potassium sodium tartrate
butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1)
 
Notes:
Used in food processing as an emulsifier and pH control agent It has been used medicinally as a laxative. It has also been used in the process of silvering mirrors. It is an ingredient of Fehling's solution, formerly used in the determination of reducing sugars in solutions.; It is a colorless to blue-white salt crystallizing in the orthorhombic system. Its molecular formula is KNaC4H4O64H2O. It is slightly soluble in alcohol but more completely soluble in water. It has a specific gravity of about 1.79, a melting point of approximately 75 C, and has a saline, cooling taste. As a food additive, its E number is E337.; Potassium sodium tartrate is a double salt first prepared (in about 1675) by an apothecary, Pierre Seignette, of La Rochelle, France. As a result the salt was known as Seignette's salt or Rochelle salt. Rochelle salt is not to be confused with rock salt, which is simply the mineral form of sodium chloride. Potassium sodium tartrate and monopotassium phosphate were the first materials discovered to exhibit piezoelectricity. This property led to its extensive use in "crystal" gramophone (phono) pick-ups, microphones and earpieces during the post-War consumer electronics boom of the mid-20th Century. Such transducers had an exceptionally high output with typical pick-up cartridge outputs as much as 2 volts or more. Rochelle salt is deliquescent so any transducers based on the material deteriorated if stored in damp conditions.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Framingham, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of 30 Sales Representatives, along with our 19 strategically located warehouses are ready to supply product when and where you need it.
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potassium sodium (2R,3R)-2,3-dihydroxybutanedioate (Click)
CAS Number: 304-59-6Picture of molecule
ECHA EINECS - REACH Pre-Reg: 206-156-8
FDA UNII: P49F8NV7ES
Nikkaji Web: J2.573I
MDL: MFCD00065391
Molecular Weight: 210.15914928
Formula: C4 H4 K Na O6
NMR Predictor: Predict (works with chrome or firefox)
Category: sequestrant, emulsifier, stabilizer in cheese products, minced meat, and sausage casings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Sodium potassium tartrate View-review
184.1804 L(+) sodium potassium tartrate View-review
JECFA Food Additive: Potassium Sodium L(+)-Tartrate
GSFA Codex: Potassium sodium L(+)-tartrate (337)
DG SANTE Food Additives: potassium sodium tartrate
FDA Mainterm: SODIUM POTASSIUM TARTRATE
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1804 Sodium potassium tartrate.
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
logP (o/w): -1.080 (est)
Soluble in:
 water, 526000 mg/L @ 25 °C (exp)
Insoluble in:
 alcohol
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
American International Chemical, LLC.
Potassium Sodium Tartrate
Kraft Chemical
Rochelle Salts
Santa Cruz Biotechnology
For experimental / research use only.
Potassium sodium tartrate solution
Sigma-Aldrich: Sigma
For experimental / research use only.
Potassium sodium tartrate solution BioUltra, 1.5 M in H2O
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: sequestrant, emulsifier, stabilizer in cheese products, minced meat, and sausage casings
Recommendation for potassium sodium tartrate usage levels up to:
 not for fragrance use.
 
Recommendation for potassium sodium tartrate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 304-59-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 9357
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 potassium sodium (2R,3R)-2,3-dihydroxybutanedioate
Chemidplus: 0000304596
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References:
 potassium sodium (2R,3R)-2,3-dihydroxybutanedioate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 304-59-6
Pubchem (cid): 9357
Pubchem (sid): 135246642
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
FooDB: FDB016910
Haz-Map: View
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•potassium sodium tartrate, nf for oral admin. many manufacturers market flavored versions. •grades: highest purity, reagent; commercial crystals or powder; national formulary; "food chemicals codex"
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 buffering agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 butanedioic acid, 2,3-dihydroxy- (2R,3R)-, monopotassium monosodium salt
 butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1)
 butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, monopotassium monosodium salt
 butanedioic acid, 2,3-dihydroxy- (theta-(theta,theta))-, monopotassium monosodium salt
 butanedioic acid, 2,3-dihydroxy-, monopotassium monosodium salt
2,3-dihydroxybutanedioic acid monopotassium monosodium salt
2,3-dihydroxybutanedioic acid, monopotassium monosodium salt
monopotassium monosodium 2,3-dihydroxybutanedioate, (R-(R*,R*))-
monopotassium monosodium tartrate
 potassium sodium (2R,3R)-2,3-bis(oxidanyl)butanedioate
 potassium sodium (2R,3R)-2,3-dihydroxybutanedioate
 potassium sodium L-(+)-tartrate
 potassium sodium L(+)-tartrate
 potassium sodium laevo(+)-tartrate
 potassium sodium tartrate anhydrous
 rochelle salt
 seignette salt
 sodium potassium L-tartrate
 sodium potassium salt of L-(+)-tartaric acid
 sodium potassium tartrate
 tartaric acid monopotassium monosodium salt
L-(+)-tartaric acid potassium sodium salt
L()-tartaric acid potassium sodium salt
L(+)-tartaric acid potassium sodium salt
 tartaric acid, monopotassium monosodium salt
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Articles:
PubMed: Investigation of radiation sensitivity of some tartrate compounds.
