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sodium ferrocyanide
tetrasodium hexacyanoferrate

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CAS Number: 13601-19-9Picture of molecule3D/inchi
Other(deleted CASRN):1330-26-3
ECHA EINECS - REACH Pre-Reg:237-081-9
Molecular Weight:303.91207712
Formula:C6 Fe N6 Na4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:anticaking agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Additive: Ferrocyanides of Calcium, Potassium and Sodium
GSFA Codex: Sodium ferrocyanide (535)
DG SANTE Food Additives:sodium ferrocyanide
Physical Properties:
Appearance:yellow crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 25.70 °C. @ 760.00 mm Hg (est)
Vapor Pressure:740.000000 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -0.250 (est)
Soluble in:
Insoluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Charkit Chemical
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
anticaking agents
Recommendation for sodium ferrocyanide usage levels up to:
 not for fragrance use.
Recommendation for sodium ferrocyanide flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Re-evaluation of sodium ferrocyanide (E 535), potassium ferrocyanide (E 536) and calcium ferrocyanide (E 538) as food additives
View page or View pdf

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):13601-19-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :26129
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
tetrasodium iron(2+) hexacyanide
EPA/NOAA CAMEO:hazardous materials
 tetrasodium iron(2+) hexacyanide
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:13601-19-9
Pubchem (cid):26129
Pubchem (sid):134989773
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
grades: technical, cp
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 sodium prussiate yellow
 tetrasodium ferrocyanide
 tetrasodium hexacyanoferrate
 tetrasodium iron(2+) hexacyanide


PubMed:Exogenous NO depletes Cd-induced toxicity by eliminating oxidative damage, re-establishing ATPase activity, and maintaining stress-related hormone equilibrium in white clover plants.
PubMed:Acute self-induced poisoning with sodium ferrocyanide and methanol treated with plasmapheresis and continuous renal replacement therapy successfully: a case report.
PubMed:Nitric oxide contributes to minerals absorption, proton pumps and hormone equilibrium under cadmium excess in Trifolium repens L. plants.
PubMed:[Effects of exogenous nitric oxide on the growth and nitrogen metabolism of alfalfa seedlings under salt stress].
PubMed:Acute effects of road salts and associated cyanide compounds on the early life stages of the unionid mussel Villosa iris.
PubMed:[Effects of exogenous nitric oxide on active oxygen metabolism and photosynthetic characteristics of tomato seedlings under cadmium stress].
PubMed:Nitric oxide supplementation alleviates ammonium toxicity in the submerged macrophyte Hydrilla verticillata (L.f.) Royle.
PubMed:Sodium nitroprusside-mediated alleviation of iron deficiency and modulation of antioxidant responses in maize plants.
PubMed:Selective gray matter staining of human brain slices: optimized use of cadaver materials.
PubMed:Exogenous nitric oxide protect cucumber roots against oxidative stress induced by salt stress.
PubMed:Involvement of nitric oxide in light-mediated greening of barley seedlings.
PubMed:Comparative study of flux of FITC-labeled Dextran 4000 on normal (iso)- and hyper-osmolarity in basal side in caco-2 cell monolayers.
PubMed:Evidence that nitroprusside stimulates glucose uptake in isolated rat cardiomyocytes via mitogen-activated protein kinase.
PubMed:Characterisation of castor oil by on-line and off-line non-aqueous reverse-phase high-performance liquid chromatography-mass spectrometry (APCI and UV/MALDI).
PubMed:Effects of a fire-retardant chemical to fathead minnows in experimental streams.
PubMed:The effects of ultraviolet-B radiation on the toxicity of fire-fighting chemicals.
PubMed:Study of acute pharmacologic effects of prolactin on calcium and water transport in the rat colon by an in vivo perfusion technique.
PubMed:Acute effects of prolactin on passive calcium absorption in the small intestine by in vivo perfusion technique.
PubMed:A morphometric, electron microscopic analysis of tissue channels shown by ionic tracer in normal and tensioned rat molar apical periodontal ligament.
PubMed:Reflection coefficients and water permeability in rat proximal tubule.
PubMed:Glomerular filtration rate in conscious unrestrained starlings under dehydration.
PubMed:ADH-dependent nephron heterogeneity in rats with hereditary hypothalamic diabetes insipidus.
PubMed:Further studies on the blood-brain barrier to low molecular weight substances. An ultrastructural cytochemical study.
PubMed:Morphologic demonstration of tubular obstruction in acute renal failure.
PubMed:Compensatory renal hypertrophy in dogs: single nephron glomerular filtration rate.
PubMed:[Biliary clearance and intrahepatic distribution of sucrose and sodium ferrocyanide in cholestasis due to ethinyl estradiol].
PubMed:Morphologic evidence to support the role of tubular leakage as a cause of anuria induced by meercury poisoning.
PubMed:Use of sodium ferrocyanide as glomerular indicator to study the functional heterogeneity of nephrons.
PubMed:Short-term feeding study of sodium ferrocyanide in rats.
PubMed:[Evaluation of the glomerular filtration rate using the sodium ferrocyanide method in experimental acute renal insufficiency].
PubMed:Effect of sodium ferrocyanide and bicarbonate on reabsorption of inorganic sulfate in renal tubules.
PubMed:Early post mortem renal changes studied in mice with one kidney exteriorized. 1. The reliability of the experimental method as evaluated by the diuretic response to mannitol and sodium ferrocyanide.
PubMed:Measurement of "extracellular fluid space" in infants by equilibration technic using inulin and sodium ferrocyanide.
PubMed:A method for the determination of sodium ferrocyanide at low concentrations in body fluids.
None found
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