ca uptake by the rabbit lens.
PubMed:Clinical evaluation of strontium chloride as a modified addition to the periodontal pack, in treatment of root hypersensitivity following periodontal surgery.
PubMed:Strontium-89 therapy for the pain of osseous metastases.
PubMed:The effectiveness of a fluoride varnish and a desensitizing toothpaste in treating dentinal hypersensitivity.
PubMed:Strontium-85 in the fetuses of pregnant rats and mice.
PubMed:Effect of low doses of stable strontium on bone metabolism in rats.
PubMed:Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity.
PubMed:Efficacy of desensitizing agents in dentifrices for hypersensitive teeth.
PubMed:[Intestinal absorption of calcium in chronic pancreatitis].
PubMed:[Comparative studies on 99mTc-pyrophosphate and 85Sr-chloride for skeletal imaging].
PubMed:Cytochemical studies of adenylate cyclase in the choroid plexus and brain vessels of rat and mouse.
PubMed:Reducing dentinal hypersensitivity with strontium chloride and potassium nitrate.
PubMed:Comparison of diluents for serum magnesium estimation by atomic absorption spectrophotometry.
PubMed:A comparison of the effects of strontium chloride and calcium chloride on alveolar bone.
PubMed:Cytochemical demonstration of adenylate cyclase with strontium chloride in the rat pancreas.
PubMed:A comparisoin of the R25 modification of Rappaport s enrichment medium with strontium chloride B for salmonella isolation from sewage polluted natural water.
PubMed:Home treatment for dentinal hypersensitivity: a comparative study.
PubMed:The effectiveness of an electro-ionizing toothbrush in the control of dentinal hypersensitivity.
PubMed:Current treatment for dentinal hypersensitivity. At-home treatment.
PubMed:The cytochemical demonstration of NaK dependent adenosine triphosphatase at electrocyte level in Eigenmannia virescens (Gymnotidae).
PubMed:Delineation of aspergilloma and granuloma with radiogallium and radiostrontium.
PubMed:[Basic principles for the control of tooth sensitivity].
PubMed:Ultramicroscopy of hypomineralized responses in rat incisor dentine to injected strontium.
PubMed:Effects of strontium chloride (SrCl2) on 3H-thymidine uptake into rat lymphocytes.
PubMed:Controlled clinical evaluation of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery.
PubMed:[The effect of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery (author's transl)].
PubMed:The effect of strontium chloride upon alveolar bone.
PubMed:Mineral metabolism of the healing arterial wall.
PubMed:[Dentifrice with strontium chloride. Efficiency related to time of application].
PubMed:The effect of fluoride and strontium application on dentin: in vivo and in vitro studies.
PubMed:Air-lock system for the transfer of reactive samples to the Philips EM 300S electron microscope.
PubMed:[Microscopic picture of dental periapical tissues in teeth with root canals filled with paste containing zinc oxide eugenol or the same paste with addition of strontium chloride].
PubMed:A new desensitizing dentifrice: preliminary report.
PubMed:Short-term toxicity of strontium chloride in rats.
PubMed:[Biophsical study of dental tissues under the effect of a local strontium application].
PubMed:An evaluation of selective broths based on the bi-selenite ion and on hypertonic strontium chloride in Salmonellae detection in egg products.
PubMed:A comparison of strontium chloride M broth, and mannitol, selenite, cystine broth in the isolation of salmonellae from egg products.
PubMed:Hemodynamic effects of strontium chloride in acute experimental myocardial infarction.
PubMed:Enrichment procedures for the isolation of Salmonella, Arizona, Edwardsiella and Shigella from faeces.
PubMed:The hemodynamic effects of strontium chloride in the intact dog.
PubMed:An evaluation of strontium chloride, Rappaport and strontium selenite enrichment for the isolation of salmonellas from man, animals, meat products and abattoir effluents.
PubMed:[Comparison of the effect of tetracyclines, sodium fluoride and strontium chloride on the content of citric acid in the rat incisor].
PubMed:Strontium chloride B and E.E. enrichment broth media for the isolation of Edwardsiella, Salmonella and Arizona species from tiger snakes.
PubMed:Strontium chloride toothpaste--effectiveness as related to duration of use.
PubMed:[Studies on the dental enamel after the use of strontium chloride as odontotropic agent].
PubMed:Controlled clinical comparison between a strontium chloride and a sodium monofluorophosphate toothpaste in diminishing root hypersensitivity.
PubMed:Strontium chloride and strontium selenite enrichment broth media in the isolation of Salmonella.
PubMed:The pathologic basis of the strontium bone scan. Studies following administration of strontium chloride Sr 85 and strontium nitrate Sr 85.
PubMed:Percutaneous absorption of radioactive strontium chloride Sr 89 (89SrCl2). A comparison with 11 other metal compounds.
PubMed:[Strontium chloride dentifrice to control dental hypersensitivity].
PubMed:[On the effect of choline chloride and strontium chloride on 45Ca-effluence in the guinea pig atrium].
PubMed:An investigation into the reputed desensitizing effect of applying silver nitrate and strontium chloride to human dentine.
PubMed:[Evaluation of the use of strontium chloride in the treatment of tooth sensitivity following periodontal therapy].
PubMed:The effect of strontium chloride on peripheral nerve in comparison to the action of "stabilizer" and "labilizer" compounds.
PubMed:[Dentifrices with strontium chloride].
PubMed:Preliminary study of the effects of a strontium chloride dentifrice for the control of hypersensitive teeth.
PubMed:A comparison of the absorption and retention by rabbits of strontium-90 incorporated into plant material and of added strontium chloride in the diet.
PubMed:[Pharmacology of strontium chloride].
PubMed:[Strontium chloride analgesia of the dentin in dental erosion, atypical defects and dental caries].
PubMed:[Preventive effect of fluorinated toothpaste and strontium chloride].
PubMed:[Diagnosis of paradentosis in children and possibility of its prevention with the aid of strontium chloride].
PubMed:Effect of strontium chloride feeding on the rat molars and their supporting tissue.
PubMed:[Use of strontium chloride as a means of permanent anesthesia in enamel and dentin hyperesthesia].
PubMed:The Production of Acidosis by Ingestion of Magnesium Chloride and Strontium Chloride.
metastron is the tradename of strontium-89 which is used for the relief of bone pain in cancer patients with skeletal metastases.
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