Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Soluble in: |
| water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 4 mg/kg KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED British Journal of Pharmacology and Chemotherapy. Vol. 25, Pg. 223, 1965.
unreported-mouse LD50 15 mg/kg British Journal of Cancer. Vol. 6, Pg. 160, 1952.
intraperitoneal-rat LD50 3500 ug/kg KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED British Journal of Pharmacology and Chemotherapy. Vol. 21, Pg. 581, 1963.
oral-rat LD50 15 mg/kg KIDNEY, URETER, AND BLADDER: OTHER CHANGES
BEHAVIORAL: GENERAL ANESTHETIC
GASTROINTESTINAL: OTHER CHANGES Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
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Dermal Toxicity: |
skin-guinea pig LD50 14 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948.
subcutaneous-rabbit LDLo 50 mg/kg Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 10, Pg. 25, 1968.
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Inhalation Toxicity: |
inhalation-guinea pig LCLo 25 ppm/8H KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 2, 1948.
inhalation-mouse LC50 400 mg/m3/2H BEHAVIORAL: MUSCLE WEAKNESS
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 41, 1966.
inhalation-rabbit LCLo 100 mg/m3/2H BLOOD: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 41, 1966.
inhalation-rat LC50 100 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.
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Safety in Use Information:
Category: | indirect food additives: adhesives and components of coatings |
Recommendation for aziridine usage levels up to: | | not for fragrance use.
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Recommendation for aziridine flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| aziran | aza | cyclopropane | | dihydro-1H-azirine | | dimethylenimine | | ethylene imine | | ethyleneimine |
Articles:
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