PubMed: Evaluation of hemostatic activity of latex from three Euphorbiaceae species.
PubMed: Optimization of biodiesel production process from soybean oil using the sodium potassium tartrate doped zirconia catalyst under Microwave Chemical Reactor.
PubMed: Studies on solution-grown pure and doped Sodium Potassium tartrate crystals.
PubMed: Crystallization, X-ray diffraction analysis and SIRAS phasing of human α-L-iduronidase.
PubMed: Identification, crystallization and preliminary X-ray diffraction analysis of esterase A from Caulobacter crescentus CB15, a family VIII lipolytic enzyme.
PubMed: Overexpression, purification, crystallization and preliminary X-ray analysis of putative molybdenum cofactor biosynthesis protein C (MoaC2) from Mycobacterium tuberculosis H37Rv.
PubMed: Crystallization and preliminary X-ray analysis of the haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.
PubMed: Hierarchically nanostructured hydroxyapatite: hydrothermal synthesis, morphology control, growth mechanism, and biological activity.
PubMed: Purification, crystallization and preliminary X-ray analysis of glucokinase from Streptomyces griseus in complex with glucose.
PubMed: Cryoprotection properties of salts of organic acids: a case study for a tetragonal crystal of HEW lysozyme.
PubMed: Formation and luminescence of sodium rare earth fluoride nanocrystals in the presence of chelators.
PubMed: Slow cooling of protein crystals.
PubMed: Purification, crystallization and preliminary X-ray analysis of FliT, a bacterial flagellar substrate-specific export chaperone.
PubMed: Facile fabrication method and characterization of hollow Ag/SiO2 double-shelled spheres.
PubMed: An on-line flow-injection microwave-assisted mineralization and a precipitation/dissolution system for the determination of molybdenum in blood serum and whole blood by electrothermal atomic absorption spectrometry.
PubMed: Technique for aerosol generation with controllable micrometer size distribution.
PubMed: Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Rü61a: a cofactor-devoid dioxygenase of the alpha/beta-hydrolase-fold superfamily.
PubMed: Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence.
PubMed: Crystallization and preliminary X-ray crystallographic studies of the oxidative-stress sensor SoxR and its complex with DNA.
PubMed: Crystallization and preliminary X-ray characterization of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis.
PubMed: Crystallization and preliminary X-ray diffraction analysis of thioredoxin peroxidase from the aerobic hyperthermophilic archaeon Aeropyrum pernix K1.
PubMed: Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family.
PubMed: Cloning, purification, crystallization and preliminary crystallographic analysis of acylphosphatase from Pyrococcus horikoshii OT3.
PubMed: Crystallization and preliminary X-ray analysis of a xyloglucan endotransglycosylase from Populus tremula x tremuloides.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori.
PubMed: Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.
PubMed: Performance characteristics of PM10 samplers under calm air conditions.
PubMed: Development of a lyophilized kit formulation for labeling of DNA probes with 99mTc.
PubMed: Demonstration of the parity-violating energy difference between enantiomers.
PubMed: Altered Ca2+ mobilization during excitation-contraction in cultured cardiac myocytes exposed to antimony.
PubMed: Modified fluorimetric assay for estimating ampicilloate concentrations and its use for detecting beta-lactamase and penicillin acylase activity in bacteria.
PubMed: Crystallization and preliminary studies of lima bean trypsin inhibitor.
PubMed: Purification, characterization and crystallization of Acanthamoeba profilin expressed in Escherichia coli.
PubMed: Crystallization and preliminary X-ray analysis of human angiogenin.
PubMed: Evidence that bismuth salts reduce invasion of epithelial cells by enteroinvasive bacteria.
PubMed: Calcium tartrate gel.
PubMed: Rapid colorimetric assay for gentamicin injection.
PubMed: Determination of reducing sugars in the nanomole range with tetrazolium blue.
PubMed: A modification of the chronic tartrate silver impregnation technique for block impregnation of the central nervous system and paraffin wax embedding.
PubMed: Titrimetric determination of ascorbic acid using chloranil.
PubMed: Determination of arsenic in geological materials by x-ray fluorescence spectrometry after solvent extraction and deposition on a filter.
PubMed: X-ray microanalysis of HeLa S3 Cells. I. Instrumental calibration and analysis of randomly growing cultures.
PubMed: A rapid screening method for heavy metals in biological materials by emission spectroscopy.
PubMed: Electron-cytochemical localization of phospho(enol)pyruvate carboxylase (EC 4.1.1.31) in fungal cells.
PubMed: Biochemical studies with infectious bursal disease virus: comparison of some of its properties with infectious pancreatic necrosis virus.
PubMed: [Use of flocculants for detection of viruses in fluids (author's transl)].
PubMed: Determination of serum proteins in the presence of dextran by means of the biuret reaction.
PubMed: [A new variant of acidimetric determination of potassium sodium tartrate in a water-free environment].
PubMed: Spectrophotometric extractive titrations-IV Determination of zinc in germanium dioxide and germanium chloride.
PubMed: A clinical and serological follow-up of yaws cases treated by acetylarsan and bismuth sodium potassium tartrate.
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