EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

peg-8 stearate
poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (8 mol EO average molar ratio)

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CAS Number: 9004-99-3Picture of molecule3D/inchi
FDA UNII:0324G66D0E
Nikkaji Web:J110.879D
XlogP3-AA:7.80 (est)
Molecular Weight:636.90796000
Formula:C34 H68 O10
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI:Search
JECFA Food Additive: Polyoxyethylene (8) Stearate
GSFA Codex: Polyoxyethylene (8) stearate (430)
 
Physical Properties:
Appearance:cream waxy paste (est)
Food Chemicals Codex Listed: No
Boiling Point: 438.40 °C. @ 760.00 mm Hg (est)
Flash Point: 328.00 °F. TCC ( 164.60 °C. ) (est)
logP (o/w): 7.629 (est)
Soluble in:
 alcohol
 methanol
 acetone
 ether
 ethyl acetate
 
Organoleptic Properties:
Odor Description:at 100.00 %. mild fatty
Taste Description: bitter fatty
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: emulsifying agents
humectants
surfactants
 
Suppliers:
BOC Sciences
For experimental / research use only.
Polyoxyethylene (8) stearate 95%
Croda
Cithrol™ 4MS
Odor: bland
Use: O/W emulsifier. High molecular weight members are also used as viscosity builders in detergent systems. Can be used for melting point control. Electrolyte tolerant and suitable for use in antiperspirants.
Croda
Myrj™ S8
Odor: bland
Use: High HLB co-emulsifier for O/W systems and conditioning agent.
Lipo Chemicals
Lipopeg® 4-S
Odor: characteristic
Use: Lipopeg® 4-S is a general purpose emulsifier that produces rich, thick creams and lotions. It can be used as the sole emulsifier for systems having required HLB values of 10 to 12. Can be combined with Liposorb® sorbitan esters and ethoxylates or Lipocol® fatty alcohol ethoxylates to provide co-emulsification. Lipopeg® 4-S is especially suitable for skin and hair care treatment preparations and topical pharmaceuticals.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-hamster LD50 19500 uL/kg
Food Research. Vol. 21, Pg. 348, 1956.

oral-hamster LD50 27 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

intraperitoneal-mouse LD50 200 mg/kg
National Technical Information Service. Vol. AD277-689

intravenous-mouse LD50 250 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 38, Pg. 428, 1949.

intravenous-mouse LD50 870 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 38, Pg. 428, 1949.

intravenous-mouse LD50 10000 mg/kg
Bollettino Chimico Farmaceutico. Vol. 101, Pg. 173, 1962.

intravenous-mouse LD50 37000 mg/kg
Bollettino Chimico Farmaceutico. Vol. 101, Pg. 173, 1962.

oral-rabbit LD50 > 12 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

oral-rabbit LD50 > 15 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

oral-rat LD > 10000 mg/kg
Journal of the American College of Toxicology. Vol. 2(7), Pg. 17, 1983.

intraperitoneal-rat LD50 > 9 mL/kg
Journal of the American College of Toxicology. Vol. 2(7), Pg. 17, 1983.

oral-rat LD50 53 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

oral-rat LD50 65 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

oral-rat LD50 > 20000 mg/kg
Archives of Toxicology. Vol. 32, Pg. 245, 1974.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
emulsifiers, surfactants
Recommendation for peg-8 stearate usage levels up to:
 not for fragrance use.
 
Recommendation for peg-8 stearate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NLM Hazardous Substances Data Bank:Search
Cancer Citations:Search
Toxicology Citations:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):9004-99-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24762
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2-hydroxyethyl octadecanoate (peg-8)
Chemidplus:0009004993
 
References:
 2-hydroxyethyl octadecanoate (peg-8)
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:9004-99-3
Pubchem (cid):24762
Pubchem (sid):135018578
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):D01542
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Haz-Map:View
Household Products:Search
ChemSpider:View
Formulations/Preparations:
polyoxyethylene (8) stearate: mixture of mono- & diesters of stearic acid & mixed polyoxyethylene diols having an avg polymer length of 7.5 oxyethylene units.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 algon ST 80
 cithrol 4MS
2-hydroxyethyl octadecanoate (peg-8)
 lipopeg 4-S
 myrj S8
 pegosperse 400 MS
 poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (8 mol EO average molar ratio)
 polyethylene glycol (8) monostearate
 polyethylene glycol (8) stearate
 polyoxyethylene (8) monostearate
 polyoxyethylene (8) stearate
 
 
Notes:
None found
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