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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 85.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 439.20 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 427.00 °F. TCC ( 219.40 °C. ) (est)
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| logP (o/w): | 2.130 |
| Soluble in: |
| | water, 430 mg/L @ 20 °C (exp) | | | water, 250.4 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1000 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C54, 1991.
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| Dermal Toxicity: |
skin-rat LD50 > 6810 mg/kg
Pesticide Manual. Vol. 9, Pg. 560, 1991.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for metazachlor usage levels up to: | | | not for fragrance use.
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| Recommendation for metazachlor flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the review of the existing maximum residue levels (MRLs) for metazachlor according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
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Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
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Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for metazachlor in light of confirmatory data
View page or View pdf
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Peer review of the pesticide risk assessment for the active substance metazachlor in light of confirmatory data submitted
View page or View pdf
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Modification of the existing maximum residue level for metazachlor in Chinese cabbage
View page or View pdf
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Evaluation of confirmatory data following the Article 12 MRL review and modification of the existing maximum residue levels for metazachlor in various commodities
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :49384 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide |
| Chemidplus:0067129082 |
| RTECS:AB5442000 for cas# 67129-08-2 |
References:
| | 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 49384 |
| Pubchem (sid): | 135009166 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)- | | 2- | chloro-N-(2,6-dimethyl phenyl)-N-(1H-pyrazol-1-yl methyl)acetamide | | 2- | chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-acetamide | | 2- | chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide | | 2- | chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide | | 2- | chloro-N-(pyrazol-1-ylmethyl)acet-2',6'-xylidide | | N-(2,6- | dimethylphenyl)-2-chloro-N-(pyrazolylmethyl)acetamide | | | metazachlor [BSI] [ISO] | | N-((1H- | pyrazol-1-yl)methyl)-2-chloro-N-(2,6-dimethylphenyl)acetamide |
Articles:
| PubMed:Investigating the dynamics of two herbicides at a karst spring in Germany: Consequences for sustainable raw water management. |
| PubMed:Sorption of polar herbicides and herbicide metabolites by biochar-amended soil. |
| PubMed:Influence of formulation on mobility of metazachlor in soil. |
| PubMed:Dynamics and mitigation of six pesticides in a "Wet" forest buffer zone. |
| PubMed:Accumulation and half-lives of 13 pesticides in muscle tissue of freshwater fishes through food exposure. |
| PubMed:Risk assessment of herbicides and booster biocides along estuarine continuums in the Bay of Vilaine area (Brittany, France). |
| PubMed:Pesticide pressure and fish farming in barrage pond in Northeastern France. Part II: residues of 13 pesticides in water, sediments, edible fish and their relationships. |
| PubMed:Low molecular weight poly(lactic acid) microparticles for controlled release of the herbicide metazachlor: preparation, morphology, and release kinetics. |
| PubMed:Pesticide pressure and fish farming in barrage pond in northeastern France. Part III: how management can affect pesticide profiles in edible fish? |
| PubMed:Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. |
| PubMed:Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography-time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry. |
| PubMed:Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle. |
| PubMed:Development of an enzyme-linked immunosorbent assay for determination of pretilachlor in water and soil. |
| PubMed:Selected pesticides adsorption and desorption in substrates from artificial wetland and forest buffer. |
| PubMed:Multiresidue method to quantify pesticides in fish muscle by QuEChERS-based extraction and LC-MS/MS. |
| PubMed:Herbicide effects of metazachlor on duckweed (Lemna minor and Spirodela polyrhiza) in test systems with different trophic status and complexity. |
| PubMed:Specific interactions of chloroacetanilide herbicides with human ABC transporter proteins. |
| PubMed:Measurement and modelling of glyphosate fate compared with that of herbicides replaced as a result of the introduction of glyphosate-resistant oilseed rape. |
| PubMed:Response of plankton communities in freshwater pond and stream mesocosms to the herbicide metazachlor. |
| PubMed:Effects of the herbicide metazachlor on macrophytes and ecosystem function in freshwater pond and stream mesocosms. |
| PubMed:Comparison of different sorbents for multiresidue solid-phase extraction of 16 pesticides from groundwater coupled with high-performance liquid chromatography. |
| PubMed:Environmental fate of herbicides trifluralin, metazachlor, metamitron and sulcotrione compared with that of glyphosate, a substitute broad spectrum herbicide for different glyphosate-resistant crops. |
| PubMed:Glyphosate adsorption in soils compared to herbicides replaced with the introduction of glyphosate resistant crops. |
| PubMed:Wet deposition of pesticides and nitrophenols at two sites in Denmark: measurements and contributions from regional sources. |
| PubMed:The very-long-chain fatty acid synthase is inhibited by chloroacetamides. |
| PubMed:Pesticide pollution remains severe after cleanup of a stockpile of obsolete pesticides at Vikuge, Tanzania. |
| PubMed:Pesticide residues on the external surfaces of field crop sprayers: occupational exposure. |
| PubMed:Pesticide residues on the external surfaces of field-crop sprayers: environmental impact. |
| PubMed:Effects of pesticides on yeasts isolated from agricultural soil. |
| PubMed:Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. |
| PubMed:Predictability of combined effects of eight chloroacetanilide herbicides on algal reproduction. |
| PubMed:Effects of transgenic glufosinate-tolerant oilseed rape (Brassica napus) and the associated herbicide application on eubacterial and Pseudomonas communities in the rhizosphere. |
| PubMed:Determination of polar pesticides with atmospheric pressure chemical ionisation mass spectrometry-mass spectrometry using methanol and/or acetonitrile for solid-phase desorption and gradient liquid chromatography. |
| PubMed:An immunoassay for metolachlor detection in river water and soil. |
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3D/inchi