sodium tartrate
butanedioic acid, 2,3-dihydroxy-, sodium salt (1:2)
 
Notes:
Used in food processing as a pH control agent and emulsifier
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disodium 2,3-dihydroxybutanedioate (Click)
CAS Number: 868-18-8Picture of molecule
ECHA EINECS - REACH Pre-Reg: 212-773-3
FDA UNII: QTO9JB4MDD
Nikkaji Web: J367.072D
MDL: MFCD00064874
Molecular Weight: 194.05061856
Formula: C4 H4 Na2 O6
NMR Predictor: Predict (works with chrome or firefox)
Category: sequestrants and stabilizers in meat products and sausage casings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
184.1801 L(+) sodium tartrate View-review
EU SANCO Sodium tartrates View-review
JECFA Food Additive: Sodium L(+)-Tartrate
GSFA Codex: Sodium L(+)-tartrate (335(ii))
DG SANTE Food Additives: sodium tartrate
FDA Mainterm: SODIUM TARTRATE
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1801 Sodium tartrate.
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Physical Properties:
Appearance: colorless crystalline powder (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 399.30 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000000 mm/Hg @ 25.00 °C. (est)
Flash Point: 409.00 °F. TCC ( 209.40 °C. ) (est)
logP (o/w): -1.426 (est)
Soluble in:
 water, 250000 mg/L @ 25 °C (exp)
Insoluble in:
 alcohol
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
odorless
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
American International Chemical
Sodium Tartrate
George Uhe Company
Disodium Tartrate
Kraft Chemical
Sodium Tartrate
Sigma-Aldrich: Sigma
For experimental / research use only.
Sodium tartrate dibasic solution BioUltra, 1.5 M in H2O (colorless solution at 20 °C)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD10  3686 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 12, 1942.

oral-rabbit LDLo  5290 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 512, 1974.

oral-rat LDLo  7500 mg/kg
National Technical Information Service. Vol. OTS0555808

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: sequestrants and stabilizers in meat products and sausage casings
Recommendation for sodium tartrate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium tartrate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the safety of the complexation product of sodium tartrate and iron(III) chloride as a food additive
View page or View pdf
Scientific Opinion on complexation products of sodium tartrates with iron(III) chloride for all animal species and categories
View page or View pdf
EPI System: View
Chemical Carcinogenesis Research Information System: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 868-18-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 13355
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 disodium 2,3-dihydroxybutanedioate
Chemidplus: 0000868188
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References:
 disodium 2,3-dihydroxybutanedioate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 868-18-8
Pubchem (cid): 13355
Pubchem (sid): 134980575
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB016909
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 bisodium tartrate
 butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, disodium salt
 butanedioic acid, 2,3-dihydroxy-, disodium salt, (R*,R*)-(±)-
 butanedioic acid, 2,3-dihydroxy-, sodium salt (1:2)
 disodium (R*,S*)-tartrate
 disodium 2,3-dihydroxybutanedioate
 disodium L-(+)-tartrate
 disodium laevo-(+)-tartrate
 disodium tartarate
 disodium tartrate
 sodium L-(+)-tartrate
 sodium L-tartrate
 sodium laevo-(+)-tartrate
 sodiumtartrate
 tartaric acid disodium salt
 tartaric acid, disodium salt
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Articles:
PubMed: [Strengthening Effects of Sodium Salts on Washing Kerosene Contaminated Soil with Surfactants].
PubMed: Antioxidant effects of pH-regulating agents on the thermal deterioration of vegetable oils.
PubMed: Investigation of radiation sensitivity of some tartrate compounds.
PubMed: Identification and enzymatic characterization of acid phosphatase from Burkholderia gladioli.
PubMed: Technical approaches of a natural dye extracted from Phytolacca americana L.-berries with chemical mordants.
PubMed: Evaluation of hemostatic activity of latex from three Euphorbiaceae species.
PubMed: Subchronic and reproductive/developmental (screening level) toxicity of complexation products of iron trichloride and sodium tartrate (FemTA).
PubMed: Hydrothermal synthesis, characterization and luminescence properties of YbVO4:Ln3+ (Ln3+ = Er3+, Tm3+, Ho3+) nanocrystals.
PubMed: Different secreted phosphatase activities in Leishmania amazonensis.
