EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

trisodium EDTA
acetic acid, (ethylenedinitrilo)tetra-, trisodium salt

Sponsors

Name:trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate
CAS Number: 150-38-9Picture of molecule3D/inchi
Other:8014-66-2
ECHA EINECS - REACH Pre-Reg:205-758-8
FDA UNII:420IP921MB
Nikkaji Web:J10.138I
Molecular Weight:358.19051784
Formula:C10 H13 N2 Na3 O8
NMR Predictor:Predict (works with chrome or firefox)
Category:chelating agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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US Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 614.20 °C. @ 760.00 mm Hg (est)
Flash Point: 617.00 °F. TCC ( 325.20 °C. ) (est)
logP (o/w): -0.434 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: chelating agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Edetate trisodium
Odor: characteristic
Use: Edetate trisodium, a chelating agent that sequesters and decreases the reactivity of metal ions, is used to treat mercury and lead poisoning.
Penta International
EDETATE TRISODIUM 70%
Penta International
EDETATE TRISODIUM 97%
Santa Cruz Biotechnology
For experimental / research use only.
Ethylenediaminetetraacetic acid trisodium salt dihydrate ≥98%
Sigma-Aldrich
For experimental / research use only.
Ethylenediaminetetraacetic acid trisodium salt dihydrate ≥98.0% (KT)
Universal Preserv-A-Chem Inc.
TRISODIUM EDTA LIQUID
Odor: characteristic
Use: Trisodium EDTA is a salt of ethylenediamine tetraacetic acid, and is used in cosmetics and personal care products as a chelating agent with the ability to bind to metal ions. This property allows Trisodium EDTA to assist in preventing the deterioration of formulas, maintaining clarity, protecting fragrance compounds, and preventing rancidity.
Universal Preserv-A-Chem Inc.
TRISODIUM EDTA
Odor: characteristic
Use: Trisodium EDTA is a salt of ethylenediamine tetraacetic acid, and is used in cosmetics and personal care products as a chelating agent with the ability to bind to metal ions. This property allows Trisodium EDTA to assist in preventing the deterioration of formulas, maintaining clarity, protecting fragrance compounds, and preventing rancidity.
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 300 mg/kg
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Revue d'Epidemiologie, Medecine Sociale et Sante Publique. Vol. 10, Pg. 391, 1962.

oral-mouse LD50 2150 mg/kg
Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973

oral-rat LD50 2150 mg/kg
Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: chelating agents
Recommendation for trisodium EDTA usage levels up to:
 not for fragrance use.
 
Recommendation for trisodium EDTA flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):150-38-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9008
National Institute of Allergy and Infectious Diseases:Data
trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate
Chemidplus:0000150389
EPA/NOAA CAMEO:hazardous materials
 
References:
 trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:150-38-9
Pubchem (cid):9008
Pubchem (sid):134973074
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D03947
HMDB (The Human Metabolome Database):Search
FooDB:FDB000749
Household Products:Search
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 chelating agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acetate, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, hydrogen sodium salt (1:1:3)
 acetic acid, (ethylenedinitrilo)tetra-, trisodium salt
 edetate trisodium
 edetic acid trisodium salt
 edta trisodium
 ethylenediamineacetic acid trisodium salt
 ethylenediaminetetraacetic acid trisodium salt
(ethylenedinitrilo)tetraacetic acid trisodium salt
 glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, trisodium salt
 nevanaid-B powder
 sequestrene NA 3
 sodium hydrogen 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate (3:1:1)
 trilon AO
 trisodium 2,2'-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}imino)diacetate
 trisodium edetate
 trisodium ethylenediaminetetraacetate dihydrate
 trisodium ethylenediaminetetraacetate trihydrate
 trisodium hydrogen ethylene diamine tetraacetate
 trisodium versenate
 trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate
 versene 9
 
 
Notes:
Preservative Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)
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