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Category:hair dyeing agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | dark red needles or prisms (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 169.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 386.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 370.00 °F. TCC ( 187.50 °C. ) (est)
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| logP (o/w): | 0.930 |
| Soluble in: |
| | water, 1400 mg/L @ 22 °C (exp) | | | water, 7100 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-dog LDLo 150 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
CARDIAC: OTHER CHANGES
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 20, 1935.
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| Dermal Toxicity: |
subcutaneous-rat LDLo 2100 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 53, Pg. 58, 1935.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | hair dyeing agents |
| Recommendation for picramic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for picramic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1- | amino-2-hydroxy-3,5-dinitrobenzene | | 2- | amino-4,6-dinitrophenol | | 2- | amino-4,6-dinitrophenol (c.i. 76540) | | | c.i. 76540 | | | C.I. oxidation base 21 | | | ci 76540 | | | CI oxidation base 21 | | 4,6- | dinitro-2-amino phenol | | 4,6- | dinitro-2-aminophenol | | | fourrine 4R | | | fourrine 93 | | | furro 4R | | 2- | hydroxy-3,5-dinitroaniline | | | oxidation base 21 | | | phenol, 2-amino-4,6-dinitro- | | | picraminic acid | | | zoba 4R |
Articles:
| PubMed:[Analysis of picric acid and picramic acid in water samples by ultra performance hydrophilic interaction chromatography-tandem mass spectrometry]. |
| PubMed:Amended safety assessment of sodium picramate and picramic acid. |
| PubMed:Tissue distribution and elimination of N-methyl-N-2,4,6-tetranitroaniline (tetryl) in rats. |
| PubMed:Environmental process descriptors for TNT, TNT-related compounds and picric acid in marine sediment slurries. |
| PubMed:Fate and effects of picric acid and 2,6-DNT in marine environments: toxicity of degradation products. |
| PubMed:Spectrophotometric determination of flucloxacillin in pharmaceutical preparations using some nitrophenols as a complexing agent. |
| PubMed:Analysis of polynitrophenols and hexyl by liquid chromatography-mass spectrometry using atmospheric pressure ionisation methods and a volatile ion-pairing reagent. |
| PubMed:Acute toxicity, distribution, and metabolism of 2,4,6-trinitrophenol (picric acid) in Fischer 344 rats. |
| PubMed:Effect of glucose upon alkaline picrate: a Jaffé interference. |
| PubMed:Uptake, elimination, and metabolism of 14C-picric acid and 14C-picramic acid in the American oyster (Crassostrea virginica). |
| PubMed:Bioconcentration and metabolism of picric acid (2,4,6-trinitrophenol) and picramic acid (2-amino-4,6-dinitrophenol) in rainbow trout Salmo gairdneri. |
| PubMed:Conversion of 2,4,6-trinitrophenol to a mutagen by Pseudomonas aeruginosa. |
| PubMed:The effect of 2,4-dinitrophenol and related compounds on bile secretion. |
| PubMed:[Urinary excretion of picric acid, picramic acid and urinary sulfates in experimental tetryl poisoning]. |
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3D/inchi