potassium tripolyphosphate
triphosphoric acid, potassium salt (1:5)
 
Notes:
Food contaminant derived from its use as a boiler water additive for the prepn. of steam used in food processing. Texturiser and sequestrant in foods, mainly as the K/Na double salt PPPi is a salt or acid that contains three phosphate groups ; ; Triphosphoric acid, also tripolyphosphoric acid, with formula H5P3O10, is a condensed form of phosphoric acid.In polyphosphoric acids, it is the next after pyrophosphoric acid, H4P2O7, also called diphosphoric acid.Compounds such as ATP (adenosine triphosphate) are esters of triphosphoric acid.; ; Polyphosphates are hydrolyzed into smaller units (orthophosphates) in the gut before absorption, which may induce a metabolic acidosis. The acute toxicity of polyphosphonates is low as the lowest LD50 after oral administration is > 1,000 mg/kg body weight.Polyphosphates are moderately irritating to skin and mucous membrane because of their alkalinity.; ; No mutagenic potential was observed when TTP was tested in a Salmonella/microsome assay (Ames test) and in a chromosomal aberration assay in vitro using a Chinese hamster fibroblast cell line (Ishidate et al. 1984). Tetrasodium pyrophosphate was not mutagenic in an in vitro assay using S. cerevisiae strains and S. typhimurium strains with and without the addition of mammalian metabolic activation preparations (IPCS 1982).; ; Reproduction studies in three generations of rats on diets with 0.5% TTP were performed. TTP had no effects on fertility or litter size, or on growth or survival on offspring (Hodge 1964). Tetrasodi
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pentapotassium [oxido(phosphonatooxy)phosphoryl] phosphate (Click)
CAS Number: 13845-36-8Picture of molecule
ECHA EINECS - REACH Pre-Reg: 237-574-9
FDA UNII: NCS08RO8PB
Nikkaji Web: J202.858A
MDL: MFCD00054129
Molecular Weight: 448.40478600
Formula: K5 O10 P3
NMR Predictor: Predict (works with chrome or firefox)
Category: texturizer agents, acidity regulators
 
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 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Potassium tripolyphosphate View-review
JECFA Food Additive: Pentapotassium Triphosphate
GSFA Codex: Pentapotassium triphosphate (451(ii))
FDA Mainterm: POTASSIUM TRIPOLYPHOSPHATE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.310 Boiler water additives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
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Physical Properties:
Appearance: white powder (est)
Assay: 85.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
chelating agents
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Suppliers:
American Elements
Potassium Tripolyphosphate
Foodchem International
Potassium Tripolyphosphate
Kraft Chemical
Potassium Tripolyphosphate
Strem Chemicals
For experimental / research use only.
Potassium triphosphate, 94+%
Zhong Ya Chemical
Potassium Tripolyphosphate
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: texturizer agents, acidity regulators
Recommendation for potassium tripolyphosphate usage levels up to:
 not for fragrance use.
 
Recommendation for potassium tripolyphosphate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 13845-36-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 61695
National Institute of Allergy and Infectious Diseases: Data
 pentapotassium [oxido(phosphonatooxy)phosphoryl] phosphate
Chemidplus: 0013845368
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References:
 pentapotassium [oxido(phosphonatooxy)phosphoryl] phosphate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 13845-36-8
Pubchem (cid): 61695
Pubchem (sid): 135017758
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB013383
Household Products: Search
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 buffering agents 
 chelating agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 pentapotassium [oxido(phosphonatooxy)phosphoryl] phosphate
 pentapotassium triphosphate
 potassium triphosphate (K5P3O10)
 potassium tripolyphosphate
 triphosphoric acid potassium salt (1:5)
 triphosphoric acid, pentapotassium salt
 triphosphoric acid, potassium salt (1:5)
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Articles:
PubMed: Food multiphosphates-preparation and properties.
PubMed: Greater effect of dietary potassium tripolyphosphate than of potassium dihydrogenphosphate on the nephrocalcinosis and proximal tubular function in female rats from the intake of a high-phosphorus diet.
PubMed: Comparison of various phosphate salts as the dietary phosphorus source on nephrocalcinosis and kidney function in rats.
PubMed: Detection of plasma membrane Ca(2+)-ATPase activity in mouse T lymphocytes by flow cytometry using fluo-3-loaded vesicles.
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