EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

sodium sesquicarbonate
carbonic acid, sodium salt (2:3)

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Name:trisodium hydrogen carbonate carbonate
CAS Number: 533-96-0Picture of molecule3D/inchi
Other(deleted CASRN):8014-64-0
ECHA EINECS - REACH Pre-Reg:208-580-9
FDA UNII: Y1X815621J
Beilstein Number:0605456
Molecular Weight:189.99447784
Formula:C2 H Na3 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pH control agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1792 Sodium sesquicarbonate View - review
JECFA Food Additive: Sodium Sesquicarbonate
GSFA Codex: Sodium sesquicarbonate (500(iii))
FDA Regulation:
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1792 Sodium sesquicarbonate.
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 90.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 333.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000026 mmHg @ 25.00 °C. (est)
Flash Point: 338.00 °F. TCC ( 169.80 °C. ) (est)
logP (o/w): -0.809 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
bulking agents
cleansing agents
BOC Sciences
For experimental / research use only.
Sodium sesquicarbonate dihydrate
Universal Preserv-A-Chem Inc.
Odor: characteristic
Use: Sodium sesquicarbonate is used in bath salts, swimming pools, as an alkalinity source for water treatment, and as a phosphate free trisodium phosphate replacement for heavy duty cleaning. Sodium sesquicarbonate is also used in the conservation of copper and copper alloy artefacts that corrode due to contact with salt (called "bronze disease" due to its effect on bronze). It is also used as a precipitating water softener, which combines with hard water minerals (calcium- and magnesium-based minerals) to form an insoluble precipitate, removing these hardness minerals from the water.
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
pH control agents
Recommendation for sodium sesquicarbonate usage levels up to:
 not for fragrance use.
Recommendation for sodium sesquicarbonate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):533-96-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10791
National Institute of Allergy and Infectious Diseases:Data
trisodium hydrogen carbonate carbonate
 trisodium hydrogen carbonate carbonate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:533-96-0
Pubchem (cid):10791
Pubchem (sid):134977211
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
grades: technical; fcc sodium sesquicarbonate dihydrate
Potential Blenders and core components note
None Found
Potential Uses:
 buffering agents
Occurrence (nature, food, other):note
 not found in nature
 carbonic acid sodium salt (2:3)
 carbonic acid, disodium salt, mixt. with monosodium salt
 carbonic acid, sodium salt (2:3)
 magadi soda
 snowflake crystals
 sodium carbonate (3:2)
 sodium carbonate hydrogen carbonate (3:1:1)
 trisodium hydrogen carbonate carbonate
 trisodium hydrogen dicarbonate
 trisodium hydrogendicarbonate


PubMed:Optimized inorganic carbon regime for enhanced growth and lipid accumulation in Chlorella vulgaris.
PubMed:The effect of dietary cation-anion difference concentration and cation source on milk production and feed efficiency in lactating dairy cows.
PubMed:Production of novel microbial flocculants by Klebsiella sp. TG-1 using waste residue from the food industry and its use in defecating the trona suspension.
PubMed:Carbon dioxide capture capacity of sodium hydroxide aqueous solution.
PubMed:[Fossilization of the cells of natronophilic endoevaporite cyanobacterium Euhalothece natronophila in a modelling system ].
PubMed:Bath salts as a "legal high".
PubMed:Trans-18:1 and conjugated linoleic acid profiles after the inclusion of buffer, sodium sesquicarbonate, in the concentrate of finishing steers.
PubMed:The coordinated use of synchrotron spectroelectrochemistry for corrosion studies on heritage metals.
PubMed:A normative study of the components of niprisan--an herbal medicine for sickle cell anemia.
PubMed:Effects of sodium sesquicarbonate on dry matter intake and production of milk and milk components by Holstein cows.
PubMed:Optically detected X-ray absorption spectroscopy measurements as a means of monitoring corrosion layers on copper.
PubMed:Raman spectroscopy of natron: shedding light on ancient Egyptian mummification.
PubMed:Insights into electrolytic stabilization with weak polarization as treatment for archaeological copper objects.
PubMed:Cell for simultaneous synchrotron radiation X-ray and electrochemical corrosion measurements on cultural heritage metals and other materials.
PubMed:Evaluation of corrosion potential measurements as a means to monitor the storage and stabilization processes of archaeological copper-based artifacts.
PubMed:Contribution of trona (magadi) into excessive fluorosis--a case study in Maji ya Chai ward, northern Tanzania.
PubMed:Functional properties of raw and processed pigeonpea (Cajanus cajan) flour.
PubMed:Severe dental fluorosis in a Tanzanian population consuming water with negligible fluoride concentration.
PubMed:Effects of buffers on milk fatty acids and mammary arteriovenous differences in dairy cows fed Ca salts of fatty acids.
PubMed:Sodium sesquicarbonate toxicity in broiler chickens.
PubMed:Dental fluorosis and the use of a high fluoride-containing trona tenderizer (magadi).
PubMed:Natural sodium sesquicarbonate fed for an entire lactation: influence on performance and acid-base status of dairy cows.
PubMed:How safe is the consumption of trona?
PubMed:Ruminal buffers: temporal effects on buffering capacity and pH of ruminal fluid from cows fed a high concentrate diet.
PubMed:A buffer value index to evaluate effects of buffers on ruminal milieu in cows fed high or low concentrate, silage, or hay diets.
PubMed:Dental fluorosis, altitude, and associated dietary factors (short communication).
PubMed:Use of kanwa-cooked cowpea (Vigna unguiculata) in infant food formulation: effect on protein utilization and digestibility.
PubMed:Effects of sodium bicarbonate and sodium sesquicarbonate on animal performance, ruminal metabolism, and systemic acid-base status.
PubMed:Voluntary feed intake, acid-base balance and partitioning of urinary nitrogen in lambs fed corn silage with added sodium bicarbonate or sodium sesquicarbonate.
PubMed:Effects of sodium bicarbonate or sodium sesquicarbonate on lactating Holsteins fed a high grain diet.
PubMed:Sodium sesquicarbonate for early lactation dairy cows fed corn silage-based diets.
PubMed:Trona and sodium bicarbonate in beef cattle diets: effects on pH and volatile fatty acid concentrations.
PubMed:Trona and sodium bicarbonate in beef cattle diets: effects on site and extent of digestion.
PubMed:A study of dermatitis in trona miners and millers.
PubMed:An epidemiologic study of the respiratory effects of trona dust.
PubMed:The nutritive value for rats of high- and low-tannin sorghums treated with magadi soda.
PubMed:Effect of Magadi soda treatment on the tannin content and in-vitro nutritive value of grain sorghums.
abundant salt in east african countries used in treatment of high- & low-tannin grain sorghums to reduce assayable tannins & improve nutritive value of grains; sodium sesquicarbonate salt (mf= na2co3nahco3.h2o). Used as a food additive [EAFUS]
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