trypsin
tryptase

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  CODE129583 CODE129583
  Product(s):
  9002-07-7 Trypsin 95%

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  Glentham Life Sciences Ltd

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  CODE129583 CODE129583
  Product(s):
  GE3976 Trypsin

Name: acetic acid;tert-butylN-[(2S)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(5-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan- CAS Number: 9002-07-7 3D/inchi Other(deleted CASRN): 146990-35-4 ECHA EINECS - REACH Pre-Reg: 232-650-8 FDA UNII: GV54A213NN Molecular Weight: 725.80059000 Formula: C35 H47 N7 O10 NMR Predictor: Predict (works with chrome, Edge or firefox) Category:enzyme preparations and microorganisms   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Additive: Trypsin FDA Mainterm (SATF): 9002-07-7 ; TRYPSIN FROM ANIMAL TISSUE FDA Regulation: FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 184.1914 Trypsin.   Physical Properties: Appearance: white to tan powder (est) Food Chemicals Codex Listed: No Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est) logP (o/w): 2.798 (est) Soluble in:   water Insoluble in:   alcohol   chloroform   ether   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: hair conditioning skin conditioning   Suppliers: American Laboratories Trypsin 1:100 Powder 051 American Laboratories Trypsin 1:100 Powder 90B American Laboratories Trypsin 1:125 Powder 463 American Laboratories Trypsin 1:150 Powder 527 American Laboratories Trypsin 1:150 Powder 91B American Laboratories Trypsin 1:200 Powder 530 American Laboratories Trypsin 1:25 Powder 540 American Laboratories Trypsin 1:25 Powder 94B American Laboratories Trypsin 1:250 Granular 750 American Laboratories Trypsin 1:250 Powder 052 American Laboratories Trypsin 1:75 Powder 529 American Laboratories Trypsin 1:75 Powder 89B American Laboratories Trypsin 1:80 Powder 053 BOC Sciences For experimental / research use only. Trypsin 95% Glentham Life Sciences Trypsin Indis NV For experimental / research use only. Trypsin Pangaea Sciences Trypsin USP Sigma-Aldrich: Sigma For experimental / research use only. Trypsin from bovine pancreas sds TPCK Treated, essentially salt-free, lyophilized powder, ≥10,000 BAEE units/mg prote   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 > 5000 mg/kg Drugs in Japan Vol. -, Pg. 744, 1990. intravenous-rat LD50 36 mg/kg Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982. intraperitoneal-rat LD50 > 51 mg/kg Drugs in Japan Vol. -, Pg. 744, 1990. intravenous-guinea pig LDLo 30000 units/kg BLOOD: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 164, 1956. intramuscular-mouse LD50 105 mg/kg Drugs in Japan Vol. -, Pg. 744, 1990. intraperitoneal-mouse LD50 100 mg/kg Farmakologiya i Toksikologiya Vol. 45(6), Pg. 78, 1982. intravenous-mouse LD50 11100 ug/kg Drugs in Japan Vol. 6, Pg. 523, 1982. oral-mouse LD50 1450 mg/kg Drugs in Japan Vol. -, Pg. 744, 1990. intravenous-rabbit LD50 2200 ug/kg Drugs in Japan Vol. 6, Pg. 523, 1982. intramuscular-rat LD50 200 mg/kg Drugs in Japan Vol. -, Pg. 744, 1990. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: enzyme preparations and microorganisms Recommendation for trypsin usage levels up to:   not for fragrance use.   Recommendation for trypsin flavor usage levels up to:   not for flavor use.   Safety References: European Food Safety Authority (EFSA) reference(s): Safety evaluation of a food enzyme containing trypsin and chymotrypsin from porcine pancreas View page or View pdf Safety evaluation of a food enzyme containing trypsin, chymotrypsin, elastase and carboxypeptidase from porcine pancreas View page or View pdf Safety evaluation of a food enzyme containing trypsin and chymotrypsin from porcine pancreas View page or View pdf Safety evaluation of food enzyme trypsin from porcine pancreas View page or View pdf ClinicalTrials.gov:search Daily Med:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):9002-07-7 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :5311489 National Institute of Allergy and Infectious Diseases:Data acetic acid;tert-butylN-[(2S)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(5-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan- Chemidplus:0009002077 RTECS:YN5075000 for cas# 9002-07-7   References:   acetic acid;tert-butylN-[(2S)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(5-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan- NIST Chemistry WebBook: Search Inchi Pubchem (cid): 5311489 Pubchem (sid): 135362417   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View HMDB (The Human Metabolome Database): Search FooDB: FDB001085 Export Tariff Code: 3507.90.0000 FDA Listing of Food Additive Status: View VCF-Online: VCF Volatile Compounds in Food ChemSpider: View Wikipedia: View Wikipedia2: View2 Formulations/Preparations: each milligram contains not less than 2500 nf trypsin units. it is marketed as powder & as trypsin crystallized for aerosol, nf, 250,000 nf unitsml. it is also available in combination with chymotrypsin as tablet.   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   trypsin Search PMC Picture   Synonyms:   parenzymol   trypsin 1:100 powder 051   trypsin 1:100 powder 90b   trypsin 1:125 powder 463   trypsin 1:150 powder 527   trypsin 1:150 powder 91b   trypsin 1:200 powder 530   trypsin 1:25 powder 540   trypsin 1:25 powder 94b   trypsin 1:250 granular 750   trypsin 1:250 powder 052   trypsin 1:75 powder 529   trypsin 1:75 powder 89b   trypsin 1:80 powder 053   trypsin from animal tissue   trypsin USP   tryptase   Articles:   None found yet. Try the PubMed Search.

Notes: Used in baking, meat tenderising, and production of protein hydrolysates One consequence of the autosomal recessive disease cystic fibrosis is a deficiency in transport of trypsin and other digestive enzymes from the pancreas. This leads to the disorder termed meconium ileus. This disorder involves intestinal obstruction (ileus) due to overly thick meconium which is normally broken down by trypsins and other proteases, then passed in feces.; Trypsin (EC 3.4.21.4) is a serine protease found in the digestive system of many vertebrates, where it hydrolyses proteins. Trypsin is produced in the pancreas as the inactive proenzyme trypsinogen. Trypsin predominantly cleaves peptide chains at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline. It is used for numerous biotechnological processes. The process is commonly referred to as trypsin proteolysis or trypsinisation and proteins that have been digested/treated with trypsin are said to have been trypsinized.