vitamin K1
phytonadione

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• 
  American International Chemical, Inc.

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  CODE129698 CODE129698
  Product(s):
  K11AUP Vitamin K1 (Phytonadione) 1 Trituration
  VK1AUL Vitamin K1 USP (Phytonadione)

• 
  BOC Sciences

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  CODE129698 CODE129698
  Product(s):
  84-80-0 Vitamin K1 (E-Phytonadione) >98%
  Vitamin K1 is widely existed in green plants, photosynthetic bacteria and algae. Dietary Supplement

• 
  Charkit Chemical Corporation

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  about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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  CODE129698 CODE129698
  Product(s):
  VITAMIN K1 (PHYTONADIONE 1%)ON DCP

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  Glentham Life Sciences Ltd

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  GV4612 Vitamin K1

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  Penta International Corporation

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  At Penta, our products and services help businesses do business better.
  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  Product(s):
  22-90250 VITAMIN K1 (PHYTONADIONE)
  22-90255 VITAMIN K1 (PHYTONADIONE) USP

Name: 2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione CAS Number: 84-80-0 3D/inchi Other(deleted CASRN): 10485-69-5 ECHA EINECS - REACH Pre-Reg: 201-564-2 FDA UNII: S5Z3U87QHF Nikkaji Web: J20.960K Beilstein Number: 2568816 MDL: MFCD00214063 XlogP3-AA: 10.90 (est) Molecular Weight: 450.70602000 Formula: C31 H46 O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:dietary supplements   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: pale yellow to yellow amber oils to solid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 0.98400 @ 25.00 °C. Melting Point: -20.00 °C. @ 760.00 mm Hg Boiling Point: 546.00 to 547.00 °C. @ 760.00 mm Hg (est) Boiling Point: 140.00 °C. @ 0.01 mm Hg Flash Point: > 230.00 °F. TCC ( > 110.00 °C. ) logP (o/w): 10.305 (est) Soluble in:   alcohol   water, 1.482e-007 mg/L @ 25 °C (est) Insoluble in:   water   Organoleptic Properties: Odor Strength:none Odor Description:at 100.00 %. odorless Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: AIDP K-Shield™ (Stabilized K1) Phytonadione, phylloquinone 1% American International Chemical, LLC. Vitamin K1 (Phytonadione) 1 Trituration American International Chemical, LLC. Vitamin K1 USP (Phytonadione) BASF Dry Vitamin K1 BOC Sciences For experimental / research use only. Vitamin K1 (E-Phytonadione) >98% Odor: characteristic Use: Vitamin K1 is widely existed in green plants, photosynthetic bacteria and algae. Dietary Supplement Charkit Chemical VITAMIN K1 (PHYTONADIONE 1%)ON DCP Farbest-Tallman Foods Vitamin K1 100% Oil Flavor: bland It is used in dietary supplement applications including soft gel capsules. Foodchem International Vitamin K1 Glentham Life Sciences Vitamin K1 Graham Chemical Vitamin K1 Indis NV For experimental / research use only. Vitamin K1 Penta International VITAMIN K1 (PHYTONADIONE) USP Penta International VITAMIN K1 (PHYTONADIONE) Qingdao Dacon Trading Vitamin K1 Sigma-Aldrich: Sigma For experimental / research use only. Vitamin K1 BioXtra, ≥99.0% (sum of isomers, HPLC), mixtur of isomers sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 > 33487 mg/kg German Offenlegungsschrift Patent Document. Vol. #2808572 oral-mouse LD50 25000 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 1339, 1967. intravenous-mouse LD50 > 6570 mg/kg Drugs in Japan Vol. 6, Pg. 653, 1982. intramuscular-man TDLo 11429 ug/kg/8D BLOOD: EOSINOPHILIA SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Dermatology. Vol. 121, Pg. 1421, 1985. Dermal Toxicity: subcutaneous-mouse LDLo 1000 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 25, 1958. Inhalation Toxicity: Not determined   Safety in Use Information: Category: dietary supplements Recommendation for vitamin K1 usage levels up to:   not for fragrance use.   Recommendation for vitamin K1 flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):84-80-0 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :5280483 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione Chemidplus:0000084800 RTECS:QJ5800000 for cas# 84-80-0   References:   2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 84-80-0 Pubchem (cid): 5280483 Pubchem (sid): 134972505   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): C02059 HMDB (The Human Metabolome Database): HMDB03555 FooDB: FDB023333 YMDB (Yeast Metabolome Database): YMDB01526 Export Tariff Code: 2936.29.2000 FDA Listing of Food Additive Status: View MedlinePlusSupp: View VCF-Online: VCF Volatile Compounds in Food ChemSpider: View Wikipedia: View Formulations/Preparations: •phytonadione, usp (vit k1, aquamephyton, konakion, mephyton)marketed in 5-mg tablets, & in ampuls containing emulsion of 2 or 10 mgml of phytonadione dispersed in soln of buffered polysorbate & propylene glycol (konakion) or polyethylated fatty acid deriv & dextrose (aquamephyton). •konakion is admin only im; aquamephyton may be given by any parenteral route. •colloidal soln is marketed under name aqua-mephyton. •oral tablets; 5 mg, mephyton (scored) merck. •phylloquinone is available as a 5 and 10 mg tablet (chewable), a 2 and 10 mgml injection solution, a 10 and 20 mgml oral solution, and a 20 mgml emulsion. phylloquinone is also available as a component (200 ug) of a multivitamin lyophilized, sterile powder intended for reconstitution and dilution in intravenous infusions, as a component (0.075 mg) of and effervescent multivitamin tablet, and as a component (5.5 ug) of a multivitamin infant formula. •parenteral injection; 2 mgml, aquamephyton (with polyoxyethylated fatty acid derivative, dextrone, and benzyl alcohol 0.9%), merck. 10 mgml, aquamephyton (with polyoxyethylated fatty acid derivative, dextrose, and benzyl alcohol 0.9%), merck.   Potential Blenders and core components note None Found   Potential Uses:   biological additives   Occurrence (nature, food, other):note   alfalfa Search Trop Picture   anise leaf Search Trop Picture   anise root Search Trop Picture   anise tissue culture Search Trop Picture   apple fruit Search Trop Picture   asparagus plant Search Trop Picture   avocado fruit Search Trop Picture   banana fruit Search Trop Picture   barley leaf Search Trop Picture   barley root Search Trop Picture   barley seed Search Trop Picture   barley tissue culture Search Trop Picture   bean black bean fruit Search Trop Picture   bean black bean plant Search Trop Picture   bean black bean seed Search Trop Picture   bean fava bean seed Search Trop Picture   bean scarlet runner bean fruit Search Trop Picture   bilberry fruit Search Trop Picture   blueberry fruit Search Trop Picture   broccoli asparagus broccoli inflorescence Search Trop Picture   broccoli asparagus broccoli leaf Search Trop Picture   brussel sprout plant Search Trop Picture   cabbage flower Search Trop Picture   cacao bean Search Trop Picture   canola oil Search Trop Picture   cantaloupe fruit Search Trop Picture   carrot plant Search Trop Picture   cayenne fruit Search Trop Picture   celery seed Search Trop Picture   chestnut sweet chestnut Search Trop Picture   chickpea seed Search Trop Picture   coconut oil Search Trop Picture   corn fruit Search Trop Picture   corn oil Search Trop Picture   corn silk Search Trop Picture   cotton seed oil Search Trop Picture   cranberry fruit Search Trop Picture   cucumber plant Search Trop Picture   currant black currant fruit Search Trop Picture   date palm fruit Search Trop Picture   dill seed Search Trop Picture   fenugreek plant Search Trop Picture   fig fruit Search Trop Picture   grape fruit Search Trop Picture   lentil seed Search Trop Picture   lettuce leaf Search Trop Picture   oat seed Search Trop Picture   okra plant Search Trop Picture   olive oil Search Trop Picture   orange fruit Search Trop Picture   parsley leaf Search Trop Picture   pea plant Search Trop Picture   pepper bell pepper fruit Search Trop Picture   pineapple fruit Search Trop Picture   plum fruit Search Trop Picture   potato tuber Search Trop Picture   rapini root Search Trop Picture   soybean oil Search Trop Picture   soybean seed Search Trop Picture   soybean seed oil Search Trop Picture   spinach leaf Search Trop Picture   spinach tuber Search Trop Picture   sunflower seed oil Search Trop Picture   tea leaf Search Trop Picture   tomato plant Search Trop Picture   watercress leaf Search Trop Picture   watermelon fruit Search Trop Picture   wheat leaf Search Trop Picture   Synonyms:   aquamephyton   dry vitamin K1   K-shield (stabilized K1) phytonadione, phylloquinone 1% 2- methyl-3-[(2E)-3,7,11,15-tetramethyl-2-hexadecen-1-yl]-1,4-naphthoquinone 2- methyl-3-[(2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1,4-naphthoquinone 2- methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione 1,4- naphthalenedione, 2-methyl-3-[(2E)-3,7,11,15-tetramethyl-2-hexadecen-1-yl]-   phylloquinone   phytonadione 3-((2E)-3,7,11,15- tetramethylhexadec-2-enyl)-2-methylnaphthalene-1,4-dione   vitamin K1 (phytonadione) 1 trituration   vitamin K1 100% oil   vitamin K1 USP (phytonadione)   Articles:   None found yet. Try the PubMed Search.