PubMed: Effect of PEG-salt mixture on the gelation temperature and morphology of MC gel for sustained delivery of drug.
PubMed: Synergistic effect of salt mixture on the gelation temperature and morphology of methylcellulose hydrogel.
PubMed: Identification, crystallization and preliminary X-ray diffraction analysis of esterase A from Caulobacter crescentus CB15, a family VIII lipolytic enzyme.
PubMed: Overexpression, purification, crystallization and preliminary X-ray analysis of putative molybdenum cofactor biosynthesis protein C (MoaC2) from Mycobacterium tuberculosis H37Rv.
PubMed: Crystallization and preliminary X-ray analysis of the haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.
PubMed: Hierarchically nanostructured hydroxyapatite: hydrothermal synthesis, morphology control, growth mechanism, and biological activity.
PubMed: Corrosion protection by sonoelectrodeposited organic films on zinc coated steel.
PubMed: Comparison of two peptide radiotracers for prostate carcinoma targeting.
PubMed: Radiotracers for different angiogenesis receptors in a melanoma model.
PubMed: Dosimetric and kinetic investigations of γ-irradiated sodium tartrate dihydrate.
PubMed: 5-Hydroxytryptophan attenuates somatic signs of nicotine withdrawal.
PubMed: Dopamine D1/5 and D2/3 agonists differentially attenuate somatic signs of nicotine withdrawal in rats.
PubMed: Optical activity and Alfred Werner's coordination chemistry.
PubMed: Role of polymer-protein interaction on partitioning pattern of bovine pancreatic trypsinogen and alpha-chymotrypsinogen in polyethyleneglycol/sodium tartrate aqueous two-phase systems.
PubMed: Biochemical characterization of an acid phosphatase from Thermus thermophilus.
PubMed: Formation and luminescence of sodium rare earth fluoride nanocrystals in the presence of chelators.
PubMed: Determination of fluoride using ion-selective electrodes in the presence of aluminum.
PubMed: [Isolation of heterotrophic nitrifiers/aerobic denitrifiers and their roles in N2O production for different incubations].
PubMed: Purification, crystallization and preliminary X-ray analysis of FliT, a bacterial flagellar substrate-specific export chaperone.
PubMed: Microwave-assisted synthesis of Sb2Se3 submicron rods, compared with those of Bi2Te3 and Sb2Te3.
PubMed: Influences of composition on electroless deposition of silver nanoparticles on glass substrates for surface-enhanced Raman scattering measurements.
PubMed: Separation and determination of nitroaniline isomers by capillary zone electrophoresis with amperometric detection.
PubMed: Aqueous two-phase extraction of nickel dimethylglyoximato complex and its application to spectrophotometric determination of nickel in stainless steel.
PubMed: Cellulose based macromolecular chelator having pyrocatechol as an anchored ligand: synthesis and applications as metal extractant prior to their determination by flame atomic absorption spectrometry.
PubMed: Secreted phosphatase activities in trypanosomatid parasites of plants modulated by platelet-activating factor.
PubMed: Technique for aerosol generation with controllable micrometer size distribution.
PubMed: Evidence for elevated nicotine-induced structural plasticity in nucleus accumbens of adolescent rats.
PubMed: Characterization of a tyrosine phosphatase activity in the oogenesis of Periplaneta americana.
PubMed: Long-term changes in fear conditioning and anxiety-like behavior following nicotine exposure in adult versus adolescent rats.
PubMed: [SEM, XRD and FTIR investigation on crystal growth of calcium oxalate modulated by sodium tartrate].
PubMed: Crystallization and preliminary X-ray characterization of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis.
PubMed: Crystallization and preliminary X-ray diffraction analysis of thioredoxin peroxidase from the aerobic hyperthermophilic archaeon Aeropyrum pernix K1.
PubMed: Tracing the evolution of hepatitis C virus in the United States, Japan, and Egypt by using the molecular clock.
PubMed: An efficient, reproducible and fast preparation of 188Re-anti-CD20 for the treatment of non-Hodgkin's lymphoma.
PubMed: Extraction behavior of metallic contaminants and soil constituents from contaminated soils.
PubMed: Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family.
PubMed: Cloning, purification, crystallization and preliminary crystallographic analysis of acylphosphatase from Pyrococcus horikoshii OT3.
