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2,2-bis(para-(2,3-epoxypropoxy)phenyl) propane
2,2-bis(4-hydroxyphenyl)propane bis(2,3-epoxypropyl) ether

Supplier Sponsors

Name:2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane
CAS Number: 1675-54-3Picture of molecule3D/inchi
Other(deleted CASRN):1018476-17-9
ECHA EINECS - REACH Pre-Reg:216-823-5
FDA UNII: F3XRM1NX4H
Nikkaji Web:J14.164J
Beilstein Number:299026
MDL:MFCD00080480
XlogP3-AA:4.00 (est)
Molecular Weight:340.41908000
Formula:C21 H24 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Contact Materials:2,2-bis(4-hydroxyphenyl)propane bis(2,3-epoxypropyl) ether
 
Physical Properties:
Appearance:yellowish brown liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 3.685 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
2,2-Bis(4-hydroxyphenyl)propane Diglycidyl Ether 95%
Santa Cruz Biotechnology
For experimental / research use only.
BADGE ≥85%
Sigma-Aldrich: Sigma
For experimental / research use only.
Bisphenol A diglycidyl ether
TCI AMERICA
For experimental / research use only.
2,2-bis(para-(2,3-Epoxypropoxy)phenyl)propane >85.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 4000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2219, 1981.

oral-mouse LD50 15600 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2219, 1981.

oral-rabbit LD50 1980 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2219, 1981.

intraperitoneal-rat LD50 2200 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2219, 1981.

oral-rat LD50 11300 uL/kg
Union Carbide Data Sheet. Vol. 4/21/1967

Dermal Toxicity:
skin-rabbit LD50 20000 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2219, 1981.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
indirect food additives: adhesives and components of coatings
Recommendation for 2,2-bis(para-(2,3-epoxypropoxy)phenyl) propane usage levels up to:
 not for fragrance use.
 
Recommendation for 2,2-bis(para-(2,3-epoxypropoxy)phenyl) propane flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to 2,2-bis(4-hydroxyphenyl)propane bis(2,3-epoxypropyl)ether (Bisphenol A diglycidyl ether, BADGE). REF. No 13510 and 39700.
View page or View pdf

EPI System: View
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):1675-54-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2286
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane
Chemidplus:0001675543
EPA/NOAA CAMEO:hazardous materials
RTECS:1675-54-3
 
References:
 2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:1675-54-3
Pubchem (cid):2286
Pubchem (sid):134981197
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C14348
HMDB (The Human Metabolome Database):HMDB32737
FooDB:FDB010699
Export Tariff Code:2910.90.2000
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 diglycidyl ether of bisphenol A
 epoxide A
2,2-bis(4-hydroxyphenyl)propane bis(2,3-epoxypropyl) ether
2,2'-((1-methyl ethylidene) bis(4,1-phenylene oxymethylene)) bisoxirane
2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane
bisphenol A diglycidyl ether
4,4'-isopropylidene diphenol epichlorohydride
 
 
Notes:
Potential food contaminant arising from its use in epoxy resin coatings for cans, concrete vats and tanks, etc.
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