malathion
butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester

Supplier Sponsors

CAS Number: 121-75-5 3D/inchi Other(deleted CASRN): 11096-67-6 ECHA EINECS - REACH Pre-Reg: 204-497-7 FDA UNII: U5N7SU872W Nikkaji Web: J381F Beilstein Number: 1804525 MDL: MFCD00036233 XlogP3-AA: 2.40 (est) Molecular Weight: 330.36039200 Formula: C10 H19 O6 P S2 NMR Predictor: Predict (works with chrome, Edge or firefox) Category:herbicides / pesticides   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: yellow to dark-brown liquid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 2.80 °C. @ 760.00 mm Hg logP (o/w): 2.360 Soluble in:   water, 143 mg/L @ 20 °C (exp)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Sigma-Aldrich For experimental / research use only. Malathion PESTANAL®, analytical standard   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-bird - wild LD50 400 mg/kg Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. intraarterial-cat LDLo 1820 ug/kg "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964. oral-cattle LD50 53 mg/kg PERIPHERAL NERVE AND SENSATION: FASCICULATIONS BEHAVIORAL: REGIDITY BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Indian Veterinary Journal. Vol. 56, Pg. 650, 1979. unreported-cattle LD50 53 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: EXCITEMENT Indian Journal of Animal Sciences. Vol. 49, Pg. 314, 1979. oral-chicken LD50 600 mg/kg BEHAVIORAL: FOOD INTAKE (ANIMAL) Indian Journal of Experimental Biology. Vol. 9, Pg. 455, 1971. intraperitoneal-dog LD50 1857 mg/kg Toxicology and Applied Pharmacology. Vol. 15, Pg. 244, 1969. oral-duck LD50 1485 ug/kg Down to Earth. Vol. 35, Pg. 25, 1979. intraperitoneal-guinea pig LD50 271 mg/kg Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 236, Pg. 202, 1959. oral-guinea pig LD50 570 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 626, 1955. intraperitoneal-hamster LD50 2400 mg/kg Archives of Toxicology. Vol. 58, Pg. 152, 1986. unreported-mammal (species unspecified) LD50 500 mg/kg "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 357, 1971. oral-man LDLo 471 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Archiv fuer Toxikologie. Vol. 23, Pg. 11, 1967. intravenous-man TDLo 14 uL/kg VASCULAR: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Japanese Journal of Acute Medicine. Vol. 16, Pg. 367, 1992. intraperitoneal-mouse LD50 193 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 129, Pg. 699, 1968. intravenous-mouse LD50 184 mg/kg Bratislavske Lekarske Listy. Vol. 38, Pg. 151, 1958. oral-mouse LD50 190 mg/kg "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 56, 1982. unreported-mouse LD50 375 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985. oral-rabbit LDLo 1200 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION U.S. Army, Environmental Hygiene Agency Reports. Vol. 99-002-74/1976 intraperitoneal-rat LD50 250 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1926, 1972. intravenous-rat LD50 50 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 626, 1955. oral-rat LD50 290 mg/kg "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 56, 1982. unreported-rat LD50 450 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985. Dermal Toxicity: skin-guinea pig LD50 6700 mg/kg Toxicological Information on Cyanamid Insecticides. Vol. 8/1966 subcutaneous-guinea pig LD50 450 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 122, 1965. skin-mouse LD50 2330 mg/kg Agricultural and Biological Chemistry. Vol. 27, Pg. 684, 1963. subcutaneous-mouse LD50 221 mg/kg Osaka Igaku Zasshi. Vol. 71, Pg. 6099, 1959. skin-rabbit LD50 4100 mg/kg "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 142, 1976. subcutaneous-rabbit LD50 280 mg/kg SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 122, 1965. skin-rat LD50 > 4444 mg/kg Proceedings of the Annual Meeting of the New Jersey Mosquito Extermination Association. Vol. -, Pg. 155, 1957. subcutaneous-rat LD50 400 mg/kg SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 122, 1965. Inhalation Toxicity: inhalation-cat LCLo 10 mg/m3/4H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 56, 1982. inhalation-rat LC50 43790 ug/m3/4H Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 56(2), Pg. 80, 1991.   