Notes: a family of phylloquinones that contains a ring of 2-methyl-1,4-naphthoquinone and an isoprenoid side chain. members of this group of vitamin k 1 have only one double bond on the proximal isoprene unit. rich sources of vitamin k 1 include green plants, algae, and photosynthetic bacteria. vitamin k1 has antihemorrhagic and prothrombogenic activity. Widely distributed in green leaves and vegetables, esp. cabbage and spinach. Infant formula fortifier Vitamin K is a family of fat-soluble compounds with a common chemical structure, 2, methyl-1,4-napthoquinone. Phylloquinone is present in food of plant origin, such as green, leafy vegetables and certain plant oils, and is the predominant form in the diet. Bacterial and other forms of vitamin K, referred to as the menaquinones, differ in structure from phylloquinone in their 3-substituted lipophilic side chain. Menaquinone-4 (MK-4), which is alkylated from menadione, is present in animal feeds or is the product of tissue-specific conversion directly from dietary phylloquinone. Vitamin K is a cofactor specific to the formation of gamma-carboxyglutamyl (Gla) residues in certain proteins, including prothrombin necessary for normal hemostatic function. The naturally occurring forms of vitamin K are quinones (i.e. phylloquinone and menaquinones) so vitamin K is reduced to the vitamin K hydroquinone prior to catalyzing the gamma-carboxylation reaction. The active site for the carboxylation reaction is on the napthoquinone ring, which is identical for all forms of vitamin K, including phylloquinone and MK-4. (PMID 16857056) [HMDB]