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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white waxy solid (est) |
| Assay: | 99.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 60.00 to 61.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 247.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 10.000000 mmHg @ 100.00 °C. |
| Flash Point: | 198.00 °F. TCC ( 92.22 °C. )
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| logP (o/w): | 6.325 (est) |
| Soluble in: |
| | water, 0.1075 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
subcutaneous-mouse LD50 > 10000 mg/kg
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20(5/6), Pg. 772, 1973.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for cyclododecane usage levels up to: | | | not for fragrance use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| PubMed:Secondary Organic Aerosol Composition from C12 Alkanes. |
| PubMed:Self-assembly triggered by self-assembly: Optically active, paramagnetic micelles encapsulated in protein cage nanoparticles. |
| PubMed:In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4. |
| PubMed:Methodology for labeling proteins and peptides with lead-212 (212Pb). |
| PubMed:Paternally inherited ABCC8 mutation causing diffuse congenital hyperinsulinism. |
| PubMed:Sensitization of tumor to ²¹²Pb radioimmunotherapy by gemcitabine involves initial abrogation of G2 arrest and blocked DNA damage repair by interference with Rad51. |
| PubMed:The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. |
| PubMed:Eryngiolide A, a cytotoxic macrocyclic diterpenoid with an unusual cyclododecane core skeleton produced by the edible mushroom Pleurotus eryngii. |
| PubMed:Sublimable C5A delivery provides sustained and prolonged anti-HIV microbicidal activities. |
| PubMed:Molecular recognition of hydrocarbon guests by a supramolecular capsule formed by the 4:4 self-assembly of tris(Zn(2+)-cyclen) and trithiocyanurate in aqueous solution. |
| PubMed:(212)Pb-radioimmunotherapy induces G(2) cell-cycle arrest and delays DNA damage repair in tumor xenografts in a model for disseminated intraperitoneal disease. |
| PubMed:Cyclododecane exposure in the field of conservation and restoration of art objects. |
| PubMed:Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes. |
| PubMed:Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles. |
| PubMed:Complexation of syndiotactic polystyrene with 12-crown-4. |
| PubMed:Facile synthesis of 1-(acetic acid)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododecane: a reactive precursor chelating agent. |
| PubMed:A new bifunctional Gd(III) complex of enhanced efficacy for MR-molecular imaging applications. |
| PubMed:Radiosynthesis of new [90Y]-DOTA-based maleimide reagents suitable for the prelabeling of thiol-bearing L-oligonucleotides and peptides. |
| PubMed:Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents. |
| PubMed:Stratigraphic analysis of organic materials in wall painting samples using micro-FTIR attenuated total reflectance and a novel sample preparation technique. |
| PubMed:PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes. |
| PubMed:Radiohybridization PET imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-peptide nucleic acid-peptide nanoparticles. |
| PubMed:One-pot synthesis of lactams from cycloalkanes and tert-butyl nitrite by using N-hydroxyphthalimide as key catalyst. |
| PubMed:Transition-metal (Ti,V,Cr,Mn,Fe,Co,Cu) containing ordered nanoporous materials: novel heterogeneous catalysts for selective oxidation reactions. |
| PubMed:An apparent critical point in binary mixtures: experimental and simulation study. |
| PubMed:On the development of sensor molecules that display Fe(III)-amplified fluorescence. |
| PubMed:Mass, EPR, IR and electronic spectroscopic studies on newly synthesized macrocyclic ligand and its transition metal complexes. |
| PubMed:Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia. |
| PubMed:A comparison of the fish bioconcentration factors for brominated flame retardants with their nonbrominated analogues. |
| PubMed:Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins. |
| PubMed:Formation of two diverse classes of poly(amino-alkoxide) chelates and their mononuclear and polynuclear lanthanide(III) complexes. |
| PubMed:Synthesis and DNA binding properties of a cationic 2,2':6',2"-terpyridine cobalt(II) complex containing an oligopeptide. |
| PubMed:Synthesis and notable antimalarial activity of acyclic peroxides, L-(alkyldioxy)-L-(methyldioxy)cyclododecanes. |
| PubMed:Metal ion-dependent molecular inclusion chemistry: inclusion of aromatic anions by coordinated 1,4,7,10-tetrakis((S)-2-hydroxy-3-phenoxypropyl)-1,4,7,10-tetraazacyclododecane. |
| PubMed:Conformational Study of trans-Cyclododecene by Dynamic NMR Spectroscopy and Computational Methods. |
| PubMed:Intercalation of multiple carbon atoms between the carbonyls of alpha-diketones. |
| PubMed:Oligonucleotide conjugates of Eu(III) tetraazamacrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage. |
| PubMed:Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes 203Pb and 212Pb. |
| PubMed:Is absolute noninvasive temperature measurement by the Pr[MOE-DO3A] complex feasible. |
| PubMed:Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA). |
| PubMed:Fast spectroscopic imaging for non-invasive thermometry using the Pr[MOE-DO3A] complex. |
| PubMed:Degradation of alicyclic molecules by Rhodococcus ruber CD4. |
| PubMed:Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides. |
| PubMed:Conformational analysis of six- and twelve-membered ring compounds by molecular dynamics. |
| PubMed:Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by (1)H-NMR Spectroscopy. |
| PubMed:Phase I study of intravenous Lu-labeled CC49 murine monoclonal antibody in patients with advanced adenocarcinoma. |
| PubMed:Effects of cyclic 12-, 8-, and 6-carbon compounds on glutathione S-transferase activity. |
| PubMed:Ferric enterobactin transport system in Escherichia coli K-12. Extraction, assay, and specificity of the outer membrane receptor. |
| PubMed:Structural effects on Arthrobacter methylene hydroxylase activity. |
| PubMed:Some derivatives of cyclododecane. |
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3D/inchi