PubMed: Flow calorimetry--a useful tool for determination of immobilized cis-epoxysuccinate hydrolase activity from Nocardia tartaricans.
PubMed: Phosphatase activity on the cell wall of Fonsecaea pedrosoi.
PubMed: Expression and preliminary crystallographic studies of R1E, the large subunit of ribonucleotide reductase from Salmonella typhimurium.
PubMed: Crystallization and preliminary X-ray analysis of a xyloglucan endotransglycosylase from Populus tremula x tremuloides.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of plant ferritin from Glycine max.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa.
PubMed: Crystallization in the presence of glycerol displaces water molecules in the structure of thaumatin.
PubMed: Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.
PubMed: Study on the polarographic catalytic wave of vitamin P in the presence of persulfate and its application.
PubMed: Thermophysical properties of pharmaceutically compatible buffers at sub-zero temperatures: implications for freeze-drying.
PubMed: Platelet-activating factor modulates a secreted phosphatase activity of the trypanosomatid parasite Herpetomonas muscarum muscarum.
PubMed: The effects of pyrantel tartrate on Sarcocystis neurona merozoite viability.
PubMed: A comparison of salts for the crystallization of macromolecules.
PubMed: Purification, crystallization and preliminary X-ray crystallographic analysis of ATP-phosphoribosyltransferase from Escherichia coli.
PubMed: Performance characteristics of PM10 samplers under calm air conditions.
PubMed: Development of a lyophilized kit formulation for labeling of DNA probes with 99mTc.
PubMed: A novel ecto-phosphatase activity of Herpetomonas muscarum muscarum inhibited by platelet-activating factor.
PubMed: [Changes in the threshold values of lingua throughout aging].
PubMed: Modified fluorimetric assay for estimating ampicilloate concentrations and its use for detecting beta-lactamase and penicillin acylase activity in bacteria.
PubMed: Acid phosphatase in the pathogenic and nonpathogenic hemoflagellates, Cryptobia spp., of fishes.
PubMed: Cutaneous sensory nerve formations as studied with impregnation techniques: notes about a simple and reliable method.
PubMed: Modulation of ligand binding to components of the GABAA receptor complex by ammonia: implications for the pathogenesis of hyperammonemic syndromes.
PubMed: Characterization of a life-cycle-stage-regulated membrane protein tyrosine phosphatase in Trypanosoma brucei.
PubMed: Trypanosoma brucei and Trypanosoma cruzi: life cycle-regulated protein tyrosine phosphatase activity.
PubMed: Partial purification and characterization of a soluble protein phosphatase from Leishmania donovani promastigotes.
PubMed: Synthetic Lignin Mineralization by Ceriporiopsis subvermispora Is Inhibited by an Increase in the pH of the Cultures Resulting from Fungal Growth.
PubMed: Leishmanial protein kinase C modulates host cell infection via secreted acid phosphatase.
PubMed: Crystallization and structural analysis of bullfrog red cell L-subunit ferritins.
PubMed: Crystallization and preliminary X-ray analysis of nonglycosylated tissue inhibitor of metalloproteinases-1, N30QN78Q TIMP-1.
PubMed: Evaluation of the toxicity of different metal compounds in the developing brain using aggregating cell cultures as a model.
PubMed: Analysis of the low affinity high capacity estrogenic binding in human benign prostatic hypertrophy.
PubMed: Preparation of the renal function and imaging agent 99mTc-MAG3 starting from S-unprotected mercaptoacetyltriglycine.
PubMed: Ultrastructural and cytochemical study of the odontoclasts in physiologic root resorption of human deciduous teeth.
PubMed: Chemotherapy of trypanosomiasis: the potentiation of antimonial compounds by difluoromethylornithine (DFMO).
PubMed: Determination of copper in white-metal bearing alloys.
PubMed: The gravimetric method for the determination of residual moisture in freeze-dried biological products.
PubMed: Localization of two distinct acid phosphatases in secretory ameloblasts of rat molar tooth germs.
PubMed: Spectrophotometric determination of nickel in copper-base alloy with 2-(2-thiazolylazo)-p-cresol.
PubMed: Aluminum induced encephalopathy in the rat.
PubMed: Comparison of technetium-99m MAG3 kit with HPLC-purified technetium-99m MAG3 and OIH in rats.