Safety in Use Information: Category: herbicides / pesticides Recommendation for malathion usage levels up to:   not for fragrance use.   Recommendation for malathion flavor usage levels up to:   not for flavor use.   Safety References: European Food Safety Authority (EFSA) reference(s): Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level View page or View pdf Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for malathion in light of confirmatory data View page or View pdf EPI System: View ClinicalTrials.gov:search Daily Med:search NIOSH International Chemical Safety Cards:search NIOSH Pocket Guide:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search Carcinogenic Potency Database:Search EPA GENetic TOXicology:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :4004 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate Chemidplus:0000121755 EPA/NOAA CAMEO:hazardous materials RTECS:121-75-5   References:   diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 121-75-5 Pubchem (cid): 4004 Pubchem (sid): 134973192   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View UM BBD: Search KEGG (GenomeNet): C07497 HMDB (The Human Metabolome Database): Search ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms: S-(1,2-bis( aethoxy-carbonyl)-aethyl)-O,O-dimethyl-dithiophosphat   american cyanamid 4,049   butanedioic acid, ((dimethoxyphosphinothioyl)-thio)-, diethyl ester, (+-)-   butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester   camathion   carbethoxy malathion S-(1,2-bis( carbethoxy)ethyl) O,O-dimethyl dithiophosphate   carbetovur   carbetox   carbofos   carbophos   chemathion   cimexan   compound 4049   cythion   detmol MA S-(1,2- di(ethoxycarbonyl)ethyl) dimethyl phosphorothiolothionate S-(1,2- dicarbethoxyethyl) O,O-dimethyldithiophosphate   dicarboethoxyethyl O,O-dimethyl phosphorodithioate   diethyl ((dimethoxyphosphinothioyl)thio)butanedioate   diethyl (+-)-mercaptosuccinate, S-ester with O,O-dimethyl phosphorodithioate   diethyl (dimethoxyphosphinothioylthio)succinate   diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate   diethyl mercaptosuccinate S-ester with O,O-dimethylphosphorodithioate   diethyl mercaptosuccinate, O,O-dimethyl dithiophosphate, S-ester   diethyl(dimethoxythiophosphorylthio)succinate (( dimethoxyphosphinothioyl)thio)butanedioic acid diethyl ester O,O- dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl) dithiophosphate O,O- dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate O,O- dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate O,O- dimethyl S-1,2-di(ethoxycarbamyl)ethyl phosphorodithioate O,O- dimethyl-S-1,2-(dicarbaethoxyaethyl)-dithiophosphat O,O- dimethyl-S-1,2-dikarbetoxylethylditiofosfat O,O- dimethyldithiophosphate diethylmercaptosuccinate   dithiophosphate de O,O-dimethyle et de S-(1,2-dicarboethoxyethyle)   dithiophosphate de O,O-dimethyle et de S-(1,2-dicarboethoxyethyle) [French]   dorthion   emmatos extra   ethiolacar S-(1,2-bis( ethoxy-carbonyl)-ethyl)-O,O-dimethyl-dithiofosfaat   forthion   fosfothion   fosfotion   fosfotion 550   fyfanon   hilthion   insecticide no. 4049   karbofos   kill-a-mite   kop-thion   kypfos   latka 4049   malacide   malafor   malagran   malakill   malamar   malamar 50   malaphos   malaspray   malathiazol   malathion E50   malathyl   malatol   malatox   maldison   malphos   mercaptosuccinic acid diethyl ester   mercaptothion   mercaptotion   moscarda   oleophosphothion   phosphorodithioic acid, O,O-dimethyl ester, S-ester with diethyl mercaptosuccinate   phosphothion   sadofos   sadophos   succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethyl phosphorodithioate   succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethylphosphorodithioate   sumitox   TAK   taskil   Articles:   None found yet. Try the PubMed Search.

Notes: a wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.

Please share your Comments.
Email Address:
Top of Page Home