hydroxquinoline sulfate
an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. it is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.
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    • Penta International Corporation
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      Q0017 8-Quinolinol Sulfate Monohydrate >98.0%(T)
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quinolin-1-ium-8-ol;sulfate (Click)
CAS Number: 134-31-6Picture of molecule
ECHA EINECS - REACH Pre-Reg: 205-137-1
MDL: MFCD00013095
Molecular Weight: 388.39972000
Formula: C18 H16 N2 O6 S
NMR Predictor: Predict (works with chrome or firefox)
Category: antimicrobial agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Physical Properties:
Appearance: pale yellow to yellow crystalline powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 177.50 °C. @ 760.00 mm Hg
Boiling Point: 267.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.005080 mm/Hg @ 25.00 °C. (est)
Flash Point: 290.00 °F. TCC ( 143.10 °C. ) (est)
logP (o/w): 1.870 (est)
Soluble in:
 water, 1.00E+06 mg/L @ 25 °C (exp)
 water, 35.66 mg/L @ 25 °C (est)
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Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antimicrobial agents
emulsion stabilisers
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BOC Sciences
For experimental / research use only.
Quinoline Sulphate 95%
For experimental / research use only.
8-Hydroxquinoline Sulfate
Charkit Chemical
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
8-Quinolinol hemisulfate salt 97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
8-Hydroxyquinoline hemisulfate salt hemihydrate 98%
For experimental / research use only.
8-Quinolinol Sulfate Monohydrate >98.0%(T)
Universal Preserv-A-Chem Inc.
Odor: characteristic
Use: Is used as a chelating agent in the pharmaceutical industry and has antimicrobial properties.
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LDLo  1200 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 28, Pg. 484, 1931.

oral-mouse LD50  280 mg/kg
"Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.

unreported-mouse LDLo  50 mg/kg
Journal of the American Chemical Society. Vol. 60, Pg. 1582, 1938.

oral-rat LD50  1200 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C67, 1991.

Dermal Toxicity:
skin-rat LD50 > 4000 mg/kg
"Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A229, Pg. 1983

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antimicrobial agents
Recommendation for hydroxquinoline sulfate usage levels up to:
 not for fragrance use.
Recommendation for hydroxquinoline sulfate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the modification of the existing MRL for 8-hydroxyquinoline in tomatoes
View page or View pdf
EPI System: View
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
Toxicology Citations: Search
EPA GENetic TOXicology: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 134-31-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 8639
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0000134316
EPA/NOAA CAMEO: hazardous materials
RTECS: VC8260000 for cas# 134-31-6
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 134-31-6
Pubchem (cid): 8639
Pubchem (sid): 134974918
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2933.49.7000
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
None Found
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Potential Uses:
 antimicrobial agents 
 emulsion stabilisers 
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Occurrence (nature, food, other): note
 not found in nature
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8-hydroxquinoline sulfate
8-hydroxyquinoline hemisulfate salt
8-hydroxyquinoline hemisulfate salt hemihydrate
 hydroxyquinoline sulfate
8-hydroxyquinoline sulfate
bis(8-hydroxyquinolinium) sulfate
bis(8-hydroxyquinolinium) sulphate
 quinolin-8-ol sulfate (2:1)
oxyquinoline sulfate
8-quinolinol hemisulfate salt
8-quinolinol hemisulfate salt hemihydrate
8-quinolinol sulfate (2:1)
8-quinolinol sulfate monohydrate
8-quinolinol sulfate(2:1)
8-quinolinol sulphate
8-quinolinol, sulfate (2:1) (salt)
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PubMed: Final amended report on the safety assessment of oxyquinoline and oxyquinoline sulfate as used in cosmetics.
PubMed: [Study of a drug combination with contraceptive, antibacterial, antimycotic and prophylactic action, for topical use in venereal diseases. 4. Effect of the combination of oxyquinoline sulfate, copper sulfate and lactic acid on Trichomonas vaginalis and on Candida albicans in vivo].
PubMed: [Study of a topical antibacterial, contraceptive, antifungal and anti-venereal pharmacological combination. III. Post-coital test of the spermicidal action of a combination of oxyquinoline sulfate, copper sulfate and lactic acid].
PubMed: [Study of a drug combination for topical use, with contraceptive, antibacterial and antimycotic action and venereal disease preventive action. II. Optical microscopic and scanning microscopic studies of morphological changes of human spermatozoa in vitro after contact with the oxyquinoline sulfate and copper sulfate association].
PubMed: [Study of a drug combination for topical use, with contraceptive, antibacterial, antimycotic and prophylactic action for venereal diseases. I. Effect of oxyquinoline sulfate and copper sulfate on the motility and morphology of human spermatozoa in vitro].
PubMed: Quantitative determinations of antipyrine and benzocaine in ear drops by high-pressure liquid chromatography.
PubMed: [Oxyquinoline sulfate].
PubMed: [Not Available].
PubMed: A method of testing the relative spermicidal effectiveness of contraceptives, and its application to ten commercial products.
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