tyloxapol, 25301-02-4

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CODE129603 CODE129603
Product(s):
25301-02-4 Tyloxapol 95%
Tyloxapol, a nonionic liquid polymer, is a surfactant to aid liquefaction.

Penta International Corporation

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CODE129603 CODE129603
Product(s):
20-87600 TYLOXAPOL USP

Name:	formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
CAS Number:	25301-02-4	3D/inchi
Other(deleted CASRN):	9014-50-0
FDA UNII:	Y27PUL9H56
MDL:	MFCD00149002
Molecular Weight:	280.40776000
Formula:	C17 H28 O3
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:pharmaceuticals / chemical synthisis

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Boiling Point:	282.30 °C. @ 760.00 mm Hg (est)
Vapor Pressure:	0.001980 mmHg @ 25.00 °C. (est)
Flash Point:	> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w):	4.930 (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

Tyloxapol 95%

Odor: characteristic

Use: Tyloxapol, a nonionic liquid polymer, is a surfactant to aid liquefaction.

Carbosynth

For experimental / research use only.

Tyloxapol

Penta International

TYLOXAPOL USP

Santa Cruz Biotechnology

For experimental / research use only.

Tyloxapol

Sigma-Aldrich: Sigma

For experimental / research use only.

Tyloxapol BioXtra

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 > 5000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. intravenous-mouse LD50 > 3800 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. oral-mouse LD50 > 10000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. intraperitoneal-rat LD50 > 5000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. intravenous-rat LD50 1800 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. oral-rat LD50 > 5000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982.
Dermal Toxicity:
subcutaneous-mouse LD50 > 5000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982. subcutaneous-rat LD50 > 5000 mg/kg Drugs in Japan Vol. 6, Pg. 467, 1982.
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
pharmaceuticals / chemical synthisis
Recommendation for tyloxapol usage levels up to:
	not for fragrance use.

Recommendation for tyloxapol flavor usage levels up to:
	not for flavor use.

Safety References:

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :71388

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol

Chemidplus:0025301024

RTECS:SM9750000 for cas# 25301-02-4

References:

	formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	25301-02-4
Pubchem (cid):	71388
Pubchem (sid):	135029958

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	3402.90.3000
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

	alevaire
	enuclene
	exosurf
	formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
	macrocyclon
	superinone
	superiuone
	triton A-20
	triton WR 1339
	triton WR-1339
	tyloxypal

Articles:

PubMed:Hippocampal lipoprotein lipase regulates energy balance in rodents.

PubMed:In vitro antioxidant and antihyperlipidemic activities of Toddalia asiatica (L) Lam. leaves in Triton WR-1339 and high fat diet induced hyperlipidemic rats.

PubMed:The effects of the decaffeination of coffee samples on platelet aggregation in hyperlipidemic rats.

PubMed:Acute central neuropeptide Y administration increases food intake but does not affect hepatic very low-density lipoprotein (VLDL) production in mice.

PubMed:Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion.

PubMed:Glycoprotein (90 kDa) isolated from Opuntia ficus-indica var. saboten MAKINO lowers plasma lipid level through scavenging of intracellular radicals in Triton WR-1339-induced mice.

PubMed:Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4.

PubMed:CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans.

PubMed:Hypolipidaemic activity of seaweed from Karachi coast.

PubMed:Surfactant-enhanced biodegradation of high molecular weight polycyclic aromatic hydrocarbons by stenotrophomonas maltophilia

PubMed:Alimentary lipemia is enhanced in fiber-fed rats.

PubMed:From the Food and Drug Administration.

PubMed:Voluntary food consumption and gastric emptying in rats given intravenous Triton WR-1339.

Notes:

non-ionic detergent with surface-active properties; incompatible with metals; surfactant also used in inhalation therapy; n1 is from ca vol 90 form index.

tyloxapol triton A-20

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Articles:

tyloxapol
triton A-20