PubMed: Studies of aluminum in rat brain.
PubMed: Studies on the enzymes of Sarcocystis suicanis: purification and characterization of an acid phosphatase.
PubMed: Phosphomonoesterases of Leishmania mexicana mexicana and other flagellates.
PubMed: Rapid colorimetric assay for gentamicin injection.
PubMed: Demonstration of various acid hydrolases and preliminary characterization of acid phosphatase in Naegleria fowleri.
PubMed: Enhancement of fluorescence development of end products by use of a fluorescence developer solution in a rapid and sensitive fluorescent spot test for specific detection of microbial beta-lactamases.
PubMed: Effect of pretreatments and fermentation on pore size in cellulosic materials.
PubMed: [A case of urinary schistosomiasis in a Japanese male].
PubMed: Effect of ferric tartrate/sodium hydroxide solvent pretreatment on enzyme hydrolysis of cellulose in corn residue.
PubMed: Determination of arsenic in geological materials by x-ray fluorescence spectrometry after solvent extraction and deposition on a filter.
PubMed: Inhibition by dithionite and reactivation by iron of the tartrate-resistant acid phosphatase in bone of osteopetrotic (ia) rats.
PubMed: Characterization of acid and alkaline phosphatase activity in preparations of tubulin and microtubule-associated proteins.
PubMed: Histochemical identification of osteoclasts. Review of current methods and reappraisal of a simple procedure for routine diagnosis on undecalcified human iliac bone biopsies.
PubMed: Comparison of prostatic acid phosphatase assays.
PubMed: A rapid screening method for heavy metals in biological materials by emission spectroscopy.
PubMed: Antitrypanosomal activity of trivalent antimonials in vitro and its significance.
PubMed: [Zinc activated tartrate resistent phosphatases in the brains of different animal species and their characterization].
PubMed: Fluoremetric determination of methylergonovine maleate and ergonovine maleate in tablets and injections.
PubMed: Determination of serum acid phosphatase in Gaucher's disease using 4-methylumbelliferyl phosphate.
PubMed: Effects of metyrapone and ACTH on intestinal absorption of immunoreactive bovine IgG in cesarean-derived pigs.
PubMed: [The histochemical demonstration of a zinc activated, tartrate resistant acid phosphatase (author's transl)].
PubMed: Clinically available antischistosomal drugs.
PubMed: Life extension in the rotifer Mytilina brevispina var redunca by the application of chelating agents.
PubMed: [The presence and isolation of a highly zinc activated acid phosphatase in the rat brain (author's transl)].
PubMed: [A new variant of acidimetric determination of potassium sodium tartrate in a water-free environment].
PubMed: Experimental and clinical studies with a new antimonial preparation for the treatment of schistosomiasis.
PubMed: Comparative trials of antimonial drugs in urinary schistosomiasis.
PubMed: BIOSYNTHESIS OF NITRO COMPOUNDS. I. NITROGEN AND CARBON REQUIREMENTS FOR THE BIOSYNTHESIS OF BETA-NITROPROPIONIC ACID BY PENICILLIUM ATROVENETUM.
PubMed: [TREATMENT OF SCHISTOSOMIASIS OF THE URINARY BLADDER WITH AN ANTIMONY SODIUM TARTRATE SALT (AN INTENSIVE METHOD)].
PubMed: [Changes in blood cholesterol following experimental lesions of the kidneys induced by corrosive sublimate and by sodium tartrate following serum cholesterol load].
PubMed: [Intensive treatment of American cutaneous leishmaniasis with antimonium sodium tartrate].
PubMed: [Intensive treatment of venereal granuloma with antimony sodium tartrate].
PubMed: [Note on the intensive treatment of American cutaneous leishmaniasis with antimonium sodium tartrate].
PubMed: Further report on the use of bismuth sodium tartrate intravenously in the treatment of 203 additional patients with tularemia.
PubMed: HEMOGLOBIN PRECIPITATION IN RENAL TUBULES : A STUDY OF ITS CAUSES AND EFFECTS.
PubMed: RENAL FUNCTION AS AFFECTED BY EXPERIMENTAL UNILATERAL KIDNEY LESIONS : I. NEPHROSIS DUE TO SODIUM TARTRATE.
PubMed: A NOTE ON THE FATE OF TARTRATES IN THE BODY.
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