EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes


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CAS Number: 1120-16-7Picture of molecule3D/inchi
Other(deleted CASRN):8014-77-5
ECHA EINECS - REACH Pre-Reg:214-298-7
Nikkaji Web:J43.223G
XlogP3:3.50 (est)
Molecular Weight:199.33745000
Formula:C12 H25 N O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:viscosity controlling agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 110.00 °C. @ 760.00 mm Hg
Boiling Point: 335.12 °C. @ 760.00 mm Hg (est)
Flash Point: 314.00 °F. TCC ( 156.50 °C. ) (est)
logP (o/w): 4.235 (est)
Soluble in:
 water, 27.72 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: viscosity controlling agents
Kingyoung Bio Technical
For experimental / research use only.
Lauramide >96.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
viscosity controlling agents
Recommendation for lauramide usage levels up to:
 not for fragrance use.
Recommendation for lauramide flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):1120-16-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :14256
National Institute of Allergy and Infectious Diseases:Data
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):14256
Pubchem (sid):134979945
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C13831
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2924.19.8000
Potential Blenders and core components note
None Found
Potential Uses:
 viscosity controlling agents
Occurrence (nature, food, other):note
 not found in nature
 lauric acid amide
 lauric amide
 lauryl amide


PubMed:Synthesis and biological evaluation of a new series of N-acyldiamines as potential antibacterial and antifungal agents.
PubMed:Revised stereochemistry of ceramide-trafficking inhibitor HPA-12 by X-ray crystallography analysis.
PubMed:Susceptibility of Gardnerella vaginalis biofilms to natural antimicrobials subtilosin, ε-poly-L-lysine, and lauramide arginine ethyl ester.
PubMed:Antimicrobial food packaging film based on the release of LAE from EVOH.
PubMed:Influence of dicephalic ionic surfactant interactions with oppositely charged polyelectrolyte upon the in vitro dye release from oil core nanocapsules.
PubMed:Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.
PubMed:Expedient and practical synthesis of CERT-dependent ceramide trafficking inhibitor HPA-12 and its analogues.
PubMed:Construction of an effective screening system for detection of Pseudomonas aeruginosa quorum sensing inhibitors and its application in bioautographic thin-layer chromatography.
PubMed:Experimental and theoretical approach to nonequivalent adsorption of novel dicephalic ammonium surfactants at the air/solution interface.
PubMed:Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels.
PubMed:Pyripyropenes, fungal sesquiterpenes conjugated with alpha-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.
PubMed:Dendritic effect on supramolecular self-assembly: organogels with strong fluorescence emission induced by aggregation.
PubMed:DNA adsorption at liquid/solid interfaces.
PubMed:Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation.
PubMed:The lysophospholipid acyltransferase antagonist CI-976 inhibits a late step in COPII vesicle budding.
PubMed:Highly selective enzymatic kinetic resolution of primary amines at 80 degrees C: a comparative study of carboxylic acids and their ethyl esters as acyl donors.
PubMed:Use of acyltransferase inhibitors to block vesicular traffic between the ER and Golgi complex.
PubMed:Thixotropic organogels based on a simple N-hydroxyalkyl amide: rheological and aging properties.
PubMed:[The molecular machinery CERT for intracellular trafficking of ceramide].
PubMed:Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex.
PubMed:Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking.
PubMed:Stereoselective synthesis and structure-activity relationship of novel ceramide trafficking inhibitors. (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide and its analogues.
PubMed:Catalytic, asymmetric Mannich-type reactions of N-acylimino esters: reactivity, diastereo- and enantioselectivity, and application to synthesis of N-acylated amino acid derivatives.
PubMed:NTP Toxicology and Carcinogenesis Studies of Lauric Acid Diethanolamine Condensate (CAS NO. 120-40-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies).
PubMed:Catalytic, asymmetric Mannich-type reactions of N-acylimino esters for direct formation of N-acylated amino acid derivatives. Efficient synthesis of a novel inhibitor of ceramide trafficking, HPA-12.
PubMed:A novel inhibitor of ceramide trafficking from the endoplasmic reticulum to the site of sphingomyelin synthesis.
PubMed:pH-responsive pseudo-peptides for cell membrane disruption.
PubMed:Determination of fatty acid amides as trimethylsilyl derivatives by gas chromatography with mass spectrometric detection.
PubMed:In vitro and in vivo disposition of 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide (CI-976). Identification of a novel five-carbon cleavage metabolite in rats.
PubMed:Lauramide diethanolamine absorption, metabolism, and disposition in rats and mice after oral, intravenous, and dermal administration.
PubMed:Hydroxylation of lauramide diethanolamine by liver microsomes.
PubMed:Fatty acid discrimination and omega-hydroxylation by cytochrome P450 4A1 and a cytochrome P4504A1/NADPH-P450 reductase fusion protein.
PubMed:The effect of acyl CoA: cholesterol acyltransferase inhibition on the uptake, esterification and secretion of cholesterol by the hamster small intestine.
PubMed:Determination of 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl) dodecanamide, CI-976, in rat plasma by reversed-phase high-performance liquid chromatography.
PubMed:Solubility predictions for solid nitriles and tertiary amides based on the mobile order theory.
PubMed:Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.
PubMed:Biodisposition studies with the acyl-coenzyme A: cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CI-976.
PubMed:Determination of 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide, a lipid regulator, in rat plasma and mesenteric lymph by reversed-phase high-performance liquid chromatography.
PubMed:Facilitated transport of two model steroids by esters and amides of clofibric acid.
PubMed:An appraisal of povidone-iodine and wound healing.
PubMed:Comparison of azone and hexamethylene lauramide in toxicologic effects and penetration enhancement of cimetidine in rabbit eyes.
PubMed:Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents.
PubMed:Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and morphometric evaluation.
PubMed:Metabolism of the acyl-CoA:cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide in rat and monkey. Omega-/beta-oxidation pathway.
PubMed:Percutaneous and systemic disposition of hexamethylene lauramide and its penetration enhancement effect on hydrocortisone in a rat sandwich skin-flap model.
PubMed:Rotation of nucleotide sites is not required for the enzymatic activity of chloroplast coupling factor 1.
PubMed:Contact allergy to cocamide DEA and lauramide DEA in shampoos.
None found
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